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225 articles for “Controlled Release”
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Microencapsulation Technology and It’s Application in Dairy Industry: A Review
Abstract: Microencapsulation of bioactive compound or nutrient is one of the important applications in dairy and food industry. Microencapsulation is an attractive technique to enhance the stability of bioactive compounds with controlled release. This article provides an overview of various encapsulation techniques such as spray drying, fluidized-bed drying, solvent evaporation, coacervation and extrusion method, and different encapsulated bioactive compounds or nutrient which have been used for the fortification of dairy products …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 10, Issue 3, 2021 · pp. 1–7 Read article
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Pastillation—Towards Next Generation Particle Engineering
Abstract: Particle engineering is quiet essential nowadays in order to get desired qualities for generating stable formulation with improved therapeutic credentials. The current pharmaceutical technology has already realized the tremendous potential of controlled release multiparticulate system in terms of its flexibility in product development and therapeutic benefits to the patients in comparison to the conventional single unit dosage form. Pastillation provides an efficient, cost-effective process for the continuous converting of molten …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 3, Issue 2, 2016 · pp. 36–43 Read article
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Development and Characterization of 5-Fluorouracil Cubosomal Nanosponge Tablet for Colon Targeting
Abstract: The objective of this study was to develop nano-scale delivery system to improve nanometric size range, percentage drug entrapment efficiency, controlled release of the incorporated drug and the protection against degradation. 5-FU loaded cubosomal dispersion was prepared by the bottom up technique and formulation was characterized. From this, 5-FU cubosomal nanosponges were prepared by the emulsion solvent diffusion method using various pH dependent polymers and evaluated, encapsulation of this formulation …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 10, Issue 2, 2019 · pp. 9–18 Read article
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Microsphere: A Novel Drug Delivery System Approach
Abstract: Microspheres are the multiarticulate novel drug delivery dosage form, it contains the particle size range from 1 to 50 µ and characteristically spherical in shape with free flow property. It is widely known as “Microparticles”. Microspheres are prepared by covering the drug particles with polymeric solution (obtained in natural, semisynthetic or synthetic form) to achieve controlled release of drug, which produces prolonged action with reduced toxicity at the specified site …
Published in Trends in Drug Delivery · Vol. 6, Issue 1, 2019 · pp. 24–30 Read article
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Liquid Crystals as Novel Drug Carrier: A Review
Abstract: Liquid crystal is a thermodynamic stable phase characterized by anisotropic properties, generally lying in the temperature range between the solid and isotropic liquid phase, hence are termed mesophase. Based on the way that liquid crystals are obtained, they can be classified into two types—thermotropic liquid crystals and lyotropic liquid crystals. The thermotropic liquid crystal is generated by variation of temperature in the liquid state, while the lyotropic liquid crystal is …
Published in Trends in Drug Delivery · Vol. 2, Issue 1, 2015 · pp. 1–9 Read article
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Formulation Development and Evaluation Technique for Immediate and Modified Release Capsule
Abstract: The development and evaluation of formulations for immediate-release (IR) and modified-release (MR) capsules represent a critical aspect of pharmaceutical dosage form design, offering distinct advantages in terms of drug release profiles and therapeutic outcomes. This study focuses on the formulation strategies, techniques, and evaluation methods used to develop both IR and MR capsules. Immediate-release capsules are designed to disintegrate quickly in the gastrointestinal tract, ensuring rapid drug absorption, while modified-release …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 1–9 Read article
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Formulation Development of Antihypertensive Buccal Patches and Characterisation
Abstract: Buccal patches containing atenolol and nifedipine were fabricated from mucoadhesive polymers like chitosan and hydroxypropyl methylcellulose (HPMC) 15CPS for the purpose of prolonging drug release and improving their bioavailability. The fabricated films were smooth, uniform and the colour was brown with good flexibility. The weight and thickness of all the formulations were found to be uniform. The drug content was in the range of 95–98%, indicating drug uniformity. Swelling index …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 2, Issue 2, 2015 · pp. 15–27 Read article
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Architectured Multiphase Polymeric Carriers with Microstructural Gradients: Synergistic Filler Effects for the Precision Delivery in Tuberous Plant Systems
Abstract: In this paper, 50 papers were reviewed to analyse the design, techniques, and applications of polymer composite systems for delivering agrochemicals against major tuberous plant pathogens, including fungi, bacteria, and nematodes. Primary tuber plant pathogens affecting yield are studied, followed by a study of control strategies. This is followed by a study of the basic properties of polymer composites, including the significance of natural and synthetic polymers. Then, the study …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 940–949 Read article
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Polysaccharide-Based Hydrogels for Sustained Drug Release in Pharmacology
Abstract: Polysaccharide-based hydrogels have showed great potential in medicine as materials for long-lasting, under control medication delivery systems. Natural polysaccharides include chitosan; alginate, agarose, and cellulose form these hydrogels. Among its many advantages are biocompatibility, biodegradability, and customising ability for various drug release rates. Reacting to pH, temperature, and ionic strength changes in the surroundings, polysaccharide-based hydrogels may swell. For usage requiring the release of therapeutic substances over an extended period …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 300–312 Read article
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Development and Characterization of Mucoadhesive Microspheres Containing a Model Antidiabetic Drug
Abstract: The present work was envisaged to reduce the dosing frequency and improve patient compliance by designing and evaluating sustained release mucoadhesive (SRM) microspheres of metformin hydrochloride (MH) for an effective control of diabetes type-2. Microspheres were prepared by emulsification solvent evaporation method using sodium alginate, carbopol 934P (CP), and sodium carboxy methyl cellulose (SCMC) as a mucoadhesive polymers. The microspheres exhibits good mucoadhesive properties and showed high drug entrapment efficiency. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 2, Issue 2, 2015 · pp. 12–19 Read article
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Colloidosomes: An Inherent Rigid Vesicle with Controlled Drug Distribution
Abstract: Colloidosomes are hollow capsules whose shell is composed of closely packed uniform colloidal particles. To date, colloidosomes have been fabricated using colloidal assembly at liquid-liquid interfaces. This system also solves the problem of insolubility, instability, rapid degradation and widely used in specialized areas like protein delivery, gene delivery, targeting to brain, tumour targeting, etc. In the series of vascular systems, colloidosome is the advanced tool in drug delivery. Colloidosomes have …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 7, Issue 3, 2016 · pp. 12–25 Read article
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Ocular Films as a Drug Delivery System Against Fungal Infections: Current Insights and Future Directions
Abstract: Fungal infections of the eye, including keratitis, endophthalmitis, and blepharitis, represent a challenging class of ocular diseases due to their potential for vision loss and the limited efficacy of existing treatments. These infections are caused by a range of pathogenic fungi, such as Aspergillus, Candida, and Fusarium species, and often require long-term therapeutic intervention. Conventional topical antifungal therapies, such as eye drops and ointments, suffer from poor ocular bioavailability due …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 101–109 Read article
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Microneedles: An Innovative Drug Delivery System
Abstract: Microneedles represent a groundbreaking innovation in drug delivery systems, offering a transformative alternative to conventional hypodermic needles and transdermal patches. This advanced technology combines the precision and efficacy of needle-based delivery with the convenience and pain-free nature of patches, creating a minimally invasive platform that addresses many limitations of traditional drug administration. Microneedles are designed to penetrate the stratum corneum – the skin’s outermost layer – without reaching pain-sensitive nerves …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 60–67 Read article
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Synthesis, Characterization, and Biomedical Applications of a Silver Nanoparticle-Coated Chitosan–Fucoidan–Polymer Nanocomposite Loaded with Persea americana Leaf Extract
Abstract: Consuming a natural composite of Persea americana (Avocado) leaf extract and a chitosan and fucoidan form a biodegradable biopolymer matrix–polymer nanocomposite with biomedical applications, this study explored a potential therapeutic method. GC–MS and UV spectroscopy were used to describe the aqueous leaf extract, which was verified by phytochemical screening to contain flavonoids, tannins, phenols, terpenoids, and alkaloids. The chitosan–fucoidan biodegradable polymer matrix served as a biocompatible stabilizing and encapsulating carrier …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 · pp. 130–148 Read article
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Dioxin Sources, Types, Toxicity, and Removal Technologies: A Review
Abstract: This review provides a comprehensive investigation of dioxin, an endocrine-disrupting compound, and its impacts on environment and human health. Dioxin have antagonistic effects on hormones. It is pivotal to identify the origin of dioxin exposure for the well-being of environment and human health. Hence, the sources of dioxin, its dispersion, concentrations in air, water and soil medias, and health effects are discussed in detail. Endocrine disrupting compounds are categorized into …
Published in Journal of Industrial Safety Engineering · Vol. 11, Issue 1, 2024 · pp. 11–19 Read article
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Studies on the Self-Assembly of Steroids and DNA Mediated by Naphthalene-Based Amphiphilic Block Copolymer
Abstract: Amphiphilic block copolymers have attracted considerable interest in pharmaceutical and biomedical applications, including controlled drug release, gene delivery, and biomolecular sensing. In this study, fluorescent amphiphilic block copolymers were designed to facilitate interactions with biological molecules, such as DNA and antiviral agents, enabling their behavior to be monitored through fluorescence spectroscopy. Two novel block copolymers, poly(methyl methacrylate)-b-poly(dimethylaminoethyl methacrylate-co-naphthyl methacrylate) [PMMA-b-P(DMAEMA-co-NMA)] and poly(styrene)-b-poly(tert-butyl acrylate-co-naphthyl methacrylate) [PS-b-P(t-BA-co-NMA)], were synthesized successfully via atom …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 · pp. 183–196 Read article
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Innovative 3D Printed Cell Scaffolds with Magnetized Nanocomposites for Targeted Cancer Therapy Drug Delivery
Abstract: In recent years, scaffolds have gained increasing attention in the field of tissue engineering, especially in cancer treatment. Nanocomposite scaffolds have emerged as promising candidates for delivering drugs to cancer cells. 3D printing technology has enabled the fabrication of customized scaffolds with precise pore size and complex geometries. This study explores the development of 3D printed scaffolds of nanostructured made of graphene oxide and Poly-Caprolactone (PCL) nanocomposites, which can be …
Published in Journal of Polymer & Composites · Vol. 11, Issue 3, 2023 · pp. 48–55 Read article
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Solid Lipid Nanoparticles in Medicine: Formulation, Characterization and Future prospects
Abstract: An alternative to conventional colloidal carriers such liposomes, polymeric nanoparticles, and emulsions, solid lipid nanoparticles (SLNs) were created in the early 1990s. Benefits include targeted medicine distribution, controlled drug release, and improved stability. An extensive review of the excipients utilized, the production techniques, including the membrane contractor approach, and the possible advantages and disadvantages of SLNs is given in this work. It investigates secondary stabilization techniques like freeze-drying and spray-drying, …
Published in International Journal of Membranes · Vol. 2, Issue 1, 2025 · pp. 1–15 Read article
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Integrated Dam Automation: Real-Time Monitoring and Controlling Using IoT
Abstract: Dam automation is a critical area in water resource management, especially given the rising demand for sustainable and safe water control systems. An integrated approach to dam automation involves implementing advanced sensors and monitoring systems to improve structural safety, water quality, and resource management. This paper presents a comprehensive automation model that combines crack detection, convolutional neural networks (CNNs), water level monitoring, turbidity sensing, and rainfall data to ensure real-time …
Published in Journal of Microcontroller Engineering and Applications · Vol. 12, Issue 1, 2025 · pp. 31–38 Read article
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A Comprehensive Analysis of Novel Liposomes: Categorization, Approach, Description, and Present Formulations
Abstract: Liposomes have gained attention as a promising drug delivery system, which come with the advantages of biocompatibility, ability to load hydrophilic and hydrophobic drugs, and they can function for targeted drug delivery. In this regard, this paper offers a comprehensive overview on novel liposomes, including classification, formulation strategies, detailed structures, and current pharmaceutical applications. Recent advances in liposomal drug delivery systems includes, new liposomal architectures (i.e. stealth, targeted, stimuli-responsive, hybrid …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 15–20 Read article