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1673 articles for “identification”
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Targeting PTPN22 in Arthritis: Molecular Docking and Pharmacokinetic Evaluation of Artemisia vestita Compounds
Abstract: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by inflammation of the synovial membrane, commonly resulting in swelling, pain, stiffness, and overall fatigue. Protein tyrosine phosphatase non-receptor type 22 (PTPN22) has been identified as a risk factor linked to various autoimmune diseases, including RA. In the PTPN22 gene, two missense Single nucleotide polymorphisms (SNPs) are associated with autoimmune conditions. The R620W (C1858T, rs247660) variant in exon 14 has been …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 20–31 Read article
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Molecular Docking of Arjuna Tree Phytocompounds for Ischemic Heart Disease
Abstract: Heart disease is a serious condition that can be caused by several lifestyle changes and sometimes genetic problems. The primary protein component of apolipoprotein is the LDL receptor, which indicates that a reduction in LDL levels can reduce the risk of ischemic heart disease. Apolipoprotein levels are associated with increased levels of ischemic heart disease. Using ADMET analysis, drug likelihood prediction, and molecular docking, this work attempted to find natural …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 42–52 Read article
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Biomarkers in Cancer Research: Discovery and Future Directions
Abstract: Biomarkers have transformed the study of cancer, providing critical information regarding prognosis and therapy response and promoting earlier diagnosis. This paper discusses the different parts of cancer biomarkers, starting with their description, classification, and major types, which are the groundwork for understanding their clinical role. The discussion on the development and validation process of biomarkers is then undertaken, focusing on state-of-the-art techniques and the importance of ensuring accuracy and reproducibility. …
Published in Trends in Drug Delivery · Vol. 12, Issue 1, 2025 · pp. 22–26 Read article
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Knowledge and awareness of final years dental and medical students towards management. and clinical outcomes of maxillary sinus squamous cell carcinoma 2021
Abstract: Background: - study aimed to assess dental and medical students' knowledge on managing and clinical outcomes of maxillary sinus squamous cell carcinoma, a preventable and treatable cancer, and to address delays in referral and treatment.. objective: -To assess a knowledge and awareness of management and clinical outcomes of maxillary sinus squamous cell carcinoma among final years dental students and medical students at university of Khartoum Materials and Methods: A cross-sectional …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 1, 2025 · pp. 10–17 Read article
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Detection of Phishing Website Using URL
Abstract: Phishing attacks are one of the greatest threats to online security, where fraud websites deceive users into giving out sensitive information. Traditional methods of detection, such as blacklists and heuristic-based systems, often fail in identifying newly created or sophisticated phishing websites. This study proposes an intelligent phishing website detection system using Convolutional Neural Networks (CNNs) in analyzing URLs and associated features. Using labeled URLs, the system employs such attributes such …
Published in Journal Of Network security · Vol. 13, Issue 1, 2025 · pp. 10–15 Read article
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Real-time DDoS Attack Prediction in SDN Environments Using Machine Learning
Abstract: The ever-growing reliance on sdn-based services necessitates robust security measures against Distributed Denial-of-Service (DDoS) attacks that threaten service availability. This project investigates the development of a real-time prediction system for DDoS attacks in sdn environments, leveraging the power of machine learning. The proposed system employs a Decision Tree classification algorithm implemented in Python. To ensure accurate attack identification, the system meticulously addresses data preprocessing challenges inherent in network traffic datasets. …
Published in Journal Of Network security · Vol. 13, Issue 1, 2025 · pp. 16–27 Read article
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The Issues for Introducing Green Hydro-electricity and Electric Vehicles in Transport: Energy Sector of South Asian Region
Abstract: The rapidly developing South Asian region has immense potential of amassing huge personal car population in upcoming years requiring supply of vast amount of fossil fuel whereas this region has no sizable fossil fuel reserve. This paper investigates the potential of hydro-electricity generation from Nepal and Bhutan areas of the region, electric vehicle introduction in increasing proportion for changing the course of unsustainable transport-energy trend in this region and achieving …
Published in Trends in Transport Engineering and Applications · Vol. 11, Issue 3, 2024 · pp. 1–13 Read article
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Mathematical Models of Agricultural Cycles in Tribal Astronomy
Abstract: This paper delves into the intricate connection between traditional tribal agricultural practices and astronomical observations, showcasing how indigenous communities have historically relied on celestial movements to guide essential farming activities. By observing the phases of the moon, solar cycles, and the positions of star constellations, tribes have developed precise methods for determining the optimal timing for planting, harvesting, and seasonal planning. These astronomical practices are deeply embedded in their cultural …
Published in Research & Reviews : Journal of Statistics · Vol. 13, Issue 3, 2024 Read article
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Pharma Tech: Leveraging Software for Drug Development & Clinical Research
Abstract: The pharmaceutical sector is progressively adopting software solutions to enhance the drug development process and optimize clinical research results. Drug development is a time-consuming, expensive, and intricate process that traditionally requires extensive laboratory research, preclinical testing, and several stages of clinical trials. Software tools are revolutionizing these stages by improving efficiency, minimizing errors, and speeding up timelines. During preclinical testing, predictive software tools are used to model toxicological effects and …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 11–19 Read article
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Genomic Medicine Revolutionizes Heart Care: A New Standard of Practice
Abstract: The integration of genomic and precision medicine into cardiovascular healthcare represents a transformative advancement in addressing the global burden of cardiovascular diseases (CVDs). Precision medicine leverages genomic, proteomic, and metabolomic data to provide personalized care, optimizing treatment outcomes while minimizing adverse effects. Over the past decade, extensive research has highlighted its potential to revolutionize the management of major CVDs, including myocardial infarction, hypertension, and heart failure, which significantly contribute to …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 2, 2025 · pp. 30–37 Read article
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Self-Navigating Rover for Real Time Mapping and Disaster Management
Abstract: This paper presents the development of an autonomous rover designed for mapping and object detection in challenging terrains. The rover integrates a 6-wheel rocker-bogie mechanism for enhanced mobility and stability, making it suitable for rugged and uneven environments. Key components include an Arduino Uno for control operations, a Camera module for real-time visual data capture and object detection, and a LiDAR for precise distance measurement and spatial mapping. The system …
Published in Journal of Aerospace Engineering & Technology · Vol. 15, Issue 1, 2025 · pp. 23–33 Read article
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Screening Phytocompounds of Tinospora cordifolia to Find Potential Drug Targets for Cystic Fibrosis
Abstract: This study aimed to evaluate the therapeutic potential of phytocompounds derived from Tinospora cordifolia in treating cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene that lead to severe respiratory and digestive complications. Phytocompounds were retrieved from the IMPPAT database and subjected to molecular docking simulations using PyRx to assess their binding affinity to the CFTR protein. The top-scoring compounds – sterol, magnoflorine, tembetarine, kaempferol, and …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 16–24 Read article
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Enhancing Engine Efficiency and Reducing Emissions: A Comprehensive Review of Air Calorimeter Technology
Abstract: The article talks about the idea behind this project to pre-heat the intake air that passes through the carburettor to increase a petrol engine's fuel efficiency. The vaporization of petrol in the carburettor is influenced by the humidity of the surrounding air. Therefore, vaporization can be facilitated, and full combustion can be accomplished by preheating the carburettor's incoming air for a significant amount of time. Additionally, by lowering the amount …
Published in Journal of Aerospace Engineering & Technology · Vol. 15, Issue 1, 2025 · pp. 8–13 Read article
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The Future is Smelling: Exploring the Potential of e-Nose
Abstract: The human sense of smell, a complex and often underestimated faculty, allows us to perceive the world through volatile organic compounds (VOCs). This ability to detect and differentiate between aromas, flavors, and even potential hazards has inspired the development of the electronic nose, or e-nose. More than just a novelty, e-noses are rapidly becoming sophisticated analytical tools with applications that span across numerous industries. By mimicking the biological processes of …
Published in Journal of Semiconductor Devices and Circuits · Vol. 12, Issue 1, 2025 · pp. 15–25 Read article
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Voltage Vigilance: Ensuring Balance and curbing Theft in Power Distribution Networks
Abstract: This project proposes a system for detecting electrical overload and earth faults using an Arduino Uno controller. The system uses a current sensor to identify overloads and a voltage sensor to detect earth faults. An ESP8266 module allows users to switch between the two fault detection modes. When an overload is detected, the Arduino turns off AC bulbs using a relay and sends an alert message via a GSM module. …
Published in International Journal of Advanced Control and System Engineering · Vol. 3, Issue 1, 2025 · pp. 15–21 Read article
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Milk Allergy: Significance, Detection and Management
Abstract: Milk allergy is a significant public health issue, particularly among infants and young children, with prevalence rates between 2 and 6% in early childhood, declining to 0.1–0.5% in adulthood. It is an immune-mediated adverse reaction to milk proteins, primarily involving immunoglobulin E (IgE)-mediated responses. Symptoms range from gastrointestinal distress and respiratory complications to severe anaphylaxis. The etiology of milk allergy involves genetic predisposition, environmental factors, an immature immune system, and …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 14, Issue 1, 2025 · pp. 15–19 Read article
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Enhancing Mechanical Properties by Parameter Optimization in Fiber and Particle Reinforced Composites
Abstract: This research focuses on optimizing the mechanical and thermal properties of hybrid fiber and particle-reinforced composites through systematic parameter optimization using the Taguchi method and Grey Relational Analysis (GRA). Composites were fabricated using varying fiber volume fractions (20%, 30%, and 40%), particle sizes (20 μm, 60 μm, and 100 μm), and curing temperatures (60°C, 80°C, and 100°C) in a 3-factor, 3-level experimental design. Key properties such as tensile strength, impact …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 75–85 Read article
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Design and Performance Analysis of Sustainable Hybrid Composites for Impact Absorption and Lightweight Applications.
Abstract: This study explores the mechanical and structural properties of a novel hybrid composite composed of recycled tyre rubber, ceramics, and wood. The investigation focuses on key parameters, including energy absorption, compressive and tensile strength, and density, to evaluate the composite's suitability for diverse applications. The impact energy absorption test revealed that Sample A, comprising 50% rubber, 25% ceramic, and 25% wood, exhibited the highest energy absorption capability, with an average …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 95–104 Read article
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Carbon Capture Technologies: Innovations, Challenges, and Environmental Implication
Abstract: This review work provides a comprehensive overview of carbon capture and storage (CCS) technologies, their status, and future directions. It examines various capture methods, including pre-combustion, post-combustion, oxyfuel combustion, and direct air capture, as well as emerging and hybrid technologies such as metal-organic frameworks, ionic liquids, and microencapsulation. The study discusses the limits of current technologies and attempts to point out innovations needed to ameliorate these challenges. It also explores …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 15, Issue 1, 2025 · pp. 7–18 Read article
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Artificial Intelligence Enhanced Waste Sorting and Classification System for Urban Recycling
Abstract: This study explores the potential of Artificial Intelligence (AI) and Machine Learning (ML) to enhance waste management efficiency within urban environments. Rapid urbanization has resulted in a surge of municipal waste, which current systems often struggle to manage effectively. The proposed AI-enhanced waste sorting and classification system aims to optimize waste collection routes and accurately forecast waste generation trends, thereby reducing operational costs, fuel consumption, and traffic congestion. Additionally, AI-driven …
Published in Current Trends in Signal Processing · Vol. 15, Issue 1, 2025 · pp. 23–32 Read article