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1147 articles for “system optimization”
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Revolutionizing Gastro-retentive Drug Delivery: Exploring Innovative Formulation Strategies and Mechanisms in Floating in Situ Gel Raft Forming System
Abstract: An in-depth exploration of the transformative shift underway in gastro-retentive drug delivery, spotlighting the utilization of Floating Drug Delivery Systems (FDDS) and specifically honing in on the innovative formulation strategies and mechanisms inherent in Floating In Situ Gel Raft Forming Systems. FDDS present a promising avenue for revolutionizing drug delivery efficacy by capitalizing on buoyancy to float atop the gastric fluid surface, thereby extending gastric residence time and improving drug …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 9–21 Read article
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Green and Edge-Aware Computing: Rethinking Cloud Infrastructure for Sustainability
Abstract: Cloud computing has transformed the way organizations access and manage information technology resources, providing flexible, scalable, and cost-efficient services that support today’s data-driven world. Despite these advantages, the rapid expansion of large-scale cloud infrastructures has resulted in rising energy consumption, significant heat generation, and a growing environmental footprint. This research focuses on advancing green cloud computing by examining methods that reduce power usage while maintaining high performance. Key strategies include …
Published in Journal of Computer Technology & Applications · Vol. 17, Issue 1, 2026 · pp. 17–24 Read article
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Hydrolysis-Driven Optimization of Hydroxypropyl Maize Starch for Improved Micro-Pellet Binding and Quick Solubility of Spirulina-Based Micro-Pellets
Abstract: Acid hydrolysis is a well-established approach for modifying the physicochemical properties of polysaccharides & macromolecules including hydroxypropyl Maize starch (HPMS). In this study, the effect of varying concentrations of hydrochloric acid on the partial hydrolytic degradation of HPMS (Lycoat RS-780) was investigated at 85°C for 4 h, yielding polymers of different molecular weights. The Acid-mediated degradation effects on polymer characteristics were systematically assessed using capillary viscometry and gel permeation chromatography …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 3, 2026 Read article
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Mechanical Characterization and Machinability Optimization of Stir-Cast Al6061–SiC Metal Matrix Composites
Abstract: This study presents the fabrication, mechanical characterization, metallurgical analysis, and machinability optimization of Aluminum 6061 reinforced with Silicon Carbide (SiC) metal matrix composites (MMCs) at three weight fractions: 5%, 7.5%, and 10%. Composites were manufactured using the stir casting technique, followed by comprehensive mechanical testing (tensile, hardness, and impact), optical microscopy, and scanning electron microscopy (SEM). Machinability was assessed through turning experiments on a lathe using an L9 Taguchi orthogonal …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 Read article
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Self-Healing Structural Polymer Composites Incorporating Bio-Inspired Nanofillers
Abstract: Self-healing polymer composites become an attractive family of intelligent materials that are capable of autonomously repairing damage, which will enhance their durability, reliability and service life in extreme engineering applications. The materials are based on the principles of nature, using the nanofillers that are derived from biological systems to improve mechanical properties and self-healing capabilities by utilizing hierarchical structures and multifunctional interface interactions. The recent developments on the formulation of …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Enhancement of the Life of Helical Spring Systems
Abstract: Helical springs are essential mechanical factors considerably employed in automotive, aerospace, and artificial systems because of their capability to store and release energy, absorb shock, and sustain repeated weight cycles. The performance, responsibility, and durability of these springs play a vital part in ensuring the effectiveness and safety of the entire system in which they are integrated. Over time, numerous researchers have focused on strategies to enhance the service life …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 12–24 Read article
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Redefining Herd Health: No-Antibiotic Strategies for Revolutionizing Sustainable Dairy Development
Abstract: This study investigates the potential of no-antibiotic strategies to transform herd health management andpromote sustainable dairy development. Rising concerns over antimicrobial resistance (AMR) and the environmental consequences of antibiotic use have intensified the demand for alternative, sustainable disease management approaches. No-antibiotic strategies emphasize preventive health measures, biosecurity, and holistic practices, including optimized nutrition, vaccination, and natural antimicrobial alternatives. The study evaluates diverse management interventions, such as precision livestock farming, genetic …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 Read article
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The Contribution of A. I. in Pharmaceutical Software
Abstract: The integration of Artificial Intelligence (AI) in pharmaceutical software has significantly transformed drug development, regulatory processes, and clinical management. AI-powered tools are revolutionizing data analysis, predictive modeling, and decision-making, enhancing the efficiency and accuracy of drug discovery and development. This article explores the multifaceted contributions of AI to pharmaceutical software, including its applications in drug screening, personalized medicine, clinical trial optimization, and regulatory compliance. Additionally, we examine how AI is …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 1, 2025 · pp. 1–10 Read article
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Role of Fluid Engineering in Biomedical and Healthcare Systems: A Comprehensive Review
Abstract: Fluid engineering — the study and application of fluid behavior, transport, and interaction — has become a cornerstone of modern biomedical and healthcare systems. This review synthesizes the multifaceted roles fluid engineering plays across diagnostics, therapeutics, biomedical devices, and physiological modeling. Micro-fluidics enables precise manipulation of microliter and nanoliter volumes, facilitating rapid point-of-care diagnostics, high-throughput screening, and the fabrication of uniform nano particles for targeted drug delivery. In cardiovascular medicine, …
Published in Trends in Mechanical Engineering & Technology · Vol. 16, Issue 1, 2026 · pp. 1–5 Read article
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Advanced Design, Modeling and Optimization Techniques in Electric Vehicle Using Green Energy: A Review
Abstract: In today’s world, we are using conventional energy sources in a larger amount. To reduce it we must move to use an alternative source, it means replacing the diesel and petrol vehicles with an electric vehicle, which is the best option. The rapid expansion of electric vehicles (EVs) is expected to make them a major contributor to transportation. Increasing fossil fuel use has resulted in greenhouse gas emissions that are …
Published in Journal of Nuclear Engineering & Technology · Vol. 14, Issue 3, 2024 · pp. 20–28 Read article
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Computational Biomodeling: Transforming Drug Design with Advanced Simulations
Abstract: Computational biomodeling has emerged as a transformative approach in the field of drug discovery, significantly enhancing the efficiency and precision of identifying and optimizing potential drug candidates. This article explores the various computational techniques utilized in drug design, including molecular docking, molecular dynamics (MD) simulations, free energy calculations, and virtual screening, and examines how these methods collectively contribute to the drug development process. The integration of these advanced simulations allows …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 3, 2024 · pp. 24–29 Read article
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Integration of Semi-Interpenetrating Polymer Networks and Quantum Dot–Polymer Nanocomposites for Low-Cost, Flexible OLED Display
Abstract: Flexible OLED displays need advanced material systems to integrate capabilities for mechanical flexibility as well as thermal stability and environmental durability at low costs. Semi-interpenetrating polymer networks (SIPNs) combined with quantum dot (QD)-polymer nanocomposites serve to improve OLED performance capabilities. They combine a stable structural design along with a flexible matrix through the matrix capabilities of SIPNs which result in efficient luminescence and pure color output courtesy of CdSe/ZnS QDs …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 919–932 Read article
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Finite Element Analysis of Spur Gear Manufactured of Al7475-SiC Composites
Abstract: The spur gear is used in power transmission systems in industrial and automotive sectors. But sometimes, these gears have problems with their teeth due to excessive stress and wear. Some gears don't work as well, so in the present work better material is used to make them work well. Composite materials, which is known for their optimal strength-to-weight ratio and weight reduction benefits. So, these materials are considered substitutes for …
Published in Journal of Polymer & Composites · Vol. 12, Issue 2, 2024 · pp. 279–284 Read article
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Catalyst: Free Synthesis of Bioactive Molecules via Green Chemical Principles
Abstract: This study explores the catalyst-free synthesis of bioactive molecules, emphasizing the application of green chemical principles. Traditional synthetic methods often rely on hazardous reagents, solvents, and metal catalysts, which can pose significant environmental and health risks. In contrast, the catalyst-free approach leverages benign reaction conditions, such as solvent-free systems, ambient temperature, and pressure, to achieve efficient and selective transformations. We present a comprehensive investigation into various bioactive molecule syntheses, including …
Published in Journal of Catalyst & Catalysis · Vol. 11, Issue 1, 2024 · pp. 17–21 Read article
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Enhancing Credit Card Fraud Detection Using Device Fingerprinting and Behavioral Biometrics
Abstract: Credit card fraud is a growing global concern, with financial losses projected to reach $ 43.47 billion by 2028. Credit card fraud poses a major challenge in the financial industry, resulting in substantial financial losses and security risks. This research introduces a Machine Learning-based Credit Card Fraud Detection System designed to improve the accuracy of fraud identification. Due to the imbalanced nature of fraud datasets, SMOTE (Synthetic Minority Over-sampling Technique) …
Published in Journal Of Network security · Vol. 13, Issue 2, 2025 · pp. 40–50 Read article
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From Differential Equations to Data Science: A Survey on Analytical Methods in Contemporary Problems
Abstract: The integration of differential equations and data science methods represents a dynamic and evolving approach to solving contemporary challenges across a wide range of disciplines, including engineering, physics, biology, economics, and finance. Differential equations have long served as fundamental tools for modeling continuous systems and processes, offering powerful insights into the behavior of natural and man-made phenomena. For example, they describe how heat diffuses through materials, how populations grow in …
Published in Recent Trends in Mathematics · Vol. 2, Issue 2, 2025 · pp. 1–6 Read article
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Accelerating Unsupervised Feature Learning: Parallelized Training of Denoising Autoencoders
Abstract: Unsupervised representation learning has become a cornerstone of contemporary machine learning, enabling algorithms to extract informative features from un-labelled, high-dimensional data. This work investigates the efficacy of stacked denoising autoencoders (SDAEs) trained via parallelized stochastic gradient descent (SGD) as a scalable approach to feature extraction. By strategically leveraging multi-threaded computation, our study systematically examines the trade-offs between increased parallelism, training efficiency, and the preservation of model accuracy. Experiments on the …
Published in Journal of Image Processing & Pattern Recognition Progress · Vol. 12, Issue 3, 2025 · pp. 56–64 Read article
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Enhancement of Mechanical Properties in Eutectic Al-Si Alloy Matrix Composites Reinforced with Kyanite and Graphite via Stir Casting
Abstract: The purpose of this work is to enhance the mechanical performance of a eutectic Al–Si alloy by incorporating hard ceramic (kyanite) and soft solid lubricant (graphite) reinforcements using a liquid-state stir casting route. Metal matrix composites were fabricated with kyanite contents of 2, 4, and 6 wt.% and a constant 2.5 wt.% graphite. Their microstructures and mechanical properties were systematically evaluated. The microstructure was examined using optical microscopy and energy …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 90–100 Read article
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Effect of Skin Barrier Damage on Absorption and Action of Cosmeceuticals
Abstract: The skin acts as a primary defensive barrier protecting the human body against environmental aggressors, microbial invasion, and chemical exposure. The integrity of the skin barrier, particularly the stratum corneum, plays a crucial role in regulating the permeation of substances applied topically. Cosmeceuticals, a hybrid category between cosmetics and pharmaceuticals, are designed to deliver biologically active ingredients into the skin to exert therapeutic or beneficial effects. However, the condition of …
Published in Recent Trends in Cosmetics · Vol. 3, Issue 2, 2026 · pp. 1–19 Read article
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Computer Aided Drug Designing for Targeted Drug Delivery Systems
Abstract: The discovery and development of a contemporary sedate is widely acknowledged as an extremely difficult task that requires significant resources and effort. Therefore, computer-aided medication design techniques are widely utilized today to increase the productivity of the drug discovery and development process. Among structure-based and ligand-based drug design approaches, both recognized for their efficiency in drug discovery and development, various CADD (Computer-Aided Drug Design) techniques are evaluated based on specific …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 34–41 Read article