Search
1680 articles for “BCS Class II/IV drugs”
Nothing matched all of your words, so these match any of them.
-
Design and Assessment of Fixed Dose Combination Containing Fenofibrate and Pravastatin Sodium in Tablet Formulation: A Bioinformatics Approach
Abstract: The aim of this is study is to formulate and evaluate fixed dose combination of Fenofibrate and Pravastatin sodium in tablet dosage for the treatment of Dyslipidemia. For the formulation and optimization of fenofibrate layer, two factor three level factorial design was used as experimental design for optimization with a minimum of nine run. All the nine trial (F1–F9) has been formulated according to the experimental design by wet granulation …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 1, 2024 · pp. 1–20 Read article
-
IoT Based Pill Dispenser System
Abstract: Real-time data collection and patient database recording have been facilitated by the Internet of Things. One of the most common reasons a treatment plan does not work for a patient is that the drug is not taken at the prescribed time. People 50 years of age and beyond are more likely to suffer from diabetes, high blood pressure, Alzheimer's disease, Parkinson's disease, and other illnesses. For a patient like this, …
Published in Journal of Microelectronics and Solid State Devices · Vol. 11, Issue 1, 2024 · pp. 18–24 Read article
-
Implementing Quality by Design (QbD): Strategies, Challenges, and Best Practices across Industries
Abstract: The present comprehensive review investigated the dynamic landscape of quality standards within the pharmaceutical sector, with a primary focus on the implementation and impact of Quality by Design principles. It illuminated the multifaceted challenges encountered by pharmaceutical companies in upholding stringent quality standards amidst evolving regulatory requirements and complex manufacturing processes. By embracing Quality by Design principles, the industry aims to foster a proactive and systematic approach to product development …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 28–36 Read article
-
Change Detection in Aerial Imagery
Abstract: The development of the Multi U-Net engineering marks an essential headway in geospatial question location inside ethereal symbolism investigation. The altered U-Net addresses the complexities of multi-class division in assorted geospatial settings. Leveraging the inalienable growing and contracting pathways inside U-Net plans, the Multi U-Net exceeds expectations in capturing complicated spatial data, in this manner setting up a vigorous establishment for exact division. The extend envelops an advanced picture handling …
Published in Journal of Image Processing & Pattern Recognition Progress · Vol. 11, Issue 2, 2024 · pp. 22–28 Read article
-
Sentiment Analysis of X (Formerly Twitter) Using Machine Learning
Abstract: Sentiment analysis is a methodology to determine the nature and behavior of each and every user for the content posted on the social media platform in the form of post and feed. Consumers of the online platform are encouraged to post reviews of the product that they purchase. Little attempt is created by Amazon to confine or limit the content of these reviews. The number of reviews for various merchandise …
Published in Journal of Software Engineering Tools & Technology Trends · Vol. 11, Issue 2, 2024 · pp. 28–37 Read article
-
Automated Plant Disease Detection and Treatment Advisor Using Artificial Intelligence
Abstract: Automated plant disease detection and treatment advisors using artificial intelligence represent a significant advancement in modern agriculture. The identification of plant leaf diseases is essential to maintaining food security and agricultural output. Machine learning models, particularly deep learning algorithms like convolutional neural networks (CNNs), are trained on labeled datasets containing images of healthy and diseased plants. These models learn to classify images into different disease categories with high accuracy. Convolutional …
Published in International Journal of Cheminformatics · Vol. 1, Issue 2, 2023 · pp. 1–7 Read article
-
Effect of Vamanadhauti Along with Diet and Lifestyle Modification as per Ayurveda in Ajeerna w.s.r. Dyspepsia–A Case Study
Abstract: Introduction: In present era, Ajeerna is a very common health issue and has resemblance with dyspepsia. Ajeerna denotes improper functioning of Agni leading to lots of other diseases. Unhealthy & sedentary lifestyle, increasing intake of fast food and faulty eating habits play important role in pathogenesis of Ajeerna. In the context of Ajeerna, Sadyovamana Chikitsa is described which can be correlated with a Yogic cleansing procedure-Vamanadhauti. Vamanadhauti mainly acts on …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 2, 2024 · pp. 24–35 Read article
-
Bioconjugates and Biohybrid Polymers: Intricate Cellular Integration Methods and Sophisticated Biofunctionalization Techniques for Tailored Properties in Medical Contexts
Abstract: Bioconjugates are made when biological molecules are covalently linked to manufactured polymers. They can be used in many ways for imaging, diagnosis, and specific drug delivery. Getting perfect cellular fusion is very important for how well they work. Biomolecules can be attached to polymer scaffolds in a controlled way using techniques like click chemistry and site-specific conjugation. This makes sure that the molecules connect optimally with their biological targets. Using …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 227–243 Read article
-
Advancements in Phishing Detection: Automated Systems in Real-World Scenarios
Abstract: The goal of the abstract is to offer an automated method that uses login URLs to identify real-world scenarios. Phishing is a type of cyberattack that involves social engineering, when malefactors trick victims into providing their login credentials via a login form that sends the information to a hostile site. In this research, we offer a system that uses URL analysis to detect phishing websites by comparing machine learning and …
Published in Journal of Telecommunication, Switching Systems and Networks · Vol. 11, Issue 2, 2024 · pp. 12–17 Read article
-
Synthesis, Characterization and Evaluation of Pyridine derivatives
Abstract: Schiff bases, a class of organic compounds, have garnered significant attention due to their diverse applications in various fields such as pharmaceuticals, materials science, and coordination chemistry. This study provides a comprehensive overview of the synthesis of Schiff bases amino pyridine derivatives and aromatic ketones along with their anti-microbial activity. Method: The synthesis of Schiff bases primarily involves the condensation reaction between a primary amine and a carbonyl compound (ketone) …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 35–48 Read article
-
Advancements in Intrusion Detection: Tackling Imbalanced Network Traffic with Machine Learning and Deep Learning Techniques
Abstract: Malicious cyberattacks can frequently hide enormous amounts of typical data in unbalanced network traffic. It is very stealthy and obfuscating in cyberspace, which makes it challenging for Network Intrusion Detection Systems (NIDS) to guarantee the precision and promptness of detection. This essay investigates. Machine learning and deep learning are utilized for intrusion detection in imbalanced network traffic. It offers a novel method for addressing the problem of class imbalance termed …
Published in Recent Trends in Electronics Communication Systems · Vol. 11, Issue 2, 2024 · pp. 18–24 Read article
-
Avian Echoes: Convolutional Neural Network for Bird Vocalization Detection
Abstract: Bird species identification is a complex task within ornithology that demands advanced technological solutions. This research presents an approach leveraging Convolutional Neural Networks (CNNs) for bird species recognition based on identification of bird sound, each employing unique datasets and methodologies. The objective involves a two-stage identification process, beginning with the construction of an ideal dataset. The crucial step involves converting 1D audio waveforms to 2D spectrograms, enhancing CNNs' ability to …
Published in Journal of Aerospace Engineering & Technology · Vol. 14, Issue 2, 2024 · pp. 26–37 Read article
-
Understanding the Impact: Adult BCG Vaccination in the Fight Against Tuberculosis
Abstract: Tuberculosis (TB) remains a big global health challenge, with significant mortality rates, especially in developing nations. India holds most TB cases throughout the globe. As HIV rates, multidrug-resistant tuberculosis (MDR-TB), and extensively drug-resistant tuberculosis (XDR-TB) continue to increase, the situation is deteriorating. These all come in the way of the End TB epidemic campaign by the World Health Organization (WHO) by 2030. Immunology and vaccinology represent critical fronts in TB …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 · pp. 1–6 Read article
-
Open AI Chat GPT in Educational System: Evaluating the Efficacy of AI driven Learning
Abstract: This research delves into the effects of implementing OpenAI ChatGPT into educational systems and how it affects the results of student learning. The cutting-edge natural language processing model known as OpenAI ChatGPT has the ability to provide adaptive and individualized learning experiences, which might completely transform conventional teaching approaches. The purpose of this research is to determine if ChatGPT is more effective than more conventional approaches in enhancing students' interest, …
Published in Journal of Instrumentation Technology & Innovations · Vol. 14, Issue 2, 2024 Read article
-
Higher Order Sliding Controller Parameter Determining Method: A Research
Abstract: In this paper, it is generally believed that sliding switching surfaces should reflect the design parameters of the system in variable structure control, and the control characteristics are the way to constrain the state on sliding switching surfaces. In the literature, classical sliding (primary sliding) is considered that sliding-switching surface is the same as the characteristic equation of the closed-loop system, and the design of the control system is reflected …
Published in Trends in Electrical Engineering · Vol. 14, Issue 2, 2024 · pp. 51–66 Read article
-
Role of Neuropeptides in the Treatment of Major Depression Disorder: The Recent Updates
Abstract: Revelation of the part of neuropeptides as signaling atoms within the nervous system raised trust within the pharmaceutical field approximately 25. long time back Many neuropeptides, especially CRH, AVP, and substance P . whose receptors are presently focused on by little atoms to diminish side effects of discouragement and uneasiness, shows up to be related to the improvement and movement of temperament disarranges trouble. Neurotrophins, not exactly neuropeptides, may also …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 1–12 Read article
-
Design and Implementation of a Smart Healthcare Communication Bot
Abstract: Healthcare has proved to be one of the core factors that lead us to a magnificent life. Moreover, going to a professional for every small health issue is complicated and difficult task. To aid users with health issues, this paper describes the creation and deployment of a multifunctional healthcare assistance application. The application encompasses: The first task of the application involves a chatbot interface that gives in- depth drug information …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 2, Issue 1, 2024 · pp. 14–20 Read article
-
Artificial Intelligence Based Portable Robot Device for Autonomous Venepuncture
Abstract: Venepuncture is a source of medical hurt and is necessary for a wide range of therapeutic procedures. Venpuncture-related complications worsen in difficult settings, where the success rate is largely dependent on the physiology of the patient and the skill of the practitioner. It is difficult to find the vein for infants, adolescent girls, obese and elderly people and it is causing severe pain in the traditional manual blood drawing system. …
Published in International Journal of Advanced Robotics and Automation Technology · Vol. 2, Issue 1, 2024 · pp. 35–38 Read article
-
Multitarget Molecular Docking Using Curcuma longa Phytocompounds for Polycystic Ovary Syndrome Treatment
Abstract: Objective: The primary goal of this research is to understand and describe specific aspects of molecular interaction, it includes studying various aspects such as binding affinity, binding mode, and stability of the ligand-protein complex. Molecular docking is a computational technique used to predict the preferred orientation of one molecule to a second when bound together to form a stable complex. In this study, molecular docking will be employed to stimulate …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 15–28 Read article
-
Heterocyclic Substituted Flavones: Bridging Natural Products and Medicinal Chemistry
Abstract: Heterocyclic substituted flavones represent a unique and promising class of flavonoid derivatives, gaining significant attention in recent years due to their diverse and enhanced biological activities. These compounds are characterized by the incorporation of heterocyclic moieties such as quinoline, pyridine, thiazole, imidazole, oxazole, and pyrazole into the flavone structure, which significantly alters and often enhances their bioactive properties. This structural modification has made heterocyclic flavones particularly appealing as candidates for …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 23–30 Read article