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314 articles for “toxic”
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Exploring The Therapeutical Potential Of Pongamia Pinnata For Herpes Simplex Virus Type 1 (HSV-1)
Abstract: Objective: Pongamia pinnata (L.), commonly known as Indian beech or pongam tree, is a tropical plant renowned for its medicinal properties in traditional medicine systems. Extracts derived from various parts of Pongamia pinnata have demonstrated antimicrobial, anti-inflammatory, and immunomodulatory activities. Such attributes make it a compelling candidate for exploring its therapeutic potential against HSV infections. Thymidine kinase is the target protein mostly used in the treatment of HSV1 infections. In …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 1, 2025 · pp. 1–9 Read article
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Origin and Development of Forensic Science and Branches of Forensic Science
Abstract: Forensic science is like the Sherlock Holmes of the real world, blending scientific expertise, legal acumen, and investigative prowess to crack cases and bring justice to the forefront. It’s essentially the art of using scientific methods to untangle the mysteries of crimes and legal disputes. Picture this: a team of experts delving into the minutiae of evidence – from DNA samples to fingerprints, from chemical analyses to digital footprints – …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 15, Issue 1, 2025 · pp. 19–27 Read article
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Desk Research on Pollutants for Ecofriendly Environmental Researchers
Abstract: Substances of foreign origin called pollutants, play a main part in alarming health hazards. The essentiality of water is being used without considering the dreadful contaminants. Arsenic, the most potential and dreadful element, is always ignored whenever there is a need for the purification of water for drinking. Rehabilitation of any affected area in view of health issues is highly mandatory as per the international provisions of Environmental legislation. In …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 2, Issue 2, 2024 · pp. 14–27 Read article
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Phytopharmacognostic Study Development And Assessment Of Datura Stramonium
Abstract: Daturastrontium, a member of the Solanaceae family, is widely known for its medicinal and toxicological significance. Native to Asia and the Americas, it has been utilized for both spiritual rituals and traditional medicine due to its potent psychoactive and narcotic properties. Historically, it has been employed to treat conditions such as asthma, rheumatism, and inflammation, but its misuse, especially in religious contexts and recreationally, often leads to toxic effects like …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 2, 2025 · pp. 33–39 Read article
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Determination and Study of The Effect of High Concentrations from Heavy Metals in Environmental Samples
Abstract: This study focused on determining the concentrations of heavy metal ions to assess the environmental pollution levels of five T stations. Based on this, five samples were collected from different environments in Najaf Governorate, and the levels of heavy metal pollution were compared with the permissible values set by the World Health Organization. The research study concerned measurements of the increase and decrease in the concentration of elements and minerals …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 2, 2025 · pp. 77–84 Read article
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In Silico Screening of Terminalia chebula Phytocompounds as Potential Inhibitors of NTCP and DDB1 in Hepatitis B Virus Infection
Abstract: Hepatitis B virus (HBV) infection is a major global health concern, and chronic carriers are at risk of developing cirrhosis, hepatocellular carcinoma (HCC), and even death. Existing treatments can effectively inhibit viral replication, but they achieve little eradication of the virus because of covalently closed circular DNA (cccDNA) retention. In this investigation, bioactive compounds of Terminalia chebula, a plant known for its hepatoprotective and antiviral properties in traditional medicine, were …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 1, 2026 · pp. 33–44 Read article
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Azepines, Chemistry, Synthesis and Reactions
Abstract: Azepines, which consist of a seven-membered cyclic compound featuring six carbon atoms, an additional nitrogen atom, and no double bonds between carbons, form a diverse group within organic chemistry. The fully hydrated form of this compound is called azepam (C6H13N). Compounds and their variants play crucial roles in pharmaceutical research due to their biologic attributes like cancer-fighting, bacteria-killing, fungus-busting, virus-suppressing, and inflammation-reducing capabilities. Various organic molecules found within nature draw …
Published in International Journal of Minerals · Vol. 2, Issue 2, 2025 · pp. 35–45 Read article
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Muscle vs. Heart: A Comprehensive Review of Anabolic Steroid-Induced Cardiovascular Risks
Abstract: Anabolic-androgenic steroids (AAS) are widely used by athletes and bodybuilders to enhance muscle mass and performance. However, their misuse is associated with serious and often underrecognized cardiovascular risks. Despite their popularity, particularly among young adults, the long-term consequences of AAS abuse on cardiovascular health remain insufficiently explored in the literature. This review aims to: 1. Analyze the cardiovascular implications of AAS use. 2. Elucidate the molecular and physiological mechanisms contributing …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 2, 2026 Read article
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A Research on the Additives and Regulatory Requirements for Pediatric Formulation
Abstract: These days, pediatric considerations are incorporated early on in the creation of new medications. The guidelines and policies of European drug regulatory bodies served as the foundation for our investigation. The review comprehensively outlines excipients commonly found in pediatric medicine formulations. It identifies potentially harmful compounds flagged by scientific literature, stressing the necessity of rigorous safety checks, often involving toxicity studies. Excipients included in pediatric databases, like the STEP database, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 1, 2024 · pp. 28–45 Read article
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Extraction of Copper from Electronic Waste (E-Waste): A Review
Abstract: The issue of electronic waste, or e-waste, is indeed a significant global concern with far-reaching environmental and health implications. As technology continues to advance and become more integrated into our daily lives, the disposal of obsolete or broken electronic devices has become a pressing issue. This waste not only contains valuable metals but also toxic substances, posing significant challenges for disposal and management. Improper disposal of e-waste is a significant …
Published in Journal of Materials & Metallurgical Engineering · Vol. 14, Issue 1, 2024 · pp. 14–27 Read article
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Green Solvents in Synthesis of Schiff’s Base: A Comprehensive Review of Sustainable Approach
Abstract: The synthesis of Schiffs & bases is a fundamental process of organic synthesis that traditionally involves using hazardous organic solvents. These solvents pose significant risks to both the environment and human health due to their toxicity, volatility, and persistence in nature. These negative effects of organic solvents have led to the development of greener and more sustainable alternatives that aligns with the principles of Green Chemistry. This review paper aims …
Published in Emerging Trends in Chemical Engineering · Vol. 11, Issue 3, 2024 · pp. 30–40 Read article
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Silver Nanoparticles Loaded Polyurethane Composites for Antibacterial Medical devices
Abstract: Polyurethane (PU) polymer is widely used in biomedical application. In our study we have combined polyurethane with silver nanoparticles to develop a nanocomposite material for antibacterial medical applications. Such combination has antibacterial properties and control the toxicity too. In current research we have mixed the different sizes and types of silver nanoparticles into the polyurethane matrix. The result was their antibacterial activity, mechanical strength, and biocompatibility. The antibacterial performance of …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Photochemical Detoxification of Arsenic- and Mercury-Contaminated Soils: Geochemical Mechanisms and Pathways
Abstract: This study evaluates the geochemical aspects of soil detoxification in areas contaminated with arsenic (As) and mercury (Hg), emphasizing sustainable strategies for improving soil health and ensuring safe crop production. The research provides an ecological and toxicological assessment of regional soils and classifies them base on the concentration and mobility of toxic elements. Although the current levels of As and Hg do not yet present a critical risk to agricultural …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 06–10 Read article
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Pharmacoinformatic Based Screening Of Phytocompound Epigallocatechin Gallate To Identify As A Potential Bcl-2 Inhibitor
Abstract: Objectives: The B-cell lymphoma-2 (Bcl-2) is a protein that is particularly though to be involved in preventing apoptosis. Bcl-2 family members also essential for cancer survival, and its over expression has been linked to tumor genesis, development and resistance to anticancer treatments. The Bcl-2 family of members that inhibit apoptosis is a promising target for the creation of anticancer drugs. Methods: The study was based on computational approach using different …
Published in International Journal of Bioinformatics and Computational Biology Read article
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In Silico Docking Analysis to Identify Therapeutic Benzoic Acid Derivatives for Acute Myeloid Leukaemia
Abstract: Background: The study is anchored to initiate subjugation against modern cancer therapy for Acute Myeloid Leukaemia (AML) which involves natural therapeutics as an alternative therapy that would degrade the prospect of adverse side effects along with anti-cancer properties. Objectives: Collate the various characteristics of Giltertinib with natural benzoic acid derivative phytochemicals for a disquisition regarding their similarities and differences in the context of providing adverse side effects. Methods: ADME toxicity …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 50–63 Read article
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Urban Eye: Manhole Surveillance with IoT
Abstract: Every nation hopes to implement the idea of the "smart city" on its own. Many different issues must be resolved in order to grow the seed into a large tree. The drainage system is one of them, and it is essential. With the right drainage system, even a tiny region can make a significant contribution to society. A sewer system can be accessed through manholes. Manholes are the best approach …
Published in International Journal of Machine Systems and Manufacturing Technology · Vol. 1, Issue 1, 2023 · pp. 13–22 Read article
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Evaluation of the anti diabetic effects of ethanolic root extract from polyalthania longifora in diabetic rats induced by streptozotin and nicotinamide with considaertion of toxocological aspects
Abstract: The root of Polialthia Longifolia was selected for the evaluation of antidiabetic potential in STZ-nicotinamide induced diabetic rat model.The root extract was extracted by hot percolation using ethanol as a solvent in soxhlet apparatus and the preliminary phytochemical screening was performed and it shows that the ethanolic root extract of Polialthia Longifolia contains alkaloids, glycosides, flavonoids and tannins. Safety profile is essential for the drugs obtained from the plant origin. …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 37–50 Read article
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Strategies in the Delivery of Nonsteroidal Antiinflammatory Drugs
Abstract: Non-steroidal anti-inflammatory drugs [NSAIDs]. are widely used for the management of pain, inflammation, and fever. However, their effectiveness is often limited by gastrointestinal side effects such as ulceration and bleeding, as well as systemic complications including renal toxicity and cardiovascular risks. To address these challenges, various strategies have been developed to improve the delivery of NSAIDs, aiming to enhance their therapeutic efficacy while minimizing adverse effects. This abstract provides an …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 44–61 Read article
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Unveiling Nature’s Potential: In Silico Exploration and Identification of Herbal Remedies for Major Depressive Disorder Through Molecular Interaction Studies
Abstract: Major depressive disorder (MDD), a globally discussed mental health condition, has drawn significant attention because of its unique and intricate nature. This is marked by the enduring presence of negative emotions stemming from a lack of interest, diminished self-esteem, and excessive rumination. Despite the widespread availability of various antidepressant medications, their effectiveness is hindered by low response rates, prolonged treatment durations, and the prevalence of side effects, such as headaches, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 54–62 Read article
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Contribution, Limitations and Future Of Plant Growth Promoting Consortium in Sustainable Agriculture
Abstract: Current agricultural methods rely significantly on chemical fertilizers, pesticides, and other agrochemicals to enhance plant growth and combat pathogens, aiming to boost crop yields. However, the accumulation of chemical residues in the soil diminishes soil fertility considerably over a period. These accumulated chemicals gradually alter the soil's chemical composition, ultimately rendering it infertile. The high-risk conditions associated with these agricultural chemicals such as bioaccumulation, chemical toxicity and development of resistance …
Published in Research & Reviews : Journal of Botany · Vol. 13, Issue 2, 2024 · pp. 29–51 Read article