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Integrating Network Pharmacology and Molecular Docking to Assess Rutin’s Pharmacological Properties
Abstract: Objectives: In the present research, the network pharmacology process was applied to determine the underlying mechanism of the pharmacological properties of Rutin. Network pharmacology was utilized to reveal the interactions between medications and the targets of illnesses, and it is capable of completely articulating the complexity between diseases and medications. The identification of diverse drug-target interactions using network pharmacology may be utilized to discover novel medications for difficult conditions like …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 20–33 Read article
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Molecular Docking Evaluation of Cedrus deodara Secondary Metabolites as a Potent Anti-ovarian Cancer Agent
Abstract: Objective: According to the statistics for the year 2022 it was seen that cancer total cases is 14,61,427. After breast cancer, ovarian cancer is the second most frequent cancer among women. The estrogen receptor (PDB ID: 1X7E), progesterone receptor (PDB ID: 1A28), and Phosphoinositide 3-kinases (PDB ID: 4FJY) can be considered as target protein for ovarian cancer. The plant Cedrus deodara and its phytochemicals were chosen in this study to …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 77–93 Read article
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An Integrated Study to Extrapolate the Interaction of NMDAR with Potential Ligands for the Treatment of Alzheimer’s Disease Symptoms
Abstract: Objective: Alzheimer’s disease (AD) is the most common neurodegenerative disease affecting the health status of older adults especially those above the age of 60 years. As an outcome, two types of medications have been developed for the treatment of its symptoms which are acetylcholinesterase (AChE) and N-methyl-D-aspartate receptor (NMDAR) antagonist. This paper uses the computational approach to understand the interaction of NMDAR with four major phytocompounds (curcumin, L-epicatechin, ginsenosides, and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 15–27 Read article
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Pharmacological Management of Parkinson’s Disease: Current Therapies and Emerging Treatments
Abstract: Objective: Parkinson's disease, behind Alzheimer's, is the second most common neurodegenerative ailment and a major cause of neurological morbidity worldwide. Clinical diagnosis is made, and current management is limited to symptomatic treatments, with levodopa remaining the cornerstone of pharmaceutical therapy. In certain patient groups, deep brain stimulation of specific basal ganglia targets can provide significant clinical relief. There are currently no proven disease-modifying medicines in clinical use that can halt …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 1, 2023 · pp. 27–39 Read article
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Influence of Crystallization Time by Hydrothermal Synthesis of Ag NPs-Zeolite Composite
Abstract: The nanocomposites Ag NPs-zeolite involve zeolite loaded with silver nanoparticles and have been prepared by an easy one-pot hydrothermal autoclave method. Three samples of silver-bearing zeolite were prepared for 8 hours, 6 hours, and 4 hours, respectively, inside an autoclave at 100°C. A range of characterization procedures were used to examine the samples, such as x-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), UV-visible spectroscopy, and zeta potential. Results …
Published in Journal of Polymer & Composites · Vol. 11, Issue 2, 2023 · pp. 80–90 Read article
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Baggage Detection and Recognition Using Local Tri-Directional Pattern
Abstract: Nowadays, pattern-based image retrieval algorithms are gaining popularity just because of their uniqueness. There are several issues in the previously proposed systems. The proposed system resolves issues highlighted in the literature. Our proposed system is tested on two image datasets ILIDS and PETS 2006. LTDP provides good results as compared to LBP in baggage detection on two classes that either bag is present or not in an image because LTDP …
Published in International Journal of Mobile Computing Technology · Vol. 1, Issue 1, 2023 · pp. 8–17 Read article
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Effect of Chemically Treated Plant Cellulose on Mechanical, Fatigue and Fracture Toughness Behaviour of Polyester Composite
Abstract: In this research study, the effect of chemically treated plant cellulose on the mechanical, fatigue, and fracture toughness behaviour of polyester composites was investigated. Ramie plant cellulose fibers were used as the reinforcing material, and polyester resin was used as the matrix material. Three different chemical treatment processes, namely alkalization, acetylation, and etherification, were used to adapt the superficial chemistry of the fibers and advance their compatibility with the polyester …
Published in Journal of Polymer & Composites · Vol. 11, Issue 3, 2023 · pp. 21–29 Read article
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Review of Post-consumer Plastics and Pyrolysis Technology
Abstract: In both industrial and residential products, synthetic polymers are widely used. Since synthetic polymers are made from fossil fuels, they cannot decompose. disposal of plastic solid waste (PSW) has threatened the ecosystem seriously. In this article, we examine the various post-consumer PSW thermo-chemical recycling techniques. A method that has shown promise for converting PSW into valuable hydrocarbon compounds is pyrolysis. PSW has been broken down through thermal decomposition, however, value-added …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 57–62 Read article
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Assessing the Child–Parent Relationship Between Working and Non-working Mothers in a Selected Community of Bhubaneswar
Abstract: Introduction: Two categories of mothers exist: those who work outside the home, referred to as working mothers, and those who stay at home, often described as housewives. Working mothers may allocate quality time to their children, even if the amount of time is not necessarily large. On the other hand, non-working mothers not only manage household responsibilities but also provide care for their children and the entire family. Methods: A …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 27–33 Read article
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Effect of Calcination Condition and Cooling Method on Reactivity of Lime Sludge
Abstract: In this Experimental Study, Raw Lime sludge from the Paper industry was characterized by XRD and TGA techniques. Lime Sludge was calcined for a temperature range of 550–7500C for 2 h and cooled by air cooling. The effect of calcination temperature on the reactivity of resultant Sludge was investigated by various indirect and direct methods of pozzolanic activity assessment such as the Strength Activity Test(SAI), Lime reactivity test, XRD, TGA, …
Published in Journal of Polymer & Composites · Vol. 11, Issue 10, 2023 · pp. 36–48 Read article
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A Rare Case of Serous Cystadenoma Ovary with Cholesterol Granuloma in an Adult Female
Abstract: In reaction to cholesterol crystals and foreign body giant cells, cholesterol granulomas are formed. These are the results of long-term inflammation brought on by the buildup of cholesterol crystals in tissues. The middle ear and paranasal sinuses are the most often reported locales; however, the mediastinum, breast, and ovary have all been implicated in a small number of cases. Here, we report a rare instance of an accidental ovarian cholesterol …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 1, 2024 · pp. 13–17 Read article
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Assessment of Diuretic Activity of Hydroalcoholic Extract of Matricaria Chamomilla (Linn.) and Its Phytochemical Analysis with Emphasis on Toxicology
Abstract: While the traditional medicines are derived from medicinal plants, minerals and organic matter, the herbal drugs are prepared from medicinal plants only. This current research work will be very beneficial in figuring out the Matricaria chamomilla leaves extract diuretic effect by determining the ions and electrolyte excreted by the animals using ion selective channel inhibition. The phytochemical screening results revealed that the after which it was observed whether the alkaloids …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 1–10 Read article
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Enhancing the Performance of Evacuated Tube Heat Pipe Solar Collector Using CuO Nanofluid
Abstract: Renewable energy is an important component of sustainable development technologies that meet current demands without risking future generations' ability to meet their own. Due to fast expanding energy consumption and environmental concerns, many international scholars are seeking an alternate approach to fulfill future energy demand. Due to its abundance and pure nature, solar energy appears to be the most enticing option in this case. Because of their ease of use, …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 393–407 Read article
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Physicochemical Analysis of Groundwater Quality In Owerri Municipal, Imo State, Nigeria Using MATLAB and ANN Models.
Abstract: The physicochemical analysis of groundwater quality in Owerri Municipal council, Imo state, Nigeria was carried out. Fifteen water samples were randomly selected from the five villages that make up Owerri municipal council were anlayzed for physicochemical parameters using standard methods. The results from the study area showed that the temperature ranged between 26.5-28.0oC; рH ranged between 4.80-5.32. Electrical conductivity ranged between 77-166 µЅ/cm. The total dissolved solids were between 35.4-168.4mg/l; …
Published in Emerging Trends in Chemical Engineering · Vol. 11, Issue 1, 2024 Read article
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Cementing Sustainability: Utilizing Waste Foundry Sand to Enhance Concrete Performance and Reduce Environmental Impact
Abstract: The incorporation of waste foundry sand into concrete production represents an environmentally conscious and cost-effective approach. This method involves substituting discarded foundry sand for a portion of traditional fine aggregates in concrete mixtures. The primary objective is to address environmental concerns associated with waste disposal while simultaneously achieving cost efficiency in construction materials. By integrating waste foundry sand into concrete, this practice promotes sustainability by reducing landfill waste and conserving …
Published in Journal of Construction Engineering, Technology & Management · Vol. 14, Issue 1, 2024 · pp. 13–21 Read article
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Importance of inflammatory marker ratio and lipid profile ratio in Acute Ischemic Stroke
Abstract: Background: Acute Ischemic Stroke is a chronic inflammatory disease that is projected to be one of the leading causes of mortality affecting millions of people globally. It is essential to study the Platelet lymphocyte ratio (PLR), Neutrophil lymphocyte ratio (NLR) ratios and C reactive protein (CRP) in impacting the inflammatory status during stroke. It is also important that altered lipid metabolism could influence the inflammatory conditions associated with AIS. Hence …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 19–31 Read article
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An Open Labelled Parallel Arm Randomized Clinical Trial of Tuvaraka Oil Prepared By Two Different Method In The Management of Pama
Abstract: In Ayurveda, all skin diseases have classified mainly into two groups i.e., Mahakushtha (major skin diseases) and Kshudrakushtha (minor skin diseases). Tuvaraka [Hydnocarpus laurifolia (Dessnt).Sleumer] is one among the most useful drugs for the treatment of Kushtha (Various skin diseases) and Madhumeha (Diabetes Melitus). Pama is described under Kshudra Kushtha. which can be correlates with scabies. Aim: To evaluate the clinical efficacy of Tuvaraka oil prepared by modified method and …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 1, 2024 · pp. 29–36 Read article
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Effects of Soil and Water Conservation Measures on Selected Physico-Chemical Properties of Soil in Qenshiben Watershed Central Ethiopia Regional State
Abstract: One of the main causes of declining soil resources in Ethiopia has been identified as soil erosion, which in turn negatively affects the agricultural productivity of the country. In order to alleviate the problem of soil erosion, numerous soil and water conservation measures have been implemented during the past ten years in numerous parts of the country through community mass mobilization. In spite of the fact that conservation measures had …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 13, Issue 1, 2024 · pp. 23–32 Read article
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Vibration Analysis of Woven Hybrid Carbon-Kevlar Composite Laminates
Abstract: Composite materials have revolutionized the field of engineering and design, providing the ability to combine two or more materials with different properties to create new materials with enhanced characteristics. The intricate process of weaving together carbon fiber and Kevlar fiber to create a 3D composite fabric is not only fascinating but also results in a beautiful, intricate pattern. Hand weaving is an art that requires precision and skill, and when …
Published in Journal of Polymer & Composites Read article
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Dynamic Performance Enhancement of Polymer Composites through Metaheuristic machinining optimization
Abstract: This work aims to provide an optimization of meta-heuristic algorithms in order to improve the dynamic behavior of composite materials utilized in various practical engineering tasks. Based on the Comprehensive literature review it has been observed that composite sandwich panels with PVC foam cores accomplished mechanical characteristics superior than those ones that were produced on PU foam core mainly in flexural, compression, and impact tests Thus the study establishes the …
Published in Journal of Polymer & Composites · Vol. 12, Issue 2, 2024 · pp. 114–129 Read article