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118 articles for “polymer formulation”
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Ocular Films as a Drug Delivery System Against Fungal Infections: Current Insights and Future Directions
Abstract: Fungal infections of the eye, including keratitis, endophthalmitis, and blepharitis, represent a challenging class of ocular diseases due to their potential for vision loss and the limited efficacy of existing treatments. These infections are caused by a range of pathogenic fungi, such as Aspergillus, Candida, and Fusarium species, and often require long-term therapeutic intervention. Conventional topical antifungal therapies, such as eye drops and ointments, suffer from poor ocular bioavailability due …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 101–109 Read article
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Application-Driven Rule-Based Framework for Lubrication Failure Modes in Industrial Systems
Abstract: Modern lubricants increasingly rely on polymer-based composites, integrating synthetic base oils, polymer thickeners and solid additives like MoS₂ and PTFE for high-performance applications. These formulations not only enhance thermal and mechanical stability but also enable low-friction operation across diverse industrial conditions. Lubrication-related failures represent a critical cause of unplanned downtime and reduced reliability in industrial machinery. This paper presents an application-driven, rule-based framework designed to assess and mitigate lubrication failure …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 522–531 Read article
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Fabrication and Characterization of Diacerein Loaded Nanosponge for Topical Delivery
Abstract: Diacerein, an anti-inflammatory drug, which comes under BCS class II, commonly used in treatment of osteoarthritis has limited by its poor solubility and bioavailability when administered topically. This study aimed to develop and evaluate diacerein-loaded nanosponges gel using varying concentrations of ethyl cellulose and polyvinyl alcohol (PVA) to enhance its delivery. Nanosponges were prepared using an emulsion solvent evaporation technique, with different ratios of ethyl cellulose (0.05-0.250%) and PVA (0.2-0.3%). …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 26–46 Read article
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Crystallographic Studies on The Stability of Pharmaceutical Compound
Abstract: Crystallographic studies provide detailed insights into the molecular structure and intermolecular interactions within a crystal lattice, which are key determinants of a compound's stability. By analyzing crystal structures, researchers can identify potential polymorphs, solvates, and hydrates that may impact the physical and chemical stability of the drug. This knowledge helps in optimizing formulation strategies, predicting shelf life, and ensuring consistent drug performance. Advanced techniques like X-ray diffraction and neutron diffraction …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 1, 2024 · pp. 38–42 Read article
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Pharmaceutical Bead Formulations: A Comprehensive Overview into Advanced Drug Delivery
Abstract: Pharmaceutical beads are a unique and flexible drug delivery vehicle that provides numerous possibilities to control the release of drugs, protect them, and increase their therapeutic performance. These beads make it possible to design several types of therapeutic regimens by incorporating active pharmaceutical ingredients in a polymeric or lipid matrix. This review discusses the bead technology in drug delivery from its inception to its present application, focusing on the most …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 78–100 Read article
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Chitosan polymer and composites Hydrogels: An Emerging Approach for Microplastic Elimination from Water
Abstract: Hydrogel is a polymer network which can retain huge volumes of water but still retains its shape because of its special chemical formula. Recently, hydrogels have become an object of great interest for environmental remediation due to the possibility of controlling their physicochemical properties in the case of removal of microplastics. The current work reviews and analyzes the efficiency of application of conventional coagulation systems based on chitosan and new …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Prediction of Mechanical Properties for Advanced Engineering Applications utilizing Polymer Composite Materials by Machine Learning
Abstract: Polymer composites show great promise as engineering materials because of their mechanical performance, resistance to corrosion, lightweight nature, and adaptability in design. Aerospace, automotive, biomedical, maritime, and civil engineers all rely on mechanical property prediction to cut down on trial expenses, expedite product development, and optimize material selection. Speedy design optimization is not possible using traditional numerical and experimental methods due to the high costs associated with material characterisation, computational …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 Read article
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Evaluation of Polyethylene Glycol (PEG)-Based Polymers for Improving Solubility and Bioavailability of Poorly Soluble Drugs
Abstract: A significant barrier to optimizing oral bioavailability is the inadequate water solubility of numerous pharmaceutical compounds. This study examined whether polymer systems utilizing polyethylene glycol (PEG) may enhance the solubility and bioavailability of a poorly soluble model drug. Multiple PEG polymers with molecular weights between 2,000 and 10,000 Da were utilized to produce PEGylated preparations. The formulations were subsequently evaluated for dissolution efficacy, medication loading capacity, particle size, and solubility …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 489–499 Read article
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Controlled Drug Delivery of Furosemides Using Floating Tablet System
Abstract: The development of gastroretentive drug delivery systems (GRDDS) has gained interest, particularly for drugs like furosemide with narrow absorption windows in the upper gastrointestinal (GI) tract. Furosemide, a commonly used diuretic, faces challenges due to limited bioavailability and rapid elimination, requiring frequent dosing and affecting patient compliance. This review highlights the formulation and evaluation of floating furosemide tablets as an effective strategy to enhance therapeutic efficacy. Floating tablets allow prolonged …
Published in International Journal of Membranes · Vol. 2, Issue 1, 2025 · pp. 23–31 Read article
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Advances in Polymeric In Situ Drug Delivery and Soft Biosensors: Innovations in Biochemical Sensing and Personalized Healthcare
Abstract: Advanced healthcare and personalized medicine are undergoing a transformation thanks to in situ medication delivery systems and biochemical sensor technology. Polymeric in situ drug delivery systems form gels upon administration, releasing medications in a controlled manner and providing benefits such as ease of administration and enhanced patient compliance. Similarly, advancements in soft electronics, including flexible and stretchable biosensors, enable continuous, in situ biochemical monitoring, conforming to complex biological environments like …
Published in International Journal of Cheminformatics · Vol. 2, Issue 1, 2024 · pp. 27–32 Read article
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Nanoformulation Strategies: Emerging Innovations in Drug Delivery Systems
Abstract: Nanotechnology is significantly advancing the pharmaceutical industry by introducing nanosystems that improve drug delivery, therapeutic efficacy, and patient outcomes. Various nanosystems-such as liposomes, dendrimers, polymeric nanoparticles, solid lipid nanoparticles, carbon nanotubes, and metallic nanoparticles-offer benefits like enhanced bioavailability, targeted delivery, improved stability, and reduced side effects. Innovative formulation strategies, including surface functionalization, particle size optimization, and use of biodegradable carriers, support controlled and sustained drug release. Additionally, production in non-aqueous …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 54–67 Read article
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Multi-Scale Analysis of Polymer Based Energy Storage Systems for High Performance Battery Applications
Abstract: The energy storage systems based on polymers are becoming promising materials for the next generation of high performance batteries because of their excellent mechanical flexibility, improved safety, and favorable electrochemical properties. Even with computational tools in Python, polymer-based energy storage systems remain plagued by poor ionic conductivity, complicated electrochemical reactions and potential thermal runaway. Therefore, a multi-scale model is proposed to improve battery performance, thermal stability, reliability, and large-scale deployment …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 1035–1048 Read article
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Exploration of Diverse Epoxy-Based Surface Coating Methods for Enhancing Anticorrosion Characteristics
Abstract: Epoxy-based polymers, commonly referred to as polyepoxides, constitute one of the most versatile and widely adopted categories of polymeric materials due to their exceptional structural, mechanical, and chemical characteristics. Their unique macromolecular framework enables strong interfacial bonding, high mechanical stability, and superior resistance to environmental and chemical degradation, positioning them as advanced alternatives to many traditional organic corrosion inhibitors that often fail under prolonged exposure to aggressive conditions When polyepoxides …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 167–177 Read article
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Synthesis, Characterization, and Thermogravimetric Analysis of Polylactic Acid-Based Bio-Adhesive for Industrial Applications
Abstract: This study investigated the synthesis, characterization, and thermogravimetric analysis of polylactic acid (PLA)-based bio-adhesives for industrial applications. The adhesive was synthesized using an emulsion polymerization method with varying compositions of PLA and vinyl acetate. The physicochemical, mechanical, and thermal properties of the synthesized adhesives were assessed through pH analysis, viscosity measurement, peel strength evaluation, tack tests, biodegradability investigations, Fourier Transform Infrared Spectroscopy (FTIR), Differential Scanning Calorimetry (DSC), and Thermogravimetric Analysis …
Published in Journal of Materials & Metallurgical Engineering · Vol. 16, Issue 2, 2026 · pp. 39–54 Read article
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Comprehensive Evaluation of Quercetin from Bauhinia purpurea for Its Anti-Acne and Anti-Inflammatory Potential, Including Advances in Quercetin-Loaded Nanogel Formulation
Abstract: Acne vulgaris is among the most prevalent chronic inflammatory dermatoses in clinical dermatology, afflicting a substantial proportion of the global adolescent and adult population. Conventional pharmacotherapies — including topical retinoids, benzoyl peroxide, and systemic antibiotics — remain the therapeutic mainstay; however, their long-term utility is progressively undermined by adverse cutaneous reactions, systemic toxicity, and the rising prevalence of antibiotic-resistant Cutibacterium acnes strains. These limitations have intensified scientific interest in plant-derived …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 2, 2026 Read article
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Analysis of a Battery Pack Module for a Formula Student Car
Abstract: This research aims to evaluate the development of a high-voltage accumulator system that meets established standards of safety and operation. It examines key components, protocols, and techniques used in its creation while assessing performance in electronic cooling and structural integrity. Polymers, serving as electrical insulators and flame retarders, have found an interesting application in EV battery packs. This study focuses on polycarbonate materials' ability to withstand thermal and structural loads …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 320–339 Read article
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Evaluation of Mucoadhesive Polymers for Nasal Delivery of Herbal Bioactives
Abstract: A study assessed mucoadhesive polymers for intranasal herbal bioactive administration with higher residence time and mucosal permeability. Chitosan, Carbopol® 934P, and HPMC K15M were utilized to manufacture mucoadhesive nasal gels with standardized herbal bioactive fractions. Formulations were examined for pH, viscosity, spreadability, drug content, mucoadhesive strength, in-vitro release, ex-vivo penetration, and short-term stability. All formulations demonstrated a suitable pH for nasal usage and uniform drug content (97.48 ± 1.12% to …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1680–1689 Read article
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Enhancing Mechanical Performance in Reinforced Hybrid Composites using Silicon Carbide and Aluminium Oxide Fillers
Abstract: Hybrid composites are becoming useful because they have better qualities than regular composites. This study examines the conventional properties of composites that utilise SiC and Al2O3 as filler components. Kevlar, S-glass, and sisal fibers at 90° and 0°, followed by additional layers of S-glass and Kevlar. To make sure that the material qualities were the same throughout, the resin and fibre layers were arranged in an alternating pattern. Mechanical testing …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 934–945 Read article
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Recent Advances in Smart Polymer Composites for Plant Health Monitoring: A Strategic Integration of Sensing Mechanisms and Computational Intelligence
Abstract: Plant health assessment is crucial for agricultural production and food security, as plant diseases significantly affect crop yields and quality. This paper reviews the applications of polymers and composite materials in the evaluation of plant health, focusing on both natural and artificial polymers, carbon materials, and polymeric–nanoparticle composite materials. Various types of sensing principles, such as colorimetry, fluorimetry, surface plasmon resonance (SPR), surface enhanced Raman scattering (SERS), and interferometry, are …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 Read article
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Novel Poly (Methyl Cellulose-G-Acrylamide)/Sodium Alginate Based Zeolite 4A Filled Mixed Matrix Membranes for The Separation of Water-Isopropyl Alcohol Mixtures by Pervaporation
Abstract: The Filled blend matrix membranes of (Methyl Cellulose-g-Acryl amide)/Sodium Alginate {(MC-g-AAm)/NaAlg} prepared via solution casting method by in situ incorporation with 4A zeolite particles in 5, 10 and 15 mass % with respect to the weight of (MC-g-AAm)/NaAlg membrane. Several analytical tools such as scanning electron microscope (SEM), atomic force microscope (AFM), Fourier transform infrared spectroscopy (FTIR), X-ray powder diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and thermo-gravimetric analysis (TGA) were …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 131–152 Read article