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1953 articles for “phosphoinositol-3-kinase pathway” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Manufacturing Processes and 3D Printing of Health Diagnostic Tools: Economic Analysis of Open Source Frameworks
Abstract: Health diagnosis tools, for example, the incorporation of 3D printing into their manufacturing, drastically changed medical technology, providing cheap, customizable, fast tools in the field. This transformation has been accelerated by open-source frameworks that decrease dependence upon proprietary manufacturing and increase accessibility to diagnostic tools. Economic benefits of open-source 3D printing include reduced production costs, less dependence on global supply chains, and better equity of access to health care globally. …
Published in Journal of Open Source Developments · Vol. 12, Issue 1, 2025 · pp. 43–46 Read article
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Analysing the Deep Hole Drilling Characteristics of AISI 316 Alloy Using Peck Drilling Approach
Abstract: This study aims at the deep hole drilling characteristics of AISI 316 alloy utilizing the Peck drilling procedure. It is well-established that hole is the most prevalent machining process, requiring precise techniques to achieve optimal cutting conditions. AISI 316 has high corrosion resistance and mechanical features. It is widely utilized in the aerospace, vehicle, aircraft, and other industries. Due to its high modulus of elasticity, reactivity at high cutting speeds, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 14–28 Read article
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Evaluating Chassis Designs for Gesture-Driven Robots: A Study of Iron, Acrylic, and 3D Printed Solutions
Abstract: Gesture-driven robotic systems are becoming increasingly relevant in applications such as assistive technology, industrial automation, and interactive systems. The choice of chassis material plays a crucial role in determining the robot's mechanical strength, weight, and ease of fabrication. This study systematically evaluates three chassis materials—iron, acrylic, and 3D printed polymers—to determine their suitability for gesture-controlled robots. A standardized robotic configuration, including two rear motors, two front dummy axles, an L298N …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 686–692 Read article
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3D Printing and Composite Fabrication Technologies in Health Assistive Devices for Disabled Peoples: Social and Legal Fabrics
Abstract: As 3D printing and fabric technologies have become more common, the way disabled people get health care has changed. It can even print cheap, personalized devices that can be found all over the world and power themselves in just one day after doctors design them and take them. This has given people in different countries a lot more chances to help without having to leave their own country. This makes …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 624–629 Read article
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Greener 3D Printing: The Role of Artificial Intelligence in Sustainable Polymer and Composite Manufacturing
Abstract: The integration of sustainable materials with additive manufacturing (AM) technologies marks a significant step towards environmentally responsible production. Biodegradable polymers, recycled thermoplastics, and bio-based composites, when used in 3D printing, offer the potential to reduce the ecological footprint of manufacturing. However optimizing the interplay between material properties process parameters, and product performance remains a complex challenge. This review examines how artificial intelligence (AI) is being applied to address these challenges …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 288–300 Read article
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Nutrient-Mediated Activation of Cellular Signaling Pathways: Mechanistic Insights into Attenuation of Toxin Induced Inflammation in Food Animals
Abstract: Dietary and environmental toxins remain a persistent challenge in food animal production, where subclinical and clinical inflammation compromises health, productivity, and food safety. Toxin induced inflammation is driven by oxidative stress, mitochondrial dysfunction, and dysregulated immune signaling, resulting in impaired metabolic efficiency and increased disease susceptibility. Recent advances in nutritional science have revealed that nutrients act not only as substrates for growth but also as signaling molecules capable of modulating …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 1–12 Read article
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A Review on Two-Wheeled Self-Balancing Robot Using Spartan-3E FPGA for Sensor Fusion and Real-Time Motor Control
Abstract: Two-wheeled self-balancing robots (TWSBR) are a popular application of embedded control and robotics because they operate on the inverted pendulum concept, which is naturally unstable. The main objective of such robots is to continuously maintain balance by estimating the tilt angle and applying corrective motor action in real time. In most practical systems, low-cost inertial sensors such as accelerometers and gyroscopes are used for tilt measurement. However, accelerometer readings are …
Published in Journal of VLSI Design Tools and Technology · Vol. 16, Issue 1, 2026 · pp. 17–27 Read article
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In Silico Molecular Docking of Indigofera tinctoria Phytocompounds to Target EGFR/ERK and FGFR/FGF Pathway Proteins Involved in Prostate Cancer
Abstract: Objective: Prostate cancer being the second major cause of cancer-related deaths in males, affects the small walnut-shaped gland below the bladder called the prostate gland. The epidermal growth factor protein (EGFR), cascade protein (ERK), and fibroblast growth factor proteins (FGFR and FGF) are involved in the different signaling pathways that lead to the formation of different products, that are responsible for the progression of cancer and thus can be considered …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 34–56 Read article
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An Insilico Study of Isobutrin and Phosphorylase Kinase - A Ray of Hope for Psoriasis Patients – Clinical Hypothesis
Abstract: Psoriasis is a chronic, hyper-proliferative and inflammatory skin disease. Increased levels of the calmodulin-containing enzyme, namely, phosphorylase kinase (PhK), were observed in the human epidermis of the active psoriasis cases. Thus PhK is a potential biomarker for the diagnosis and progression of the skin disease, namely, psoriasis. The search for the potential molecules that could supress the over expression of PhK is underway and any break-through in this direction leads …
Published in International Journal of Cheminformatics · Vol. 2, Issue 1, 2024 · pp. 1–8 Read article
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Optimization of FDM 3D Printer Process Parameters For PETG Material Using TOPSIS Technique
Abstract: 3D printing is a quickly evolving process that builds the desired shape by layering on material. In the era of modern production, additive manufacturing has grown in significance due to its user-friendliness. By using this technique, one can produce complex & intricate geometries with much ease when compared to conventional manufacturing. With the increased demand for 3D printing, consideration towards strength quality and other mechanical properties is also increasing progressively. …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 601–609 Read article
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Green Analytical Chemistry in Pharmaceuticals: Pathways to Sustainability and Compliance
Abstract: This review paper explores the integration of green analytical chemistry (GAC) in the pharmaceutical industry as a pathway to EU compliance and environmental sustainability. The review highlights a range of studies that focus on the application of green solvents, green extraction methods, biocatalysts, and energy-efficient techniques. Key findings suggest that employ eco-friendly solvents, such as ethanol and water and methods, like ultrasound-assisted extraction (UAE) and supercritical fluid extraction (SFE), significantly …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 7–12 Read article
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Utilization of 3D Printing Techniques in the Prosthetics Manufacturing: Historical, Current, and Future
Abstract: Prosthetics for people with upper-limb differences have an intriguing and extensive history, yet problems that have not been resolved still exist. Children's prosthesis requirements are more complicated because of their rapid growing. A child's psychological development can be significantly impacted by their access to a technology. Children frequently cannot access technologies that support both cosmetic form and user function because of their high cost, insurance policies, medical availability, perceived durability, …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 3, 2025 · pp. 15–26 Read article
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In silico Molecular Docking Analysis of Stephania glabra phytocompounds Targeting Thymidylate Kinase for potential Antituberculosis Activity
Abstract: Tuberculosis (TB) is an infectious disease caused by the bacteria Mycobacterium tuberculosis. It mainly affects the lungs and spreads through the air when a person with active TB in their lungs coughs, sneezes, or spits. This study investigates several bioactive compounds derived from plants to forecast how effective plant-based ligands will be at preventing tuberculosis. The purpose of the study was to use computational techniques to assess the effectiveness of …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
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Design of Plant for the Production of 30,000 Tons Per Year Capacity of Dimethyl Carbonate (DMC) from Natural Gas Using Aspen HYSYS
Abstract: This study focuses on the design of a plant for the production of 30,000 tons per year of dimethyl carbonate (DMC) from natural gas. The plant design was carried out using the Aspen HYSYS Software. The data obtained from Kokori natural gas served as the primary feedstock for the plant. A kinetic model for the production of DMC was developed from existing literature, followed by the development of the mathematical …
Published in Emerging Trends in Chemical Engineering · Vol. 12, Issue 3, 2025 · pp. 45–60 Read article
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Using Machine Learning to Guess Photochemical Reaction Pathways
Abstract: Photochemical reactions are crucial to many activities in the fields of energy conversion, environmental cleanup, and synthetic chemistry. However, predicting their causes and results effectively is still very hard since they entail excited electronic states, nonadiabatic transitions, and complicated potential energy surfaces. Machine learning (ML) has been a powerful technique to go along with classic quantum chemistry methods in the last few years. It offers better prediction capability and lower …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 3, Issue 2, 2025 · pp. 01–12 Read article
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Interfacial and Tribo-Mechanical Performance of a TiO₂–Castor Oil Polymeric Nanofluid During Sustainable Machining of AISI 316L Stainless Steel Under MQL Conditions
Abstract: This research examines the tribo-mechanical performance and interfacial film characteristics of a TiO₂-reinforced castor-oil polymeric nanofluid during the turning of AISI 316L stainless steel under minimum-quantity lubrication (MQL). A Taguchi L9 orthogonal array was utilized to assess the synergistic effects of cutting speed, depth of cut, and coolant composition on surface integrity, while machining experiments were performed under dry, conventional, and TiO₂-nanofluid lubrication techniques. ANOVA and multiple-regression modeling were used …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 901–914 Read article
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A Review on Transforming Patient Pathways: The Impact of Pharmaceutical Software on Drug Manufacturing and Safety Monitoring
Abstract: The development, production, and safety monitoring of pharmaceuticals are being revolutionized by incorporating digital technologies. Throughout drug lifecycles, pharmaceutical software which includes cloud-based systems, automation, data analytics, and artificial intelligence (AI) has emerged behind efficiency and innovation. Real-time monitoring, predictive maintenance, and process optimization are made possible in manufacturing by software tools like Digital Twins, Manufacturing Execution Systems (MES), and Quality Management Systems (QMS). These technologies improve batch consistency, lower …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 40–46 Read article
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Integrated Surface Water–Groundwater Dynamics: Implications for Pollution Pathways, Prevention, and Environmental Control
Abstract: Water resources worldwide are increasingly threatened by pollution pressures amplified by climate change and intensified human activities. The vulnerability of surface water and groundwater systems to contamination is strongly governed by their dynamic hydrologic connectivity, which is often overlooked in pollution prevention and control frameworks. Rising global temperatures, altered precipitation regimes, land-use change, and intensified abstraction patterns modify recharge processes, flow paths, and contaminant transport mechanisms across environmental landscapes. This …
Published in International Journal of Pollution: Prevention & Control · Vol. 4, Issue 1, 2026 · pp. 34–40 Read article
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Catalyst-Driven Degradation and Failure Analysis of Intergranular Cracking in 316H Studded Pipes under Refinery Heat Recovery Conditions
Abstract: A failure analysis investigation was carried out on a high-temperature studded pipe used in a convection module for heat recovery in an oil and gas refinery application after leakage was detected during pre-commissioning hydrotesting. The investigated pipe was manufactured from AISI 316H austenitic stainless steel, and carbon steel studs had been joined to its outer surface by high-frequency resistance welding. Two leaks were reported in the pipe under investigation, and …
Published in Journal of Catalyst & Catalysis · Vol. 13, Issue 1, 2026 Read article
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Biopolymer-Based 3D Composite Scaffolds for Bone Tissue Engineering: Photothermal-Responsive Systems with Controlled Pt (IV) Prodrug Release
Abstract: Biopolymer-based composite scaffolds have attracted significant attention as multifunctional platforms at the intersection of polymer science, regenerative medicine, and cancer nanotherapy. In this study, a dual-functional scaffold was developed for simultaneous osteosarcoma treatment and bone regeneration using poly (L-lactic acid) (PLLA) reinforced with bioactive glass (BG) and integrated with a glutathione-responsive platinum (IV) prodrug system (PDA@Pt). To improve interfacial adhesion, photothermal conversion efficiency, and tumor-specific activation, the Pt (IV) prodrug …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 351–361 Read article