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76 articles for “pharmacological management”
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Pain Management Through Ayurvedic Tablets and Capsules
Abstract: Triphala Guggulu is a classical formulation widely used in Ayurveda for the management of metabolic and inflammatory disorders. It represents a synergistic combination of Triphala – composed of Emblica officinalis, Terminalia bellirica, and Terminalia chebula – along with the oleo-gum resin of Commiphora mukul. In traditional Ayurvedic practice, this formulation has been prescribed for conditions, such as arthritis, obesity, hyperlipidemia, and chronic constipation, primarily due to its reputed ability to …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 1, 2026 · pp. 23–28 Read article
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A Systematic Review on Peptic Ulcer Disease and its Pharmacological Treatment
Abstract: A chronic gastrointestinal condition known as Peptic Ulcer Disease (PUD) is typified by the formation of ulcers or mucosal erosions in the proximal duodenum and stomach. In the pathophysiology of PUD, the equilibrium between defensive processes like mucus and bicarbonate secretion, mucosal blood flow, and prostaglandin production, and aggressive factors such stomach acid secretion, pepsin activity, and Helicobacter pylori infection, is upset. Although stress and food have historically been blamed, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 76–84 Read article
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In Silico Investigation of 2,3-Dihydrobenzofuran from Centella asiatica: A Possible Pioneer in the Management of Tetanus
Abstract: Objective: Tetanus toxin (TeNT) is a neuroprotein toxin, the most toxic known. They have three functional domains and are structurally similar. They possess an N-terminal catalytic section (light chain), an internal domain for heavy-chain translocation (HN domain), and a C-terminal receptor binding domain for the heavy chain (Hc domain or RBD). Tetanus, an acute nerve-affecting disease, is provoked by a toxin-producing bacterium called Clostridium tetani. This bacterium is environmental, Gram-positive, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 19–30 Read article
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Pharmacology in Clinical and Therapeutic Settings
Abstract: Polypharmacy, which refers to the practice of taking many medications at the same time, is becoming more common among elderly populations as a result of the steadily increasing prevalence of chronic conditions. The clinical and therapeutic consequences of polypharmacy are investigated in this paper, with a particular emphasis placed on drug-drug interactions, altered pharmacokinetics, and patient safety. The physiological changes that occur with advancing age have a substantial impact on …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 51–58 Read article
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Herbal Medicines and Complementary Therapies: Their Role, Types and Applications
Abstract: Medicinal plants are used in herbal medicine to treat and prevent illnesses. This includes the use of standardized and titrated botanical extracts in addition to common and traditional medicines from different cultures. The safety of a treatment may be suggested by its long history and deep cultural roots in traditional medical systems, but this does not always imply that it is effective. This is especially important in herbal medicine, since …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 40–53 Read article
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Comprehensive Review of Kojic Acid and Its Derivatives: Biological Activities, Safety, and Therapeutic Potential in Depigmentation
Abstract: There are several uses for kojic acid in human medicine, particularly in depigmentation. Additionally, derivatives of it are suggested to enhance efficacy, avoid side effects, and stop chemical degradation. With an eye toward human use and an attempt to clarify the action mechanisms, the goal of this study was to review the most recent scientific literature regarding the biological activities and safety information of kojic acid or its derivatives. During …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 45–53 Read article
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Molecular Pharmacokinetics and Structural Docking of Phenolic Acids for Targeting NF-κB Pathway Components in Inflammation and Fibrosis: A Computational Approach Toward Therapeutic Discovery
Abstract: Inflammation and Fibrosis are critical pathological processes associated with various chronic diseases, often mediated by the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway. This study investigates the therapeutic potential of phenolic acids as modulators of the NF-κB pathway, aiming to identify novel ligands that can effectively interact with key components of this signaling cascade. A comprehensive computational approach was employed, utilizing molecular docking, pharmacological screening, and post-docking …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 14–31 Read article
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Pharmacokinetic and Pharmacodynamic Studies of Black Seed Derived Compound
Abstract: Black seed (Nigella sativa) has been celebrated for centuries for its remarkable therapeutic properties. Among its bioactive compounds, thymoquinone (TQ) has gained significant attention in pharmacological research due to its diverse health benefits. This review delves into the pharmacokinetic (PK) and pharmacodynamic (PD) properties of black seed compounds, with a particular emphasis on TQ, the most extensively studied component. The PK of TQ includes the parameters of absorption, distribution, metabolism, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 1, 2025 · pp. 36–43 Read article
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Investigating the Impact of Viral Infections on Pharmacokinetics and Pharmacodynamics of Antiviral Drugs
Abstract: The emergence and re-emergence of viral infections pose significant challenges to public health, necessitating a comprehensive understanding of how these infections impact the pharmacokinetics and pharmacodynamics of antiviral drugs. This review explores the intricate interactions between viral pathophysiology and the pharmacological effects of antiviral agents. Factors such as viral replication dynamics, host immune responses, and the genetic variability of both viruses and hosts significantly influence drug absorption, distribution, metabolism, and …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 23–30 Read article
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Electroconvulsive Therapy in the Management of Schizophrenia: A Systematic Review in Emergency Nursing Practice
Abstract: Electroconvulsive therapy (ECT) is a well-established treatment for various psychiatric disorders, including schizophrenia, particularly in cases where patients are resistant to conventional treatments. Schizophrenia, a chronic and severe psychiatric disorder, often presents with a combination of positive symptoms (such as hallucinations and delusions), negative symptoms (such as social withdrawal and emotional blunting), and cognitive impairments. While antipsychotic medications are the primary treatment, approximately 20–30% of individuals with schizophrenia do not …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 43–48 Read article
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A Review of Telepharmacy: Advancements, Challenges, and Future Directions
Abstract: Like telemedicine, telepharmacy is a relatively new term that describes the delivery of pharmacological services. While tele comes from the Greek word “Telos,” which means from a distance, medicine comes from the Latin word “Meden,” which means to heal. The National Association of Boards of Pharmacy defines telepharmacy as the use of information and communication technology to provide patients with pharmaceutical treatment from a distance. Clinical pharmacy services are provided …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 34–42 Read article
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Review on Elaeocarpus Ganitrus (Rudraksha)
Abstract: The seed of Elaeocarpus Ganitrus, also known as Rudraksha, is renowned for its electromagnetic characteristics. Recent scientific research has demonstrated that this seed possesses natural electromagnetic properties which can effectively treat various chronic diseases. This study focuses on the phytochemical screening and thin layer chromatographic analysis of the extract obtained from Elaeocarpus Ganitrus seeds, which belong to the Elaeocarpaceae family. Bombay, and is commonly grown as an ornamental tree in …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 2, 2024 · pp. 8–15 Read article
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Pharmacological evaluation of Hepatoprotective activity of Indian medicinal plants Cordia Myxa and Canscora diffusa on wistar albino rats
Abstract: Two plants (Cordia myxa and Canscora diffusa), which were claimed to possess hepatoprotective activity, were selected. The Selected plants were authenticated by an expert botanist. In the current study, herbal extraction involving solvents of decreasing polarity (petroleum ether, ethyl acetate, and hydroalcoholic) was used to extract bioactive compounds from the plants of Cordia Myxa and Canscora diffusa in polyherbal preparations. A phytochemical evaluation was performed, including an acute toxicity study …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 31–44 Read article
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The Hidden Struggle: Premenstrual Depression its Impact on Women’s Health and Management Strategies: A Narrative Review.
Abstract: Background: Premenstrual depression, including Premenstrual Syndrome (PMS) and Premenstrual Dysphoric Disorder (PMDD), represents a significant yet underrecognized contributor to women’s mental health burden. Hormonal fluctuations during the luteal phase interact with neurotransmitter systems, particularly serotonin and GABA, leading to affective and somatic symptoms that impair daily functioning. Objective: This systematic review synthesizes evidence on the prevalence, pathophysiology, psychological impact, and management strategies of premenstrual depression among reproductive-aged women, with particular …
Published in International Journal of Nutritions · Vol. 3, Issue 1, 2026 · pp. 21–32 Read article
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Strategies in the Delivery of Nonsteroidal Antiinflammatory Drugs
Abstract: Non-steroidal anti-inflammatory drugs [NSAIDs]. are widely used for the management of pain, inflammation, and fever. However, their effectiveness is often limited by gastrointestinal side effects such as ulceration and bleeding, as well as systemic complications including renal toxicity and cardiovascular risks. To address these challenges, various strategies have been developed to improve the delivery of NSAIDs, aiming to enhance their therapeutic efficacy while minimizing adverse effects. This abstract provides an …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 44–61 Read article
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Modernizing Pharmacovigilance: Leveraging AI, Automation, and Real-World Data for Drug Safety
Abstract: Pharmacovigilance, or PV, is “the pharmacological science relating to the detection, assessment, understanding, and prevention of adverse effects, mainly long term and short-term adverse effects of medicines.” PV’s specific objectives are to increase patient care and safety when using medications and all medical and paramedical therapies; assist in evaluating the benefits, drawbacks, efficacy, and risks of medications, ensuring their safe, prudent, and more effective use; and promote clinical training, education, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 1, 2026 · pp. 12–21 Read article