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153 articles for “metabolite”
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Phytochemistry and Antimicrobial Potential of Apang (Achyranthes aspera L.): An Update Review
Abstract: Normal 0 false false false EN-US X-NONE X-NONE With the increase of synthetic antibiotic resistance and severe side effects, the pharmaceutical industry is interested in finding new drugs from natural sources with fewer or no side-effects. The present review deals with the phytochemical and antimicrobial aspects of Achyranthes aspera- a commonly used folk medicinal plant in Bangladesh and other tropical countries. Different parts of this plant (leaf, root, stem and …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 3, Issue 2, 2012 · pp. 1–8 Read article
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Evaluation of Mixed Heterotrophic Microbial Consortium Obtained from Indian Cow Dung for Biological Hydrogen Production
Abstract: The mixed heterotrophic microbial consortium isolated from Indian cow dung was investigated for the effect of pH ranging between 5.0 and 8.0 on its fermentative hydrogen-producing ability, end-metabolite and glucose-conversion efficiency. 1% w/v glucose was supplemented as carbon source. Results showed that mixed microbial consortium exhibited maximum hydrogen production and percentage glucose conversion efficiency at pH 7.5. From the investigation of total VFA content on HPLC, acetate was reported as …
Published in Journal of Alternate Energy Sources & Technologies · Vol. 4, Issue 3, 2013 · pp. 1–6 Read article
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Effect of Salt Stress on Plants: A Review
Abstract: AbstractSalinity may be a major abiotic stress, limiting growth and productivity of plants in many areas of the world. The ability of plants to tolerate salt is set by multiple biochemical pathways that facilitate retention and/or acquisition of water, defend plastid functions, and maintain ion homeostasis. The ability of plants to detoxify radicals underneath conditions of salt stress is perhaps the foremost essential demand. Several salt-tolerant species accumulate methylated metabolites …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 4, Issue 3, 2015 · pp. 35–51 Read article
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A Review on Biological Control of Plant Pathogen
Abstract: AbstractFungi of the genus Trichoderma are biocontrol agents that are successfully used as biopesticides worldwide. Several species of Trichoderma are reported to produce secondary metabolites with antibiotic activity. It is well documented that the interaction of Trichoderma strains with the plant may promote growth, improve crop yield, increase nutrient availability, and enhance disease resistance. In addition, some species of Trichoderma are able to colonize root surfaces, interact with the plant, …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 8, Issue 3, 2019 · pp. 24–27 Read article
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Antibacterial Activity of Plant Extracts and Its Phytochemical Analysis
Abstract: Emergence of multi-drug resistance in human and animal pathogenic bacteria as well as undesirable side effects of certain antibiotics has triggered immense interest in the search for antimicrobial drug of plant origin since there is no resistance developed to the drugs that are of plant origin. The antibiotic resistance was observed by testing with commonly used antibiotics against test microorganisms and then diameter of zone of inhibition was compared to …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 1, 2019 · pp. 1–11 Read article
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Wound Healing Potential of Medicinal Plants: A Review
Abstract: Wound healing is an integrated cellular and biochemical process of restoring normal structure functions of damaged tissue. Healing is a natural phenomenon by which body itself overcome the damaged to the tissue, but the rate of healing is very slow and chance of microbial infection is high. Improvement in healing process can be accomplished either by shortening the time required for healing or to minimize the undesired consequences. India has …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 4, Issue 2, 2017 · pp. 17–40 Read article
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An Introduction of Glycoside- “It’s Classification, Biogenesis, Identification, Extraction and Healthful Uses”
Abstract: A glycoside is a molecule within which a sugar is absolute to another functional group through a glycoside bond. Glycosides play various vital roles in living organisms. Several plants store chemicals within the kind of inactive glycosides. It may be activated as thanks to that sugar half broken off then its creating the chemical offered to be used. In common terms, an organic compound is any molecule within which a …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 2, Issue 3, 2015 · pp. 4–11 Read article
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Estimation of the Total Phenol Contents of the Stem of the Anogeissus pendula
Abstract: Plants are the greatest gift to human kinds; they are the sources of various kinds of metabolites of known as well as unknown composition. Secondary metabolites are the compounds which are non-nutrient and are rich sources of other activity in the plants. Plant phenolics are the compounds which have phenyl ring in them in addition to two or more hydroxyl rings; they perform variety of function in plants such as …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 5, Issue 3, 2018 · pp. 5–7 Read article
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Metabolomics: At a Glance
Abstract: Metabolomics is the branch of science which provides the comprehensive analysis of metabolites in a biological system which in turn is useful as a marker. Metabolomics analysis is useful for ascertaining human health conditions. It will provide an insight to cellular metabolism. Since the metabolome directly reflects physiological states, it can biochemically monitor disease states and assess drug actions, improving the preclinical to clinical translation and focusing on predictability, efficiency …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 4, Issue 1, 2017 · pp. 23–30 Read article
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Synthesis and Characterization of Silver Nanoparticles by using Aqueous Leaf Extract of Tecomella Undulata (SM.) seem. and their Antibacterial Properties
Abstract: Abstract The efficient protocol for bio-synthesis of silver nanoparticles (AgNPs) using Tecomella undulata leaves was developed. The present study revealed that bio-active compounds and secondary metabolites present in the aqueous extract function as stabilizing agent for AgNPs. UV-Visible spectro-analysis and FTIR confirm the presence of bioactive compounds and TEM, EDX and XRD studies confirm the crystalline nature, structure and surface morphology of silver nanoparticles produced from the plant Tecomella undulata. …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 7, Issue 2, 2020 · pp. 5–13 Read article
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Bioactive Compounds in Ethanolic Extract of Strychnos innocua Root Using Gas Chromatography and Mass Spectrometry (GC-MS)
Abstract: Medicinal plants are of great relevance with endless pharmaceutical and therapeutic properties. They are source of wide array of secondary metabolites or bioactive compounds/phytochemicals (phenols, alkaloids, flavonoids, terpenoids, tannins, steroids and saponins) which can discharge numerous biological functions (antimicrobial, antioxidant, antiviral, antifungal, anti-fibrotic, immune-modulatory, cytotoxic, antipyretic, antitumor, antihelminthic, antiprotozoal, antibacterial, and so on). The use of gas chromatography and mass spectrometry analysis in identifying the bioactive compounds in the ethanolic …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 9–14 Read article
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Exploring the properties and extraction of neem leaves
Abstract: Neem (Azadirachta indica) is a versatile medicinal plant, for its diverse therapeutic properties. This abstract provides a comprehensive overview of recent research focusing on phytochemical analysis, biochemical characterization, and antimicrobial susceptibility testing of Neem extracts. Utilizing the different from of chemical used in it, phytochemical analysis identified a plethora of secondary metabolites within Neem, including alkaloids, flavonoids, terpenoids, steroids, saponin, tannins, quinone, and phenolic compounds, indicative of its complex chemical …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 2, 2024 · pp. 32–39 Read article
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Harnessing the Medicinal Potential of SwertiaChirata: A Phytochemical Strategy for Controlling Coronavirus Symptoms Like High Fever and Anxiety
Abstract: The current investigation focuses on exploring the therapeutic capacities of SwertiaChirata, colloquially known as Chirata, in managing the symptomatic displays of coronavirus infections. Chirata, a member of the Gentianaceae family, is a distinguished herb extensively used in Ayurvedic and Unani medicinal traditions, acknowledged for its myriad of healing qualities. In addition to its regular use in combating fever and loss of appetite, its prominent antioxidant traits position it as an …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 1, Issue 2, 2023 · pp. 27–31 Read article
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Molecular Docking and Interaction of Anthocyanin Derivatives in Regulating Hippo-taz Pathway for Renal Injuries
Abstract: Introduction: The Hippo pathway plays a pivotal role in renal disease, with Yes-associated protein (YAP) exhibiting promise for combined treatments. The crucial evaluation of YAP-targeted drug safety and efficacy through preclinical studies is imperative. Additionally, α-SMA and SMAD3 emerge as potential therapeutic targets in renal fibrosis, driving ongoing research toward innovative interventions. Materials and Methods: In the systematic identification of therapeutic secondary metabolites, Anthocyanin derivatives were methodically retrieved from the …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 23–38 Read article
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Evaluation Of Anti Obesity Activity Of Citrus Sinensis & Citrus Limon By High Fat Diet Induced Model Using Danio Rerio
Abstract: Obesity, defined by the World Health Organization (WHO) as an abnormal or excessive fat accumulation that may impair health, is becoming one of the greatest challenges to global health in this millennium, with more than 300 million men and nearly 450 million women obese globally in 2018. Obesity turns into serious problem globally. Zebrafish model can be used extensively for drug screening due to its low maintenance cost, comparatively short …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 1, 2024 · pp. 24–31 Read article
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Introduction to Biological Networks and their Contributions to Systems Biology
Abstract: Biological networks provide a conceptual framework to represent and analyze the intricate interconnections among the numerous components that make up living systems. This review paper elucidates the foundational principles of networks and their diverse applications in systems biology, highlighting their crucial role in understanding the inherent complexity of biological processes. Utilizing graph theory, these networks represent entities like genes, proteins, and metabolites as nodes, with their interactions depicted as edges. …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 53–70 Read article
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Hydroponics Culture Regulated Metabolic Variations in Plants of Medicinal Value
Abstract: The current review chiefly brings to light the importance of alternative cultivation strategies for medicinal plants about the effective enhancement of the bioactive substances. The fast-paced society is favoring the need for its cost-effective cultivation and studying the effects thereafter. The mis-steps while collecting the plant from the wild lead to identification issues, genetic and phenotypic variations, variable bioactive substances/secondary metabolites, and toxic compounds. So, cultivation happening in controlled environments, …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 2, 2024 · pp. 14–20 Read article
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Assessing the Efficacy of Carica Papaya Leaf Extract in Preventing Thrombocytopenia: A Review
Abstract: A clinical condition known as thrombocytopenia is characterized by a low platelet count (less than 150 × 103/μL) in the blood, which leads to an imbalance in hemostasis and can result in multiple deadly consequences. Although the exact causes are not always known, they always lead to death by interfering with the formation of platelets and encouraging their destruction. Research demonstrates that Carica papaya leaf has special medicinal and therapeutic …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 2, 2024 · pp. 25–33 Read article
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Characterization Of Senna Occidentalis (Link.) Seed Extract
Abstract: Senna occidentalis (L.) Link commonly known as "coffee senna" or majamfari/rai dore in Hausa is a plant with a long history of traditional and medicinal uses against diseases such as inflammation, pains, and diabetes. This study presents characterization of the bioactive compounds of the seed extracts. Physicochemical analysis of seed powder was carried out following standard procedures. Qualitative phyto-chemical contents were determined for the presence and absence of major metabolites. …
Published in Research & Reviews : Journal of Botany · Vol. 13, Issue 3, 2024 · pp. 13–22 Read article
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A Review on Phytochemistry and Pharmacology of Macaranga peltata
Abstract: Macaranga peltata, categorized within the Euphorbiaceae family, represents a prevalent pioneer arboreal species across Southeast Asia, specifically in regions such as India and Sri Lanka. This review scrutinizes the phytochemical properties and pharmacological profiles of Macaranga peltata, underscoring both its historical medicinal applications and prospective therapeutic roles. The plant exhibits a rich composition of secondary metabolites, encompassing flavonoids, stilbenes, tannins, and terpenes, with the majority of these compounds being extracted …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 50–59 Read article