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231 articles for “global optimal”
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Advancing Gene Therapy: Next-Generation Viral Vector Engineering for Precision, Safety, and Scalability
Abstract: Gene therapy has emerged as a paradigm-shifting modality for the treatment of genetic disorders, malignancies, and rare diseases through the delivery of therapeutic nucleic acids aimed at correcting or modulating dysfunctional gene expression. Among the various delivery systems, viral vectors including adeno-associated viruses (AAVs), lentiviruses, adenoviruses, retroviruses, and herpes simplex viruses have proven indispensable owing to their high transduction efficiencies and adaptability. This review offers a comprehensive assessment of viral …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 37–55 Read article
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Comparative Efficacy and Safety of Safinamide and Rasagiline in the Treatment of Parkinson’s Disease: A Meta-Analysis and Systematic Review
Abstract: Background: Recent studies have suggested Rasagiline and Safinamide monotherapy as potential management options for Parkinson’s disease. Parkinson’s disease, a neurological disorder characterized by tremors and movement difficulties, necessitates treatments aimed at managing clinical symptoms. Levodopa remains the primary effective treatment for Parkinson’s disease symptoms; however, its long-term use often leads to motor complications in many patients. Additional therapeutic drugs, such as dopamine agonists and monoamine oxidase B inhibitors, including Safinamide …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 74–91 Read article
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Nanofluids: Advanced Synthesis Methods, Innovative Applications, and Future Directions
Abstract: Nanofluids, a novel mixture of nanoparticles and base fluids, is an innovative blend that has appeared as a transformative advancement in heat transfer and thermal management technologies. This study is going to discuss advanced synthesis methods, properties, and extensive applications of nanofluids in various fields, such as biomedical engineering, electronics cooling, solar energy, and machining. Optimization techniques such as nanoparticle selection, concentration control, and computational fluid dynamics modelling are also …
Published in Journal of Nuclear Engineering & Technology · Vol. 15, Issue 1, 2025 · pp. 1–11 Read article
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Pharmacovigilance And Drug-Induced Toxicities: A Clinical Perspective
Abstract: Pharmacovigilance, which aims to detect, assess, and prevent medication-induced toxicities and adverse drug reactions (ADRs), is a crucial part of healthcare. This study examines the several kinds of drug-induced toxicities, such as idiosyncratic, dose-dependent, and allergic reactions, and emphasizes the function of clinical pharmacists in the tracking and treatment of these illnesses. Pharmacovigilance systems are crucial because they can identify and handle drug-related safety issues that might not surface during …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 3, 2024 · pp. 17–30 Read article
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Saccharomyces Cerevisiae and Pichia Pastoris Optimize NH4NO3 by 50 % in Solanum Lycopersicum Preventing N2O Release.
Abstract: In agriculture, the unregulated application of NH4NO3 for healthy growth of Solanum lycopersicum is associated in the soil with the denitrification of free NO3- (nitrate), with an increase in N2O, a greenhouse gas, that contributes to global warming, loss of soil fertility. An ecological option to avoid denitrification that releases N2O as other environmental problems is to inoculate S. lycopersicum seeds with endophytic yeasts that promote plant growth, such as …
Published in International Journal of Pollution: Prevention & Control · Vol. 2, Issue 1, 2024 · pp. 7–13 Read article
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Reducing Environmental Impact through Optimized Non-Renewable Resource Management: A Systematic Review of Technological Advances
Abstract: The term "optimized use of non-renewable resources" describes the prudent management and optimization of limited natural resources that are difficult to replenish or regenerate quickly. Minerals, nuclear fuels, and fossil fuels (coal, oil, and natural gas) are examples of resources that are not renewable. The abstract idea is to minimize waste, the impact on the environment, and the pace of depletion while optimizing the utility obtained from these resources. Advanced …
Published in Journal of Nuclear Engineering & Technology · Vol. 14, Issue 3, 2024 · pp. 12–19 Read article
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Next-Generation Membrane Materials: Advances, Applications, and Challenges
Abstract: Advanced membrane materials are better than regular polymers because they are more selective, permeable, and stable. New developments in nanomaterials, composite membranes, and surface engineering are making it possible to do more with water purification, gas separation, biomedical applications, and energy systems. Membrane technologies have become important tools in many areas, including biomedicine, energy systems, gas separation, and water purification. Recent progress in material science has made it possible to …
Published in International Journal of Membranes · Vol. 2, Issue 2, 2025 · pp. 19–28 Read article
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Smart Service Solutions AI: AI-driven Multimodal Search for Home Appliance Support
Abstract: The global home appliance services market is projected to reach USD 1,203.11 billion by 2032, driven by smart household appliances. Essential services like installations, maintenance, and repairs ensure optimal performance and longevity, leading to higher customer satisfaction and loyalty. The service station partner ecosystem is crucial for ongoing support and profitability. However, challenges such as identifying the right manuals, finding relevant parts, and providing accurate instructions must be addressed to …
Published in Journal of Instrumentation Technology & Innovations · Vol. 15, Issue 3, 2025 · pp. 27–43 Read article
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Plasma Gasification for Sustainable Waste Management: Challenges and Future Prospects
Abstract: Plasma gasification technology offers a promising solution for the sustainable disposal of municipal solid waste (MSW) by converting waste into energy or valuable products, aligning with the principles of the circular economy. Despite its potential, plasma gasification faces challenges in terms of high operational costs, energy demands, and limited commercialization success. This article critically evaluates plasma gasification alongside traditional MSW processing methods, including biological, hydrothermal, and thermochemical techniques, comparing their …
Published in Journal of Materials & Metallurgical Engineering · Vol. 14, Issue 3, 2024 · pp. 01–05 Read article
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Evaluating the behavior of Concrete after addition of stone dust to steel fiber reinforced concrete
Abstract: In contemporary construction practices, the utilization of concrete has become indispensable for various civil engineering projects worldwide. Concrete, augmented with both natural and artificial fibers, plays a crucial role in bearing compressive loads and efficiently transferring structural loads to the reinforcement and foundation. The current research delves into exploring the transformative effects of different mix designs, incorporating varying percentages of steel fibers, on the behavior of concrete. The study encompasses …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 12–19 Read article
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Smart Management of EV Charging Station Using AI Chatbot & TOM API
Abstract: This paper endeavors to address the pressing challenges associated with EV charging by proposing a comprehensive smart management system for EV charging stations. The system aims to streamline the EV charging process, making it more accessible, convenient, and sustainable for users. By harnessing the power of renewable energy sources, particularly photovoltaic systems, the paper seeks to mitigate the environmental impact of EV charging while simultaneously optimizing resource utilization. Through innovative …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 14, Issue 2, 2024 · pp. 16–23 Read article
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Low-Grade Heat Recovery: Emerging Materials and Systems for Efficient Utilization
Abstract: Low-grade heat (LGH), generally characterized by temperatures below 200°C, constitutes a significant portion of wasted thermal energy in industrial, commercial, and even residential processes. Despite its vast availability, the efficient recovery and utilization of LGH remains underdeveloped due to its inherently low exergy content and the limitations of traditional heat recovery technologies. The creation of cutting-edge materials and creative system-level approaches for LGH recovery has accelerated significantly as companies continue …
Published in International Journal of Energy and Thermal Applications · Vol. 3, Issue 1, 2025 · pp. 24–29 Read article
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Algorithmic Ecology: A Framework for Achieving Carbon-Neutrality in Global Data Infrastructure
Abstract: The exponential growth of digital infrastructure has positioned data centers as critical enablers of the global digital economy, yet their environmental impact has become a paramount concern. Data centers consumed approximately 205 TWh globally in 2018, representing about 1% of global power usage with a steady 6% growth trend. This review synthesizes current literature on green algorithms and sustainable data center technologies, examining the intersection of artificial intelligence, machine learning …
Published in International Journal of Sustainability · Vol. 3, Issue 1, 2026 · pp. 33–48 Read article
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Green Technology Incubator for Sustainable Manufacturing Solutions
Abstract: The transition to a sustainable, low-carbon economy requires innovative approaches to industrial processes, particularly in the manufacturing sector, which is one of the largest contributors to global environmental degradation. This project proposes the creation of a Green Technology Incubator designed to accelerate the development of sustainable manufacturing solutions by nurturing startups and entrepreneurs focused on green technologies. The incubator's focus will be on promoting circular economy practices, energy-efficient manufacturing processes, …
Published in Journal of Nuclear Engineering & Technology · Vol. 15, Issue 1, 2025 · pp. 22–27 Read article
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Various Methods For Plastic Waste Pyrolysis To Fuels: A Review
Abstract: The world's decreasing oil reserves and increasing energy demands are pushing experts to explore alternative ways of producing premium oils that can replace fossil fuels. Waste-to-energy recovery, which involves converting waste materials into energy, shows great potential for managing waste. Waste plastics, abundant and with a high combustion heat, are attractive for energy conversion. However, the vast use of plastic products, both industrially and domestically, leads to a surge in …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 79–93 Read article
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Advancements in Antiviral Therapeutics: Strategies and Challenges in the Development of Drugs and Vaccines for Viral Diseases
Abstract: Viral infections continue to pose a significant threat to global health, leading to high rates of illness, death, and economic burden. The constantly evolving nature of viruses, along with the rise of drug-resistant strains, underscores the need for continuous advancements in antiviral treatments. This review highlights the pivotal role of antiviral drugs and vaccines in mitigating the impact of viral infections, showcasing recent breakthroughs and exploring emerging technologies. Key advancements …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 32–36 Read article
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Harnessing Deep Learning to Explore Microbial Community Structure and Carbon Storage Capacity in Mangrove Ecosystems: A Framework for Computationally
Abstract: Mangrove ecosystems represent one of the most efficient natural carbon sinks on Earth, functioning as critical blue carbon habitats that sustain diverse microbial communities responsible for biogeochemical cycling and long-term carbon storage. Despite their global ecological significance, accurately quantifying and predicting carbon sequestration in mangrove systems remains challenging due to the complex interactions between microbial diversity, sediment chemistry, and environmental drivers. This study presents a comprehensive and sustainable artificial intelligence …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 1, 2026 Read article
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The Future of Camelids in South America: Recent Developments and Prospects
Abstract: Camelids, including llamas, alpacas, vicuñas, and guanacos, have been central to South American culture, economy, and ecosystems for centuries. Known for their adaptability to harsh Andean climates, these species provide valuable resources, such as luxurious fiber, nutritious meat, and durable leather. In modern times, their importance has grown due to increasing demand for sustainable and ethically sourced products, coupled with their minimal environmental impact and significant contributions to rural livelihoods. …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 14, Issue 2, 2025 · pp. 35–38 Read article
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Enhancing Abiotic Stress Tolerance in Banana (Musa spp.) Using In Vitro Methods and Conserving Germplasm
Abstract: Both biotic and abiotic stressors are the main factors limiting banana output. Research on biotic stressors in bananas has received enough attention globally, whereas abiotic stressors receive less attention. Water availability, salinity, and a wide variety of temperatures are the main problems that must be resolved to maintain banana farming in the twenty-first century. Samples were introduced with water, salt and heat stresses in invitro condition. Under different stress and …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 14, Issue 1, 2025 · pp. 9–15 Read article
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Innovative Approaches in Bioinspired and Biomimetic Membrane Technologies: Bridging Nature and Engineering
Abstract: Bioinspired and biomimetic membranes represent a ground breaking advancement in membrane technology, offering innovative solutions to critical global challenges in water purification, chemical separation, and energy conversion. These membranes leverage the exceptional transport properties of biological systems, particularly through the incorporation of aquaporin proteins, which facilitate rapid and selective water transport. This review synthesises recent developments in aquaporin-based membranes, highlighting their remarkable efficiency in desalination processes, where they serve as …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 53–60 Read article