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188 articles for “bio-active compounds”
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Randomized Clinical Study on Dissolution of Urinary Catheters and Stents Encrustation by an Ayurvedic Compound
Abstract: Encrustation, a crust or hard coating on the surface of urinary catheter and stents, is developed due to the formation of biofilm. Encrustation causes blockage of urinary catheter and leads to reflux of urine, increases renal pressure and ultimately damages renal parenchyma tissues. Present clinical study was designed to evaluate the dissolution activity of an Ayurvedic compound on catheter and stent encrustation and to study the changes seen in serum …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 2, Issue 3, 2013 · pp. 12–24 Read article
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Synthesis, Characterization of New Imidazolidin-4-One Containing Azo Compound Derived from Acetylacetone as Antibacterial and Antioxidant Agents
Abstract: In the present study, new derivatives of imidazolidine-4-one was prepared. Which involved reactions to diazonium salt of o-methoxy aniline with acetylacetone in the presence of sodium hydroxide, and isolating the azo compound as a brown precipitate. The azo diketone reacts efficiently with aromatic amine derivatives to produce Schiff bases as a light yellow and dark brown precipitates, and from this Schiff bases three derivatives of imidazolidine-4-one was prepared by reacting …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 17, Issue 1, 2026 · pp. 94–114 Read article
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Restoration of Degraded Agricultural Soils Through Organic Amendments and Sustainable Farming Practices
Abstract: This study investigates the efficacy of organic amendments and sustainable farming practices in restoring degraded agricultural soils, addressing a critical global challenge affecting food security and environmental sustainability. The research was conducted over three growing seasons on degraded semi-arid agricultural land, utilizing a randomized complete block design with five treatments: The following farming practices: pure control, organic amendments but market conventional farming practices, sustainable farming practices but market standard conventional, …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 13, Issue 3, 2024 · pp. 19–27 Read article
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Molecular Docking Study: Targeting mycobacterium leprae ML2640 Protein Using Active Compounds from Coscinium fenestratum
Abstract: Objectives: Leprosy is an infectious disease in skin, peripheral nerve and mucosa of upper airway. Around 70% of this infection is caused by Mycobacterium leprae, which was discovered during1873. Multi drug therapy is used for the treatment, still multiple drug resistance and reactions has been reported among patients. Hence, this work focused on identifying bioactive compounds from Coscinium fenestratum that can target mycobacterium leprae ML2640 protein by in-silico approach. Method: …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 21–33 Read article
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Fungal-derived Nutraceuticals & Bioactive Compounds with Physiotherapeutic and Health- promoting Properties: A Comprehensive Review
Abstract: Fungal-derived nutraceuticals represent a rapidly expanding field in biomedical research, offering a rich source of bioactive compounds with diverse therapeutic applications. This comprehensive review examines the physiotherapeutic and health-promoting properties of fungal metabolites, including polysaccharides, terpenes, proteins, peptides, alkaloids, fatty acids, vitamins, and minerals. Fungi produce over 9,000 bioactive compounds from approximately 22,500 microbial metabolites, with less than 5% of the fungal kingdom explored [1] . The major bioactive constituents …
Published in International Journal of Fungi · Vol. 2, Issue 2, 2025 Read article
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Natural and synthetic pesticide and their effect on life
Abstract: Natural and synthetic pesticides both play roles in pest control but differ significantly in their impact on life and the environment. Natural pesticides, often derived from plants and microorganisms, are biodegradable, eco-friendly, and generally exhibit lower toxicity to non-target organisms and humans. Synthetic pesticides, while highly effective in pest control and used extensively in conventional agriculture, tend to have greater toxicity, persist longer in the environment, and pose more significant …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 3, 2025 · pp. 8–13 Read article
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Chalcones: Beyond Bioactive Properties - Exploring Their Potential as Polymeric Materials
Abstract: Chalcones, a class of natural compounds characterized by their unique chemical structure, have garnered significant attention in recent years for their diverse pharmacological and biological activities. This review aims to comprehensively assess and summarize the latest research spanning the last five years. By synthesizing findings from a plethora of studies, this retrospective analysis elucidates the evolving landscape of chalcone research, shedding light on their therapeutic potential and biological effects. The …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 997–1003 Read article
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Enhancing the Bioavailability of Polyphenols: A Comprehensive Review
Abstract: The polyphenolic compounds are abundantly found in different plant parts including fruits, leaves, stem and seeds, and are known for possessing a wide range of biological activities. These include antioxidant, antimicrobial, anti-inflammatory, anticancer, antidiabetic, cardioprotective, and neuroprotective effects. Their functional relation with their structure highlights the significant therapeutic potential. As a result, the polyphenols are being further being exploited for applications in functional foods, pharmaceuticals, and targeted drug delivery. Despite …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 15, Issue 2, 2026 · pp. 37–51 Read article
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Therapeutic Potential of Terminalia arjuna Bark in the Management of Hemorrhoids: A Comprehensive Review
Abstract: Background: Hemorrhoids appear frequently among anorectal disorders since they create vascular swelling together with pain symptoms, while leading to bleeding and mucosal tissue tending to slide out. Though effective therapy exists, traditional treatments produce various adverse effects and lead to recurrence and inconsistent patient following of medical recommendations over the long term. Plantbased therapeutic medicines have gained rising demand, which leads experts to investigate medicinal plants with established pharmacological effects. …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 2, 2025 · pp. 22–32 Read article
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Harnessing the Bioactive Potential of Calotropis gigantea and Calotropis procera
Abstract: The medicinal plants of the Apocynaceae family Calotropis gigantea and Calotropis procera have gained more and more interest as source of bioactive molecules for biomedical applications like cancer therapy. They have various pharmacological activities, which are believed to be linked to various phytochemical constituents such as cardenolides, cardiac glycosides, flavonoids, triterpenoids, steroids, phenolic compounds, alkaloids, and proteins in their latex. The recent molecular and cellular studies show that extracts and …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 2, 2026 Read article
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Extraction and Compound Analysis of Bauhinia acuminata: Soxhlet Method and Identification
Abstract: In the present study, the extraction and compound analysis of Bauhinia acuminata using the Soxhlet method, coupled with identification techniques, were conducted. Bauhinia acuminata L., a member of the Leguminosae (Fabaceae) family in the Caesalpinioideae subfamily, is a shrub usually reaching a height of around 3 m. It is native to tropical Southeast Asia and commonly found in the tropical regions of India and China. Primarily grown for ornamental purposes, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 2, 2024 · pp. 18–23 Read article
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Exploring Abies grandis phytocompounds potential by in silico analysis targeting on the 5P9J Protein
Abstract: Blood Cancer, also popular with name ‘Hematologic cancer’ have variety of types: Leukaemia, Lymphoma, Myeloma, uncontrolled multiplication of blood cells mainly affecting to bone marrow and blood cells (White Blood Cells). Lymphoma, originating from lymphatic system resulted in uncontrolled growth and instead of normal apoptosis development of tumor. Myeloma, uncontrolled formation of malignant plasma cells leads disrupting production of healthy blood cells. This situation creates variety of diseases like anaemia, …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
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Chemical Composition and Antimicrobial Efficacy of Ferula persica Extracts: A Phytochemical and Bioactivity Assessment in Iraq
Abstract: The research presented in the tables focuses on analyzing the chemical content of extracts from the Ferula persica plant, a wild species in Iraq with significant medical and therapeutic importance dating back to ancient times. This study involved testing some chemical and physical properties of the alcoholic extract of the plant's aerial parts and evaluating its antimicrobial activity, specifically against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli). The …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 10–22 Read article
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Psychoactive and Physiological Homogeneity of Cannabis: A Literature Review: Actions of the Medical Plant that Takes Care of Itself
Abstract: Naturally occurring plants like Cannabis and the biologically ubiquitous alkaloids (e.g., morphine, quinine, and atropine) are composed of mostly physiological and psychoactive compounds. Extracts of the Cannabis plant are not alkaloid substances nor are they not related chemically to alkaloids, having no component nitrogen in their structures. Three species of Cannabis (marijuana) are recognized in scientific classifications: Cannabis sativa, Cannabis indicus and Cannabis ruderalis. Cannabis sativa is the species that …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 2, 2017 · pp. 1–4 Read article
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Metal Complexes of Cephalexin and Their Biological Activities: A Review
Abstract: Cephalexin and its derivatives are commonly utilized in the pharmaceutical and medicinal industry due to their biological and pharmaceutical activities, including anti-microbial, anti-cancer, anti-bacterial, and herbicidal activities as well as possessing high palatability and being useful for skin and joint infections. Interestingly, some organic drugs, including cephalexin, which exhibit toxicological and pharmacological properties, can be administered in forms of metal complexes. Many researchers have synthesized organic ligands derived from cephalexin …
Published in Journal of Polymer & Composites · Vol. 11, Issue 2, 2023 · pp. 52–61 Read article
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The Effect of Prepared Biochemical Compounds on Cancer Cells
Abstract: The effect of prepared biochemical compounds affecting cancer cells, where the chemical compounds are divided into two parts, some of which are treatment for cancerous tumors, and others activate cancer cells such as glucose and sugars, which increase the size of the cancerous tumor and its spread in the body. While chemotherapy usually refers to the use of antitumor drugs to treat cancer through a cytotoxic treatment method. It also …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 11, Issue 1, 2022 · pp. 14–20 Read article
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Functional Biomolecules in Animal Nutrition: Biochemical Mechanisms and Their Impacts on Growth Performance and Health Outcomes
Abstract: Functional biomolecules have emerged as critical modulators of animal nutrition, extending beyond conventional nutrient supply to regulate biochemical and physiological processes that determine growth performance and health outcomes. This review synthesizes current knowledge on diverse classes of bioactive compounds, including amino acids, peptides, fatty acids, vitamins, minerals, phytochemicals, and microbial-derived metabolites, and their roles in livestock systems. Emphasis is placed on underlying biochemical mechanisms such as enzyme activation, nutrient signaling …
Published in International Journal of Nutritions · Vol. 3, Issue 2, 2026 · pp. 26–36 Read article
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Review on Effect of the Chemical Composition of some Pharmaceutical Vaccines and their Biochemical Efficacy with Chemical Techniques
Abstract: Chemical compounds are fundamental components in the formulation of medicines and vaccines, playing a critical role in ensuring their safety, stability, and effectiveness. Vaccines contain a combination of active and inactive ingredients, including weakened or inactivated viruses or bacteria, toxins, preservatives, stabilizers, adjuvants, antibiotics, and minerals. The active ingredient is an antigen, which stimulates the body's immune system to recognize and defend against specific infectious diseases. Adjuvants, such as aluminum …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 2, 2026 · pp. 01–09 Read article
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A Molecular Docking Study: Targetting HIV-1 Integrase Protein Against Selected Phytocompounds from Calophyllum Lanigerum
Abstract: Objectives: The most common form of HIV that causes AIDS is HIV-1. The World Health Organization has estimated roughly 75 million plus HIV-1 infections till date and roughly 40 million deaths (as of 2021). Thus, this study was done to identify natural compounds from Calophyllum lanigerum, a medicinal plant largely endemic to South-East Asia, to inhibit the spread of this disease. It did so by using molecular docking methods, Lipinski …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 2, 2023 · pp. 43–55 Read article
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Unveiling the Role of Lead Molecules in CADD: A Systematic Review
Abstract: The word "medicate plan" alludes to the objective creation of modern drugs. Arbitrary screening of engineered compounds, engineered of organically dynamic compounds based on actually happening drugs, amalgamation of basic analogs of actually happening lead particles, and usage of the bioisosteric hypothesis are a few of the strategies that have been utilized. As a result, the most recent drift in medicate plan is to either completely enhance a lead or …
Published in International Journal of Membranes · Vol. 1, Issue 1, 2024 · pp. 37–43 Read article