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82 articles for “and renal disease”
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Integration of Biomarkers in III and IV CKD Patients for Evaluation of Their Predictive Value for CVD in CKD Patients
Abstract: Background: Chronic kidney disease (CKD) is presently characterized by the presence of proteinuria and/or a diagnosis of renal impairment. The worldwide significance of CKD is underscored by the fact that its prevalence and incidence have doubled over the past three decades. This paper provides an overview of the existing evidence regarding biomarkers in individuals with CVD or CKD, with a particular focus on the emerging biomarkers (i.e., eGFR, sALB, UACR, …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 3, 2025 · pp. 1–12 Read article
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Computational Identification of Antigenic Proteins and Epitopes in Hantavirus sp. for Drug Repurposing
Abstract: Hantavirus is an emerging virus that spreads from animals to humans and can cause serious illnesses like hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal syndrome (HFRS). there are no FDA-approved treatments available for these diseases. This study explores in-silico drug repurposing as a strategy to identify potential therapeutic candidates. The physicochemical, secondary structure, antigenicity, and post-translational modification analysis of hantavirus proteins – specifically the glycoprotein precursor, N protein, …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 20–26 Read article
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Clinical and Etiological Profile of Heart Failure Patients
Abstract: This study was undertaken to study the clinical and etiological profile of patients with heart failure at Mamata General Hospital, Khammam. This is a study of clinical and etiological profile of heart failure in patients of above 15 years of age, who were admitted in Mamata Medical College during the period December 2012 to November 2013. The incidence of heart failure (HF) in Mamata General Hospital is less compared to …
Published in Research and Reviews: A Journal of Medicine · Vol. 4, Issue 1, 2014 · pp. 6–11 Read article
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Protective Role of Sulforaphane against Multiorgan Toxicity in Rats: An In-vivo and In-vitro Review Study
Abstract: Sulforaphane [1-isothiocyanate-(4R) -(methylsulfinyl) butane] is a natural dietary isothiocyanate produced by the enzymatic accomplishment of the myrosinase on glucopharanin, a 4-methylsulfinylbutyl glucosinolate contained in cruciferous vegetables such as broccoli, brussel sprouts, and cabbage. Exploring of this compound against various oxidative degenerative diseases such as hepatic, nephro and cardiac diseases is growing because of its anticarcinogenic and cytoprotective properties. In several invivo and invitro experimental paradigms proved SFN and its compounds …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 1, 2018 · pp. 1–8 Read article
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An Insight to Hyponatremia in Cirrhosis: Pathophysiology and Management Approaches
Abstract: Cirrhosis is considered by systemic and splanchnic vasodilation that principals to extreme nonosmotic excretion of vasopressin. Hyponatremia is a mutual electrolyte irregularity in progressive liver disease that outcomes from the diminished capability of the kidney to excrete solute-free water that principals to “dilutional” hyponatremia water retention uneven to the retaining of sodium. Hyponatremia is mutual in cirrhosis. It frequently happens in a progressive phase of the disease and is related …
Published in Research and Reviews : A Journal of Immunology · Vol. 10, Issue 3, 2020 · pp. 30–46 Read article
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Infection and Viral Pathogenesis of SARS-CoV-2: A Review
Abstract: COVID-19 is a highly infectious disease, posing a massive challenge to global health, with non-specific symptoms, the disease presentation can range from no symptoms (asymptomatic) to severe pneumonia and acute respiratory distress syndrome (ARDS). This review summarizes the current evidence on the major adverse pathological outcomes of COVID-19, which were found to affect different body systems like the respiratory system, cardiovascularsystem, and neurologicalsystem, as well asimpaired hepatic and renal function. …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 12, Issue 2, 2022 · pp. 17–23 Read article
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Chronic Kidney Disease: An Overview
Abstract: The key purpose of this review article is to throw light on chronic kidney disease (CKD). Each day people are diagonised with CKD making the need of proper awareness regarding CKD, one of the top public health priorities. Taking this into consideration, the review article outlines some new insight on identification of CKD, classifying it into several stages based on glomerular filtration rate (GFR)/chronic renal failure (CRF) value to be …
Published in Research and Reviews: A Journal of Medicine · Vol. 8, Issue 1, 2018 · pp. 6–9 Read article
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DRUG INDUCED IMMUNE MEDIATED NEPHRITIS: MOLECULAR MECHANISM , PATHWAYS AND CLINICAL IMPLICATIONS
Abstract: Drug-induced immune-mediated nephritis (DI-IMN) has become a more widely known cause of acute kidney injury (AKI), with the potential for development to chronic kidney disease if not detected and treated promptly. T-cell hypersensitivity to pharmaceuticals, such as antibiotics, proton pump inhibitors, nonsteroidal anti-inflammatory drugs, and immunological drugs, are the major causes for it. Beyond clinical burden, DI-IMN reflectsintricate molecular interactions that sustain interstitial inflammation and tubular injury. These interactions include …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 13–29 Read article
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The Function of Diuretics in Current Medical Practice and Prospective Advancements
Abstract: Diuretics have a rich history that spans several centuries, and this review aims to highlight their progression and clinical uses. We start by exploring kidney physiology, followed by a description of how diuretics function through symporters in the renal tubules. Different categories of diuretics are outlined, along with details of their specific actions. Next, we investigate the clinical use of diuretics in conditions, such as congestive heart failure and hypertension, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 70–75 Read article
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A Study and Report on Impact of Clinical Pharmacy Services Over Indian Health Care System in the Management of Chronic Disorders/Diseases in Hospital
Abstract: The study aims to ensure safe, effective, economic, and patient friendly with the knowledge inputs of each professional practice. With the primary and secondary objectives being: to study the role of the clinical pharmacist/doctor of pharmacy professional in the management of chronic diseases/illness, minimise medication/prescription errors, minimise/prevent adverse drug reactions, all types of drug interactions, and unnecessary healthcare costs, reducing drug-related problems and to monitor drug therapy efficiently, attain desired …
Published in Research and Reviews: A Journal of Health Professions · Vol. 11, Issue 2, 2021 · pp. 46–82 Read article
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Review on the Efficacy of Ayurvedic Formulations in Diabetes Management
Abstract: Diabetes mellitus is one of the most prevalent metabolic disorders globally, characterized by persistent hyperglycemia resulting from defects in insulin secretion, insulin action, or both. It leads to serious complications affecting the cardiovascular, renal, and nervous systems, imposing a significant health and economic burden. In Ayurveda, diabetes is described as Madhumeha, a subtype of Prameha, primarily caused by the vitiation of Kapha dosha, Meda dhatu (fat metabolism), and Agnimandya (impaired …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 1, 2026 · pp. 16–22 Read article
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Herbal Drug Used in the Treatment of Diabetes: A Review
Abstract: Background: Diabetes mellitus is a chronic disease that occurs at the point when the pancreas is not able to produce insulin, or when the body cannot utilize the insulin it produces. Diabetes mellitus is a complex metabolic disorder that affects various systems of body such as visual, circulatory, renal and nervous system. Human beings depend upon plants for their various needs such as food, fodder, fuel, timber, fibres, dyes, gums, …
Published in Research & Reviews : Journal of Herbal Science · Vol. 9, Issue 4, 2020 · pp. 27–34 Read article
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Urinary Tract Infection (Tadiya-e-Majra-e-Baul) in Unani System of Medicine
Abstract: In classical Unani system of medicine Tadiya-E-Majra-e-Baul. (Urinary Tract Infection) comes under the heading of Hirqatul-baul (burning micturition) which is caused by obstruction in Urinary Tract due to stone, Jisme Gharib (foreign body) Ghaliz Ghost (Badgosh), Hamal (Pregnancy), and Characterized by frequency of micturition, urgency of micturition, burning micturition and anuria . It is an Unani Medicine of Shora Qalmi, Rewand Chini and Kababchini. Having safe and good result in …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 7, Issue 2, 2020 · pp. 34–39 Read article
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Phytoconstituents And Pharmacological Activities Of Indian Medicinal Plant – Semal (Bombax Ceiba)
Abstract: Bombax ceiba is a member of the bombacaceae family which is sometimes referred to as red silk cotton tree and Semal. The plant is found in India, Sri Lanka, Bangladesh, Myanmar, Northern Australia,Pakistan, Java, Malaysia and Sumatra.The plant is known by various names in different languages, such as Red cotton tree and Indian kapok tree in English, Shalmali in Sanskrit, Semal in Hindi, Shimul in Bengali, M Mullilavu in Malayalam, …
Published in Research & Reviews : Journal of Botany · Vol. 12, Issue 3, 2023 · pp. 17–26 Read article
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A Study to Assess the Risk Factors Associated with Sudden Death in Population on Hemodialysis
Abstract: Background: Patients with chronic kidney disease (CKD) receiving maintenance hemodialysis (HD) experience disproportionately high mortality, with sudden death remaining a leading cause. Multiple clinical, biochemical, and care-related factors influence outcomes, yet comprehensive risk stratification models and the role of dialysis timing and early nephrology care remain inadequately explored in resource-limited settings. Objectives: This study aimed to (i) identify clinical and biochemical risk factors associated with mortality in HD patients, (ii) …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 1, 2026 · pp. 14–19 Read article
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Gene Annotation of Cancer Vaccine for Homo sapiens
Abstract: Objectives: Gene annotation helps us to deduce the structural and functional aspects of a gene that encodes for a functional protein in our body. Thus, by determining the coding sequence and gene location we can derive meaningful insights as to what these genes do in our body. In this study, an unknown gene, cancer vaccine for Homo sapiens has been studied and annotated. Methods: This study was based on a …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 1–14 Read article
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Evaluation of the efficacy and safety of Unani Medicine Tukhm-e-Karafs (Apium graveolans Linn) and Tukhm-e- Duqu (Peucedanum grande) in patients with urolithiasis by assessing the symptomatic relief, reduction/expulsion of urinary stones and urinary biochemical parameters.
Abstract: Background: - Karafs(Apium graveolans Linn) and Duqu (Peucedanum grande) are some of the main plants whose seeds are used in Unani System of Medicine from ancient times for a number of problems of urinary system like urinary retention, kidney and bladder stones , and other kidney diseases like nephrits, etc.Aim of the study: - To evaluate the efficacy and safety of Unani Medicine Tukhm-e-Karafs (Apium graveolans Linn) and Tukhm-e- Duqu …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 9, Issue 3, 2022 · pp. 22–27 Read article
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Cadmium and Apoptosis: A Molecular Approach
Abstract: Apoptosis, also known as programmed cell death is a highly regulated and fundamental process found in all multicellular organisms. It is not only implicated in regulatory mechanisms of cells, but has been attributed to a number of diseases, like inflammation, malignancy, autoimmunity and neuro-degeneration. A variability of pollutants can persuade apoptosis. Oncogenic transition metals like cadmium, promote apoptosis alongside DNA base modifications, strand breaks and rearrangements. Generation of reactive oxygen …
Published in Research and Reviews: A Journal of Toxicology · Vol. 6, Issue 1, 2016 · pp. 8–17 Read article
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Unani Opinion on Nephrolithiasis (Hisat-e- kulyah) and its Management
Abstract: Nephrolithiasis is called Hisat-e-Kulyah in Unani system of medicine. Nephrolithiasis is a disease in which crystal aggregates are generally formed in the kidneys. It is one of the most common urinary tract abnormalities affecting approximately 15% of the population worldwide and approximately 2.3% of the population in India. Since historical times, Urolithiasis (Hisat-e-Bauliyah) or Hisat-e-Kulyah (Nephrolithiasis) has been treated by Unani doctors such as Hippocrates, Galen, Avicenna, Razi, Ibn- e-Zohr …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 9, Issue 3, 2022 · pp. 17–21 Read article
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A Rare Cause of Parkinsonism—Manganese Toxicity
Abstract: A 43-year-old male presented with six months history of gradual onset and progressive bradykinesia, tremors of upper limbs and walking difficulty in the form of imbalance and short shuffling gait. He also had slurring of speech with hypophonia. Neurological examination revealed slow broken saccades, rigidity with cogwheeling, bradykinesia and short shuffling, festinant gait. He had action and postural tremors of upper limbs. Pull test was positive. Thus, a diagnosis of …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 9, Issue 1, 2019 · pp. 29–32 Read article