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161 articles for “Sustain Release”
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Maximizing In Situ Formulation Adhesion Potential By Testing Different Polymer
Abstract: This study explores the use of a in-situ ocular gel delivery system for gentamicin sulphate. The anatomy of human eye consists of the cornea, lens, aqueous humor, vitreous humor, and retina. The physiology of the human eye involves the production of tears and the process of accommodation. Eye infections are caused by viruses, fungi, bacteria, or parasites. The symptoms of eye infection can include redness, itching, burning, watering, discharge, and …
Published in Trends in Drug Delivery · Vol. 10, Issue 1, 2023 · pp. 1–10 Read article
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Formulation and development of Lamivudine Nanoemulsion by using Emulsifying Polymers and It’s Evaluation
Abstract: Nanoemulsion is a novel approach to medicine delivery that helps to increase the bioavailability of drugs that aren’t particularly soluble in water. In this research work, nanoemulsion of Lamivudine was formulated by using polymers such as SPAN 80, TWEEN 80 and Whey protein concentrate with the help of Ultrasonication technology. The formulation was optimized. It was evaluated by assessing pH, viscosity, turbidity, in vitro franz diffusion study, particle size distribution, …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 22–35 Read article
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Key of Certification to Scheme Nano Fertilizer
Abstract: compared with traditional fertilizers. Classes of nanofertilizers have suggested as nanoscale fertilizer i.e. nanoparticles which contain nutrients; nanoscale additives i.e. traditional fertilizers with nanoscale additives; and nanoscale coating i.e. traditional fertilizers coated or loaded with nanoparticles. Low nutrient use efficiency (NUE) values and increased environmental risks have subjected long-term limitation due to use of more synthetic fertilizers to prohibit defining achievements of sustainable agriculture. High release levels of synthetic fertilizers …
Published in Research & Reviews : Journal of Botany · Vol. 10, Issue 3, 2021 · pp. 1–8 Read article
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Formulation Development and Evaluation Technique for Immediate and Modified Release Capsule
Abstract: The development and evaluation of formulations for immediate-release (IR) and modified-release (MR) capsules represent a critical aspect of pharmaceutical dosage form design, offering distinct advantages in terms of drug release profiles and therapeutic outcomes. This study focuses on the formulation strategies, techniques, and evaluation methods used to develop both IR and MR capsules. Immediate-release capsules are designed to disintegrate quickly in the gastrointestinal tract, ensuring rapid drug absorption, while modified-release …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 1–9 Read article
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Pharmaceutical Bead Formulations: A Comprehensive Overview into Advanced Drug Delivery
Abstract: Pharmaceutical beads are a unique and flexible drug delivery vehicle that provides numerous possibilities to control the release of drugs, protect them, and increase their therapeutic performance. These beads make it possible to design several types of therapeutic regimens by incorporating active pharmaceutical ingredients in a polymeric or lipid matrix. This review discusses the bead technology in drug delivery from its inception to its present application, focusing on the most …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 78–100 Read article
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Evaluation of Mucoadhesive Polymers for Nasal Delivery of Herbal Bioactives
Abstract: A study assessed mucoadhesive polymers for intranasal herbal bioactive administration with higher residence time and mucosal permeability. Chitosan, Carbopol® 934P, and HPMC K15M were utilized to manufacture mucoadhesive nasal gels with standardized herbal bioactive fractions. Formulations were examined for pH, viscosity, spreadability, drug content, mucoadhesive strength, in-vitro release, ex-vivo penetration, and short-term stability. All formulations demonstrated a suitable pH for nasal usage and uniform drug content (97.48 ± 1.12% to …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1680–1689 Read article
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Biopolymer-Based 3D Composite Scaffolds for Bone Tissue Engineering: Photothermal-Responsive Systems with Controlled Pt (IV) Prodrug Release
Abstract: Biopolymer-based composite scaffolds have attracted significant attention as multifunctional platforms at the intersection of polymer science, regenerative medicine, and cancer nanotherapy. In this study, a dual-functional scaffold was developed for simultaneous osteosarcoma treatment and bone regeneration using poly (L-lactic acid) (PLLA) reinforced with bioactive glass (BG) and integrated with a glutathione-responsive platinum (IV) prodrug system (PDA@Pt). To improve interfacial adhesion, photothermal conversion efficiency, and tumor-specific activation, the Pt (IV) prodrug …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 351–361 Read article
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Development and Assessment of Levetiracetam Microspheres Utilizing Synthetic and Natural Polymers: A Biomedical Engineering Perspective
Abstract: In the present study, comparative study of Levetiracetam loaded microspheres using Ethyl cellulose as synthetic and Sodium alginate as natural polymers was done. Solvent evaporation and ionic gelation technique has been successfully employed to produce Levetiracetam loaded ethyl cellulose and sodium alginate microspheres with optimal drug encapsulation that sustained the drug release over a period of time. Based on the pre-formulation studies E1 to E4 and S1 to S4 batches …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 1, 2024 · pp. 1–18 Read article
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Review On: Liquid Crystal Cream for Topical Drug Delivery
Abstract: A Liquid crystal creams represent a novel approach in skincare formulations, leveraging the unique properties of liquid crystal technology to improve skin hydration and barrier function. An overview of current developments in liquid crystal cream formulations is given in this article, with an emphasis on the benefits they offer for skincare and their composition and structure. Liquid crystal creams mimic the lipid bilayers of the skin, offering enhanced compatibility and …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 1–8 Read article
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Advancing Capsule Technology: A Comprehensive Review of Formulation Strategies
Abstract: Capsules are a popular and versatile oral dosage form used in drug delivery, offering benefits such as ease of swallowing, taste masking, and improved stability of active pharmaceutical ingredients (APIs). They can be made from gelatin or non-gelatin materials like Hydroxypropyl Methylcellulose (HPMC), Polyvinyl Alcohol (PVA), and starch, catering to dietary, cultural, and sustainability needs. Capsules can be engineered for controlled, sustained, or targeted release, enhancing bioavailability, particularly for poorly …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 44–56 Read article
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A Review on Drug Delivery Systems Using Microfluidics
Abstract: AbstractMicrofluidics is undoubtedly an influential technology that is currently revolutionizing the chemical and biological studies by replicating laboratory benchtop technology on a miniature chip-scale device. In the area of drug delivery science, microfluidics offers advantages, such as accurate dosage, ideal delivery, target-precise delivery, sustainable and controlled release, several dosing, and slight side effects. These helps bring significant assets to the drug delivery systems. Microfluidic technology has been increasingly used for …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 10, Issue 1, 2020 · pp. 1–10 Read article
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Formulation and Evaluation of Gastro retentive Effervescent Floating Tablets of Famotidine: Effect of Formulation Variables and In Vitro In Vivo Evaluation
Abstract: Gastro retentive effervescent floating tablets of famotidine were developed in an attempt to sustain the drug release as well as to prolong the presence of dosage form in the stomach or upper small intestine until drug is completely released in desired period of time from the formulation with special emphasis to the effect and concentration of different polymers on drug release and floatation. Tablets were prepared by direct compression method …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 2, Issue 3, 2015 · pp. 13–29 Read article
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Carbon based Supercapacitor for Electric Vehicles
Abstract: Carbon materials, like activated carbon, and graphene, are abundant and can be produced sustainably. This eco-friendliness aligns well with the overarching goals of electric vehicle manufacturers who are keen to diminish their carbon footprint. Their compatibility with renewable energy systems also opens avenues for integrated energy solutions, enhancing overall system efficiency. Carbon-based supercapacitors hold significant promises as complementary energy storage devices in the electric vehicle landscape. While challenges related to …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 14, Issue 3, 2024 · pp. 01–11 Read article
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Influence of Polymeric Carriers on the pH-Modifying Properties of Intracanal Medicaments in Root Canal Treatment
Abstract: Calcium hydroxide (CH) preparations and medicated gutta-percha are widely used intracanal medicaments in root canal treatment. These materials often incorporate polymeric carriers to deliver the CH payload and influence its therapeutic effect. This in-vitro study investigates the impact of different polymeric carriers on the pH-modifying properties of intracanal medicaments within the root canal system. The research focuses on two key aspects: (1) the ability of the polymers to control the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 967–974 Read article
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Liposomes as Therapeutic Vehicles: Advancing Targeted Drug Delivery in Healthcare
Abstract: Liposomes represent an innovative approach to targeted drug delivery. These tiny, lipid-based vesicles can encapsulate medications, allowing them to travel directly to diseased cells while minimizing impact on healthy tissues. By using liposomes, medications can improve their effectiveness while reducing side effects, leading to better overall treatment results.. Their structure enables a controlled release of the drug, which can be particularly beneficial for therapies requiring sustained action. This technology holds …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 39–46 Read article
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Bio-Inspired Membranes in Oral Drug Delivery: A Pathway to Enhanced Permeability and Targeted Therapy
Abstract: Bio-inspired membranes in oral drug delivery represent a significant advancement in pharmaceutical technology, harnessing principles of natural biological systems to improve drug permeability, bioavailability, and targeted release. This review discusses the design, materials, and fabrication techniques used in bio-inspired membranes, with a focus on materials like chitosan, silk fibroin, and synthetic polymers that mimic biological structures. By exploring the mechanisms of drug permeation, such as mucoadhesion and selective permeability, bio-inspired …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 39–52 Read article
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Chitosan-Glycine Cross-Linked Microspheres for Controlled Release of Isoniazid
Abstract: Semi-interpenetrating polymer network microspheres of chitosan with glycine have been prepared for encapsulation and controlled release of isoniazid (INH) as a model drug. The method involved the exposure of microspheres to the vapor of cross-linking agent to effect the cross-linking under mild conditions. The swelling behavior, hydrolytic degradation and loading capacity of microspheres for INH have been investigated. The prepared microspheres have shown 96% drug loading capacity, which suggested that …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 6, Issue 3, 2015 · pp. 7–12 Read article
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Microsphere-Based Drug Delivery: A Critical Review of Innovations and Applications
Abstract: Microspheres have emerged as a revolutionary approach in pharmaceutical sciences, offering controlled and targeted drug delivery with improved bioavailability, stability, and patient compliance. These spherical carriers, ranging from nanometers to micrometers in size, can encapsulate both hydrophilic and hydrophobic drugs, enabling sustained and site-specific release. The development of microspheres has been significantly driven by the need to enhance drug efficacy while minimizing systemic side effects. This review provides a comprehensive …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
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Enhancement of the Life of Helical Spring Systems
Abstract: Helical springs are essential mechanical factors considerably employed in automotive, aerospace, and artificial systems because of their capability to store and release energy, absorb shock, and sustain repeated weight cycles. The performance, responsibility, and durability of these springs play a vital part in ensuring the effectiveness and safety of the entire system in which they are integrated. Over time, numerous researchers have focused on strategies to enhance the service life …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 12–24 Read article
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Engineering of PEG-b-PCL/Pluronic F127 Polymeric Composite Micelles for Controlled Co-Delivery of Docetaxel and Curcumin in Prostate Cancer Therapy
Abstract: Polymeric composite nanocarriers made from amphiphilic block copolymers are popular for their customisable architecture, self-assembly behaviour, and drug release control. A PEG-b-PCL/Pluronic F127 micellar composite was developed and tested as a multifunctional nanocarrier for docetaxel and curcumin administration.The amphiphilic block copolymers Pluronic® F127 and PEG-b-PCL were employed to generate polymeric micelles using solvent evaporation-assisted self-assembly. The optimised polymer composite showed good colloidal stability and uniform size distribution with a zeta …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 Read article