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117 articles for “In silico study”
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Valeton Phytoconstituents from Curcuma Phaeocaulis as Prion Protein Mutant V210I Inhibitors: A Computational Docking and Virtual Screening Study
Abstract: Objective: Creutzfeldt-Jakob disease (CJD), a neurological disorder that is sporadic, fatal, communicable, and worsens rapidly, is caused by abnormal folding of prion proteins. Identifying and assessing the potential of phytocompounds from the Curcuma phaeocaulis Valeton plant as a new therapeutic candidate aimed at the treatment of CJD is the objective of this research article. Methods: In this experiment, we assessed outcomes following an in-silico assessment to design a new oral …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 2, 2023 · pp. 1–16 Read article
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Technometric Portrait of Sri Vinod Dham, an Indo-US Engineer, Father of Intel Pentium Process: A Quantitative Analysis
Abstract: Vinod Dham is recognized as the ‘Father of Pentium Chip’ or ‘Father of Intel Pentium Process’ in the field of the computer industry, and as an Indo-American pioneer from Silicon Valley. He has contributed 10 research papers during 1982–1986, with an average of two papers per year. This study tries to analyze his contributions through a bibliometric study and draw his familiarity as a world-famous electronic technologist. Data has been …
Published in Research & Reviews : Journal of Statistics · Vol. 14, Issue 3, 2025 · pp. 16–25 Read article
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Multi Objective Optimization of Aluminium (AA6061-SiC-Flyash) Metal Matrix Composites using TOPSIS Method
Abstract: Metal Matrix Composites (MMCs) have significant interest due to their superior mechanical properties, including improved strength, hardness, and fracture resistance. This study investigates the optimization of the mechanical and fracture behaviour of casted AA6061-SiC-Fly Ash (FA) MMCs using the TOPSIS method. Silicon carbide(SiC) and fly ash (FA) reinforcements, with different weight percentages of 5%, 10%, and 15% were fabricated through sand casting method. Total 10 combinations of composites are prepared …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 459–469 Read article
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Comparative Study of Symmetric and Asymmetric Oxide Double Gate Junction less FET
Abstract: we carry out the performance of symmetric oxide (HfO2+HfO2) and asymmetric oxide (SiO2+HfO2) n-type junction less field-effect transistor (JLFET) based on two- dimensional Poisson equation. This study is accomplished by simulating a symmetric and asymmetric double gate JLFET on Sentaurus, Technology Computer Aided Design (TCAD) simulator for Silicon (Si) material at room temperature and varying temperature in between 300-360 k. Based on device simulation we find that the asymmetric oxide …
Published in Journal of Semiconductor Devices and Circuits Read article
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Silicon Symphony: The Science of Semiconductors Circuits
Abstract: Modern electronics are built on the foundation of semiconductor circuits, which precisely and efficiently control the flow of electrical impulses. This article takes a look at the underlying physics of semiconductor materials and how their unique electrical properties allow the design and functioning of diodes, transistors and integrated circuits. This study links microscopic scientific principles to the behaviour of real circuits. It considers essential concepts such as charge carriers, doping …
Published in International Journal of Solid State Innovations & Research · Vol. 4, Issue 1, 2026 Read article
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In silico analysis of Abrus precatorius L. as a potential agonist of PPARγ : A novel approach to the treatment of diabetes
Abstract: Diabetes mellitus is a chronic disorder that is characterized by a lack of insulin secretion by the pancreas or a defect in insulin action, or both. If diabetes is not controlled, over time it can cause damage to blood vessels and nerves, leading to life-threatening complications such as, kidney damage, heart disease and vision impairment. It can also weaken the immune system, making patients more prone to infection. Although treatments …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
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Wear and Tribological Characteristics of Novel Metal Matrix Composites
Abstract: The development of advanced metal matrix composites (MMCs) with enhanced tribological performance has become increasingly important due to the premature failure of critical engineering components operating under severe wear conditions in automotive, aerospace, marine, defense, and power generation systems. Conventional composites such as Copper–Alumina and Aluminium–Silicon Carbide have demonstrated improved mechanical and wear characteristics; however, their widespread application is often limited by issues including particle agglomeration, non-uniform reinforcement distribution, porosity …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1326–1346 Read article
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Development of a Self-Cleaning Mechanism for Solar Panels to Enhance Efficiency
Abstract: On Earth, solar energy is the most plentiful source of energy. As it happens, the heat generated by the fusion of helium on the outermost part of the Sun additionally happens to be renewable. This energy is becoming popular because of natural advantages. In digital circuit design, AI can aid in logic synthesis and analog circuit design, AI can help in sizing transistors. The tools used to transform daylight into …
Published in Journal of Mechatronics and Automation · Vol. 11, Issue 1, 2024 · pp. 1–10 Read article
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First Insights into Whole Genome Sequencing of the Mycobacterium tuberculosis Complex: Molecular Diversity and Drug Susceptibility Patterns in Senegal
Abstract: Background: We conducted a bibliographic analysis of the Mycobacterium tuberculosis complex (MTBC) in sub-Saharan Africa, which included the analysis of 8,139 genomic sequences from 34 of the 49 sub-Saharan African countries. Notably, only one complete sequence from Senegal was identified, which had been generated in the United States. Our primary objective was to utilize whole genome sequencing (WGS) to detect resistance in anti-tuberculous strains of the MTBC in Senegal. This …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
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Influence of Aspect Ratio on the Mechanical and Tribological Properties of Vertical Centrifugal Cast Aluminium Silicon Alloy
Abstract: To get a sound cast of precise shape and size in the vertical centrifugal casting process, the flow behavior of the melt and process parameters such as aspect ratio of the mould, rotating speed, volume fraction, etc. must be optimized. The optimal parameters of the vertical centrifugal casting process derived from past cold modelling studies in casting of Al-12%Si alloy are investigated in this paper. Casts were obtained using 7 …
Published in Journal of Polymer & Composites · Vol. 11, Issue 13, 2023 · pp. 104–111 Read article
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An Experimental Investigation of Process Parameters for Aluminum Alloy Composites
Abstract: The objectives of this work are to develop an aluminum alloy composites and investigate machining process parameters effect on the tool wear rate for composites. The composite is enhanced using silicon carbide and graphite. The composite is made by a method called stir casting. Furthermore, it is investigated both mathematically and experimentally. This study takes trial on aluminum alloy composite to see output characteristics tool wear rate are affected by …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 185–193 Read article
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Exploring Phytochemicals from Ricinus Communis for Potential Therapeutic Applications in Rheumatoid Arthritis: An in-Silico Approach
Abstract: Aim: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by the immune system mistakenly attacking the joints, leading to swelling, discomfort, and joint deformities. Current management strategies include anti-rheumatic drugs and biologics, which have limitations. This study aims to explore the therapeutic potential of Ricinus communis (castor bean plant) phytochemicals as plant-based therapies for autoimmune conditions, like RA. Methods: Phytochemicals from Ricinus communis were retrieved using the IMPPAT database, …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 32–41 Read article
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TiO₂ Nanostructured Material-based Gas Sensor for Detecting Oxygen and LPG Gases
Abstract: This Paper investigates the use of TiO2 nanowires and nanotetrapods on glass and silicon substrates for sensing combustible gases such as LPG (Liquid Petroleum Gas) and Oxygen. The growth of Titanium dioxide (TiO2) nanowires/nanorods/nanotetrapods was investigated using both physical and chemical methods. In thermal evaporation method, both with and without vacuum conditions, was employed to synthesize various TiO2 nanostructures. A vacuum coating machine was utilized to create uniform TiO2 thin …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 443–451 Read article
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Needle Choice in Spinal Anaesthesia: Is the 25-Gauge Whitacre Superior to the Quincke in Reducing Post-Dural Puncture Headache
Abstract: The process known as endotracheal intubation involves inserting a synthetic tube into the trachea and inflating the former's cuff to create an airtight seal. Of all the specialised masks in the LMA family, the PLMA is the most intricate. The cuff, the airway tube, the drain (gastric access) tube, and the inflation line with pilot balloon are its four primary components. This drain tube aids in identifying mask malposition and …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 2, 2025 Read article
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Needle Choice in Spinal Anesthesia: Is the 25-Gauge Whitacre Superior to the Quincke in Reducing Post-Dural Puncture Headache
Abstract: The process known as endotracheal intubation involves inserting a synthetic tube into the trachea and inflating the former’s cuff to create an airtight seal. Of all the specialized masks in the LMA family, the PLMA is the most intricate. The cuff, the airway tube, the drain (gastric access) tube, and the inflation line with pilot balloon are their four primary components. This drain tube aids in identifying mask malposition and …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 2, 2025 · pp. 22–30 Read article
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Enhancement of the Life of Helical Spring Systems
Abstract: Helical springs are essential mechanical factors considerably employed in automotive, aerospace, and artificial systems because of their capability to store and release energy, absorb shock, and sustain repeated weight cycles. The performance, responsibility, and durability of these springs play a vital part in ensuring the effectiveness and safety of the entire system in which they are integrated. Over time, numerous researchers have focused on strategies to enhance the service life …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 12–24 Read article
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In silico Molecular Docking Analysis of Stephania glabra phytocompounds Targeting Thymidylate Kinase for potential Antituberculosis Activity
Abstract: Tuberculosis (TB) is an infectious disease caused by the bacteria Mycobacterium tuberculosis. It mainly affects the lungs and spreads through the air when a person with active TB in their lungs coughs, sneezes, or spits. This study investigates several bioactive compounds derived from plants to forecast how effective plant-based ligands will be at preventing tuberculosis. The purpose of the study was to use computational techniques to assess the effectiveness of …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
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A Review on Life Cycle Assessment of Solar Photovoltaic Electricity Generation Systems
Abstract: A popular system for calculating the environmental effects of energy systems from conception to death is life cycle assessment, or LCA. As a low-carbon generation technology, solar photovoltaic (PV) systems have fast spread throughout the world. The various PV technologies (monocrystalline, polycrystalline, thin-film), system scales (residential, commercial, utility), industrial locations, balance of system (BOS) configurations, and end-of-life (EoL) scenarios are all covered in this review of published life cycle assessment …
Published in Journal of Control & Instrumentation · Vol. 17, Issue 1, 2026 · pp. 1–6 Read article
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Evaluating Andrographis paniculata Phytochemicals as Potential Glioma Therapeutics via Molecular Docking Approach
Abstract: Evaluating Andrographis paniculata Phytochemicals as Potential Glioma Therapeutics via Molecular Docking ApproachGlioneuronal tumors and gliomas are grade I tumors classified by the World Health Organization (WHO). They typically grow slowly and primarily affect infants, children, and teenagers, but can also occur in adults. They mostly cause seizures caused by gangliomas. Most current treatments include surgery and radiotherapy. Since this disease affects children, the current treatments may cause complications. Andrographis paniculata …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 82–93 Read article
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Stretchable Elastomer–PCM Composites with Bluetooth-Enabled Temperature Monitoring for Wearable Healthcare IoT Devices
Abstract: The rapid advancement of wearable healthcare technologies has created a growing demand for multifunctional polymer composites capable of simultaneously providing mechanical flexibility, thermal energy management, electrical conductivity, sensing capability, and wireless communication. In this study, a stretchable elastomer-based polymer composite integrated with a phase-change material and a Bluetooth Low Energy temperature monitoring system was developed for wearable healthcare Internet-of-Things applications. The polymer composite was fabricated using an Ecoflex silicone elastomer …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 241–257 Read article