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480 articles for “Drug Delivery”
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A Comprehensive Review on Buccal Drug Delivery System
Abstract: Buccal delivery involves the running of the desired drug through the buccal mucosal membrane lining of the oral cavity. The buccal region of the oral cavity is a striking target for administration of the drug of choice because it offers some discrete advantages over all other routes. However, the mucosal lining of the oral cavity drugs which undergo rigorous firstpass metabolism, for those drugs, buccal route are excellent. Buccal drug …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 8, Issue 2, 2017 · pp. 20–32 Read article
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Innovations in Oral Drug Delivery: Challenges and Opportunities
Abstract: The advancement of novel drug manufacturing technologies offers immense opportunities for innovation but brings regulatory complexities that must be addressed to ensure successful implementation. Early and frequent collaboration with the FDA is fundamental for overcoming these challenges. The establishment of the FDA’s Emerging Technology Team has been pivotal in fostering open dialogue, brainstorming, and feedback between regulators and innovators, reducing the likelihood of unexpected setbacks that could jeopardize projects. Mechanisms …
Published in Trends in Drug Delivery · Vol. 12, Issue 1, 2025 · pp. 31–43 Read article
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A Review of basic Concept of Specific Drug Delivery System
Abstract: ABSTRACTThis review focus going on targeted drug delivery via Nanoparticles as a Special composition that couple a receptor site to a Nanosized , drug-loaded transporter as a budding means to get improved effectiveness of a drug at the site of significance. The conception of targeted drugs is not new, but since to 1906 while Ehrlich initial postulate the ‘magic bullet’. therefore is must to build up a appropriate drug system …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 13, Issue 3, 2022 · pp. 21–26 Read article
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Novel Synthesis of Encapsulated Super Paramagnetic Iron Nanoparticles (Fe3O4) and its Evaluation in Drug Delivery System
Abstract: Nanoparticles can be defined as solid, submicron, colloidal particles ranging in size from 10–100 nm in diameter, generally but not necessarily made of natural or synthetic polymers, in which drugs can be adsorbed, entrapped, that exhibit new or enhanced size-dependent properties as compared to microparticles. Iron oxide nanoparticles are often magnetic by nature, which means that they obey Coulomb’s law, and can be manipulated by an external magnetic field gradient. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 7, Issue 2, 2016 · pp. 11–24 Read article
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Concentration of Surfactant in Microemulsions as Novel Drug Delivery Systems
Abstract: Microemulsions are clear, stable, isotropic thermodynamically stable systems mixtures of oil, water and ,surfactant frequently in combination with a cosurfactant. Microemulsion system has acceptable potential to act as a drug delivery vehicle by putting a wide range of drug molecules. It has most effective advantage like excellent thermodynamic stability, high drug solubilization capacity, improved oral bioavailability and protection against enzymatic hydrolysis. Surfactant based chemical systems have been reported in many …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 2, 2020 · pp. 8–15 Read article
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Microsphere: A Novel Drug Delivery System Approach
Abstract: Microspheres are the multiarticulate novel drug delivery dosage form, it contains the particle size range from 1 to 50 µ and characteristically spherical in shape with free flow property. It is widely known as “Microparticles”. Microspheres are prepared by covering the drug particles with polymeric solution (obtained in natural, semisynthetic or synthetic form) to achieve controlled release of drug, which produces prolonged action with reduced toxicity at the specified site …
Published in Trends in Drug Delivery · Vol. 6, Issue 1, 2019 · pp. 24–30 Read article
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Enhancing Peptic Ulcer Therapy: Innovations in Mucoadhesive Drug Delivery
Abstract: Peptic ulcer disease is still a sincere gastrointestinal demand makes medication administration difficult because of the harsh and changing stomach environment. This paper investigates the potential of using mucoadhesive drug delivery devices to improve the accuracy and effectiveness of peptic ulcer therapies. Due to the inherent characteristics of mucoadhesive drug delivery systems, localized and sustained drug release is made possible by their extended contact and adherence to the gastrointestinal tract's …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 62–76 Read article
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Formulation and Characterization of Mesoporous Nanoparticulate Drug Delivery Platform
Abstract: The aim of this study was to synthesize and characterize mesoporous silica nanoparticles, namely, SBA-15 (Santa Barbara Amorphous) and MCM-41 (Mobile Crystalline Material) as a drug delivery platform. These MSNs have been synthesized using triblock copolymer F 127, cetyl trimethyl ammonium bromide (CTAB) as a co-surfactant and tetraethyl orthosilicate (TEOS) as a silica precursor. The synthesized MSNs were characterized by scanning electron microscopy (SEM), powder X-ray diffraction (PXRD), particle size …
Published in Trends in Drug Delivery · Vol. 2, Issue 1, 2015 · pp. 21–27 Read article
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Sublingual Drug Delivery System: An Update
Abstract: Oral transmucosal delivery, especially sublingual delivery, has progressed far beyond the use of traditional dosage forms with novel approaches emerging continuously. Drug delivery via the oral mucous membrane is considered to be a promising alternative to the oral route, offering a vast number of advantages. Sublingual delivery tends to administer substance via mouth in such a way that the substance is rapidly absorbed via blood vessels under tongue, bypassing the …
Published in Trends in Drug Delivery · Vol. 3, Issue 3, 2016 · pp. 1–19 Read article
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Development and Characterization of Selfnanoemulsifying Drug Delivery System
Abstract: AbstractNanotechnology has presented a novel perception of human knowledge and led to innovation in the field of biological sciences including diagnostics, food, drug delivery, biomaterials for implants or prostheses, and the production of biomimetics appropriate for applications in the field of medicine. With their pinpoint accuracy and minuscule size, nanomaterials is rising in importance. Nanoscale formulations have a size range of 100–10,000 times lesser than that of the cell of …
Published in Trends in Drug Delivery · Vol. 9, Issue 3, 2022 · pp. 1–18 Read article
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Nano-Therapeutics in Diabetes Mellitus: Revolutionizing Diagnosis, Treatment, and Drug Delivery
Abstract: Diabetes mellitus is a chronic metabolic disorder in which blood glucose concentration remains high over an extended duration, resulting in significant lethal complications, including neuropathy, nephropathy and cardiovascular diseases. However, conventional diabetes management strategies, including insulin therapy and oral hypoglycemic agents, rarely exhibit poor bioavailability, high doses, off target delivery, etc. Nanotechnology has brought the rise of diabetes treatment revolution, by overcoming the challenges present in standard treatment, owing to …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 08–19 Read article
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Review of Advanced Drug Delivery System: Nanotechnology
Abstract: Nanotechnology is the science and technology conducted at nanoscale, i.e., 1–100 nm. It is the manipulation of matter with at least one dimension ranging from 1–100 nm.In this study, we discussed the importance of nanoparticles/nanotechnology for drug delivery, their characteristics, applications and future of nanotechnology. Nanoparticles are very small fascinating little objects. It deals with physics quantum mechanics (theory in physics which describes nature at smallest scale of energy levels). …
Published in Trends in Drug Delivery · Vol. 5, Issue 2, 2018 · pp. 23–26 Read article
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Flaxseed-Based Drug Delivery Systems: Advancing Colon Cancer Treatment
Abstract: Flaxseed (Linum usitatissimum) has long been appreciated for its rich nutritional profile, including essential fatty acids (such as α-linolenic acid), plant fibers, and lignans. Recent research has focused on its potential as a novel drug delivery system (DDS) for the treatment of colon cancer. This review explores the bioactive constituents of flaxseed, their pharmacological activities, and innovative approaches to the use of flaxseed extracts in drug delivery for the treatment …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 54–59 Read article
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Ocular Drug Delivery System: Challenges and Opportunities
Abstract: Eye is most sensitive organ of body which is highly protected to prevent entry of any exogenous substance. This defence mechanism of eye renders the development of ocular drug delivery system as the challenging task to ophthalmic formulation scientist. Knowledge of anatomy, physiology and barriers for transportation of drug at different target site of eye is essential to develop successful ocular formulation. Topical administration of drug in the form of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 9, Issue 3, 2018 · pp. 14–30 Read article
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Innovative 3D Printed Cell Scaffolds with Magnetized Nanocomposites for Targeted Cancer Therapy Drug Delivery
Abstract: In recent years, scaffolds have gained increasing attention in the field of tissue engineering, especially in cancer treatment. Nanocomposite scaffolds have emerged as promising candidates for delivering drugs to cancer cells. 3D printing technology has enabled the fabrication of customized scaffolds with precise pore size and complex geometries. This study explores the development of 3D printed scaffolds of nanostructured made of graphene oxide and Poly-Caprolactone (PCL) nanocomposites, which can be …
Published in Journal of Polymer & Composites · Vol. 11, Issue 3, 2023 · pp. 48–55 Read article
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RNA- Based Drug Delivery, Current Advances, Pharmaceutical Applications, and Future Perspectives
Abstract: RNA-based therapeutics have emerged as a transformative approach in modern medicine due to their ability to regulate gene expression with high specificity and precision. Advances in molecular biology, RNA chemistry, and nanotechnology have accelerated the development of diverse RNA modalities, including messenger RNA (mRNA), small interfering RNA (siRNA), microRNA (miRNA), antisense oligonucleotides (ASOs), and RNA aptamers. These therapeutics offer promising strategies for the treatment of cancer, genetic disorders, infectious diseases, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 · pp. 27–41 Read article
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Application of Drug Delivery using Nano- technology to Cure Mental Disorders (Schizophrenia)
Abstract: Nanotechnology involves the manipulation of the count at an atomic scale to create novel systems, materials, and devices. This groundbreaking era holds substantial potential for scientific development across various domain names, which includes manufacturing, patron items, electricity, substances, and remedies. In current times, the sphere of prescribed drugs has witnessed a brilliant surge in the usage of nanotechnology for the improvement of revolutionary medications. Schizophrenia, a neuropsychiatric disorder affecting the …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 1, 2024 · pp. 51–65 Read article
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Using Artificial Intelligence for The Design of Polymeric Drug Delivery Systems
Abstract: AI is cost effective and time efficient process. Artificial intelligence is a method which uses high speed calculation, the improvement regarding algorithm along with collection about biological and chemical features in pharmaceutical exploration and development .Present day because continuous progress towards machine learning (ML),Artificial intelligence an effective statistics analysing technology might have been broadly utilized in drug design .In pharmaceutical exploration and research employ of AI in target identification, compound …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 1018–1027 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Advanced Controlled Drug Delivery Systems
Abstract: Polymer-gel forms have gained popularity in medicine as means of medication delivery over the skin. This is so since they enable medications pass the skin more readily. These products allow medicine to be administered without surgery and provide continuous active ingredient supply. They are excellent for long-term therapy for managing conditions that keep resurfacing. From tiny synthetic ones to huge biological ones, polymer gels can store a wide spectrum of …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 271–284 Read article
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Synthetic and Natural Polymer Composites in Wound Healing and Drug Delivery
Abstract: Both man-made and natural polymer mixtures have become important materials in wound repair and medicine delivery because they can be used in many ways and work well with living things. The benefits of both man-made and natural polymers are combined in these composites. They have a wide range of mechanical, chemical, and biological qualities that make them useful for many medical uses. In wound healing, polymer mixtures help tissues grow …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 466–478 Read article