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125 articles for “Dosage”
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Design and Assessment of Fixed Dose Combination Containing Fenofibrate and Pravastatin Sodium in Tablet Formulation: A Bioinformatics Approach
Abstract: The aim of this is study is to formulate and evaluate fixed dose combination of Fenofibrate and Pravastatin sodium in tablet dosage for the treatment of Dyslipidemia. For the formulation and optimization of fenofibrate layer, two factor three level factorial design was used as experimental design for optimization with a minimum of nine run. All the nine trial (F1–F9) has been formulated according to the experimental design by wet granulation …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 1, 2024 · pp. 1–20 Read article
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An in-silico toxicity study of the phytocompounds found in Pongamia pinnata leaves using the ProTox-II web server
Abstract: The aim of the current study was to determine the Insilco toxicity of the phytocompound present in the leaves of Pongamia pinnata. The leaves of Pongamia pinnata have long been used in traditional medicine for their therapeutic properties. Nowadays, herbal toxicity is a common problem caused by incorrect dosage. The FDA reviews the safety and effectiveness of herbal products only in response to patient or health care provider complaints—problems with …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 13, Issue 1, 2024 Read article
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UV Method of Development and Validation of Olaparib
Abstract: An analytical method must be developed and validated in the discovery, development, and production of pharmaceuticals to ensure the identification, purity, potency, and performance of drug commodities. Quality control laboratories use official test protocols that emerge from the processes. A simple ultraviolet spectrophotometric approach was designed and validated using various characteristics, including linearity. Precision, reproducibility, accuracy, robustness, ruggedness, limit of detection, and limit of quantification are among the measuring criteria. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 20–27 Read article
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Utilization of Recron Fibers for Improving Subgrade Stability of Expansive Soils
Abstract: The major interest in the utilization of synthetic fibers is used as reinforcing material for developing reinforcing effect into the entire soil composition laid bellow the structures whare as construction works are going on. Various articles are published on soil reinforcement, yet some of them fibers used are prepared by using with synthetic materials, one type of synthetic fibers were Recron fiber it is used as a reinforcing element to …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 170–178 Read article
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Evaluation of Lemon Grass (Cymbopogon Citratus) Performance for Petroleum Hydrocarbon Degradation in Soil Environment
Abstract: The evaluation of lemon grass (cymbopogon citratus) performance for petroleum hydrocarbon degradation in soil environment was monitored with respect to contact time or period of exposure. Models were developed in this research to demonstrate the potential of the first-order kinetic, Michaelis Menten and the LineWeaver Burk Plot, and the evaluation of the effect of the biostimulant dosage was monitored in accordance the total petroleum hydrocarbon degradation. The performance of lemon …
Published in Journal of Catalyst & Catalysis · Vol. 11, Issue 1, 2024 · pp. 33–49 Read article
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Phyto Biotics in Aquaculture
Abstract: This paper aims to assess the existing knowledge on the use and effects of phytobiotics in fish farming, as well as their potential for broader application in aquaculture. With the rising demand for fish, there has been a noticeable decline in fish production in recent years, which could be a driving factor behind the increasing interest in using phytobiotics in this field. The main factor contributing to the decrease in …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 2, 2024 · pp. 18–22 Read article
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Oral Thin Films of Ondanetron Hcl: Formulation and Performance Evaluation
Abstract: This study had the goal to formulate oral polymeric thin film that would dissolve and disintegrate instantly, while also having high mechanical features. These are the most advanced forms of solid dosage forms. Solvent casting was the technique employed to create oral thin films. These are additionally referred to as buccal films/strip, mouth dissolving films, oral thin films, as well as oral strips of paper. These films are suitable for …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 1–6 Read article
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To Investigate Hormonal Fluctuations in Male Rattus norvegicus after Treatment with 50% Methanolic Extract of Acacia arabica
Abstract: The use of medicinal plants in traditional and modern medicine has garnered significant interest for their therapeutic potential. Acacia arabica, commonly known as babul, is renowned for its bioactive compounds and diverse pharmacological properties. This study investigates the hormonal fluctuations induced by 50% methanolic extract of Acacia arabica in male Rattus norvegicus, aiming to explore its potential as a male contraceptive. Male contraception remains limited primarily to condoms and vasectomy, …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 3, 2024 · pp. 28–38 Read article
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Flaxseed and Diabetes Management: A Comprehensive Review of Recent Studies and Potential Mechanisms
Abstract: Diabetes mellitus, a condition characterized by chronic hyperglycemia, has become a significant global health challenge, leading to substantial morbidity and mortality rates. Dietary techniques are crucial for the effective control of diabetes, including both pharmaceutical and non-pharmacological therapies. Flaxseed (Linum usitatissimum) is one of the functional foods that has attracted a lot of interest because of its abundance of bioactive components, including lignans, dietary fiber, and alpha-linolenic acid (ALA). The …
Published in International Journal of Nutritions · Vol. 2, Issue 1, 2025 · pp. 24–32 Read article
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Geochemometric Assessment of Primordial Radionuclides and Trace Elements in Coastal Sediments: Environmental and Radiological Implications for South India
Abstract: This study focuses on environmental radioactivity and trace element contamination in coastal sediments along the southern region of the Indian subcontinent, from the Palar River to Pulicat Lake. Utilizing gamma-ray spectroscopy with a NaI (Tl) detector, along with atomic absorption spectroscopy, the research examines the spatial distribution and activity concentrations of primordial radionuclides—namely, 238U, 232Th, and 40K—as well as trace elements such as Ni, Pb, Mn, Zn, Cu, Co, Fe, …
Published in International Journal of Minerals · Vol. 1, Issue 1, 2024 · pp. 33–37 Read article
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Recent Advances & Prospects of Transferosomes for Transdermal Delivery: Trends in Drug Delivery
Abstract: There have been several non-invasive administrations that have emerged recently to replace conventional needle injections. With its minimal rejection rate, remarkable ease of administration, and remarkable patient comfort and perseverance, the transdermal drug delivery system (TDDS) is the most attractive of them all. The skincare industry, which includes cosmetics, may also find use for TDDS in addition to the pharmaceutical industry. As this strategy mainly entails local drug administration, it …
Published in Trends in Drug Delivery · Vol. 11, Issue 3, 2024 · pp. 01–21 Read article
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Environmental Impact of Chlorantraniliprole in Bell Peppers: Residue Dynamics and Sustainable Practices
Abstract: Bell peppers (Capsicum annuum) are integral to global agriculture and nutrition due to their rich nutrient profile and culinary uses. To protect these crops from pest infestations, Chlorantraniliprole, a widely employed insecticide, has gained prominence. This research investigates the environmental fate of Chlorantraniliprole in bell pepper ecosystems, emphasizing its effects on soil, water quality, and overall ecological health. The study employs a multifaceted approach, conducting field experiments in the Sangli …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 14, Issue 3, 2024 · pp. 1–7 Read article
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A Review on: Oral Thin Films: A New Approach to Effective and Easy Drug Delivery
Abstract: Oral Thin Film (OTF) is an advance drug delivery system in which drug is incorporated into dissolvable strip and place in oral cavity for rapid absorption. OTF is useful for patient such as pediatric and geriatric who have difficulty swallowing pills. It provides rapid action, precise dosage and improved bioavailability. OTFs consist of fast-dissolving films, extended-release films, and mucoadhesive films for various therapeutic applications. The manufacturing processes of OTFs such …
Published in Trends in Drug Delivery · Vol. 11, Issue 3, 2024 · pp. 22–41 Read article
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Recent Trends in Ocular Drug Delivery: Challenges and Approaches
Abstract: Drug topically regulation can be accessed most easily in the eye. When given topically as eye drops, medication ocular bioavailability is quite low. Drug entry into specific ocular locations is complicated by the complex anatomy and physiology of the human eye. Research has long been interested in the topical administration of successful treatments. To provide a suitable ocular penetration and extend the duration of drug residence is their challenging task. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 22–38 Read article
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Design and Development of Novel Floating Drug Delivery Systems
Abstract: Recent advances in science and technology have greatly aided in the creation of novel drug delivery methods, especially in addressing physiological issues including irregular stomach emptying times and brief stomach residence periods. Long-term stomach absorption is the goal of gastro-retentive dosage forms (GRDF). Floating drug delivery systems, expanding or swelling systems, polymer-based bioadhesive systems, high-density systems, and other ways that postpone stomach emptying are just a few of the techniques …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 1–22 Read article
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Eco-Friendly Tri-Layer Hybrid Composites: A Sustainable Approach to Polymer Matrix Materials
Abstract: In the current study, we explored the use of environmentally friendly natural fibers such as sisal, banana, and kevlar. These fibers were fabricated by hand lay-up technique, and their impact on tensile and dynamic properties was evaluated according to ASTM standards. The assessment was conducted under both dry and wet conditions, considering two different chemical dosage parameters for comparison. Additionally, the tri-layer fibers underwent two separate chemical treatments using 1% …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 195–205 Read article
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Biochemical Estimation of Allaxon Induced Hyperglycemia in Rats Treated with Polyherbal Preparation of Two of Indian Medicinal Plants Cordia Myxa and Canscora Diffusa
Abstract: A systematic study was conducted on extracts of Cordia myxa and Canscora diffusa to evaluate their qualitative chemical composition, phytochemical content, and antidiabetic activity. Then the Poly herbal extract is prepared with the selected plant powders, subjected to acute-toxicity studies for dose fixation. The herbal extracts formulation was prepared taking three selected dosages. The preparations are evaluated for anti-diabetic activity using Steptozotocine and Alloxan induced diabetic models in rats. The …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 52–60 Read article
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Using Artificial Intelligence for The Design of Polymeric Drug Delivery Systems
Abstract: AI is cost effective and time efficient process. Artificial intelligence is a method which uses high speed calculation, the improvement regarding algorithm along with collection about biological and chemical features in pharmaceutical exploration and development .Present day because continuous progress towards machine learning (ML),Artificial intelligence an effective statistics analysing technology might have been broadly utilized in drug design .In pharmaceutical exploration and research employ of AI in target identification, compound …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 1018–1027 Read article
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A Study to Assess the Prevalence of Self-medication and Its Associated Factors Among Pregnant Women in Selected Tertiary Care Teaching Hospital at Kuppam, Chittoor District, Andhra Pradesh
Abstract: Self-medication, the practice of using medications without a doctor's prescription, is a growing global public health issue, particularly in resource-limited settings. In pregnancy, self-medication can pose serious risks, including misdiagnosis, incorrect dosages, drug interactions, and prolonged use. This study aimed to assess the prevalence of self-medication, and the factors associated with it among pregnant women at a tertiary care teaching hospital in Kuppam, Chittoor district, Andhra Pradesh. A descriptive cross-sectional …
Published in International Journal of Midwifery Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 41–48 Read article
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Advancing Capsule Technology: A Comprehensive Review of Formulation Strategies
Abstract: Capsules are a popular and versatile oral dosage form used in drug delivery, offering benefits such as ease of swallowing, taste masking, and improved stability of active pharmaceutical ingredients (APIs). They can be made from gelatin or non-gelatin materials like Hydroxypropyl Methylcellulose (HPMC), Polyvinyl Alcohol (PVA), and starch, catering to dietary, cultural, and sustainability needs. Capsules can be engineered for controlled, sustained, or targeted release, enhancing bioavailability, particularly for poorly …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 44–56 Read article