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1968 articles for “rokitansky’s disease.”
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Prevention of Primary Hypertension Through Asbab-e-Sitta Zaruriya: A Therapeutic Paradigm
Abstract: Hypertension, defined as blood pressure elevation to a level that increases the risk of organ damage, Recent guidelines classify hypertension as systolic blood pressure ≥130 mmHg or diastolic blood pressure ≥80 mmHg, distinguishing between primary (essential) and secondary forms. It affects over one billion individuals globally and contributes to approximately 9.4 million deaths annually. Nearly 63% of total deaths in India are due to non-communicable diseases, of which 27% are …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 11, Issue 3, 2024 · pp. 13–20 Read article
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Liposomes as Therapeutic Vehicles: Advancing Targeted Drug Delivery in Healthcare
Abstract: Liposomes represent an innovative approach to targeted drug delivery. These tiny, lipid-based vesicles can encapsulate medications, allowing them to travel directly to diseased cells while minimizing impact on healthy tissues. By using liposomes, medications can improve their effectiveness while reducing side effects, leading to better overall treatment results.. Their structure enables a controlled release of the drug, which can be particularly beneficial for therapies requiring sustained action. This technology holds …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 39–46 Read article
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Artificial Intelligence in Drug Repurposing: A Short Impact Assessment
Abstract: Artificial intelligence (AI) in pharmaceutical repurposing has become a game-changing tool that opens new avenues for the application of new drugs that have already been approved. Traditional drug discovery is a lengthy and expensive process, whereas AI can rapidly analyze vast datasets of biological, chemical, and clinical information to predict drug-disease interactions. AI-driven techniques, such as machine learning, natural language processing, and deep learning, enable the identification of potential repurposing …
Published in Trends in Drug Delivery · Vol. 11, Issue 3, 2024 · pp. 42–45 Read article
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SiRNA-Based Multivalent Vaccines: A Systematic Review of Potential Risks, Benefits, and Future Applications
Abstract: Background: Small interfering RNA (SiRNA) technology represents a promising innovation in vaccine development, especially for multivalent vaccines that can target multiple pathogens or antigenic variants simultaneously. siRNA-based vaccines offer a unique mechanism to induce specific immune responses, presenting an adaptable and potentially powerful tool for tackling infectious diseases and cancer. Methods: This systematic review synthesizes recent studies on siRNA multivalent vaccines, focusing on their immunogenicity, safety, and effectiveness. We reviewed …
Published in International Journal of Vaccines · Vol. 2, Issue 1, 2025 · pp. 43–49 Read article
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Qualitative Detection of Active Compounds of Some Extracts: The Medicinal Plant
Abstract: This study aimed to prepare aqueous extracts of the seeds of the following plants (Apium, Coriandrum, Trigonella, Punica, Linum,, Cinnamon, and Ocimum) to detect the active compounds in them represented by (saponins, tannins, phenols, alkaloids, and glycosides). The study concluded that the presence of alkaloids in the extracts of Apium, Trigonella, Punica, and Ocimum, and their absence in the remaining extracts. Phenols were observed in the extracts of Trigonella, cinnamon, …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 14, Issue 3, 2024 · pp. 48–53 Read article
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Review of Current Trends in Vaccine Development against Zoonotic Viruses: Challenges and Innovations
Abstract: The emergence of zoonotic viruses poses a significant threat to global public health, necessitating rapid advancements in vaccine development. This review highlights the current trends and innovative strategies employed in the creation of vaccines against zoonotic pathogens, including but not limited to viruses responsible for diseases such as Ebola, Zika, Nipah, and more recently, SARS-CoV-2. We discuss various vaccine platforms, including inactivated, live attenuated, mRNA, and viral vector vaccines, focusing …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 1–11 Read article
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Gut Feelings: Unravelling the Secrets of the Microbial Universe Within
Abstract: The human digestive system hosts a varied and dynamic community of microorganisms, commonly known as the gut microbiota. This complex community, which includes various organisms such as bacteria, archaea, viruses, and fungi, is essential and important for numerous bodily functions such as metabolism, immune response, and cognitive development. The composition and vast diversity of the gut microbiome are shaped by diet, lifestyle, and genetic factors. Disruptions in this balance, known …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 3, 2024 · pp. 21–33 Read article
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Targeting TNFSF4 in the Management of Systemic Lupus Erythematosus
Abstract: Systemic lupus erythematosus (SLE) is a multifaceted autoimmune disorder that remains a significant challenge for both healthcare providers and researchers. Despite advances in understanding its mechanisms, finding effective therapies is still difficult. This review highlights a potential therapeutic target in SLE research: tumor necrosis factor superfamily member 4 (TNFSF4), also referred to as OX40L. We explore how TNFSF4 contributes to SLE development, looking at its role in immune system regulation …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 3, 2024 · pp. 6–14 Read article
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Lung Cancer Detection and Classification Using Deep Learning
Abstract: Lung cancer is a disease that can be effectively treated if detected early. Various technologies, such as magnetic resonance imaging, isotopes, X-rays, and computed tomography scans, are employed for diagnosis. One of the most crucial strategies in combating cancer is early detection, which greatly enhances a patient’s likelihood of survival; this is where artificial intelligence plays a significant role. The approach proposed in this study leverages historical medical data to …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 3, 2024 · pp. 11–17 Read article
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Exploring the Therapeutic Potential of Grapeseed Phytoconstituent Through Molecular Docking Analysis for Multiple System Atrophy Treatment
Abstract: Objective: Alpha-synuclein (α-Syn) aggregates are a common neurodegenerative disorder associated with Parkinson’s disease and multiple system atrophy (MSA). As a fruit that is extensively grown, grapes have several pharmacological advantages when it comes to reducing oxidative stress. Research has indicated that grape seed phytoconstituents have a major effect on α-Syn. The objective of this study is to inquire into the pharmacological characteristics and potential therapeutic applications of grape seed derivatives …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 14–26 Read article
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Microbial Symphony: Understanding Biochemical Pathways for Precision Medicine and Beyond
Abstract: The human microbiome, an intricate ecosystem of microorganisms inhabiting the body, is a key regulator of host biochemistry and physiology. This review delves into the complex biochemical pathways influenced by the microbiome, spotlighting critical metabolites like short-chain fatty acids, bile acids, and tryptophan derivatives, which impact immune regulation, energy metabolism, and neurobehavioral functions. By examining interactions between the microbiome and the host, including the influence of genetic factors and metabolite-driven …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 28–43 Read article
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Evaluation of Temporal Distribution of Recurrent Cholera Outbreak in Zambia.
Abstract: Background: Cholera cases in Zambia have been observed over a period without understanding the epidemiological cycles. The aim of the study was to evaluate the temporal distribution of recurrent cholera outbreak in Zambia from 1977 to 2019. Methods: Cholera case records of both sex and all ages were retrospectively analyzed. The primary source documents were reviewed including infectious diseases line list, notifiable diseases reports, Health Impact Assessment, District Health Impact …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 10–21 Read article
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A Review on The effect of Polycystic Ovary Syndrome on some Hormonal and Metabolic Disturbances in Women
Abstract: Polycystic ovary syndrome (PCOS) is a common hormonal condition that affects women of reproductive age. It usually begins to appear during adolescence. The ovaries produce an abnormal amount of "androgens", which are male sex hormones that are usually found in women in small quantities. Ovarian syndrome causes hormonal imbalances, irregular menstrual cycles, increased cysts in the ovaries, in addition to hair growth all over the body, acne, and pain in …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 1, 2025 · pp. 21–28 Read article
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A Study on the Prevalence and Causative Factors of Anemia in Patients Undergoing Maintenance Hemodialysis
Abstract: Anemia is a common and serious issue in individuals with chronic kidney disease (CKD) who are on maintenance hemodialysis (MHD), greatly affecting their overall health and quality of life (QoL). Despite advancements in treatment, anemia remains a challenging issue in this population. This study investigates the prevalence of anemia and identifies the contributing factors in CKD patients on MHD with the aim of enhancing clinical management strategies. This study focused …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 1, 2024 · pp. 73–89 Read article
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Recent Developments in Structural Genomics: Uncovering Cellular Functions
Abstract: Structural genomics has become a groundbreaking field for understanding cellular functions by revealing the three-dimensional structures of proteins and other biomolecules. This field combines advanced methods like X-ray crystallography, nuclear magnetic resonance spectroscopy, cryo-electron microscopy, and computational modeling to explore the molecular structure and behavior of cellular components. Recent advances have significantly accelerated the pace of structure determination, bolstered by high-throughput methods and artificial intelligence tools like AlphaFold. These developments …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 30–35 Read article
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Computational Approaches to Understanding Cellular Signaling Pathways
Abstract: Cellular signaling pathways are fundamental in regulating vital processes, such as cell growth, differentiation, and apoptosis. The intricate and interconnected nature of these signaling networks requires sophisticated methods for their analysis. Computational approaches, including mathematical modeling, network analysis, and machine learning, have revolutionized the way researchers analyze and simulate cellular signaling. This article provides a comprehensive overview of computational strategies employed to model signaling pathways, with a focus on integrating …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 8–13 Read article
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Exploring Malaria Fever (Vishama Jwara) Through an Ayurvedic Lens: A Comprehensive Review
Abstract: Malaria fever, known as Vishama Jwara in Ayurveda, is a significant global health challenge caused by the Plasmodium species transmitted via Anopheles mosquitoes. While conventional medicine has advanced in diagnosing and treating malaria, exploring it through the Ayurvedic perspective offers valuable insights into its holistic understanding and management. Ayurveda describes Vishama Jwara as a fever with irregular patterns, aligning with the cyclical febrile episodes seen in malaria. This review delves …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 3, 2024 · pp. 47–53 Read article
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Evidence-Based Ayurveda Approaches for the Rapid Management of Dyslipidemia
Abstract: Dyslipidemia is increasingly prevalent ain modern society, primarily resulting from imbalances in lifestyle and dietary habits. Elevated levels of triglycerides, however, are associated with an increased risk of cardiovascular diseases and metabolic disorders. Ayurveda, the traditional Indian system of medicine, offers holistic approaches to managing lipid imbalances through dietary regulation, herbal formulations. While it may not directly correspond to a specific disease entity in Ayurveda, it is typically associated with …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 3, 2024 · pp. 63–66 Read article
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A Comprehensive review on phytomedicinal activity of chirchita (Achyranthes aspera): an Indian Rural Medicinal Plant
Abstract: Because it is used to treat many types of diseases. Native to India, Achyranthes aspera (Chirchita) has been used in rural medicine for generations.This review explores the phytomedicinal significance of Achyranthes aspera, focusing on its bioactive compounds and the pharmacological activities that support its use in treating various ailments. This plant is a useful tool in traditional and alternative medicine. Because it has anti-inflammatory properties Antioxidants Antibacterial, anticancer and liver …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 74–85 Read article
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Ethnopharmacological Insights: Uncovering Plant-Based Neuroprotective Treatments for Neurodegenerative Disorders
Abstract: The development of plant-based therapies for neurodegenerative diseases holds significant promise due to the therapeutic potential of natural compounds, such as Laurus nobilis, Aronia melanocarpa, and celastrol. This review identifies critical literature gaps in the current research, including inconsistent extraction methods, lack of clinical trials, insufficient documentation of long-term effects, limited mechanistic insights, and poor bioavailability. Addressing these gaps through standardization, rigorous clinical trials, advanced delivery systems, and comprehensive ethnopharmacological …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 13–18 Read article