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874 articles for “tries”
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Pathways in Drug Discovery and Development: From Molecular Targets to Market Approval
Abstract: A complicated, multidisciplinary, and resource-intensive process, the discovery and development of new pharmacological drugs is essential to the advancement of contemporary medicine. Finding and optimising lead chemicals comes after a disease-relevant biological target has been identified and validated. Through preclinical research in animal models, these leads are thoroughly assessed for toxicity, pharmacokinetics, safety, and efficacy. Clinical trials, which are carried out in several stages to evaluate safety, efficacy, ideal dosage, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 1, 2026 · pp. 01–04 Read article
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E-Commerce Study Using AR/VR and Ethical Convergence of Commerce
Abstract: The landscape of E-commerce is undergoing a fundamental transformation, shifting from a platform-centric model of transactional exchange to an immersive, ecosystem-driven experience. This analysis examines the critical trends and disruptive forces that define the immediate and long-term trajectory of digital commerce. The study identifies three foundational pillars driving future growth: Hyper-Personalization via Generative AI, Spatial Commerce (AR/VR Integration), and Sustainable Supply Chain Resilience. Future E-commerce will be characterized by the …
Published in E-Commerce for Future & Trends · Vol. 12, Issue 3, 2025 · pp. 20–26 Read article
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An Experimental Investigation of Polyethylene Terephthalate Fibers in the Properties of Concrete
Abstract: In India near about every year 45 million tons of solid waste is generated. The solid waste rate is increasing of 1.5 to 2% every year. In that total solid waste, Plastics contains 12.3% waste generated in which most common are the water bottles. Now the present worldwide situation, the production of PET (Polyethylene Terephthalate) exceeds 6.9 million tons per year. So that it is necessary to reusing of PET …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 1063–1072 Read article
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Pharmacological Comparison of Turmeric and Non-Steroidal Anti-Inflammatory Drugs in Pain Relief
Abstract: Pain is one of the most frequently encountered clinical symptoms affecting millions globally and is typically treated pharmacologically with nonsteroidal anti-inflammatory drugs (NSAIDs). However, long-term use of NSAIDs is associated with adverse effects such as gastrointestinal, renal, and cardiovascular issues. In recent years, turmeric and its main active compound, curcumin, have received considerable attention for their reported anti-inflammatory, analgesic, and antioxidant properties as natural therapeutic options. This review seeks to …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 1, 2026 · pp. 19–28 Read article
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Immune Dysregulation and Cytokine Circuitry in Genital Endometriosis: Mechanistic Insights and Next-Generation Immunotherapeutic Strategies
Abstract: Genital endometriosis is increasingly recognized as an immune-mediated inflammatory disorder driven by complex interactions between dysregulated immune cells, cytokine hubs, and microbiome-derived modulators. This review introduces a novel “immune–cytokine circuitry” framework that unifies innate and adaptive immune abnormalities with key cytokine loops sustaining chronic inflammation, angiogenesis, neuroinflammation, and immune tolerance. Within this circuitry, macrophage polarization, dendritic cell immaturity, NK-cell anergy, Treg expansion, Th17 amplification, and B-cell–mediated autoimmunity converge to establish …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 06–16 Read article
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Unlocking Novel Drug Targets and Therapeutic Advancements Against RNA Viruses: Insights from HMPV and SARS-CoV-2
Abstract: Re-emerging RNA viruses pose a significant epidemiological welfare threat due to their high mutation rates, potential for zoonotic transmission, and capacity to cause widespread outbreaks such as Human Metapneumovirus (HMPV), Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Influenza, etc. The rapid evolution and re-emergence of these viruses necessitate the development of novel drug targets and therapeutic strategies to combat existing and future outbreaks. This study focuses on structural as well …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 3, 2025 · pp. 54–86 Read article
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Preparation of Vitamin B12-Enriched Curds: A Novel Approach to Address Nutritional Deficiency in Vegetarian Populations
Abstract: Addressing the significant public health challenge of Vitamin B12 deficiency, particularly within India’s substantial vegetarian population (estimated at 35%), this study explored biofortification of the widely consumed dairy product curd (dahi) as a culturally acceptable solution, overcoming barriers of cost, access, and compliance associated with traditional supplements. Researchers isolated bacterial strains from Swiss cheese, presumptively identified as Propionibacterium shermanii based on phenotypic characteristics, and used them to ferment curd under …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 1, 2026 · pp. 1–15 Read article
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Configuration and Properties of Group III Elements in the Periodic Table
Abstract: Group III elements comprise those found in the third column of the periodic table, including boron, aluminum, gallium, indium, and thallium. These elements possess three valence electrons in their outermost shell, characterized by the electron configuration ns2np1, which influences their location and characteristics within the periodic table. The distribution of electron pairs, formal charges, oxidation states, and molecular morphologies of Group III elements and their compounds are illustrated in this …
Published in Journal of Materials & Metallurgical Engineering · Vol. 15, Issue 2, 2025 · pp. 23–30 Read article
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Integrating Ayurveda in Infertility Management: A Case Study on Fimbrial Blockage
Abstract: Infertility significantly impacts a woman’s psychological and physical health, as well as that of her family. Fallopian tube blockage is one of the leading causes of female infertility, accounting for a substantial number of cases globally. Conventional medical approaches, including in vitro fertilization (IVF) and surgical procedures, often present barriers due to their high cost, invasive nature, and limited accessibility. Additionally, cultural, financial, and personal considerations can further restrict their …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 3, 2025 · pp. 12–19 Read article
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Entropy, Symmetry, and Data Fusion: Emerging Methods in Multi-Objective Decision- Making and Smart Systems
Abstract: In the era of intelligent technologies and data-driven systems, multi-objective decision-making (MODM) has become an essential aspect of managing complex environments such as smart cities, autonomous systems, and cyber-physical networks. As decision-making scenarios become increasingly dynamic and uncertain, there is a growing need for advanced methodologies that can handle diverse objectives, conflicting constraints, and incomplete information. This review highlights the emerging role of entropy, symmetry, and data fusion as foundational …
Published in Emerging Trends in Symmetry · Vol. 1, Issue 2, 2025 · pp. 44–49 Read article
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Kinetics of Crystallization and Microstructural Evolution of Commercial Fluorophlogopite Machinable Glass- Ceramics in the System SrO∙4MgO∙Al2O3∙ 6SiO2∙2MgF2 with Varying in B2O3
Abstract: Glass materials based on fluorophlogopite stoichiometry with varying concentrations of B₂O₃ were synthesized using the melt-casting method, followed by heat treatment at different crystallization temperatures. The resulting glass and glass–ceramic samples were characterized using differential thermal analysis (DTA), scanning electron microscopy (SEM), X-ray diffraction (XRD), and Fourier-transform infrared (FT-IR) spectroscopy. Kinetic analysis revealed that the activation energies required for the formation of glass–ceramics were 192.77 kJ mol⁻¹ and 210.47 kJ …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 3, 2025 · pp. 1–16 Read article
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Evaluation of Organic-Mineral Fertilizer Components: A Multi-Criteria Analysis Based on Various Factors
Abstract: This study explores the potential of organic-mineral fertilizers as sustainable alternatives to synthetic options, evaluating ten such fertilizers, including coffee grounds, poultry eggshells, bone meal, Fish Emulsion, compost, cow manure, wood ash, biochar, seaweed extract, and green manure. A multi-criteria analysis assessed factors like effectiveness, cost, environmental impact, availability, and waste potential. Coffee grounds and poultry eggshells performed best due to their high nutrient content and positive soil effects, with …
Published in International Journal of Trends in Horticulture · Vol. 2, Issue 2, 2025 · pp. 29–42 Read article
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Blockchain Enabled IoT System for Tamper Proof Monitoring of Polymer Composite Manufacturing Quality
Abstract: Ensuring real-time process compliance in resin-based polymer composite manufacturing remains a persistent challenge due to non-linear material behaviors, unpredictable curing dynamics, and fragmented sensor data pipelines. Traditional centralized monitoring architectures struggle to guarantee data integrity, auditability, and adaptive response under high-frequency environmental fluctuations. Most existing frameworks fall short in unifying trust, traceability, and time-critical decision-making particularly during critical cure-phase deviations due to limited integration of blockchain with intelligent sensor systems. …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 126–145 Read article
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Technometric Portrait of Sri Vinod Dham, an Indo-US Engineer, Father of Intel Pentium Process: A Quantitative Analysis
Abstract: Vinod Dham is recognized as the ‘Father of Pentium Chip’ or ‘Father of Intel Pentium Process’ in the field of the computer industry, and as an Indo-American pioneer from Silicon Valley. He has contributed 10 research papers during 1982–1986, with an average of two papers per year. This study tries to analyze his contributions through a bibliometric study and draw his familiarity as a world-famous electronic technologist. Data has been …
Published in Research & Reviews : Journal of Statistics · Vol. 14, Issue 3, 2025 · pp. 16–25 Read article
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Biodegradable Polymer Nanocarriers Composites for Biomedical Applications
Abstract: Smart polymeric nanocarriers, or SPNs, have evolved into a fascinating means of delivering medications especially to cancer cells. By improving the efficacy of chemotherapeutic treatments while lowering their negative effects, they have achieved a significant progress in exact medicine. Made to respond to certain elements in the tumours microenvironment, such as enzymes, temperature, pH, and redox conditions, these nanocarriers this reaction to triggers guarantees the release of the medicine at …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 293–305 Read article
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Synthesis, Production, and Mass Balance Analysis of Ten High-Volume Herbicides
Abstract: Herbicides play a crucial role in modern agriculture, enabling effective weed management and safeguarding crop yields amid rising global food demands and growing weed resistance, which can reduce productivity by up to 40%. This study provides a detailed examination of synthesis pathways, production methodologies, and mass balance dynamics for ten high-volume herbicides: Aclonifen, Ametryn, Amidosulfuron, Aminocyclopyrachlor, Aminopyralid, Atrazine, Azimsulfuron, Beflubutamid, Bensulfuron Methyl, and Bentazone, used to control broadleaf weeds, grasses, …
Published in Emerging Trends in Chemical Engineering · Vol. 12, Issue 3, 2025 · pp. 30–44 Read article
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Red Mud Particles' Impact on the Mechanical Properties and Microstructure of AA6005 Composites for Brake Rotor Applications
Abstract: There is increasing focus on utilizing industrial waste as reinforcement in metal matrix composites, driven by the demand for eco-friendly and cost-effective materials in automotive applications. With an emphasis on their possible use in braking rotors, this study examines how red mud particles affect the microstructure and mechanical characteristics of AA6005 aluminum alloy composites. Red mud, a byproduct of the Bayer process, is a good low-cost ceramic reinforcement because it …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 573–581 Read article
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Photoreceptor Dynamics: Light Sensing and Cellular Responses for Photochemistry
Abstract: Photoreceptor dynamics represent a fundamental aspect of photochemistry, encompassing the mechanisms by which biological systems detect and respond to light stimuli. Photoreceptors are specialized proteins that undergo structural and functional changes upon photon absorption, initiating a cascade of molecular events that translate light signals into cellular responses. These proteins are ubiquitous across life forms, including microbial rhodopsins, plant phytochromes, and animal opsins, each finely tuned to specific wavelengths and light …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 3, Issue 2, 2025 · pp. 28–32 Read article
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An Integrative Review of Male Sexual Disorders and the Therapeutic Role of Unani Aphrodisiacs
Abstract: Sexual health is a vital component of overall well-being, encompassing physical, emotional, and psychosocial dimensions. Male sexual dysfunction – including conditions, like erectile dysfunction, premature ejaculation, and low libido – can significantly impact quality of life and intimate relationships. Aphrodisiacs, derived from the Greek goddess Aphrodite, are substances that stimulate sexual desire and performance. Historically, natural aphrodisiacs have been used in various cultures and include plant-based substances such as Yohimbine, …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 3, 2025 · pp. 8–15 Read article
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Cosmeceuticals: Integrating Therapeutic Functionality into Cosmetic Science
Abstract: Cosmeceuticals are a quickly growing group of skincare products that are in between cosmetics and drugs. These products have biologically active components that are said to provide medical or drug-like advantages for a number of skin problems, including ageing, hyperpigmentation, acne, and damage from the sun. Cosmetics are not medications, but cosmeceuticals are made to affect skin function at the cellular level. This article talks about what cosmeceuticals are, how …
Published in Recent Trends in Cosmetics · Vol. 2, Issue 2, 2025 · pp. 19–35 Read article