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1825 articles for “Concentricity”
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Development and Validation of an Analytical Method for Determination of Modafinil in Bulk and Formulations using First Order Derivative UV Spectrophotometer
Abstract: Analytical method validation is an important tool to determine the absolute concentration of drug in the formulation. In the case where a drug is not able to produce characteristic peak shape, a simple, accurate, precise and sensitive method, which will be governed through the software conversion of UV spectra into the first-order derivative, can be used as an alternative method for the estimation of modafinil in bulk and pharmaceutical dosage …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 6, Issue 3, 2019 · pp. 23–29 Read article
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Spectroscopic and Chromatographic Methods for Estimation of Voriconazole in Bulk and Pharmaceutical Dosage Forms
Abstract: Rapid, accurate and precise methods have been developed for estimation of voriconazole in bulk and pharmaceutical dosage forms using Ultraviolet (UV) spectroscopy and reverse phase high performance chromatography (RP-HPLC). The λmax selected in UV spectroscopy method was 255 nm and the calibration curve was linear in the concentration range of 2-50 µg/mL with correlation coefficient (r2)>0.99. In RP-HPLC method, the separation was carried out on Kromasil C18 (250 x 4.6mm, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 8, Issue 1, 2023 · pp. 33–39 Read article
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Simple, Direct and Stability-Indicating UV Spectrophotometric Assay of Pioglitazone Hydrochloride in Pharmaceuticals
Abstract: Pioglitazone hydrochloride (PGH) is an antihyperglycemic agent used in the treatment of type-2 diabetes mellitus. A simple and straight forward UV-spectrophotometric method is presented for the determination of PGH in bulk drug and tablets by measuring the absorbance of drug solution in 0.1M H2SO4 at 269 nm. A plot of absorbance versus concentration obeyed Beer’s law over 2–36 µg ml-1 concentration range (r = 0.9981) with a molar absorptivity of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 8, Issue 3, 2017 · pp. 7–16 Read article
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Microsponges: A Novel Approach for Transdermal Delivery of Tolnaftate
Abstract: The present study was aimed at preparing tolnaftate-loaded microsponges and incorporating them into a topical formulation. Microsponge delivery system was chosen as it can increase the concentration of the drug on the superficial layer of the skin. Microsponges were prepared by quasi-emulsion technique. The studies like drug entrapment efficiency showed that the drug was completely entrapped within the pores of the microsponges. The microsponges were incorporated into the optimized carbopol …
Published in Trends in Drug Delivery · Vol. 2, Issue 2, 2015 · pp. 38–46 Read article
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Formulation and Evaluation of Gastroretentive Bilayered Floating Tablets of Famotidine: Effect of Formulation Variables and in vitro in vivo Evaluation
Abstract: The present investigation concerns the development of bilayered floating tablets of famotidine for prolongation of gastric residence time. An attempt was made to prepare bilayered floating tablets of famotidine by direct compression method. Two layered formulations were designed with an immediate release layer (IR) comprising of the drug, the super disintegrant Croscarmellose sodium along with the other diluents like microcrystalline cellulose and dicalcium phosphate. Three batches of immediate release layer …
Published in Trends in Drug Delivery · Vol. 2, Issue 3, 2015 · pp. 1–17 Read article
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Elemental Impurities: A Review
Abstract: The ICH Q3D is an important guideline to harmonize control of elemental impurities. The guideline sets strict limits for final drug products, limits for excipients, active pharmaceutical ingredients and other pharmaceutical drug products. The analysis of elemental impurities in the pharmaceutical products is most important in pharmaceutical industries. In the last decade noteworthy progress has been made in the analysis of elemental impurities. The changes from using special reagents which …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 1, 2020 · pp. 17–21 Read article
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In vitro and in vivo Anti-Oxidant and Anti-Diabetic Evaluation of cladodes Crude Extract and Solvent fractions of Opuntia elatior mill (Cactaceae)
Abstract: Objective: Ariel part of Opuntia elatior (Cactaceae) has been used in folklare remedies to treat diabetes in America, Mexico and India. However, the anti-diabetic potential of cladodes of this medicinal plant is not scientifically validated and authenticated. The present study aimed to evaluate in vitro and in vivo anti-oxidant and anti-diabetic potential of methanol extracts and solvent fractions of O. elatior cladodes. Methods: Phytochemical analysis performed according to standard procedure. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 2, 2025 · pp. 77–88 Read article
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Metallic Impurities Present in Environmental Water Samples Were Analyzed at Trace Levels Using ICP-MS-KED
Abstract: Elemental impurities in environmental water samples must be carefully monitored since they may have unintended pharmacological and toxicological consequences. For the simultaneous determination of eight metals (Cr, Ni, Cd, Pb, Hg, As, Se, and Sb) in water by ICP-MS, an accurate and sensitive approach has been devised and validated.The method's validity is confirmed through assessment of various criteria for new techniques, including linearity and range, accuracy, precision, selectivity, limit of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 14, Issue 1, 2023 · pp. 53–58 Read article
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Formulation and Evaluation of Buccal Mucoadhesive Bilayered Tablets of Enalapril Maleate
Abstract: The buccal mucoadhesive bilayered tablets of Enalapril Maleate were fabricated with objective of avoiding first pass metabolism and prolonging the duration of action. The tablets were prepared by wet granulation wherein, one layer comprised of drug and bio adhesive polymer, whereas second layer consisted of drug free backing layer of ethyl cellulose. Bioadhesive polymers like Carbopol 934P and one either of three HPMC K4M/ HPMC K15M/ HPMC K100M were employed …
Published in Trends in Drug Delivery · Vol. 1, Issue 1, 2014 · pp. 1–15 Read article
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Anatomization On Controlled Drug Delivery System
Abstract: Modern target-perception technologies have led to the development of successful controlled drug delivery systems. The process of administering a medication so that it is clinically effective in either people or animals is known as drug supply. Several of the earliest controlled-release systems aimed to achieve a delivery profile that would result in a high drug level in the blood for an extended length of time. When using conventional medication delivery …
Published in Trends in Drug Delivery · Vol. 10, Issue 3, 2023 · pp. 24–32 Read article
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Zeolite-Y Encapsulated Copper (II) and Cobalt (II) Species as Hybrid Nano-catalysts: Structural and Catalytic Aspects
Abstract: Special properties inherent to zeolites in facilitating the construction of novel upramolecular assemblies by encapsulation of guest molecules (metal complexes) into their large cages can be utilized to use these assembled materials as novel catalysts. These modified solids have the advantages of both behaving as the homogeneous and the heterogeneous catalytic system. In the present work, copper (II) and cobalt (II) complexes of 2-amino ethanoic acid (2-AEA) encapsulated in the …
Published in Journal of Catalyst & Catalysis Read article
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Model to Predict a Ratio Control of Hydrocarbon Acid and Water in a Packed Bed Reactor
Abstract: Model development was carried out to examine the ratio of hydrochloric acid gas and water in a packed bed reactor. The research predicted increase in output with increase in time, revealing the effectiveness ratio control of hydrochloric acid separation from water using absorption column mechanism. The density of the products played an active role in the separation process as well as in control action function. The developed model can be …
Published in Emerging Trends in Chemical Engineering Read article
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An Optimize Formulation to Synthesis of size Controlled Hydrophobic Starch Acetate Nanoparticles using Box- Behnken Design
Abstract: The best way to improve the overall performance of native starch is by chemical modification. In recent years, hydrophobically modified starch has attracted considerable attention for the design and manufacture of novel nanoparticulate drug delivery carriers. The purpose of this research was to synthesize hydrophobic starch nanoparticles (NPs) and to optimize process factors through the use of response surface methodology (RSM). The corn starch acetate (CSA) NPs was synthesized using …
Published in Journal of Polymer & Composites Read article
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Eco-friendly Azadirachta Indica Ash and Miscanthus Fiber Brick for Carbon Neutrality Environment
Abstract: Naturally grown fiber are not utilized properly they are neglected as wastes. These resources are thrown away due to insufficient research being conducted to discover viable uses for naturally existing fibres. These byproducts have a wide variety of applications in the manufacturing sector, notably in the construction sector. The prospective applications of miscanthus fibre, which may be found growing wild in uncultivated places, are investigated in this research. The production …
Published in Journal of Polymer & Composites Read article
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Evaluation of Tectona Grandis Leaf Extract As A Green Corrosion Inhibitor for Aluminium in 1M NaOH
Abstract: A kind of tropical hardwood tree called the Tectona grandis tree that is indigenous to India. The name "teak tree" is another common name for this kind of tree. It is a member of the plant family that is referred to as Lamiaceae. The primary purpose of this research is to investigate whether or not the plant extract has a corrosion-inhibiting quality. In this study, an aqueous extract of Tectona …
Published in Journal of Polymer & Composites · Vol. 2, Issue 2, 2023 · pp. 41–50 Read article
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Inhibitory Potentials of Datura Metel to Prevent Mild Corrosion
Abstract: The resistance of mild steel to corrosion was evaluated by immersing it in well water and determining the weight it lost after being allowed to return to room temperature after the submersion. The effectiveness of mild steel's ability to withstand corrosion was evaluated using this approach. A reduction in total body mass has an influence that is connected to and helps play a role in the prevention of rusting from …
Published in Journal of Polymer & Composites Read article
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The DVB-H Standard: Comparative Analysis of the Results Obtained for Various Modulation Techniques and Different Code Rates
Abstract: DVB-H happens to be the technical specification for the transmission of digital TV to mobile telephones and PDAs—handheld receivers. Published as a formal standard, DVB-H is a physical layer specification designed to facilitate the proficient delivery of IP-encapsulated data over terrestrial networks. The making of DVB-H, which is closely associated with DVB-T, also entailed modifications of some other DVB standards dealing with data broadcasting, service Information, etc. It can be …
Published in Recent Trends in Electronics Communication Systems Read article
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Treatment of Textile Industrial Wastewater using Hydrophilized Polyamide Nanofiltration Membrane for Water Recovery and Reuse
Abstract: The textile industry is very water intensive. Water is used for cleaning the raw material and for many flushing steps during the entire production process. During the process a large quantity of wastewater is produced which consists of dyes, heavy metals, pigments, and surfactants in high concentration levels all around the world. Dyes and other chemical laden wastewater released by textile industries is a major concern for the treatment which …
Published in Journal of Water Pollution & Purification Research Read article
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Assessment of Groundwater Quality in Rumuodara, Rivers State, Nigeria
Abstract: The assessment of groundwater quality from selected borehole in Rumuodara, Rivers State, Nigeria was evaluated. The results of the physicochemical parameters revealed that pH ranged from 6.57-6.60, temperature: 26.10-28.54oC, turbidity: 1.57-2.96NTU, conductivity: 41.24-68.44 μS/cm, salinity: 26.10-50.37mg/l, total dissolved solid: 18.9-63.14mg/l, total hardness: 38.21-48.30mg/l, alkalinity: 55.30-70.17mg/l, chloride: 28.40-75.14mg/l, sulphate: 21.50-30.60mg/l, nitrate: 1.50-3.04mg/l, phosphate: 59.24-65.40mg/l, calcium: 37.81-45.27mg/l, Iron: 0.133-0.190mg/l, sodium: 16.70- 21.13mg/l, copper: 0.22–0.50mg/l, total suspended solid: 2.94-3.60mg/l, Lead: < 0.01mg/l-2.27mg/l, zinc: …
Published in Research & Reviews : Journal of Ecology Read article
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Productions and Characterization of Biodiesel by Base Catalyzed Transesterification Reaction from Dairy Waste Scum of DEI Dairy, Agra
Abstract: With the increase in prices and rapid depletion of petroleum-based fuels, the investigation is being done to look over an alternative fuel source. Presently, the biodiesel is mainly produced from vegetable sources such as jatropa oil, karanja oil, rapeseed, soybean, and others that could overlap with nutritional requirement of the society if produced at large scale. Also, the production cost of biodiesel from vegetable and animal sources is very high …
Published in Research and Reviews : Journal of Dairy Science and Technology Read article