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940 articles for “patients”
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A Narrative Review on Osteogenesis Imperfecta and Its Management
Abstract: Osteogenesis imperfecta (OI), sometimes referred to as brittle bone disease, is a heterogeneous illness characterized by short stature, several fractures, and distorted bones. The main contributing factor to OI is mutations in the genes needed to produce type 1 collagen. While severe OI is perinatally fatal, mild OI can occasionally not be detected until maturity. The frequency of Osteogenesis imperfecta ranges from about 1:15,000 to 1:20,000 births. Five kinds of …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 1–10 Read article
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A Study to Assess the Effectiveness of Body Mechanics Training Programme on Reducing Low Back Pain Among Nursing Officers Working in Selected Hospitals, Bangalore
Abstract: Background: Low Back Pain (LBP) is a common work related injury and costly problem among the nursing profession. Numerous studies indicate a greater occurrence of back pain and work-related back injuries among nursing officers in comparison to other occupations. Prevention of LBP is a very important technique to maintain proper body mechanics. This study aimed to assess the effectiveness of body mechanics training programme on reducing low back pain among …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 29–62 Read article
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Chemical Preparation Methods of Nano Material with their Applications
Abstract: Scientists were not satisfied with the diagnosis, exploration, injection and imaging through modern medical nanotechnology, but they were also able through this technology to activate smart microscopic bombs that target the cancer cell and detonate it, killing the cancer cells. This technology was tested on laboratory mice and achieved great success. Nanotechnology is the technology of the future, not only in the medical and therapeutic aspect, but also in everything …
Published in Journal of Petroleum Engineering & Technology · Vol. 14, Issue 2, 2024 · pp. 1–9 Read article
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Chemical Preparation Methods of Nano Material with their Applications
Abstract: Scientists were not satisfied with the diagnosis, exploration, injection and imaging through modern medical nanotechnology, but they were also able through this technology to activate smart microscopic bombs that target the cancer cell and detonate it, killing the cancer cells. This technology was tested on laboratory mice and achieved great success. Nanotechnology is the technology of the future, not only in the medical and therapeutic aspect, but also in everything …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 2, 2024 · pp. 1–9 Read article
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Unlocking Potential: Capecitabine’s Evolution as an Anticancer Wonder Drug
Abstract: Capecitabine, a precursor to 5-fluorouracil (5-FU), is Anticancer Drug in treating solid tumors like colorectal, breast, and gastric cancers. Its mechanism involves converting to 5-FU mainly within tumor cells, reducing toxicity while maximizing effectiveness. Besides being effective alone, it is also valuable in combination therapies, showcasing its versatility in cancer treatment. This review explores the transformative journey of capecitabine as a pivotal anticancer drug. Beginning with an introduction to its …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 17–24 Read article
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Implementing Quality by Design (QbD): Strategies, Challenges, and Best Practices across Industries
Abstract: The present comprehensive review investigated the dynamic landscape of quality standards within the pharmaceutical sector, with a primary focus on the implementation and impact of Quality by Design principles. It illuminated the multifaceted challenges encountered by pharmaceutical companies in upholding stringent quality standards amidst evolving regulatory requirements and complex manufacturing processes. By embracing Quality by Design principles, the industry aims to foster a proactive and systematic approach to product development …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 28–36 Read article
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Report Pulse: Using Machine Learning
Abstract: This study presents the development of a novel medical report analyzer, specifically designed to streamline the interpretation of complex health data. The Report Pulse project represents a significant advancement in healthcare innovation, aiming to facilitate deeper insights into medical reports and foster personalized health management strategies. At its core, the Report Pulse project introduces a sophisticated blood report analyzer, which transcends conventional data analysis by providing actionable insights tailored to …
Published in Journal of Computer Technology & Applications · Vol. 15, Issue 2, 2024 · pp. 28–33 Read article
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Blockchain, Evolution, and Future Scope: An Overview
Abstract: A blockchain serves as a transparent and immutable record of transactions, offering unparalleled security and trust in a digital environment. Its decentralized nature ensures that no single authority has control over the network, fostering a level playing field for all participants. While cryptocurrencies such as Bitcoin have popularized blockchain technology, its potential extends far beyond digital currencies. In addition to financial transactions, blockchain can revolutionize various industries, including supply chain …
Published in Journal of Advanced Database Management & Systems · Vol. 11, Issue 2, 2024 · pp. 14–24 Read article
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Current Drugs Target the EGFR
Abstract: Cancer is a devastating disease, but there have recently been significant advancements in therapy that have identified EGFR and its related proteins as valuable indicators and targets for treatment. The ERBB receptor tyrosine kinase superfamily includes EGFR, which is a transmembrane glycoprotein. When the EGFR receptor interacts to its particular ligand, EGF, it causes tyrosine residues to be phosphorylated and forms receptor dimers with other members of the receptor family. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 1–8 Read article
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An in-silico toxicity study of the phytocompounds found in Pongamia pinnata leaves using the ProTox-II web server
Abstract: The aim of the current study was to determine the Insilco toxicity of the phytocompound present in the leaves of Pongamia pinnata. The leaves of Pongamia pinnata have long been used in traditional medicine for their therapeutic properties. Nowadays, herbal toxicity is a common problem caused by incorrect dosage. The FDA reviews the safety and effectiveness of herbal products only in response to patient or health care provider complaints—problems with …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 13, Issue 1, 2024 Read article
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Computer-aided Drug Design Method for Anti-hepatitis C Drug Design
Abstract: Hepatitis C is a disease caused by the hepatitis C virus and can cause serious liver damage. There is currently no vaccine for this disease and the number of infections continues to increase worldwide. Currently used antiviral drugs are interferon alfa-2a and ribavirin, but about half of patients do not respond to therapy. Therefore, new drugs that protect against hepatitis C need to be investigated. Computational drug methods have been …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 1–8 Read article
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A Secure and Transparent Voting System Leveraging Ubiquitous Computing and Blockchain Technology
Abstract: Ubiquitous computing and blockchain technology are two pivotal innovations driving significant changes in the digital world. This article explores the intersection of these technologies, analyzing how their combination can unlock new opportunities and address existing challenges. Ubiquitous computing envisions seamlessly integrating computing capabilities into everyday objects and environments, aiming to enhance user experience and efficiency. Meanwhile, blockchain technology, known for its decentralized and secure nature, offers robust solutions for transparency, …
Published in Journal of Advancements in Robotics · Vol. 11, Issue 2, 2024 · pp. 9–13 Read article
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Editorial: Advancements in Movement Analysis for Understanding Neurological Disorders
Abstract: Neurological disorders pose a significant challenge, demanding innovative approaches for accurate diagnosis, effective treatment, and deeper understanding. Movement analysis emerges as a powerful tool, offering a quantitative window into the complexities of motor function. This editorial delves into the transformative impact of movement analysis on neurological research and clinical practice. Traditional diagnostic methods, reliant on subjective observations, often miss subtle motor impairments, particularly in early disease stages. Movement analysis tackles …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 28–32 Read article
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Panfacial Trauma- A Case Report
Abstract: The majority of panfacial fractures are accompanied by concurrent organ damage. Panfacial fracture management is difficult and necessitates careful planning, sequencing, and sufficient understanding of the anatomy and management of the condition. In any trauma situation, the ABCDEs (airway, breathing, circulation, disability, and exposure) always remain the primary care priorities. Maxillofacial surgeons are essential in the early stabilization of fractures, the management of localized bleeding into the face, and the …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 2, 2024 · pp. 21–25 Read article
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Practical approach for Type 2 Diabetes: Role of DPP4 Inhibitors
Abstract: Dipeptidyl peptidase-4 inhibitors (DPP-4Is) have become essential in managing type 2 diabetes mellitus (T2DM) due to their ability to enhance incretin hormone activity, which promotes insulin secretion and inhibits glucagon release. These agents effectively lower HbA1c levels by 0.5–1.0%, are weight-neutral, and have a low risk of hypoglycemia, making them suitable for a broad patient population, including the elderly. The antidiabetic market in India is vast. Gliptin as group row …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 20–26 Read article
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Comprehensive Analysis of MRSA Peptides Via Maldi
Abstract: The present study employed Matrix-Assisted Laser Desorption/Ionization Time-of-Flight mass spectrometry to analyze methicillin-resistant Staphylococcus aureus peptides, focusing on various parameters associated with mass-to-charge (m/z) values. Through systematic data collection and analysis, including time, intensity, signal-to-noise ratios, quality factors, resolutions, areas under the peaks, relative intensities, full widths at half maximum, Chi-squared values, and background peaks, comprehensive insights into the spectral characteristics of methicillin-resistant Staphylococcus aureus peptides were obtained. Methicillin-resistant Staphylococcus …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 98–101 Read article
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An Effective & Novel Approach as Gastro-retentive Drug Delivery Systems
Abstract: Researcher’s curiosity about gastro-retentive drug delivery system increased so high in recent years because of its excellent drug releasing properties to the target site. The delivery system's residence time in the stomach can be extended with the usage of gastro-retentive drug delivery system by using a number of natural and synthetic polymers such as guar gum, hydoxy propyl methyl cellulose which can be used to improve the bioavailability of a …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 47–54 Read article
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Exploring Biomedical Innovations in the Formulation and Assessment of Medicated Hard Candy Lozenges Containing Metoclopramide Hydrochloride
Abstract: The objective of this study was to formulate and evaluate metoclopramide hydrochloride medicated lozenges for antiemetic action through buccal absorption by incorporating a polymer. All formulations were developed and assessed for in-vitro drug release, physical appearance, weight variation, thickness, hardness, moisture content, mouth-dissolving time, and drug content. The prepared lozenges exhibited uniformity in weight and thickness. The hardness of all formulations ranged between 7.3–15.50 kg/cm², falling within standard limits. The …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 50–62 Read article
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A Study to Identify the Risk Factors and Level of Knowledge Regarding Stroke Among Adults in Selected OPD at Tertiary Care Hospital, Puducherry
Abstract: The aim of the study was to identify the risk factors and level of knowledge regarding stroke among adults in selected OPD at Tertiary Care Hospital, Puducherry. In this study descriptive design was used, consecutive sampling technique was used to select the samples for this study. Data was collected through Structured Questionnaire was used to assess the level of knowledge and checklist was used to identify the risk factors of …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 2, 2024 · pp. 32–38 Read article
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A Novel Categorization System for Pressure Ulcers Reframed in the Context of Bioinformatics
Abstract: Pressure sores are a serious complication of multi morbidity and lack of mobility. Pressure injuries are commonly encountered in geriatric patients. Certain well-recognized risk factors, such as immobility and incontinence, may predispose to the development of pressure injury (PI); consequently, risk factor modification is an important aspect of prevention and treatment. One of the fundamental documentation details when describing a wound is the use of the appropriate staging system. Each …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 2, 2024 · pp. 1–5 Read article