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1680 articles for “BCS Class II/IV drugs”
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Emerging Digital Trends in Virology Software: Optimizing Viral Discovery, Surveillance,and Patient Management.
Abstract: Virology and antiviral therapeutics are being reshaped by rapid advances in computational tools, automation platforms, and virus-focused digital health applications. Software systems now span the entire virology value chain, from in silico viral target identification and antigen design, to AI-supported clinical trial management for vaccines and antivirals, to post-marketing pharmacovigilance and patient-facing mobile tools. This review examines current and emerging software trends relevant to virus studies, emphasizing applications in viral …
Published in International Journal of Virus Studies · Vol. 3, Issue 1, 2026 · pp. 29–38 Read article
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REVIEW OF PHARMACOEPIGENETICS: BRIDGING EPIGENETICS AND PERSONALIZED MEDICINE
Abstract: Pharmacoepigenetics is an emerging field that explores how alterations in gene expression, independent of DNA sequence changes, influence individual responses to drugs. Unlike pharmacogenetics, which focuses primarily on genetic variation, pharmacoepigenetics integrates genetic, environmental, and lifestyle factors to explain interindividual differences in drug efficacy, toxicity, and resistance. Key epigenetic mechanisms including DNA methylation, histone modifications, non-coding RNAs, and RNA methylation play critical roles in regulating drug metabolism and therapeutic outcomes. …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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AI-Powered Emotion Recognition in Dog
Abstract: Understanding animal emotions is important for improving veterinary care, human animal interaction, and overall pet well-being. Inspired by previous research that utilized a modified EfficientNetB5 model for emotion classification in cats and dogs, our study builds upon this foundation with a focus on real-time emotion recognition in dogs. While earlier approaches achieved high accuracy using Dense Residual and Squeeze-and-Excitation blocks, they often lacked real-time applicability and were not optimized for …
Published in International Journal of Machine Systems and Manufacturing Technology · Vol. 4, Issue 1, 2026 · pp. 20–32 Read article
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GLP-1 Receptor Agonists: A Dual Therapeutic Strategy for the Management of Type 2 Diabetes Mellitus and Obesity
Abstract: For the treatment of obesity and type 2 diabetes mellitus (T2DM), glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have become a revolutionary class of pharmaceutical drugs. These drugs were first created as glucose-lowering treatments, but they have now shown other advantages, such as notable weight loss, better cardiovascular results, and general metabolic control. The objective of this narrative review is to assess the pharmacological mechanisms, clinical efficacy, safety profile, and therapeutic …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 69–75 Read article
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How do Polymer-derived Implants Influence Patient-Reported Outcomes (PRO) in Cardiovascular and Orthopaedic Procedures
Abstract: Implants derived from polymers have surfaced as adaptable substitutes for conventional metallic devices in cardiovascular and orthopedic treatments because of their adjustable mechanical characteristics, biocompatibility, radiolucency, and ability for surface alteration. This systematic review assesses the impact of polymer-based implants such as PEEK, UHMWPE, bioresorbable polymer scaffolds, and drug-eluting systems on outcomes reported by patients (PROs). Findings from 42 qualifying studies show overall positive impacts on pain alleviation, functional recovery, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1821–1834 Read article
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Plant-Derived Antimicrobials as Next-Generation Solutions to Multidrug Resistance
Abstract: The steady rise of multidrug-resistant (MDR) pathogens is reshaping how clinicians, researchers, and policymakers think about infection control. When bacteria acquire the ability to survive exposure to three or more antibiotic classes at once—whether through efflux pumps, enzyme-mediated drug destruction, target modifications, or reduced membrane permeability—treatment options narrow dramatically, hospital stays lengthen, and mortality climbs. Conventional pharmaceutical pipelines have struggled to keep pace with this biological arms race, pushing the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 Read article
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Application of Natural and Synthetic Polymer-Based Disintegrants in the Design of Fast Dissolving Cefuroxime Axetil Tablet Composites
Abstract: The current paper examines how natural and synthetic polymer-based disintegrants can be used to design fast-soluble types of tablet composites. A model drug was chosen and tablets were prepared by the direct compression method using different polymeric excipients, such as guar gum, locust bean gum, sodium starch glycolate (SSG) and cross povidone. Eight formulations were prepared and tested on the basis of critical material and performance characteristics including thickness, hardness, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1348–1360 Read article
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Hydrolysis-Driven Optimization of Hydroxypropyl Maize Starch for Improved Micro-Pellet Binding and Quick Solubility of Spirulina-Based Micro-Pellets
Abstract: Acid hydrolysis is a well-established approach for modifying the physicochemical properties of polysaccharides & macromolecules including hydroxypropyl Maize starch (HPMS). In this study, the effect of varying concentrations of hydrochloric acid on the partial hydrolytic degradation of HPMS (Lycoat RS-780) was investigated at 85°C for 4 h, yielding polymers of different molecular weights. The Acid-mediated degradation effects on polymer characteristics were systematically assessed using capillary viscometry and gel permeation chromatography …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 3, 2026 Read article
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Modern Approaches in Lung Cancer Management from Herbal Nanomedicine to Artificial Intelligence
Abstract: Lung cancer continues to be a major global health concern and one of the leading causes of cancer-related mortality worldwide. Despite significant advancements in therapy, there is still a pressing need for safer and more effective therapeutic alternatives; problems such drug resistance, side effects, metastasis, and recurrence continue to impact patient outcomes and quality of life. Examining current advancements in the use of herbal drug-loaded nanoparticles as a novel approach …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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Evaluation of Anti-cataract Potential of Carbocisteine by Using In Vitro Goat Lens Model
Abstract: This study includes Carbocisteine has four Oxygen molecules, one Sulfur molecule, and one Nitrogen molecule. Goat eyeballs were used in the present study. They were obtained from the slaughterhouse. Glucose at a concentration of 55 mM was used to induce cataracts; glucose (5.5 mM) concentration served as a normal control, and Ascorbic Acid served as a standard control. Incubation of lenses with glucose 55 mM showed opacification starting after 8 …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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Silicon Symphony: The Science of Semiconductors Circuits
Abstract: Modern electronics are built on the foundation of semiconductor circuits, which precisely and efficiently control the flow of electrical impulses. This article takes a look at the underlying physics of semiconductor materials and how their unique electrical properties allow the design and functioning of diodes, transistors and integrated circuits. This study links microscopic scientific principles to the behaviour of real circuits. It considers essential concepts such as charge carriers, doping …
Published in International Journal of Solid State Innovations & Research · Vol. 4, Issue 1, 2026 Read article
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Medicinal Properties of Oxytenanthera abyssinica: A Narrative Review
Abstract: Oxytenanthera abyssinica, a plant local to the African landmass, has gotten a parcel of intrigued in later a long time for its conceivable restorative benefits; it has been utilized in conventional medication for decades since of its assumed mending capabilities. In spite of its long history, careful logical examination into its restorative potential is being attempted. This review paper explore into the multidimensional part of O. Abyssinica is in progressed …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 2, 2026 Read article
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Artificial Intelligence and Edge Computing in Oil and Gas: Applications, Architectures, and Operational Realities
Abstract: Artificial intelligence has arrived in oil and gas, and unlike some previous waves of digital enthusiasm in the sector, this one is sticking. Saudi Aramco analyses approximately 10 billion data point every day and reported USD 4 billion in technology-driven operational gains in 2024. ExxonMobil uses AI to increase shale well output by more than 5 percent. Shell has deployed machine learning across more than 10,000 assets using C3.ai to …
Published in Journal of Petroleum Engineering & Technology · Vol. 16, Issue 2, 2026 · pp. 01–06 Read article
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Properties of Biodegradable Films based on Pectin, Mango Kernel Flour and Unrefined Palm Oil
Abstract: This study allowed to develop biodegradable films based on pectin, incorporating mango kernel flour and unrefined palm oil, whose physical and mechanical properties were investigated. Results highlighted the feasibility of developing of these composite films. The film properties showed variability in color, physical, barrier and mechanical properties, depending to concentration of ingredients. Biodegradable films obtained are homogeneous, non-cracked, uniform, and color is mainly orange. Opacity of films increased with the …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 52–62 Read article
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A Comprehensive Investigation of Bagging-Based Ensemble Methods for Improving Machine Learning Model Robustness
Abstract: Machine learning models such as Decision Trees, Logistic Regression, and K-Nearest Neighbors are widely used for classification tasks due to their simplicity and interpretability. However, these models often suffer from high variance, overfitting, and poor generalization when applied to real-world datasets, particularly those that are small, noisy, or imbalanced, as commonly encountered in healthcare, finance, and cybersecurity applications. To address these limitations, this research proposes a Bagging (Bootstrap Aggregating)-based ensemble …
Published in Recent Trends in Mathematics · Vol. 3, Issue 2, 2026 · pp. 24–34 Read article
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Brief Concept of Waja ul Mafasil and its Management in Unani System of Medicine: A Review
Abstract: Waja-ul-Mafasil (Osteoarthritis) also known as degenerative arthritis is a progressive joint disease, occurring in middle and later life. Osteoarthritis is a leading cause of disability worldwide despite its development in prevention, diagnosis, and treatment. A comprehensive description of Waja-ul-Mafasil is available in classical Unani literature. While going through the literature review of various compendiums written by Unani scholars, it is clear that this system of medicine had huge knowledge about …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy Read article
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Image Preprocessing and Analysis on Eye Fundus Images Segmentation by Using Density Clustering Methods
Abstract: In order to do an automated evaluation of various retinal illnesses such as Diabetic retinopathy, Glaucoma, and Macular Edema, fundus images must be pre-processed first. For many reasons, it's difficult to accurately detect the optic disc. Many blood vessels cross the optic disc, making it difficult to discern the disc's boundaries in fundus images. Lesion regions in diabetic retinopathy look very much like an optic disc's colour and texture, so …
Published in Recent Trends in Sensor Research & Technology Read article
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A Review: Carissa Carendas Leaves: Phytochemical Constituents, Traditional Use, and Pharmacological Properties
Abstract: Carissa carendas called Karanda are used in many traditional systems Unani, Ayurveda, homeopathic systems. Traditionally various herbal drugs used in curing many diseases are used singly or in a combination of another herbal drugs. Carissa carendas is all part of plant-like fruit, root, leaves all parts is used to treat many diseases traditionally. Various herbal drugs individually or in combination have been recommended for the treatment of different diseases. The …
Published in Research & Reviews : Journal of Botany Read article
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Antibiotic Resistance: Molecular Mechanisms of Resistance
Abstract: Antibiotics are called as ‘Wonder Drugs’, the miracles of modern sciences. They help combat bacteria and prevent their growth. But due to unmonitored and uncontrolled consumption of these antibiotics, there is an emergence of antibiotic resistance. This has led to a series of downfall in the therapeutic potency and efficacy of many drugs. More and more bacteria are becoming Multi-Drug Resistant (MDR); such highly resistant strains of certain bacteria are …
Published in Research and Reviews: A Journal of Microbiology and Virology Read article
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Live Integrated Facial Observation (L.I.F.O.)
Abstract: A human face is the most influential part of humans that can uniquely identify a person. Using all the facial characteristics as biometric, the LIFO system can be applicable in many different ways. Like in everyday life, the most mandatory task in any organization is attendance marking. Earlier, people used to mark their presence using paperwork but now along with the advancement of technology, this system has also changed and …
Published in Journal of Advancements in Robotics Read article