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1972 articles for “(DES)” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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An Extensive Analysis of Computer-Aided Drug Design for Novel Psychotropic and Neurological Substances
Abstract: A comprehensive review of the use of computer-aided drug design (CADD) in the creation of innovative neurologic and neuropsychiatric medications is given in this article. It discusses the challenges in traditional drug discovery approaches and highlights the role of computational methods in accelerating the identification and optimization of drug candidates targeting psychiatric and neurological disorders. The method of finding new drugs has been completely transformed by Computer-Aided Drug Design (CADD), …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 19–27 Read article
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A Review on Anesthetic Drug Discovery with Computer Aided Drug Design
Abstract: In contemporary medicine, anaesthesia is essential for enabling surgical procedures, pain control, and patient comfort. Finding and creating safe and efficient anaesthetics is crucial to enhancing patient outcomes and developing the medical field. In this review, we provide a comprehensive overview of anesthetic drug discovery with a focus on the integration of computer-aided drug design (CADD) methodologies. Beginning with an exploration of anesthesia mechanisms and targets, we delve into the …
Published in International Journal of Antibiotics Read article
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Integration of Vertical Axis Wind Turbines into Urban Environments: Feasibility and Design Considerations
Abstract: Abstract This study aims to comprehensively investigate the performance of Savonius rotor wind turbines through a combination of numerical simulations and experimental testing. Initially, 3-dimensional CAD software Solidworks and ANSYS will be utilized to design detailed models of the turbines. Numerical meshes will then be generated around these models using FLUENT software, incorporating the k-ε turbulence model to simulate fluid flow fields. Parameters such as drag coefficient, lift coefficient, pressure …
Published in Journal of Aerospace Engineering & Technology · Vol. 14, Issue 2, 2024 · pp. 20–25 Read article
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From Concept to Road: A Review of Chassis Design for Electric Vehicles
Abstract: The automotive industry is undergoing a rapid transformation propelled by the electric vehicle (EV) revolution, with the chassis serving as a pivotal element. In this paper chassis designs the unique characteristics of electric vehicles. The traditional internal combustion engine (ICE) chassis is being redefined to optimize performance, safety, and efficiency for electric propulsion systems. The absence of a traditional engine and the integration of electric motors pose new challenges and …
Published in Trends in Electrical Engineering · Vol. 14, Issue 2, 2024 · pp. 20–27 Read article
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Child Care Centers: Designing Spaces for Wellness and Development of Children
Abstract: Hospital design has changed and evolved since the Modern Movement in architecture to meet the demands of the times. It is now believed to be dependent on several variables. An architect should design a space that promotes security and is advantageous to the patient. An inpatient's hospitalisation procedure is unavoidably stressful for them. For adults, the atmosphere of healthcare facilities matters a lot, but for paediatric patients, it matters much …
Published in International Journal of Children · Vol. 1, Issue 2, 2024 · pp. 15–23 Read article
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Exploring the State-of-the-art in Plug-in Hybrid Electric Vehicle Design and Modeling: A Review
Abstract: This document provides a thorough explanation of the process involved in designing and developing plug-in hybrid electric vehicles (PHEVs). A viable way to lessen greenhouse gas emissions and reliance on conventional internal combustion engine vehicles is through plug-in hybrid electric vehicles (PHEVs), which have gained popularity in response to growing concerns about environmental sustainability and the depletion of fossil fuels. The main elements, design factors, difficulties, and developments in the …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 1, Issue 2, 2023 · pp. 8–15 Read article
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Optimized Web-based Online Food Ordering System: Design and Implementation
Abstract: Online food ordering systems have undergone a profound metamorphosis with the advent of digital technologies, catalyzing a pivotal shift in the operational dynamics of the gastronomic sector. This paper elucidates the conceptualization, design, and implementation of an advanced, web-based food ordering system, meticulously engineered to elevate the efficiency and sophistication of food service operations. Employing the rigorously structured Systems Analysis and Design Methodology (SSADM), this system represents a transformative departure …
Published in International Journal of Computer Science Languages · Vol. 2, Issue 2, 2024 · pp. 1–25 Read article
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Performance Optimization of Photovoltaic-thermal (PVT) Systems: A Comprehensive Review of Design and Efficiency Enhancements
Abstract: The desire for renewable energy solutions and the rising demand for energy worldwide have driven important developments in hybrid photovoltaic-thermal systems. Photovoltaic-thermal systems provide the advantages of both thermal energy collection and electrical energy generation as they integrate photovoltaic and thermal collectors into a single module. However, a number of variables, including system architecture, material choice, cooling systems, and ambient circumstances, affect how well they function. The goal of this …
Published in Journal of Refrigeration, Air conditioning, Heating and ventilation · Vol. 11, Issue 2, 2024 · pp. 9–16 Read article
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Design of a Water-Cooling System for the Inside Roof of 20t Electric Arc Furnace for Oxygen Blow Decarburization Using CFD Analysis
Abstract: An electric arc furnace (EAF) roof usually works at high temperature for a long time, undergoes not only heat radiations from electric arc, molten metal, and lining of high temperature, but also is washed and affected by chemical erosion due to high temperature and gas flow. In addition, it might be eroded by slag with high temperature. In， inside roof of EAF is more severely affected by heat load than …
Published in Journal of Thermal Engineering and Applications · Vol. 11, Issue 3, 2024 · pp. 11–17 Read article
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Review on Computer-Aided Drug Design in RAS Inhibitor Discovery
Abstract: This review explores the utilization of computer-aided drug design (CADD) methodologies in the discovery of inhibitors targeting the RAS pathway, a pivotal signaling cascade implicated in various cancers. Through an extensive examination of computational tools, methodologies, challenges, and recent advancements, this review aims to provide insights into the role of CADD in accelerating RAS inhibitor discovery. The discovery of effective inhibitors targeting the RAS pathway is of paramount importance in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 7–14 Read article
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Design and Validation of Polymer-Separated Lithium-Ion Battery Powered Mini-UPS for Networking Applications
Abstract: Due to the growing use of semiconductor-based electronic devices in networking applications, power interruptions can cause data loss, productivity loss, and system disruptions. To eliminate these outages, Mini Uninterruptible Power Supplies are expensive and have single-use batteries with shorter battery lives. These networking wires, cables, and other electrical components are polymer-insulated. Polymers with low dielectric constants have the potential to improve antenna interlayer dielectrics, communication cables, and other hardware for …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 917–933 Read article
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Enhancing Ship Roll Stabilization: Design of Active Fin Stabilizers Using Auto-Tuned PID Controllers
Abstract: The rolling motion of any type of mechanical system can be realized by the linear differential equation with some constant coefficient. In the domain of marine industries, it is observed that the stabilization of the ship’s roll motion is required due to the occurrence of the most unwanted water wave disturbances at the sea. It may cause serious types of damage to the equipment related to the ship. Active fin …
Published in Journal of Experimental & Applied Mechanics · Vol. 15, Issue 3, 2024 · pp. 18–31 Read article
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The Effect of Packaging Design Elements on Purchase Intention of Junk Food Among College Students
Abstract: This research investigates the impact of packaging design elements on the purchase intention of junk food among college students. Recognizing the influence of visual appeal on consumer behavior, particularly within young adult demographics, this study aims to identify which specific packaging elements, such as color, imagery, typography, and branding, resonate most with college students when choosing junk food. A descriptive survey method was used, targeting students in Delhi NCR, with …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 14, Issue 3, 2024 · pp. 39–47 Read article
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Piezoelectric Energy Harvesting Using A 10x10 Sensor Matrix with Integrated Circuit Design for Pressure Control
Abstract: This project aims to create a system that generates energy using piezoelectric technology, designed as a rectangular tile platform. The platform has two layers of sensors arranged in a 10 × 10 grid, connected in a mix of series and parallel setups. The top layer acts as a surface for external forces, like footsteps, while springs connect the layers to control pressure and maximize energy generation. A rectifier ensures the …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 2, Issue 2, 2024 · pp. 47–53 Read article
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Vibrational Wind Turbine Design
Abstract: This work focuses on the study and analysis of bladeless wind turbines (BWT) as an alternative to operating vertical-axis wind turbines (VAWT) and horizontal-axis wind turbines (HAWT). A mathematical analysis of the BWT oscillation under wind force allows the development of specific mathematical expressions for the oscillation speed and BWT mast displacement at any height. The oscillation movement is submitted to a Strouhal constant number condition, resulting in an algorithm …
Published in Journal of Offshore Structure and Technology · Vol. 11, Issue 3, 2024 · pp. 32–45 Read article
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Drug Design and Process Chemistry: Bridging the Gap between Discovery and Manufacturing
Abstract: This review explores how drug discovery connects with process chemistry to enable large- scale pharmaceutical manufacturing. While drug discovery identifies and optimizes therapeutic compounds, process chemistry adapts these compounds for mass production, addressing challenges in scalability, cost, and quality. The article examines the role of early collaboration between drug designers and process chemists, recent innovations in green chemistry and flow chemistry, and case studies that illustrate successful scale-up strategies. Emerging …
Published in Trends in Drug Delivery · Vol. 12, Issue 1, 2025 · pp. 09–21 Read article
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Advanced 4-Element UWB-MIMO Antenna Design: Achieving High Isolation and Multi-Band Rejection for Advanced Wireless Applications
Abstract: In this study, we present the design, fabrication, and analysis of a step-by-step Ultra-Wideband (UWB) Multi-Input Multi-Output (MIMO) antenna operating from 3 to 14 GHz. The antenna consists of four elements, each characterized by high isolation and equipped with four band-rejection features. These elements are implemented on a Rogers substrate with εr=3. Each antenna element is a modified rectangular patch, incorporating partial ground etching to achieve wider bandwidth. Two sets …
Published in Journal of Communication Engineering & Systems · Vol. 15, Issue 1, 2025 · pp. 40–62 Read article
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Integrating Green Infrastructure in Urban Development and Street Design: A Comprehensive Approach to Sustainable Urbanization and Environmental Planning
Abstract: This study examines the comprehensive integration of green infrastructure in both urban development and street design as a critical approach to achieving sustainable urbanization and effective environmental planning. It explores the role of green spaces, permeable pavements, tree-lined streets, and natural water management systems in addressing urban challenges such as heat islands, flooding, and air pollution. Case studies from cities worldwide are reviewed to demonstrate the environmental, social, and economic …
Published in International Journal of Urban Design and Development · Vol. 3, Issue 1, 2025 · pp. 8–15 Read article
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A Low Embodied Energy Approach for Early Design Decisions in Agritourism Centers in Pune
Abstract: Agritourism is an idea that empowers and trains the rural family, organization, or individual to generate alternative sources of income by transforming their traditional agricultural land into a tourist attraction. Agritourism is the practice of attracting visitors to an area used primarily for agricultural purposes. It could be described as – rural/agricultural environments + farm commodities + tourism services = agritourism. It gives visitors an experience to stay in a …
Published in International Journal of Rural and Regional Development · Vol. 3, Issue 1, 2025 · pp. 29–41 Read article
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Beyond Taste: The Impact of Sensory Design on Dining Interiors
Abstract: Dining experiences are increasingly recognized as multisensory events where the atmosphere of the environment significantly influences the overall perception of the meal. This study explores the impact of sensory design, encompassing visual, auditory, olfactory, tactile, and gustatory elements, on dining interiors. By examining the roles of color, lighting, acoustics, textures, and spatial arrangements, this study investigates how these factors contribute to customer satisfaction, behavior, and memory formation. Through an analysis …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 3, Issue 1, 2025 · pp. 8–15 Read article