Search
701 articles for “3-(4”
-
In Silico Pharmacological Evaluation of Certain Commercially Available Terpenoids As Αlpha-Amylase Inhibitors for The Management of Diabetes Mellitus.
Abstract: The objective of this study was to investigate the α-amylase inhibitory activity of certain commercially available terpenoids using in silico docking studies. In this perspective, terpenoids like Abietane, Artemisinin, Carvone, Cucurbitane, Ferruginol, Lupeol, Nerolidol, Retinol, Sabinene, and Zingiberene were selected. Glibenclamide, a well-known antidiabetic drug was used as the standard. In silico docking studies were carried out using AutoDock 4.2, based on the Lamarckian genetic algorithm as the working principle. …
Published in Research and Reviews : Journal of Computational Biology Read article
-
A Case Study on Ayurvedic Management of Psoriasis.
Abstract: Psoriasis is non-contagious, chronic autoimmune disease which causes inflammation and hyper-proliferation of the skin. It is characterized by erythematous plaques that are clearly defined and associated with severe itching and silvery scaling, especially on extensor surfaces, scalp and nails. At times, it may manifest as localized or generalised pustular eruption which usually follows relapses and remissions pattern. Psoriasis may lead to other autoimmune diseases like psoriatic arthritis. In Ayurveda, Variety …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2024 · pp. 18–22 Read article
-
Study and Thermal Analysis of a Rectangular Duct with Z-shaped Baffle Using Ansys
Abstract: This project aims to enhance heat transfer in a rectangular duct by utilizing Z-shaped baffles. It involves creating a 3D CAD model using SolidWorks and validating it in ANSYS Fluent 2019 R2. The study focuses on analyzing the effect of baffle arrangement, height, and angle on heat transfer rate. Comparative analysis is conducted between rectangular ducts with a 60° angle and heights of 4 mm, 6 mm, and 8 mm. …
Published in International Journal of Energy and Thermal Applications · Vol. 1, Issue 2, 2023 · pp. 14–30 Read article
-
Prevalence and Risk Factors of Neglected Tropical Diseases Among Women and Children in Rural Liberia: A Regional Perspective
Abstract: Neglected Tropical Diseases (NTDs) remain a critical public health challenge in Liberia, disproportionately affecting women and children in rural regions due to systemic inequities in water, sanitation, and healthcare access. This cross-sectional study assessed the prevalence and risk factors of NTDs among 1,000 participants (600 children above 15 years and 400 women aged 15–49) in rural Liberia using stratified and cluster sampling. Laboratory diagnostics, including Kato-Katz stool analysis, urine filtration, …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 1–7 Read article
-
The Burden of Empirical Therapy: Analyzing the Predominance of Broad-Spectrum Antibiotic Usage in Lower Respiratory Tract Infections
Abstract: Lower respiratory tract infections (LRTIs) remain one of the leading causes of morbidity and hospitalization worldwide, particularly among older adults, immunocompromised individuals, and patients with chronic respiratory disorders. These infections include conditions such as community-acquired pneumonia, hospital-acquired pneumonia, bronchitis, and acute infective exacerbations of chronic lung disease, all of which often require rapid clinical intervention. Because microbiological confirmation of the causative pathogen frequently takes 48–72 hours, clinicians generally initiate empirical …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 Read article
-
An Assessment of Nutritional Status among Students of Government Primary Schools in Semi-Urban areas of Chitradurga region
Abstract: Understanding children's nutritional status is crucial for enhancing future generations' quality of life, as evidenced by the elevated prevalence of stunting (36.2%), wasting (26%), and underweight (35.2%) in Karnataka according to the National Family Health Survey. This study aimed to assess the nutritional status, dietary habits, socio-economic conditions, and demographic profiles of students in Government primary schools in the semi-urban Chitradurga region. Using a validated questionnaire, data from 441 students …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 61–67 Read article
-
Geospatial Assessment of Land Use and Land Cover Changes in Debrigarh Wildlife Sanctuary, Odisha: A Twenty-Year Perspective
Abstract: Among the recorded dynamic processes on the surface of the earth is the change in land use and land cover (LULC) pattern as an outcome of several anthropogenic practices. Planning, development, and management of land for sustainable usage of land depend on plotting and tracing the vagaries in LULC. Anthropogenic activity, generally for forestry and food production, is altering the land surface. The steadily diminishing landscape also has tragic implications …
Published in Research & Reviews : Journal of Space Science & Technology · Vol. 14, Issue 2, 2025 · pp. 12–27 Read article
-
Technometric Portrait of Sri Vinod Dham, an Indo-US Engineer, Father of Intel Pentium Process: A Quantitative Analysis
Abstract: Vinod Dham is recognized as the ‘Father of Pentium Chip’ or ‘Father of Intel Pentium Process’ in the field of the computer industry, and as an Indo-American pioneer from Silicon Valley. He has contributed 10 research papers during 1982–1986, with an average of two papers per year. This study tries to analyze his contributions through a bibliometric study and draw his familiarity as a world-famous electronic technologist. Data has been …
Published in Research & Reviews : Journal of Statistics · Vol. 14, Issue 3, 2025 · pp. 16–25 Read article
-
Optimization of Fly Ash and Granulated Blast Furnace Slag (FA-GBFS) Mixes for Flexible Pavements
Abstract: This study investigates the compaction, strength, and permeability characteristics of fly ash (FA) stabilized with granulated blast furnace slag (GBFS) to determine the optimal mix proportions for geotechnical applications. Standard Proctor compaction, unconfined compressive strength (UCS), California Bearing Ratio (CBR), and permeability tests were conducted on FA-GBFS mixtures, with GBFS content varying from 10 to 50% by dry weight. The results indicate that increasing GBFS content enhances the maximum dry …
Published in Journal of Geotechnical Engineering · Vol. 12, Issue 2, 2025 · pp. 14–19 Read article
-
The Effect of Quicklime on The CBR Value of Soft Soil Stabilized with Nickel Slag and Aluminium Hydroxide
Abstract: The construction of road structures on soft soils is prone to structural damage due to the low bearing capacity of the soil under the load imposed by vehicles. Chemical stabilization is a popular method used to increase the bearing capacity of soft soils. This study aims to examine the effectiveness of soft soil stabilization using a mixture of lime, nickel slag, and aluminium hydroxide to enhance soil bearing capacity. The …
Published in Journal of Geotechnical Engineering · Vol. 12, Issue 1, 2025 · pp. 1–8 Read article
-
Development of Lightweight Chassis and Efficient Drivetrain for Formula Student Applications
Abstract: The chassis and drivetrain of a Formula Student vehicle are designed, analyzed, and optimized in this research study with an emphasis on manufacturability, performance, and safety. The project emphasizes the use of advanced engineering tools such as SolidWorks for computer-aided design (CAD) and ANSYS for structural analysis to evaluate the chassis under various dynamic conditions. The primary objective is to ensure that the driver remains safe inside the cockpit while …
Published in Journal of Automobile Engineering and Applications · Vol. 12, Issue 3, 2025 · pp. 1–17 Read article
-
Investigating The Influence of Sic Reinforcement on The Mechanical and Tribological Properties of PA12 Polymer Composites in SLS
Abstract: The study investigates the mechanical and tribological performance of neat PA12 polymer and SiC-reinforced PA12 polymer composites made via Selective Laser Sintering (SLS). To evaluate just how reinforcement has influence upon overall performance, we incorporated into the PA12 polymer matrix a constant amount of 5 wt.% of Silicon Carbide (SiC). Mechanical testing focused on both tensile and fatigue behavior and testers conducted it with a Servo-Hydraulic Multipurpose High-Capacity Fatigue Test …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 541–554 Read article
-
Metagenome-Informed Engineering of Monoclonal Antibodies: Mining Microbial Immunoglobulin-Like Domains for Ultra-Stable Therapeutics
Abstract: Metagenome-informed engineering represents an emerging strategy for improving the stability and functionality of monoclonal antibodies (mAbs) by leveraging the vast diversity of microbial immunoglobulin-like (Ig-like) domains (10,24). These domains, derived from uncultured bacteria and bacteriophages, exhibit exceptional thermostability, protease resistance, and structural resilience due to adaptation to extreme environments (29,30). This review highlights advances in metagenomic mining, structural characterization, and protein engineering that enable the integration of microbial Ig-like scaffolds …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
-
Design and Analysis of a Metal Lined Composite Overwrapped Pressure Vessel
Abstract: This study presents a comprehensive investigation into the mechanical behavior of a metal lined composite overwrapped pressure vessel, designed for high-pressure storage applications. The design approach is dependent upon fiber material constants and dome shape factor. The study begins with obtaining dome coordinates and maintaining winding angles according to a geodesic path equation. Thickness estimation for the portion of cylindrical shell and domes are determined through netting analysis and cubic …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 215–232 Read article
-
A Study to Assess the Prevalence of Self-medication and Its Associated Factors Among Pregnant Women in Selected Tertiary Care Teaching Hospital at Kuppam, Chittoor District, Andhra Pradesh
Abstract: Self-medication, the practice of using medications without a doctor's prescription, is a growing global public health issue, particularly in resource-limited settings. In pregnancy, self-medication can pose serious risks, including misdiagnosis, incorrect dosages, drug interactions, and prolonged use. This study aimed to assess the prevalence of self-medication, and the factors associated with it among pregnant women at a tertiary care teaching hospital in Kuppam, Chittoor district, Andhra Pradesh. A descriptive cross-sectional …
Published in International Journal of Midwifery Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 41–48 Read article
-
Design, Synthesis, and Spectroscopic Elucidation of 3-Methyl-1-Phenylpyrazol-5-One: A Cheminformatics-Aided Approach to Heterocyclic Drug Scaffolds
Abstract: Pyrazolone, a notable heterocyclic compound, has drawn increasing interest due to its broad pharmacological profile and structural versatility. The synthesis, characterisation, and biological assessment of new pyrazolone derivatives are examined in this work. A comprehensive review of existing synthetic strategies is presented, emphasizing green and efficient methodologies. Novel derivatives were synthesized using varied starting materials and catalytic systems, followed by structural confirmation through spectroscopic analyses, including NMR, IR, and mass …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 29–40 Read article
-
Thermo-Mechanical and Electrical Properties of Multi-Walled Carbon Nanotube-Enhanced Polyimide Composites for Aerospace Thermal Protection Systems
Abstract: Advanced aerospace thermal protection systems (TPS) require multifunctional materials that simultaneously provide high thermal stability, mechanical strength, and reliable electrical performance. Polyimide (PI) is widely used in aerospace structures due to its lightweight design and exceptional thermal durability, yet its low thermal conductivity and insulating behavior limit its effectiveness in heat dissipation and electromagnetic interference (EMI) shielding applications. This study addresses these limitations by developing multi-walled carbon nanotube (MWCNT)-reinforced polyimide …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 966–982 Read article
-
Performance Evaluation of Green Walnut Husk Waste Extract for Inhibiting Aluminium 8088 Corrosion in Acidic Solution
Abstract: The cumulative call for environmental and supportable corrosion inhibitors has obsessed curiosity in exploiting plant-based agronomic surplus resources. Presented research work discovers the corrosion inhibition probable of green walnut husk extract(GWH)—a normal and plentiful agro-waste—on Aluminium 8088 alloy in an acidic medium. Aluminium 8088, however identified for its corrosion resistance, is vulnerable to squalor in highly acidic settings, affectation trials in several industrial claims. GWH extract act as an ecologically …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 17, Issue 1, 2026 · pp. 44–60 Read article
-
Energetic and Exergetic Investigation on Vapor Compression Refrigeration System Using Ag₂O-R134a Nanofluid as Refrigerant
Abstract: This paper experimentally explored energetic and exergetic performance investigation of VCR System using Ag₂O-R134a Nanofluid as Refrigerant. The integration of silver oxide (Ag₂O) nanoparticles within polymer and composite materials offers promising avenues for enhancing the thermal and physical properties of advanced systems. The energetic and exergetic performance study of VCR were investigated with test parameters including compressor power consumption, cooling capacity, coefficient of performance (COP), discharge temperature, irreversibility in the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 279–287 Read article
-
Assessment of Vitamin D Levels Among Hashimoto and Hypothyroidism Disease in Iraq, A Comparative Study
Abstract: The thyroid gland is a small gland that regulates the body’s metabolism. It secretes the hormones that the body needs to maintain this process. People of different ages may be afflicted with thyroid diseases, including Hashimoto disease and hypothyroidism. The current study aimed to compare the levels of vitamin D among patients with Hashimoto’s disease and hypothyroidism coming to the Diabetes and Endocrinology Center in Al-Sadr Medical City in Najaf …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 77–83 Read article