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47 articles for “vaccine development”
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Infectious illnesses in areas of violence and among refugees
Abstract: Infectious illnesses are a huge and ongoing hazard in conflict zones and among refugee populations. This is because frail health systems, population relocation, and poor living conditions all come together to make transmission risks higher. Armed conflict undermines vital public health infrastructure, such as vaccination programs, disease surveillance, water and sanitation systems, and access to medical care, resulting in the resurgence and proliferation of avoidable and treatable illnesses. Refugee camps …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 36–40 Read article
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Host-Pathogen Coevolution: Implications for Immune Evasion and Pathogen Fitness
Abstract: The interaction between hosts and pathogens represents a continuous evolutionary struggle, shaping both microbial virulence and host immunity. Pathogens employ diverse strategies to evade immune surveillance, ranging from antigenic variation and molecular mimicry to hijacking of host immune checkpoints. Simultaneously, hosts refine innate and adaptive immune mechanisms to counteract infection and limit damage. This reciprocal adaptation, known as host–pathogen coevolution, influences pathogen persistence, transmission, and fitness, while also sculpting immune …
Published in International Journal of Pathogens · Vol. 2, Issue 2, 2025 · pp. 6–10 Read article
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Host Invasion to Immune Evasion: Emerging Concepts in Pathogen Virulence Strategies
Abstract: The interaction between hosts and pathogens represents a continuous evolutionary struggle, shaping both microbial virulence and host immunity. Pathogens employ diverse strategies to evade immune surveillance, ranging from antigenic variation and molecular mimicry to hijacking of host immune checkpoints. Simultaneously, hosts refine innate and adaptive immune mechanisms to counteract infection and limit damage. This reciprocal adaptation, known as host–pathogen coevolution, influences pathogen persistence, transmission, and fitness, while also sculpting immune …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 Read article
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Overcoming Obstacles to an HIV-1 Cure: Advances in Genome Editing, Immune System Reprogramming, and Viral Reservoir Elimination
Abstract: Human immunodeficiency virus type-1 (HIV-1) continues to represent a major global health challenge despite the remarkable success of antiretroviral therapy (ART). Although ART effectively suppresses viral replication and prolongs survival, it cannot eradicate the virus due to the persistence of long-lived latent reservoirs. In recent years, innovative therapeutic strategies have been explored with the aim of achieving either a functional remission or complete viral elimination. Advances in genome-editing technologies, particularly …
Published in International Journal of Virus Studies · Vol. 3, Issue 2, 2026 Read article
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Nutrition Induced Gut Microbiota Modulation in Food Animals: Implications for Viral Susceptibility, Shedding and Transmission Dynamics for Sustainable Development
Abstract: The gut microbiota has emerged as a central mediator linking host nutrition, immune competence, and vulnerability to viral pathogens in food animals. Diet is a primary driver of microbial community structure and function, influencing metabolite production, intestinal barrier integrity, and systemic antiviral immunity. Accumulating evidence indicates that nutrition induced modulation of the gut microbiota can substantially alter viral susceptibility, replication, and shedding patterns, with downstream effects on transmission dynamics within …
Published in International Journal of Virus Studies · Vol. 3, Issue 1, 2026 · pp. 46–56 Read article
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Disease: A Major Stumbling Block in the Growth of Aquaculture
Abstract: Aquaculture plays a crucial role in ensuring food security, fostering economic development, and providing recreational opportunities worldwide. However, the intensification of aquaculture practices has led to a surge in environmental challenges, including water pollution, soil acidification, eutrophication, chemical contamination, and the spread of diseases. Among these, diseases caused by bacteria, viruses, fungi, and parasites pose significant threats to the sustainability of global aquaculture. Despite the implementation of various diagnostic methods …
Published in International Journal of Marine Life · Vol. 1, Issue 1, 2024 · pp. 25–28 Read article
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Typhoid Fever: Etiology, Clinical Manifestations, Diagnosis, and Management
Abstract: Typhoid fever is a systemic and potentially life-threatening infectious disease caused by Salmonella enterica serotype Typhi, which primarily spreads through the fecal-oral route via ingestion of contaminated food and water. It continues to be a major global public health concern, particularly in developing and low-resource countries where poor sanitation, inadequate personal hygiene, and unsafe water supplies prevail. The disease is characterized by prolonged high-grade fever, abdominal discomfort, headache, loss of …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 1, 2026 · pp. 1–4 Read article