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132 articles for “toxicity test.”
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Acute and Chronic Toxicity of Fluoride and Aluminum on Plant and Animal Models
Abstract: Ecotoxicological studies revealed aluminum (Al2SO4. 24 H2O) to be more toxic than fluoride (NaF) on a battery of test organisms (EC/LC50 of Al = 0.308 1.46 ppm; F = 116.6 232.8 ppm). During chronic exposure (Al = 3 ppm, F = 10 ppm for 60 90 days), there was reduction in growth parameters of organisms at different trophic levels in a food chain such as producers {dry weights (6.7 29.0) …
Published in Research and Reviews: A Journal of Toxicology · Vol. 1, Issue 1-3, 2011 · pp. 1–19 Read article
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Genotoxicity Evaluation of Hospital Waste Waters: A Study Monitored by E.coli WP2 Assay
Abstract: The major sources of health-care waste are hospitals. A variety of substances such as pharmaceuticals, radionuclide and solvents are used in hospitals for medical diagnostics, disinfection and research work. After application, some of these substances and excreted non-metabolized pharmaceuticals by the patients enter into the hospital effluents. Indeed, some of these substances found in wastewaters are genotoxic and are suspected to be a possible cause of the cancers observed in …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 1, 2013 · pp. 6–11 Read article
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Evaluation Studies on Branded Edible Oils
Abstract: Epidemic dropsy is a clinical state which is caused due to argemone oil which is extracted from the prickly poppy seeds of Argemone Mexicana which are distributed and found everywhere. Argemone oil is used as an adulterated or substituent with sunflower oil and mainly also with mustard oil which is used for consumption leads to some the health disorders such as gall bladder cancer, necrosis, oedema, glaucoma, and cardiovascular disorder. …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 9, Issue 1, 2022 · pp. 27–33 Read article
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Acute Toxicity, Morphological Changes and Behavioral Responses Induced by Sodium Perfluorooctanoate in Indian Major Carp Labeo rohita (Ham.)
Abstract: Sodium perfluorooctanoate (NaPFO) is an anthropogenic ubiquitous environmental pollutant mainly used in textile, paper and ink industries, for specialized usage as emulsifiers, firefighting foam, lubricants etc. It finds entry into aquatic ecosystem through effluents from these industries. Static renewal bioassay test was conducted to determine 96 h LC50 of NaPFO on Indian major carp, Labeo rohita. The behavioral and morphological alterations in fingerlings were observed critically during the whole experiment …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 3, 2018 · pp. 1–8 Read article
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Assessment of Diuretic Activity of Hydroalcoholic Extract of Matricaria Chamomilla (Linn.) and Its Phytochemical Analysis with Emphasis on Toxicology
Abstract: While the traditional medicines are derived from medicinal plants, minerals and organic matter, the herbal drugs are prepared from medicinal plants only. This current research work will be very beneficial in figuring out the Matricaria chamomilla leaves extract diuretic effect by determining the ions and electrolyte excreted by the animals using ion selective channel inhibition. The phytochemical screening results revealed that the after which it was observed whether the alkaloids …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 1–10 Read article
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A Review of Different Polymer and Plasticizers
Abstract: Plasticizer and polymer are essential components in the pharmaceutical industry, especially when creating both cutting-edge and conventional drug delivery systems. The differences between synthetic, semi-synthetic, and all-natural polymers are examined in this review to highlight their diverse qualities and uses. When designing drug delivery systems to target areas, the choice of polymer is crucial. Because of their repeatability and adaptability, synthetic polymers are widely used in the creation of precision …
Published in International Journal of Membranes · Vol. 1, Issue 1, 2024 · pp. 1–7 Read article
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Phytochemical Screening, Proximate Analysis and Acute Toxicity Study of Ethanolic Extract of Launaea taraxacifolia on Visceral Organs of Albino Rats
Abstract: Despite increase in the acceptance of herbs for the treatment of certain diseases, there are limited information on the effectiveness, safety and toxicity of herbs. In this study, proximate analysis, phytochemical screening and acute toxicity studies on the herbal recipe, Launaea taraxacifolia were carried out. Constituents of Launaea taraxacifolia were extracted using ethanol. Phytochemical screening and proximate analysis were carried out on the extract. Fifteen (15) albino rats, divided into …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 3, 2014 · pp. 1–8 Read article
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Evaluation of Acute Toxicity Study of Some Indian Medicinal Plants against Anti-ulcer
Abstract: The acute toxicity study was carried out as per organization for economic co-operation and development guidelines 420. In acute toxicity study, the oral dose 150 mg/kg of body weight of animal of tested plant extract was administered to three groups in single dose groups in single dose and general behaviour, adverse effects were determined, the tested plant extract was administered orally for 14 days to three groups contained three animals …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 5, Issue 3, 2016 · pp. 22–29 Read article
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Engineering of PEG-b-PCL/Pluronic F127 Polymeric Composite Micelles for Controlled Co-Delivery of Docetaxel and Curcumin in Prostate Cancer Therapy
Abstract: Polymeric composite nanocarriers made from amphiphilic block copolymers are popular for their customisable architecture, self-assembly behaviour, and drug release control. A PEG-b-PCL/Pluronic F127 micellar composite was developed and tested as a multifunctional nanocarrier for docetaxel and curcumin administration.The amphiphilic block copolymers Pluronic® F127 and PEG-b-PCL were employed to generate polymeric micelles using solvent evaporation-assisted self-assembly. The optimised polymer composite showed good colloidal stability and uniform size distribution with a zeta …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 Read article
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QSAR Modeling Techniques A Comprehensive Review of Tools and Best Practices
Abstract: Quantitative Structure–Activity Relationship (QSAR) modeling has become an essential tool in drug discovery, toxicity assessment, and environmental chemistry. By correlating chemical structure with biological activity or toxicity, QSAR enables the prediction of compound behavior without extensive experimental testing. This approach not only saves time and resources but also supports ethical practices by reducing reliance on animal studies. The evolution of QSAR from basic linear models to advanced machine learning and …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 56–63 Read article
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Effects of Intraperitoneal Administration of ATRA on the Testis of Elastase Induced Emphysematous Rats
Abstract: Emphysema is the pathological manifestation primarily associated with lungs. However, there are evidences of extra-pulmonary manifestations related to emphysema. The inflammation developed during emphysema triggers the release of several inflammatory mediators, which affects the proximal as well as distal organs. The present study was designed to determine the effect of inflammatory spillage on testicular tissue of male Sprague dawley rats; moreover, the main focus was to assess the potential role …
Published in Research and Reviews: A Journal of Toxicology · Vol. 6, Issue 3, 2016 · pp. 1–12 Read article
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Flame-Retardant Polymeric Materials: Recent Advances and Future Directions
Abstract: This review explores essential flame-retardant polymers that play a vital role in various industries such as electrical & electronics, automobile, manufacturing, and firefighting. This review also highlights the latest progress in the design and synthesis of flame-retardant polymers, highlighting novel approaches such as the incorporation of nanomaterials, bio-based flame retardants, and the use of intumescent systems. Recent advancements include high-throughput screening, computational design, bio-based and sustainable flame retardants, self-healing materials, …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 125–132 Read article
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Development of Herbal Mosquitoes repellent candle
Abstract: Citronella oil and essential oil are commonly used for their insect-repellent properties. They’re important for creating natural insect repellents, candles, and sprays, offering a safer alternative to chemical-based products. Citronella oil is particularly effective against mosquitoes, making it invaluable for outdoor activities and protecting against insect-borne diseases like malaria and Zika virus. Its pleasant scent also adds to its appeal as a natural air freshener. In a mosquito repellent study, …
Published in Recent Trends in Cosmetics · Vol. 1, Issue 2, 2024 · pp. 8–12 Read article
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Acute Toxicity and Histopathological Evaluation of Polyherbal Formulations of Annona Squamosa, Zingiber Officinalis and Triticum Aestivum in Wistar Rats
Abstract: The relationship between dose and its effects on the exposed organism is of high significance in toxic evaluation. The present study was aimed for the safety assessment of methanolic extract of Annona squamosa, Zingiber Officinalis and Triticum aestivum as polyherbal formulations at different ratios in albino Wistar rats. Sighting study was conducted in one female rat by administering 300 mg/kg body weight of polyherbal formulation through oral gavage. There were …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 6, Issue 3, 2019 · pp. 1–7 Read article
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A Rare Cause of Parkinsonism—Manganese Toxicity
Abstract: A 43-year-old male presented with six months history of gradual onset and progressive bradykinesia, tremors of upper limbs and walking difficulty in the form of imbalance and short shuffling gait. He also had slurring of speech with hypophonia. Neurological examination revealed slow broken saccades, rigidity with cogwheeling, bradykinesia and short shuffling, festinant gait. He had action and postural tremors of upper limbs. Pull test was positive. Thus, a diagnosis of …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 9, Issue 1, 2019 · pp. 29–32 Read article
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Inhibitors for 2000 series from aluminum
Abstract: Corosion inhibitor is traditional procedure to protect under any weather. Use of inhibitors have formed thin coating film as well film having hydrofobic to super hydrophobic properties. Angle of contact for weather chemical is simplest test appeared to depend on stabilization of surface under interest. Inihibitor considerations have appeared from hybrid toxic-nontoxic to purely green inhibitors to reproduce as environmentally friendly usage. Inhibitors applicable during anodization has technical importance from …
Published in Emerging Trends in Chemical Engineering · Vol. 6, Issue 2, 2019 · pp. 28–38 Read article
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Comparison of the Effects of Voriconazole and its Nanogel form on Aspergillus Flavus Isolates in Vitro
Abstract: Aspergillus species are one of the most critical environmental fungi and are considered as a severe factor in causing hospital infections of foreign origin. Objective: Aspergillus flavus is a saprophytic and pathogenic fungus and is found all over the world. In clinical isolates, the voriconazole drug effectively affects more than 95% of Aspergillus isolates. These common drugs have limitations for maximum effect in patients, so nanomedicines are designed and manufactured …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 3, 2024 · pp. 14–20 Read article
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Review on Unveiling the Shadow of Hyperpigmentation
Abstract: Natural products offer promising solutions for treating skin pigmentation disorders due to their non-toxic properties and effective mechanisms of action. Studies highlight their safety and efficacy through methods such as cytotoxicity tests, tyrosinase activity assays, and melanogenesis inhibition evaluations. Advanced delivery systems like liposomes and nanoparticles further enhance their performance by improving solubility and skin penetration. Skin pigmentation disorders, influenced by factors such as UV radiation, hormonal changes, and inflammation, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 59–66 Read article
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Recent Advances in Nanobiotechnology: Applications and Future Perspectives
Abstract: Nanobiotechnology is a rapidly growing field that combines the principles of nanotechnology with biology, medicine, and biotechnology. This review article provides an overview of recent advances in nanobiotechnology and their applications in various fields, including drug delivery, imaging, biosensors, tissue engineering, and nanomedicine. The article also discusses the challenges and future prospects of nanobiotechnology. This review article provides an overview of recent advances in nanobiotechnology and their applications in various …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 24, Issue 3, 2022 · pp. 43–47 Read article
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Management of Acid Soils for Sustainable Crop Production in Eastern India
Abstract: AbstractSoil acidity poses a great problem for crop production due to very poor fertility status and nutrient imbalances in eastern and north eastern region and hence, it needs a special attention to address such acidity problems in relation to crop production. The integrated nutrient management system for the maintenance of soil fertility, sustainable agricultural productivity and improving profitability through the judicious and efficient use of mineral fertilizers especially secondary and …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 4, Issue 3, 2015 · pp. 22–32 Read article