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195 articles for “tool path”
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Prediction of Molecular Targets for Anthraquinone and Its Analogs for Treatment of Good Pasteur Syndrome
Abstract: Objective: In order to find prospective molecular targets for the treatment of Good Pasteur Syndrome (GPS), a rare autoimmune disease that affects the kidneys and other organs, computational methods and network pharmacology were applied in this work. The goal of the study is to identify particular human proteins that might interact with anthraquinone and its analogues as well as to uncover potential mechanisms of action by which these drugs might …
Published in International Journal of Bioinformatics and Computational Biology Read article
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Comparative Evaluation of GPBB and CK-MB in Early Diagnosis of Acute Myocardial Infarction in Diabetic and Non-Diabetic Patients
Abstract: Background: Acute myocardial infarction (AMI) continues to be a leading cause of morbidity and death among people worldwide. To lower the risk of problems, early and precise diagnosis is essential, particularly for diabetes patients. The study investigates the diagnostic value of Glycogen Phosphorylase BB (GPBB), a potential early biomarker of myocardial necrosis, and compares it with CK-MB, a widely used cardiac marker, in AMI diagnosis. Inflammatory markers (hs-CRP, IL-6, TNF-α) …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 33–37 Read article
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The Intersection of Bioinformatics and Cellular Function in Disease Modeling
Abstract: The integration of bioinformatics and cellular biology has revolutionized our understanding of disease mechanisms, offering unprecedented opportunities to model complex biological systems. Bioinformatics is an interdisciplinary field that merges biology, computer science, and statistics, offering advanced tools to analyze vast biological datasets. Cellular functions, including gene expression, protein interactions, and metabolic pathways, form the foundation of physiological and pathological states. Disruptions in these processes can result in diseases like cancer, …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 1–7 Read article
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A Comprehensive Tool for Authenticating Instagram Profiles Using Instaloader
Abstract: With the rapid growth of Instagram as a dominant social media platform, there is an increasing need for tools that allow users to extract, analyze, and monitor profile data efficiently. Instagram has become one of the leading platforms for personal branding, influencer marketing, business promotion, and public communication. As businesses and individuals seek to better understand their presence and influence on this platform, the need for reliable data extraction tools …
Published in Journal of Computer Technology & Applications · Vol. 16, Issue 2, 2025 · pp. 93–98 Read article
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Mass Spectrometry–Based Phosphoproteomic Markers to Predict Kinase Inhibitor Response in Solid Tumors
Abstract: Mass spectrometry-based phosphoproteomics has emerged as a powerful tool for predicting kinase inhibitor responses in solid tumors, offering direct functional insights into signaling pathways that surpass traditional genomic profiling by capturing dynamic kinase activities and adaptive resistance mechanisms. Technological breakthroughs, including data- independent acquisition (DIA), trapped ion mobility spectrometry (timsTOF), and efficient enrichment methods like TiO2 or IMAC, now enable comprehensive profiling of over 40,000 phosphorylation sites from limited clinical …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 2, 2026 Read article
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Analysis of Project Management Optimization Using CPM and PERT in a Dynamic Business Environment
Abstract: In the current fast-changing business environment, organizations must remain agile and strategically responsive to unpredictable challenges such as supply chain disruptions, shifting consumer demands, and evolving market trends. Project management techniques like the Critical Path Method (CPM) and the Program Evaluation and Review Technique (PERT) serve as valuable tools in helping businesses manage these complexities effectively. CPM is a time-focused method that identifies the longest sequence of dependent tasks in …
Published in Journal of Construction Engineering, Technology & Management · Vol. 15, Issue 3, 2025 Read article
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Performance Analysis of Bootstrapping Techniques to Overcome the Threshold Voltage Drop in NMOS Logic Design
Abstract: Abstract: In this paper, we study the concept of bootstrapping techniques and analyzed its performance in digital CMOS circuits. These bootstrapping circuits are used to increase the gate voltage of transistors so that drain node voltage can be pulled high to overcome the threshold voltage drop problem in NMOS logic design. Also discuss the drawback associated with voltage bootstrapping techniques in NMOS logic design that is sneak path problem between …
Published in Journal of Semiconductor Devices and Circuits · Vol. 6, Issue 1, 2019 · pp. 15–20 Read article
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In-Silico Studies of Phytochemicals from Allium sativum with H5N1 Protein in Avian Influenza
Abstract: Allium sativum or garlic is a medicinal plant that is reported for its applications in many biological activities, such as its antiviral, antidiabetic, and anti-inflammatory properties, etc. In this paper, the focus has been the identification of potential phytochemicals that can be extracted from Allium sativum that can act as a candidate for drug formation that possesses the capability to inhibit the H5N1 Avian Influenza, a type of highly pathogenic …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 2, 2024 · pp. 50–60 Read article
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Impact of Adaptive Learning, LMS, and Personalized Skill Development on Industry Recruitment Alignment
Abstract: This paper discusses the impact of adaptive learning on the development of skill and self-learning, and it portrays a methodology framework to design an adaptive learning system that works with industry recruitment objectives. The paper distinguishes different approaches to learning, namely teacher-centric and student-centric, rigid and adaptive, competitive and collaborative, and explains that each learner has their own learning style, preference, and level of knowledge and skill acquisition. The paper …
Published in Journal of Software Engineering Tools & Technology Trends · Vol. 12, Issue 1, 2025 Read article
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APPLICATIONS OF NANOTECHNOLOGY IN CROP IMPROVEMENT: NEW ERA OF AGRICULTURE
Abstract: It represents a transformative force in agriculture, promising to improve the productivity, yield, sustainability, and food security. This review paper focused on the certain advantages of nanoscience and nanotechnology in enhancing the agricultural productivity, disease management, and food safety. By manipulating different materials and objects at the nanoscale, researchers can develop advanced tools such as smart sensors and targeted delivery systems that improve nutrient absorption and combat plant pathogens. By …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 3, 2025 · pp. 46–54 Read article
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Sedimentation Analysis of Pench Dam using SWAT and SWAT-CUP Algorithm
Abstract: The Soil and Water assessment tool (SWAT) can be a very important tool to analyze the sediment as the determining the actual sediment deposit requires the very extensive observations of the sediment and it can be very much expensive and time consuming. The SWAT model along with little input of observe data can be used with proper calibration technique as the actual data for sedimentation and studying the changes in …
Published in Journal of Water Resource Engineering and Management · Vol. 8, Issue 2, 2021 · pp. 19–61 Read article
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Non-Enzymatic Glycation in Alzheimer’s and Parkinson’s Disease: A Molecular Approach to Pathology and Recent Advances
Abstract: Non-enzymatic glycation, a biochemical process by which reducing sugars spontaneously bind to proteins, leads to the formation of advanced glycation end-products (AGEs), which have emerged as critical contributors to the pathogenesis of several neurodegenerative diseases, particularly Alzheimer’s disease (AD) and Parkinson’s disease (PD). The accumulation of AGEs can significantly alter protein structure, stability, and function, triggering a cascade of detrimental effects, including increased oxidative stress, heightened neuroinflammation, and the promotion …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 36–41 Read article
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Exploring the viability of DIY mobile robots, a technical and economic perspective.
Abstract: This article is intended for on ramping of novices in mobile robotics and shine a new light on feasibility of home-brew robots. Readers are expected to use this resource as a take-off point from which they will get to know where to look and to what extent, along with some of our own recommendations. The topics covered include but not limited to, hardware selection, firmware programming, feedback control, system design, …
Published in Trends in Mechanical Engineering & Technology · Vol. 16, Issue 2, 2026 · pp. 34–41 Read article
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Virtual Reality in Education: A Transformative Tool for Enhanced Learning
Abstract: Virtual reality (VR) is a revolutionary technology in education, providing immersive and interactive experiences that can transform the learning process and enhance student engagement with educational content. This review paper provides an in-depth analysis of the applications of VR in education, exploring its effectiveness in enhancing learning outcomes, student engagement, and critical thinking skills. Additionally, the paper delves into the challenges and opportunities associated with integrating VR technology into educational …
Published in International Journal of Mobile Computing Technology · Vol. 2, Issue 1, 2024 · pp. 9–15 Read article
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SiRNA-Based Multivalent Vaccines: A Systematic Review of Potential Risks, Benefits, and Future Applications
Abstract: Background: Small interfering RNA (SiRNA) technology represents a promising innovation in vaccine development, especially for multivalent vaccines that can target multiple pathogens or antigenic variants simultaneously. siRNA-based vaccines offer a unique mechanism to induce specific immune responses, presenting an adaptable and potentially powerful tool for tackling infectious diseases and cancer. Methods: This systematic review synthesizes recent studies on siRNA multivalent vaccines, focusing on their immunogenicity, safety, and effectiveness. We reviewed …
Published in International Journal of Vaccines · Vol. 2, Issue 1, 2025 · pp. 43–49 Read article
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Recombinant Proteins and Nested Gene Regulation: Nutrient Driven Immune Response and Disease Resistance in Livestock
Abstract: Livestock production systems are increasingly challenged by infectious diseases, metabolic disorders, and environmental stressors that reduce productivity and compromise animal health. Advances in molecular biology and animal nutrition now offer new opportunities to strengthen disease resistance through integrated strategies that combine recombinant protein technologies, gene regulatory mechanisms, and nutrient mediated immune modulation. This review examines how recombinant proteins and nested gene regulation interact to shape nutrient driven immune responses in …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 · pp. 84–97 Read article
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Integrated, Geospatial Risk Assessment of Air, Water, and Soil Pollution Impacts on Agricultural Sustainability using Advanced Digital Technologies
Abstract: The systemic threat posed by the convergence of air, water, and soil contaminants represents a critical challenge to global agricultural resilience and food security. Traditional, site-specific pollutant monitoring methods are insufficient for capturing the dynamic, diffuse, and often nonlinear nature of environmental risk pathways that permeate agrarian landscapes. This study presents a robust framework for comprehensive risk assessment utilizing a synergistic suite of modern tools designed for spatial, temporal, and …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 3, Issue 2, 2025 · pp. 28–37 Read article
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Heterogeneous vs. Homogeneous Catalysis: Comparative Insights and Breakthroughs
Abstract: Catalysis, a pivotal process in chemical reactions, can be classified into two main types: heterogeneous and homogeneous catalysis. This comparative analysis delves into the distinctions, advantages, and breakthroughs in both domains. Heterogeneous catalysis, involving catalysts in a different phase than the reactants, is characterized by ease of separation and catalyst recovery, making it industrially favorable. Conversely, homogeneous catalysis, where catalysts and reactants share the same phase, offers superior selectivity and …
Published in Journal of Catalyst & Catalysis · Vol. 10, Issue 3, 2023 · pp. 1–7 Read article
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The Influence of Artificial Intelligence on Literary Criticism
Abstract: Artificial Intelligence (AI) has emerged as a significant force in reshaping contemporary literary criticism. Traditionally, the interpretation of literature has relied primarily on human-centered methods such as close reading, contextual analysis, and theoretical framing. However, the integration of AI-based techniques including Natural Language Processing (NLP), Machine Learning (ML), stylometry, and sentiment analysis has introduced new possibilities for examining literary texts at both micro and macro levels. These computational approaches allow …
Published in International Journal of Trends in Humanities · Vol. 3, Issue 2, 2026 · pp. 22–29 Read article
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AI EdTech Synergy: From Chalkboards to Smartboards
Abstract: Beyond textbooks and classrooms, AI paints a future from adaptive tutors to immersive realities. AI is not just a tool sculpted by algorithms but an architect of a learning revolution where knowledge becomes truly boundless. The convergence of AI marks an era of revolution in learning, promising individualized learning pathways, optimized evaluative metrics, interactive virtual pedagogies, and enhanced accessibility. This convergence examines the emergent field of AI-powered educational innovation, shedding …
Published in Journal of Open Source Developments · Vol. 12, Issue 3, 2025 · pp. 18–25 Read article