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101 articles for “renal”
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Problems among patients on hemodialysis in a tertiary care hospital
Abstract: Hemodialysis is an effective renal replacement therapy for patients with renal failure. However, these patients are chronic and under long term hemodialysis. The present study was carried out to identify the problems among patients on hemodialysis visiting artificial kidney unit, PGIMER, Chandigarh. A descriptive approach was used to enroll 50 patients using total enumeration technique who were meeting inclusion criteria. A self-structured interview schedule and modified Caregiver Burden Inventory were …
Published in Journal of Nursing Science & Practice · Vol. 8, Issue 2, 2018 · pp. 16–24 Read article
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Clinical Spectrum and Prognosis of Patients with Septic Shock
Abstract: Septic shock is the leading cause of mortality in hospital patients. Closer observation and early treatment can influence the outcome. The present study is undertaken to study the pattern of sepsis and the factors affecting morbidity and mortality in adult patients with septic shock in the ICU. Adult patients admitted in ICU, Mamata General Hospital, Khammam, with diagnosis of sepsis during one-year period from August 2012 to September 2013 were …
Published in Research and Reviews: A Journal of Health Professions · Vol. 4, Issue 1, 2014 · pp. 1–4 Read article
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An Insight to Hyponatremia in Cirrhosis: Pathophysiology and Management Approaches
Abstract: Cirrhosis is considered by systemic and splanchnic vasodilation that principals to extreme nonosmotic excretion of vasopressin. Hyponatremia is a mutual electrolyte irregularity in progressive liver disease that outcomes from the diminished capability of the kidney to excrete solute-free water that principals to “dilutional” hyponatremia water retention uneven to the retaining of sodium. Hyponatremia is mutual in cirrhosis. It frequently happens in a progressive phase of the disease and is related …
Published in Research and Reviews : A Journal of Immunology · Vol. 10, Issue 3, 2020 · pp. 30–46 Read article
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An Overview on the Management cum Treatment of Nephropathy in Type-1 Diabetes Mellitus
Abstract: The motive of this review is to keep updated with the medical nonfictions, the projected early natural arrangement of diabetic nephropathy, the theories behind the root of its pathogenesis pathophysiology, diagnosis and its supervision. Type 1 diabetes is an autoimmune disease characterized by advanced destruction of pancreatic beta cells by genetic and environmental factors which primes to an absolute necessity of insulin for survival and conservation of health; while Diabetic …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 9, Issue 3, 2020 · pp. 19–38 Read article
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A Review on Pierson Syndrome
Abstract: Pierson syndrome, also known as microcoria-congenital nephrosis syndrome, is a rare illness that mostly affects the kidney and eye. In 1963, Pierson et al. published the first description of this illness. A genetic mutation in the LAMB2 gene causes this disorder, which is responsible for producing the laminin-2 chain. The retina, neuromuscular junctions, glomerular and ocular basement membranes, and this laminin subunit are all significant components. Congenital nephrotic syndrome is …
Published in Research and Reviews: A Journal of Toxicology · Vol. 13, Issue 1, 2023 · pp. 10–14 Read article
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Herbal Drug Used in the Treatment of Diabetes: A Review
Abstract: Background: Diabetes mellitus is a chronic disease that occurs at the point when the pancreas is not able to produce insulin, or when the body cannot utilize the insulin it produces. Diabetes mellitus is a complex metabolic disorder that affects various systems of body such as visual, circulatory, renal and nervous system. Human beings depend upon plants for their various needs such as food, fodder, fuel, timber, fibres, dyes, gums, …
Published in Research & Reviews : Journal of Herbal Science Read article
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Late Onset Ataxia: A Case Report
Abstract: 57-year-old man with no prior history of any illness presented with subacute onset of gradually progressive gait ataxia, upper limb incoordination and speech issues. There was history suggestive of orthostatic hypotension and erectile dysfunction. On examination, there was normal cognition with gaze evoked nystagmus, scanning speech and limb incoordination in the form of past pointing, dysdiadochokinesia, and tandem walking abnormality suggestive of pan cerebellar involvement. The patient was evaluated with …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 1, 2024 · pp. 16–20 Read article
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Strategies in the Delivery of Nonsteroidal Antiinflammatory Drugs
Abstract: Non-steroidal anti-inflammatory drugs [NSAIDs]. are widely used for the management of pain, inflammation, and fever. However, their effectiveness is often limited by gastrointestinal side effects such as ulceration and bleeding, as well as systemic complications including renal toxicity and cardiovascular risks. To address these challenges, various strategies have been developed to improve the delivery of NSAIDs, aiming to enhance their therapeutic efficacy while minimizing adverse effects. This abstract provides an …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 44–61 Read article
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Concern for Public Health: Periodontitis
Abstract: Periodontitis, a severe form of gum disease, erodes the bone that supports teeth and results in tooth loss. It is caused by bacterial infection and inflammation of the soft tissues around the teeth. About 70% of people 65 years of age and older are affected, on average. Red, bleeding, sensitive gums, foul breath, and receding gums are hallmark indications. Depending on the severity, a full dental examination, the insertion of …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 1, 2024 · pp. 22–26 Read article
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Gene Annotation of Cancer Vaccine for Homo sapiens
Abstract: Objectives: Gene annotation helps us to deduce the structural and functional aspects of a gene that encodes for a functional protein in our body. Thus, by determining the coding sequence and gene location we can derive meaningful insights as to what these genes do in our body. In this study, an unknown gene, cancer vaccine for Homo sapiens has been studied and annotated. Methods: This study was based on a …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 1–14 Read article
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A Study on the Incidence and Prevalence of Cardiovascular Morbidity and Mortality in Patients Undergoing Maintenance Hemodialysis
Abstract: Cardiovascular Disease (CVD) is a major complication for patients with end-stage renal disease (ESRD) on Hemodialysis (HD), with the mortality rate from CVD being nearly 20 times higher than in the general population. As Chronic Kidney Disease (CKD) advances, patients accumulate both traditional and kidney-specific cardiovascular risk factors, such as hypertension, diabetes, fluid overload, electrolyte imbalances, and uremic toxins. These factors contribute significantly to the increased cardiovascular morbidity and mortality …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 56–66 Read article
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Morphine: A Pharmacological Perspective on Its Cancer Pain Management
Abstract: Morphine continues to be a key treatment in managing cancer pain because of its strong pain-relieving effects and established clinical history. Despite the emergence of alternative opioids and pain management therapies, morphine continues to be widely prescribed, particularly in palliative care settings. However, its use has been accompanied by concerns regarding tolerance, dependence, and adverse effects, which complicate long-term administration. This review explores the pharmacological aspects of morphine in cancer …
Published in Trends in Drug Delivery · Vol. 12, Issue 1, 2025 · pp. 1–8 Read article
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Comprehending and Managing Restless Leg Syndrome
Abstract: An need to move that arises during rest or is made worse by rest, that happens in the evening or at night, and that goes away or gets better with movement is the hallmark of restless legs syndrome (RLS), a frequent sensorimotor disease. The degree, frequency, and age of start of symptoms vary greatly; severe types can impair mood, quality of life, and sleep. Periodic leg movements are common in …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 1, 2025 · pp. 1–6 Read article
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Computational Identification of Antigenic Proteins and Epitopes in Hantavirus sp. for Drug Repurposing
Abstract: Hantavirus is an emerging virus that spreads from animals to humans and can cause serious illnesses like hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal syndrome (HFRS). there are no FDA-approved treatments available for these diseases. This study explores in-silico drug repurposing as a strategy to identify potential therapeutic candidates. The physicochemical, secondary structure, antigenicity, and post-translational modification analysis of hantavirus proteins – specifically the glycoprotein precursor, N protein, …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 20–26 Read article
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Navigating the Principles and Practice of Oral Anticoagulant Therapy: A Comprehensive Healthcare Guide
Abstract: Oral anticoagulant therapy plays a critical role in the prevention and treatment of thromboembolic disorders, including atrial fibrillation (AF), venous thromboembolism (VTE), and mechanical heart valve replacement. This research article aims to provide a comprehensive overview of the principles and practice of oral anticoagulant therapy, focusing on the mechanisms of action, pharmacokinetics, clinical indications, monitoring, and management of associated complications. The cornerstone of oral anticoagulant therapy includes vitamin K antagonists …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 76–82 Read article
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A summary continuation analysis evaluating the prevalence and predictors of diabetic retinopathy in newly diagnosed type 2 diabetic patients.
Abstract: Context: Diabetic retinopathy (DR), the leading cause of acquired blindness in adults, affects approximately 93 million people globally. It is a serious complication of type 2 diabetes, resulting from prolonged damage to the blood vessels in the retina. Although largely preventable and treatable, DR continues to be the main cause of vision loss among working-age adults and significantly impacts quality of life. While most studies on DR in Nepal have …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 · pp. 21–30 Read article
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Chronic Kidney Disease: A Comprehensive Review
Abstract: Chronic Kidney Disease (CKD) is a progressive condition characterized by a long-term decline in kidney function, leading to a gradual deterioration of the kidneys' ability to filter waste and maintain fluid balance. It is diagnosed when the Glomerular Filtration Rate (GFR) falls below 60 ml/min/1.73 m² or when there is evidence of kidney damage (such as proteinuria) lasting for 3 months or more. The most common causes of CKD are …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 37–42 Read article
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Integration of Biomarkers in III and IV CKD Patients for Evaluation of Their Predictive Value for CVD in CKD Patients
Abstract: Background: Chronic kidney disease (CKD) is presently characterized by the presence of proteinuria and/or a diagnosis of renal impairment. The worldwide significance of CKD is underscored by the fact that its prevalence and incidence have doubled over the past three decades. This paper provides an overview of the existing evidence regarding biomarkers in individuals with CVD or CKD, with a particular focus on the emerging biomarkers (i.e., eGFR, sALB, UACR, …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 3, 2025 · pp. 1–12 Read article
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Pharmacological Comparison of Turmeric and Non-Steroidal Anti-Inflammatory Drugs in Pain Relief
Abstract: Pain is one of the most frequently encountered clinical symptoms affecting millions globally and is typically treated pharmacologically with nonsteroidal anti-inflammatory drugs (NSAIDs). However, long-term use of NSAIDs is associated with adverse effects such as gastrointestinal, renal, and cardiovascular issues. In recent years, turmeric and its main active compound, curcumin, have received considerable attention for their reported anti-inflammatory, analgesic, and antioxidant properties as natural therapeutic options. This review seeks to …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 1, 2026 · pp. 19–28 Read article
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Review on the Efficacy of Ayurvedic Formulations in Diabetes Management
Abstract: Diabetes mellitus is one of the most prevalent metabolic disorders globally, characterized by persistent hyperglycemia resulting from defects in insulin secretion, insulin action, or both. It leads to serious complications affecting the cardiovascular, renal, and nervous systems, imposing a significant health and economic burden. In Ayurveda, diabetes is described as Madhumeha, a subtype of Prameha, primarily caused by the vitiation of Kapha dosha, Meda dhatu (fat metabolism), and Agnimandya (impaired …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 1, 2026 · pp. 16–22 Read article