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84 articles for “pathogens”
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Exploring the properties and extraction of neem leaves
Abstract: Neem (Azadirachta indica) is a versatile medicinal plant, for its diverse therapeutic properties. This abstract provides a comprehensive overview of recent research focusing on phytochemical analysis, biochemical characterization, and antimicrobial susceptibility testing of Neem extracts. Utilizing the different from of chemical used in it, phytochemical analysis identified a plethora of secondary metabolites within Neem, including alkaloids, flavonoids, terpenoids, steroids, saponin, tannins, quinone, and phenolic compounds, indicative of its complex chemical …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 2, 2024 · pp. 32–39 Read article
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DMARDs, Biologic Agents and Novel Experimental Strategies in The Treatment of Rheumatoid Arthritis
Abstract: An inflammatory and autoimmune disease, rheumatoid arthritis (RA) causes severe pain and inflammation in affected areas of the body. According to the report, there is no known cure for RA. Therefore, reducing discomfort and halting future harm must be the goals of present therapy. For the purpose of prevention and to reduce disease activity in RA patients, significant success has been achieved with the continued development of disease-modifying antirheumatic drugs …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 14–24 Read article
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Development of Anti IgG Polyclonal Antibody Against Canine IgG and Their Roles in Diagnostic Purposes
Abstract: IgG plays an important part in immunological studies and also in living bodies for providing secondary immune response which triggers as passive immunization against harmful pathogens in dogs. Purpose: The aim of this investigation is to separate, identify, and refine immunoglobulin G from canine serum. Methods: Ammonium sulphate precipitation was used to separate the dog's serum, which was then concentrated over night in a dialysis bag inside of a refrigerator. …
Published in International Journal of Vaccines · Vol. 1, Issue 2, 2024 · pp. 01–06 Read article
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A Narrative Review on an Insight of Herbal Origin Drugs and Their Traditional Medicine Formulations for the Treatment of Nephrolithiasis
Abstract: Ethnopharmacological relevance. There is no satisfactory treatment at present to cure or prevent kidney stone recurrences using predictable medicines. There are several marketed formulations in Ayurveda, Unani and Homeopathic Traditional Medicines (TM) have potential lithotriptic effects and clinical applications. In India, prevalence rates of complementary and alternative medicine (CAM) for the treatment of nephrolithiasis are being estimated at 63.9%. Aim of the review This review article intended to scientifically documented …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 1, 2024 · pp. 14–30 Read article
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Unraveling Metagenomics: A Comprehensive Diagnostic Approach for COVID-19
Abstract: The COVID-19 pandemic has brought attention to the need for rapid, accurate, and scalable diagnostic techniques. Metagenomics, a powerful technique that enables the comprehensive analysis of genetic material from complex microbial communities, has emerged as a promising diagnostic approach for COVID-19. This article elucidates the principles of metagenomic sequencing, highlighting its ability to detect viral RNA directly from clinical samples without prior knowledge of the pathogen. Furthermore, we discuss the …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 2, 2024 · pp. 19–28 Read article
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Japanese Encephalitis and Dengue Fever Co-infection
Abstract: Dengue virus (DENV) and Japanese encephalitis virus (JEV) are two significant pathogenic viruses that can cause severe encephalitis. Dengue and Japanese encephalitis are vector-borne illnesses.Arboviruses that are carried by mosquitoes are significant India's causes of death and morbidity The rainy season, when the vector population grows, is when both dengue and Japanese encephalitis transmissions peak. We still don't fully understand how the CNS is involved in dengue and Japanese encephalitis …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 2, 2024 · pp. 14–18 Read article
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Viral Chronicles: The Ever-Evolving Saga of COVID-19
Abstract: Coronaviruses, belonging to the family of RNA viruses, have recently captured global attention owing to their remarkable ability to infect a diverse array of species, ranging from animals to humans. These viral agents, recognized by their characteristic crown-like morphology when observed through electron microscopy, have a historical association with zoonotic diseases. Previous examples include Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV). The term "Corona" …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 16–25 Read article
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Antibiotic Resistance Profiles of Salmonella Isolated from Al-Gharraf River and Iraqi Sewage
Abstract: Salmonella is a Gram-negative bacterium belonging to the Enterobacteriaceae family. It has a rod-shaped (bacillus) structure. Salmonella is a prominent contributor to gastrointestinal sickness worldwide. In addition, it is the causative agent of more systemic severe disorders such as typhoid and paratyphoid fevers. Salmonella is primarily recognized as pathogens transmitted by water and food to people and animals. Salmonella is often found in water-related epidemics, even though it is routinely …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 1–10 Read article
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Zn Doped CuO Nanoparticles for Increasing the Longevity of The Agricultural Products †
Abstract: Nanotechnology is an enabling technology at the service of mankind. Indeed, enhancing the long-term storage of agricultural products (post-harvest during transportation and storage) in general and apples and tomatoes, in particular, is a challenge. Zn-doped CuO is a proven nanomaterial with special ability to kill plant pathogens as well as a variety of microorganisms (bacteria, virus, and fungus). Much of the review is focused on the landmark papers published by …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 1, 2024 · pp. 14–29 Read article
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Gut Microbiome Dysbiosis During Metabolic Disorders: Diabetes
Abstract: Understanding the intricate interplay between gut microbiome dysbiosis and diabetes is crucial due to the escalating prevalence and impact of diabetes mellitus globally. This comprehensive review examines the current understanding of this relationship, elucidating how alterations in the gut microbiome composition contribute to diabetes pathogenesis by influencing metabolic homeostasis, immune regulation, and insulin resistance. Dysregulation of gut microbial communities leads to shifts in diversity and abundance, exacerbating chronic low-grade inflammation …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 56–75 Read article
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Defensive Mechanisms and Key Strategies with Its Specified Role in Mulberry Silkworm (Bombyx mori L.)
Abstract: Silkworms (Bombyx mori L.) possess a variety of defense mechanisms that play a vital role in protecting them against microbial infections and environmental stressors. These defense systems are primarily innate, relying on cellular and humoral responses. Cellular defenses include hemocytes which are responsible for processes like phagocytosis, encapsulation, and nodule formation. Humoral responses involve the production of antimicrobial peptides (AMP’s), such as cecropins, moricins, and lysozymes, which target invading pathogens. …
Published in International Journal of Insects · Vol. 1, Issue 2, 2024 · pp. 10–14 Read article
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Development of a Novel Therapeutic Approach Using RNA Interference for Targeting Viral Genes
Abstract: RNA interference (RNAi) is a ground breaking therapeutic strategy that holds immense promise for targeting viral genes in the treatment of viral infections. This approach leverages the natural gene-silencing mechanisms of RNAi to inhibit viral replication and expression at the molecular level, providing a precise and adaptable method to counteract viral pathogens, including influenza, HIV, and hepatitis viruses. Recent advancements in RNAi technology have enabled the development of highly specific …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 12–22 Read article
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Review of Current Trends in Vaccine Development against Zoonotic Viruses: Challenges and Innovations
Abstract: The emergence of zoonotic viruses poses a significant threat to global public health, necessitating rapid advancements in vaccine development. This review highlights the current trends and innovative strategies employed in the creation of vaccines against zoonotic pathogens, including but not limited to viruses responsible for diseases such as Ebola, Zika, Nipah, and more recently, SARS-CoV-2. We discuss various vaccine platforms, including inactivated, live attenuated, mRNA, and viral vector vaccines, focusing …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 1–11 Read article
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FMR1 Key Biomarker in Fragile X Syndrome- A Comprehensive Review
Abstract: Fragile X Syndrome (FXS) is a complicated neurodevelopmental condition that causes intellectual disabilities, behavioural issues, and a variety of physical symptoms. Central to understanding FXS is the Fragile X Mental Retardation 1 (FMR1) gene, pivotal in the disorder's pathogenesis. This review examines FMR1 as a key biomarker in FXS, drawing on recent research insights. The FMR1 gene, situated on the X chromosome, encodes the fragile X mental retardation protein (FMRP), …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 8–18 Read article
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Harnessing Ethylene and Brassinosteroids for Enhanced Agricultural Productivity and Food Quality
Abstract: This study provides a comprehensive review of the roles of ethylene and brassinosteroids, two vital hormonal regulators in plants, focusing on their impact on fruit ripening, stress responses, and overall plant growth. Ethylene, a gaseous plant hormone, is recognized as a key regulator in various physiological processes, particularly in the maturation of fruits. Its involvement in the ripening process has profound implications for agricultural practices, as it directly influences the …
Published in International Journal of Trends in Horticulture · Vol. 1, Issue 2, 2024 · pp. 29–32 Read article
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Efficacy Evaluation of Trichoderma Harzianum, T. Viride, & T. Asperellum: Eco-Biocontrol Agents Against Dry Rot of Potato in Pakistan
Abstract: Fusarium sambucinum is one of the most aggressive fusarium species initiating potato dry rot disease around the world and causing significant economic losses. To alleviate reliance on synthetic fungicides as their long-term use may lead to fungal resistance, biocontrol assays against threatening fungal diseases hold significant importance as an eco-friendly management approach. Antagonists are gradually becoming hotspots and hold broad applicable prospects. Trichoderma harzianum, T. viride, and T. asperellumwere screened …
Published in International Journal of Fungi · Vol. 2, Issue 1, 2025 · pp. 46–50 Read article
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Common Diseases of Silkworm and Their Management – A Comprehensive Overview
Abstract: Silkworms (Bombyxmori L.), pivotal to the sericulture industry, are susceptible to various diseases that significantly impact cocoon production and quality. Common silkworm diseases include viral, bacterial, fungal, and protozoan infections. Prominent viral diseases, such as nuclear polyhedrosis (NPV) and cytoplasmic polyhedrosis (CPV) often cause mass mortality in larvae. Bacterial diseases, like flacherie, are typically induced by poor hygiene and environmental stress. Fungal infections, including muscardine caused by Beauveria bassiana, proliferate …
Published in International Journal of Insects · Vol. 2, Issue 1, 2025 · pp. 22–28 Read article
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Study on Chemical Insights into Alzheimer's Disease: Amyloid Beta and Tau Protein Interactions
Abstract: Background: Alzheimers disease (AD) is the most prevalent form of dementia, affecting millions of individuals worldwide and posing significant challenges to healthcare systems. The disease is characterized by a gradual decline in cognitive functions, particularly memory, reasoning, and the ability to perform daily activities. Aim & objective: To study chemical insights in alzheimers disease, especially amyloid beta and tau protein interactions Results & discussion: The results of this review highlight …
Published in International Journal of Brain Sciences · Vol. 2, Issue 1, 2025 · pp. 37–46 Read article
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Microorganisms used in aquaculture
Abstract: Microorganisms play a vital role in the health and sustainability of aquaculture systems, contributing to water quality management, disease control, and the overall productivity of aquatic farms. Beneficial microorganisms, including bacteria, fungi, algae, and probiotics, are increasingly recognized for their positive impact on aquaculture operations. These microorganisms can enhance nutrient cycling, promote the breakdown of organic waste, and reduce the need for harmful chemicals, thus improving the environmental footprint of …
Published in International Journal of Marine Life · Vol. 2, Issue 2, 2025 Read article
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Emerging Therapies in Respiratory Tract Infections: Current Advances and Future Perspectives
Abstract: The impact of respiratory tract infections (RTI) as a global public health problem continues to be high morbidity and mortality rates. The development of novel therapeutic approaches stemmed from the fact that conventional treatment strategies, antibiotics, antivirals, antifungals etc. have become increasingly ineffective because of rise of antimicrobial resistance (AMR). Next generation therapies, such as novel antimicrobial agents, host directed therapies and novel drug delivery systems have come on the …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 17–25 Read article