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101 articles for “key factors”
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Diet-Gene Interactions in Farm Animals: Molecular Dynamics, Gene Expressions, Signalling Pathways and Precision Nutrition for Sustainable Productivity
Abstract: Diet-gene interactions represent a central mechanism through which nutrition influences growth, health, and productivity in farm animals. Recent advances in molecular biology and genetics have revealed that nutrients act not only as metabolic substrates but also as signalling molecules capable of modulating gene expression, cellular pathways, and epigenetic regulation. This review synthesizes current knowledge on the molecular dynamics of nutrient utilization in farm animals, with emphasis on nutrigenomic responses, nutrient …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 Read article
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High Expectations, Low Outcomes: Exploring Coping Mechanisms and Psychological Adaptation
Abstract: This review paper explores the psychological impact of high expectations and low outcomes, focusing on coping mechanisms to manage the resulting emotional and mental challenges. The anticipation of a guaranteed future often elevates self-esteem and brings a state of emotional ecstasy. When individuals perceive the future in alignment with their personal terms and conditions, they experience heightened happiness and acceptance of life. This sense of assurance often influences risk-taking capacity, …
Published in International Journal of Trends in Humanities · Vol. 2, Issue 2, 2025 · pp. 31–38 Read article
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DFT/Data Guided Predictive Modelling of Absorption Maxima in the OLED Rubrene Derivatives
Abstract: This study investigates the optical properties of rubrene derivatives to develop an accurate predictive model for absorption maxima using computational chemistry and chemoinformatic techniques. We benchmarked various quantum chemical methods, identifying that the M06-2X/aug-cc-pVDZ method in dichloromethane (DCM) provided the strongest correlation with experimental data. Key molecular descriptors such as band gap, ionization potential, and electrophilicity index were calculated and analyzed using principal component analysis (PCA) to identify significant factors …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 41–56 Read article
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Simulation and Analysis of Battery Pack Using the Multi Scale Multi-Domain Battery Model
Abstract: The creation of sophisticated simulation models has been made necessary by the need for reliable and effective battery packs in energy storage systems and electric vehicles. This study focuses on the simulation and analysis of battery packs using a multi-scale multi-domain battery model. The model enables a thorough knowledge of battery pack behavior across a range of operating situations by integrating the electricity, thermal, and mechanical domains. Multi-scale modeling bridges …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 2, Issue 2, 2024 · pp. 31–46 Read article
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Stingless Honeybee’s Rare Sugar and PCSK 9 - LDLR Interaction, A New Hope for Hormone Dependent Breast Cancer Patients – An In-silico Study
Abstract: Hypercholesterolemia is a lipid disorder characterized by elevated levels of low-density lipoprotein (LDL), commonly known as "bad" cholesterol. This condition is a significant risk factor in the development and progression of hormone-dependent breast cancer, as well as in the emergence of resistance to hormonal therapy. One of the key regulators of cholesterol metabolism is the proprotein convertase subtilisin/kexin type-9 (PCSK9) protein, which facilitates the degradation of the LDL receptor (LDLR) …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 1–6 Read article
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Molecular Docking of Nigella Sativa Phytocompound as Inhibitors of Transcription Factors NF-KB Implicated in Rheumatoid Arthritis
Abstract: Objectives: Nigella sativa, a plant considered around the world as the most treasured nutrient-rich herb for centuries together in different civilizations, is exceptionally known for its high levels of antioxidant properties. Free radical intensification due to oxidative stress plays a key role in the pathogenesis of rheumatoid arthritis by activating the NF-KB protein that regulates the expression of the genes involved in inflammation. Methods: This study involves in-silico approach to …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 42–55 Read article
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Divorced Women Attitudes Towards Remarriage: A Qualitative Approach
Abstract: The current study aimed to investigate the attitudes of divorced women regarding remarriage and to comprehend the diverse factors that shape their viewpoints. The research population comprised divorced women, and a purposive sampling method was employed to select participants. Data were collected from ten divorced women through semi-structured interviews, allowing for in-depth exploration of personal experiences and viewpoints. A qualitative research design was adopted to capture the complexity of individual …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 1, 2026 · pp. 1–14 Read article
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From Rural to Urban: Understanding Taobao Villages to Redress Planetary Urbanisation
Abstract: This study examines Taobao Villages as an innovative model of urbanisation under China’s planetary urbanisation framework. These rural communities, driven by the rise of e-commerce and digital infrastructure, have successfully integrated into the broader urban ecosystem by reconfiguring their historical socio-spatial legacies. Through Lefebvre’s spatial triad framework, the research identifies three key historical legacies that underpin this transformation: (1) Collective Production Practices: Rooted in socialist collectivisation, these legacies include organisational …
Published in International Journal of Urban Design and Development · Vol. 3, Issue 1, 2025 · pp. 1–7 Read article
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Investigating Factors Associated to Speech and Language Development Problem Among Under-five Children in Bangladesh: A Cross-Sectional Study
Abstract: Speech and Language Delay (SLD) is a developmental disorder characterized by a lag in a child's acquisition and use of spoken language compared to typical developmental milestones. It is a significant developmental concern with profound implications for cognitive, social, and academic outcomes. The objective of this study is to explore the factors associated to SLD in children and early intervention of the problem to support the children who need special …
Published in International Journal of Children · Vol. 2, Issue 2, 2025 · pp. 1–12 Read article
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Self-Help Group and Rural Women’s Socioeconomic Empowerment in India: An SDG Perspective
Abstract: This research examines the impact of Self-Help Groups (SHGs) on rural women in Khurda District, Odisha, and their contribution to achieving the United Nations’ Sustainable Development Goals (SDGs). The central aim of the study is to understand whether participation in SHGs helps women improve their socioeconomic conditions and move closer to global development goals, such as poverty reduction, food security, better health, improved education, and gender equality. To assess this, …
Published in International Journal of Rural and Regional Development · Vol. 4, Issue 1, 2026 · pp. 38–48 Read article
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Floating Cities from Concept to Creation :Neighbourhood Guide to the Future Development
Abstract: Today cities are overpopulated and only 40% of space is left to house the world's population by 2050. Due to ever rising sea level 90% of coastal cities will be affected by flooding by the end of the century. This research aims to study about the floating city as a substitute. Floating cities shape to construct all of the infrastructure required for a water-based metropolis while also providing contextual space …
Published in International Journal of Urban Design and Development Read article
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An Overview of Construction Market of Sri Lanka
Abstract: This paper provides an overview of the construction market in Sri Lanka, with a focus on the Colombo region. It discusses the strengths, weaknesses, opportunities, and constraints of the construction market in the country. The main drivers of the construction sector are identified, including urbanization and infrastructure development. The paper explores the ease of embarking on international construction projects within the Colombo region, noting that while the Sri Lankan government …
Published in International Journal of Rural and Regional Development · Vol. 1, Issue 1, 2023 · pp. 58–64 Read article
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Genetic Counseling: A Pathway to Understanding and Managing Inherited Health Risks
Abstract: Genetic counseling is an essential aspect of personalized medicine that supports individuals and families in understanding the implications of inherited health conditions. With the rising prevalence of genetic disorders and advancements in genomic technologies, counseling provides critical insights into risk factors, diagnostic options, and informed decision-making. This paper explores the classification of genetic disorders, major genetic and environmental causes, and the expanding role of genetic counseling within India’s culturally diverse …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 4, Issue 1, 2026 · pp. 10–14 Read article
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Extant Roofing Pattern and Early Decay of Residential Buildings in Port Harcourt Municipality, Rivers State
Abstract: The design and construction pattern of roofs in the tropical environment like Port Harcourt Municipality, Rivers State is a major factor that determined how functional and the life span of building components and materials. In recent time residential building components and materials had been observed to decay earlier than expected due the existing roofing pattern. This study is aimed at assessing the extant roofing pattern and identified factors responsible for …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 3, Issue 2, 2025 · pp. 16–24 Read article
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Personalized Nutrition and Exercise: Pioneering the Path to Precision Medicine
Abstract: Preventive healthcare is about to undergo a major shift thanks to the personalised exercise and nutrition paradigm, which is based on precision medicine concepts. In order to create tailored recommendations for improving health outcomes and preventing chronic diseases, this article explores the integration of genetic profiling, metabolic evaluation, and lifestyle factors. A person's response to food and exercise depends heavily on genetic and metabolic variances, which emphasises the need of …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 2, 2024 · pp. 42–46 Read article
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Crystal Engineering Strategies for Tailoring Mechanical Properties of Structural Materials
Abstract: Crystal engineering has emerged as a promising approach for designing materials with tailored mechanical properties, enabling advancements in various fields such as aerospace, automotive, and construction. This review examines the diverse strategies employed in crystal engineering to manipulate the mechanical behavior of structural materials. One key strategy involves controlling the crystal structure at the atomic level through techniques such as alloying, doping, and phase transformations. Alloying introduces foreign atoms into …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 1, 2024 · pp. 01–06 Read article
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Epidemiology and transmission of infectious diseases study using Machine learning
Abstract: Infectious diseases remain a formidable global health challenge, characterized by rapid evolution and complex transmission dynamics that often outpace traditional epidemiological surveillance and response mechanisms. This study investigates the transformative potential of machine learning (ML) methodologies to enhance our understanding and prediction of infectious disease epidemiology and transmission. Leveraging diverse datasets—including clinical records, genomic sequences, environmental factors, social mobility data, and real-time digital footprints—we studies and presented various ML models …
Published in International Journal of Pathogens · Vol. 2, Issue 2, 2025 Read article
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Bridging the Gap: Exploring the Social and Economic Dimensions of Gender Equality
Abstract: Gender equality is a fundamental human right and a critical prerequisite for sustainable social and economic development. Despite notable progress in recent decades, significant disparities persist worldwide, particularly in the social and economic domains. This paper explores the multifaceted nature of gender inequality, examining how structural, cultural, and institutional barriers continue to shape unequal access to resources, opportunities, and decision-making power. By analysing key sectors such as education, healthcare, labour …
Published in Recent Trends in Social Studies · Vol. 3, Issue 1, 2026 · pp. 19–24 Read article
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Factors Affecting Mammalian Embryo Culture: A Detailed Review
Abstract: Human IVF has made remarkable progress, but optimizing the in vitro environment remains essential and crucial for supporting embryo development and improving overall clinical outcomes in assisted reproductive technologies (ART). Even with advances in complex culture media, incubator design, and laboratory workflows, embryos grown outside the body are still exposed to chemical and physical stressors that can significantly affect their developmental potential. In this review, we discuss key chemical stressors, …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 Read article
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Molecular Pharmacokinetics and Structural Docking of Phenolic Acids for Targeting NF-κB Pathway Components in Inflammation and Fibrosis: A Computational Approach Toward Therapeutic Discovery
Abstract: Inflammation and Fibrosis are critical pathological processes associated with various chronic diseases, often mediated by the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway. This study investigates the therapeutic potential of phenolic acids as modulators of the NF-κB pathway, aiming to identify novel ligands that can effectively interact with key components of this signaling cascade. A comprehensive computational approach was employed, utilizing molecular docking, pharmacological screening, and post-docking …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 14–31 Read article