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1223 articles for “insights”
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An Insight to Diagnosis and Management of Druginduced Hepatotoxicity: An Overview
Abstract: (ADRs) Adverse Drug Reactions are constitute and mutual chief health problem. Throughout the last period liver toxicity has remained one of the most recurrent reasons for pharmacovigilance protection intelligences and the withdrawal from the marketplace of an accepted medicinal product. Liver is a main organ elaborate in the systemic deposition and decontamination of exogenous and endogenous ingredients. Liver disfunction challenges not only health care specialists but also the pharmaceutical manufacturing …
Published in Trends in Drug Delivery · Vol. 8, Issue 2, 2023 · pp. 39–54 Read article
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Dengue in India : Insights in the Indian Context
Abstract: The mitigation of infectious diseases in India, notably Dengue, assumes pivotal importance due to their significant repercussions on human and animal health, thereby imposing a considerable burden on the healthcare infrastructure. This review underscores the ongoing initiatives in infectious disease management, endorsing the implementation of a comprehensive healthcare strategy. Emphasis is placed on the augmentation of reporting mechanisms through the integration of IgM detection kits, advocating for heightened investments in …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 2, 2024 · pp. 10–13 Read article
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Vyanga, Present-Day Challenge: Insights from Toxicological Standpoint
Abstract: The condition of Vyanga can have significant repercussions, as facial disfigurement not only impacts an individual's psychological and social well- being but also hampers their overall contribution to society. This can result in reduced productivity, impaired social functioning, and diminished self-esteem. In classical Ayurvedic texts, Vyanga is categorized under Kshudrarogas, representing minor disorders with straightforward causes and symptoms. However, in certain instances, these conditions can lead to noticeable cosmetic impairments, …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 11–16 Read article
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Deciphering Th-Related Gene Interactions in Chronic Spontaneous Urticaria: Bioinformatics Insights and Drug Affinity Exploration
Abstract: Objective: There has been a great deal of interest in how inflammatory dermatosis and The cell interact, but the etiopathogenesis of chronic spontaneous urticaria (CSU) is still inadequately comprehended. Through bioinformatics techniques, the purpose of this work is to elucdate the molecular mechanism underlying Th-related genes in CSU and seeks to find the highest affinity drug. Methods: The CSU RNA expression profiling dataset provided the basis for the investigation. The …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 1–15 Read article
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Unravelling the Impact of AI: Insights into Pattern Recognition and Image Processing
Abstract: Apart from its academic origins, the evolution of Artificial Intelligence (AI) has emerged as a notable influence in shaping our daily experiences. Artificial intelligence, which focuses on domains such as image processing and pattern recognition, encompasses a vast array of topics, including its complex applications, obstacles, and societal repercussions. Machine Learning, Natural Language Processing, Computer Vision, Robotics, Expert Systems, Knowledge Representation, and AI Ethics are among the domains in which …
Published in Journal of Image Processing & Pattern Recognition Progress · Vol. 11, Issue 1, 2024 · pp. 1–7 Read article
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An Insight into Childhood Malignancy
Abstract: Childhood cancers represent a significant public health concern, affecting a vulnerable population with unique biological and developmental characteristics. The aim of this article is to describe the main causes and different types of malignancies in childhood. By understanding the contributing factors towards malignancy in childhood one can plan for the preventive measures and early diagnosis and treatment modalities can be adopted. Even though the treatment patterns have improved, people are …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 07–12 Read article
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Computational Analysis of Non-Newtonian Blood Flow through Bifurcated Coronary Artery: Insights into Hemodynamics and Wall Shear Stress
Abstract: This abstract presents a study on the computational fluid dynamics (CFD) simulations of blood flow through a bifurcated coronary artery using non-Newtonian fluid model. The objective of this study is to investigate the hemodynamic characteristics in Bifurcated Coronary artery. The methodology involved the utilization of ANSYS SpaceClaim software for creating a geometric model of the bifurcated coronary artery. A mesh independent study was conducted to ensure the accuracy and reliability …
Published in Journal of Polymer & Composites · Vol. 11, Issue 13, 2023 · pp. 160–168 Read article
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A Narrative Review on an Insight of Herbal Origin Drugs and Their Traditional Medicine Formulations for the Treatment of Nephrolithiasis
Abstract: Ethnopharmacological relevance. There is no satisfactory treatment at present to cure or prevent kidney stone recurrences using predictable medicines. There are several marketed formulations in Ayurveda, Unani and Homeopathic Traditional Medicines (TM) have potential lithotriptic effects and clinical applications. In India, prevalence rates of complementary and alternative medicine (CAM) for the treatment of nephrolithiasis are being estimated at 63.9%. Aim of the review This review article intended to scientifically documented …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 1, 2024 · pp. 14–30 Read article
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Photochemical Insights into Light: Responsive Heterocyclic Compounds
Abstract: eterocyclic compounds are significant in a wide range of chemical fields. They are crucial components of the structural makeup of bioactive substances. Such compounds can be conveniently transformed through photochemical processes. Chemical reagents are rarely utilized. It is possible for members of one compound family to change into members of another. There is discussion of three key categories of photochemical rearrangements involving heterocyclic compounds: Photochemical reactions involving hydrogen atom transfer …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 1, Issue 2, 2023 · pp. 01–07 Read article
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Adaptation Strategies for Climate- Resistance Aquaculture: Insight from farmed fish
Abstract: As global climate change threatens food security, particularly regarding the vital protein source of fish, innovative strategies such as climate smart aquaculture emerge as critical solutions. This approach emphasizes the cultivation of climate-resilient fish species capable of thriving in changing environmental conditions. By integrating air-breathing species like the Pangasius catfish and the Giant Snakehead, aquaculture industries can bolster local economies while mitigating environmental risks. However, successful implementation requires careful consideration …
Published in International Journal of Marine Life · Vol. 1, Issue 1, 2024 · pp. 29–34 Read article
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Developing a Comprehensive Framework for User and Entity Behavior Analytics (UEBA): Integrating Advanced Machine Learning and Contextual Insights
Abstract: User and Entity Behavior Analytics (UEBA) has emerged as a crucial approach in modern cybersecurity for detecting and mitigating insider threats, compromised accounts, and other malicious activities within organizational networks. However, existing UEBA frameworks often face challenges in scalability, detection accuracy, and response effectiveness. This research work proposes a novel framework for UEBA that aims to address these limitations and enhance threat detection and response capabilities. The framework integrates advanced …
Published in Journal of Communication Engineering & Systems · Vol. 14, Issue 2, 2024 · pp. 20–32 Read article
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Designing Engaging Interactive Animatronics: Strategies and Implementation Insights
Abstract: The field of animatronics uses robotic systems to imitate realistic movements and activities in mechanical figures. To enhance the recognition and performance of the animatronic as a relationship mediator, it is important that the animatronics in recreational games be perceived as human companions to create productive interaction scenarios. This study describes the design and implementation of a Java- based programming method, an Adriano microcontroller, an open environment, a depth camera …
Published in International Journal of Optical Innovations & Research · Vol. 1, Issue 2, 2023 · pp. 27–33 Read article
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Exploring Diabetic Retinopathy from an Ayurvedic Lens: Insights Leveraging Bioinformatics
Abstract: Diabetic retinopathy is one among the target diseases for VISION 2025. The huge cost required for treatment, economic loss due to absenteeism from work etc... has made it as a great public challenge. Therefore it is in need of the hour to address the issues of diabetes mellitus with its complication Diabetic Retinopathy with all seriousness and it is quite essential to search for a affordable medical care for the …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 2, 2024 · pp. 45–51 Read article
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Unlocking The Bioactivity Potential: Molecular Insights and Predictions of Salen, Salophen, Allicin, Curcumin, and Piperine
Abstract: In this work, the prediction of the biological activity of several significant molecules, including salen, salophen, allicin, curcumin, and piperine, are discussed. Using Molinspiration software, the molecular properties of these compounds were calculated. These molecules are highly significant due to their extensive potential in medical applications. Salen and salophen, for instance, play crucial roles in cancer chemotherapy and act as inhibitors of angiogenesis. Curcumin is renowned for its antioxidant properties, …
Published in International Journal of Cheminformatics · Vol. 1, Issue 2, 2023 · pp. 14–21 Read article
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Targeting Dystrophin Restoration and Neuroprotection in Duchenne Muscular Dystrophy: Insights from Withania somnifera
Abstract: Duchenne muscular dystrophy is a genetic disorder. This disease affects men more common than women. Main objective of the present study was to identify the naturally active phytocompounds from Withania somnifera (Ashwagandha). Ashwagandha has a great value in the field of Ayurveda and Indian medicine and is used for treating muscular and neurological disorders. Toxicity prediction, molecular docking, statistical information, drug illness prediction, and Absorption, distribution, metabolism, excretion, and toxicity …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 64–84 Read article
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Recombinant Human EGF in Wound Healing: 3D Computational Insights
Abstract: A Growth Factor represents a naturally-occurring compound with the remarkable ability to incite cellular growth, proliferation, and differentiation. Typically manifesting as either a protein or a steroid hormone, these factors wield significant influence over an array of cellular activities. Their pivotal role lies in the regulation of diverse cellular processes, often serving as catalysts for cell specialization and maturation, a characteristic that distinguishes them from one another. For instance, bone …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 2, 2024 · pp. 6–10 Read article
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Mapping the Landscape of Neem Tree Research: Insights into Chemicals and Polymers through Bibliometric Exploration
Abstract: Azadirachta indica A. Juss, often referred to as Neem, is a rapidly developing tree that falls under the Meliacea family. For more than two millennia, Indians has relied on neem oil for its healing properties. Thus, to know the importance of neem tree, the study is needed. The Neem tree has been a subject of extensive research owing to its diverse array of chemicals and polymers with multifaceted applications. This …
Published in Journal of Polymer & Composites · Vol. 12, Issue 4, 2024 · pp. 144–154 Read article
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Boron Nitride Unleashed: Revolutionary Insights into Its Superhard Phases and Machining Aptitude
Abstract: Exploration from the prehistoric era has proven steel to be a hard substance. According to research, the four main crystalline forms of boron nitride are graphitic, cubic, rhombohedral, and wurtzitic. Better hard materials for industrial processes have been provided by diamond, hard ceramic, and cermet in the process of developing the front of the script, which is descriptive. Turning, cutting, drilling, boring, and grinding of hard materials have been linked …
Published in Journal of Catalyst & Catalysis · Vol. 11, Issue 2, 2024 · pp. 17–24 Read article
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The Role of Pyruvate Dehydrogenase in Non-Alcoholic Fatty Liver Disease: Therapeutic Insights and Future Directions
Abstract: Non-alcoholic fatty liver disorders (NAFLD) are defined by the accumulation of excess fat in the liver that has no other cause, such as drinking alcohol. Pyruvate dehydrogenase has been established as an alternative treatment for this disorder. NAFLD pathogenesis is complex and includes oxidative stress inflammatory processes and mitochondrial dysfunction. Impaired liver fatty acid oxidation and glucose oxidation are significant individuals in developing NAFLD, and strategies to reverse these defects …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 44–51 Read article
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Exploring Electric Skateboards: Comprehensive Insights into Design and Modeling
Abstract: Environmental protection and energy conservation have become primary concerns in the 21st century, prompting accelerated efforts to plan and develop electric vehicle (EV) technology. EVs offer numerous advantages, including zero emissions, the establishment of a new automobile industry, economic development, and the creation of efficient and smart transportation systems. This project introduces a foot-controlled steering system designed to enhance vehicle control, making it suitable for various road conditions and reducing …
Published in Trends in Electrical Engineering · Vol. 14, Issue 3, 2024 · pp. 39–45 Read article