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240 articles for “binding”
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Advanced Functional Polymers and Their Synergistic Role in Smart Composite Materials for Sustainable Industrial Applications
Abstract: Advanced functional polymers have revolutionized composite materials, offering enhanced properties such as self-healing, electrical conductivity, environmental adaptability, and high mechanical strength. These innovations are reshaping industries by enabling smarter, more efficient, and sustainable solutions. Functional polymers play a pivotal role in producing high-performance composite materials to meet the growing demands of sustainable industrial applications. Significant improvements in material properties mechanical strength, durability, thermal stability, and recyclability are achieved through the …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 12–27 Read article
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Hybrid Polymer Nanocomposites with Enhanced Dielectric and Optical Properties for Wireless Communication Systems
Abstract: The incorporation of nanofillers into polymer matrices offers a promising approach to enhancing the multifunctional properties of composite materials. This study examines the effect of nanofiller concentration on the dielectric performance, mechanical strength, thermal stability, optical absorbance, and electromagnetic interference (EMI) shielding effectiveness of polyvinylidene fluoride (PVDF)-based nanocomposites. Titanium dioxide (TiO₂) and zinc oxide (ZnO) nanofillers were incorporated at varying concentrations to assess their influence on material properties. EMI shielding …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 518–549 Read article
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Investigating The Alkalizing Potential of Chandanasava For Restoring Acid-Base Homeostasis in Renal Tubular Acidosis: A Computational and In Silico Pharmacological Study
Abstract: Chandanasava, a traditional Ayurvedic formulation, is recognized for its potential alkalizing properties, which may help restore acid-base homeostasis in conditions such as renal tubular acidosis (RTA). This study aims to investigate the active components of Chandanasava and their interactions with key renal target proteins, Pendrin and Carbonic Anhydrase II, which are essential for maintaining acid-base balance. An in silico approach was utilized to explore the pharmacological potential of the phytochemicals …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 28–52 Read article
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Photonic Polymer Composites for Light-Modulating Displays and High-Throughput Optical Data Transmission
Abstract: The combination of PMMA-based composites recently received substantial attention from the photonic applications field since these materials combine excellent optical transparency, mechanical flexibility and straightforward fabrication capabilities. The material performance of pure PMMA requires functional additives because it shows limited thermal properties and optical attenuation in addition to sensitivity against UV rays. The research explores developmental pathways for PMMA composites through combined use of nanoparticles and electro-optic polymers with dopants …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 838–860 Read article
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Investigation of the independent and combined roles of Gr and ZrO₂ on strengthening behaviour of Al-7075 Composites
Abstract: This study investigates the effect of individual and hybrid reinforcements on the mechanical and microstructural behaviour of Al7075 composite fabricated using the 2-step stir-casting technique. Four compositions were made with the base Al-7075, Al-7075 3 weight % ZrO2, and Al-7075 3 weight % Gr as well as a hybrid composite Al7075 with 3 wt.% Gr, 3 wt.% ZrO2. 2-step stir-casting was used to increase the wettability of the particles, decrease …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1060–1075 Read article
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Cyber-Secure IoT Framework for Monitoring Fiber-Reinforced Polymer Composites Using Embedded Sensors
Abstract: The present research paper suggests a cyber-safe Internet of Things system in real-time monitoring of fiber-reinforced polymer composites with inbuilt sensors. It is aimed at enhancing structural health maintenance, using sensual, intelligent analysis, and data protection in the same platform. Multi-layer architecture An embedded sensor, signal processing, anomaly detection and lightweight layer of cyber-security are developed. Experimental validation is done under controlled conditions and the performance is measured by these …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 434–458 Read article
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Design of Evaporator and Condenser for Solar Adsorption Refrigeration System
Abstract: Solar adsorption refrigeration systems provide a promising alternative for sustainable cooling in regions with limited grid access and high solar availability because they can convert low-grade thermal energy into refrigeration without mechanical compression. The performance of such systems depends strongly on the thermal behavior of the evaporator and condenser, since these components govern the refrigerant evaporation rate, condensation effectiveness, and overall cycle stability. This paper presents focus on the design …
Published in Journal of Refrigeration, Air conditioning, Heating and ventilation · Vol. 13, Issue 2, 2026 · pp. 1–10 Read article
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Structure and Origin Insight of Recent Coronavirus with Ongoing Therapeutic Approach
Abstract: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is highly transmissible zoonotic virus that was initially reported in late 2019 in Wuhan, China. Presently, it has infected approximately 1.5 million person and responsible for more than 0.1 million death across the world. It is likely evolved from bats and pangolin and genetically different from SARS-CoV-1, responsible for SARS disease. In present review, we have discussed the recent finding of its origin from …
Published in Research and Reviews : A Journal of Life Sciences Read article
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A Structure-based Design Approach to Catharanthus roseus Phytoconstituents as Potential Inhibitors of B-Cell Lymphoma 6 Protein
Abstract: Objectives: Lymphoma is a cancerous disease. It develops into millions of people worldwide. Identify the naturally active compounds from Catharanthus roseus, they have multiple values in the medicinal field of Siddha, and Indian Ayurveda are used as a disease-preventing agent. Drug illness prediction, toxicity prediction, statistical information, molecular docking, as well as absorption, distribution, metabolism, and excretion (ADME) analysis are used to predict the fit ligand as a drug. Methods: …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 14–34 Read article
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Anticancer Activity of Calotropis procera by Molecular Docking Analysis
Abstract: Cyclin-dependent kinase 2 (CDK2) is a protein synthesized by Calotropis procera. It is known to be responsible for causing cancer in the human body. Studies have presented the significance of the phytochemicals to inhibit the CDK2 protein. Adsorption, distribution, metabolism, and excretion (Swiss ADME) and PubChem were the pharmacological tools which were used to check molecular weight, which should be less than 500D, acceptors less than 10, and donors less …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 01–07 Read article
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Initiation of Distress in Asphalt Concrete After Practicing Moisture Damage
Abstract: The moisture damage of asphalt concrete is considered as major type of distress in heavy rainfall environment. In this work, the decline in the initial flexural stiffness of asphalt concrete was monitored after practicing the moisture damage process. The variations were analyzed relative to the control mixture. Asphalt concrete mixtures were created in the laboratory with the optimal binder content. Extra mixtures were also prepared with ±0.5% variation of binder …
Published in Trends in Transport Engineering and Applications · Vol. 11, Issue 2, 2024 · pp. 7–13 Read article
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In Silico Molecular Docking Studies of Phytocompounds from Melissa officinalis Against MPXV Poxin Target
Abstract: Objectives: This study aimed to evaluate the inhibitory potential of phytocompounds of Melissa officinalis against the MPXV poxin protein target, a key virulence factor in monkeypox infection. Methods: Molecular docking performed using PyRx, a virtual screening software, was conducted to predict the binding affinities of the compounds to MPXV poxin. Prior to docking, the compounds were subjected to comprehensive analysis, including Lipinski's rule of five, evaluation of physicochemical properties, pharmacological …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 2, 2024 · pp. 25–38 Read article
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Multi-Target Molecular Docking of Anantmul (Hemidesmus indicus) Compounds for Tay-Sachs Disease Treatment
Abstract: This research aimed to study the effects of the plant Anantmul (Hemidesmus indicus) in the treatment of Tay-Sachs disease using molecular docking studies. Tay-Sachs disease is a neurodegenerative autosomal recessive disorder caused due to accumulation of the molecule GM2 ganglioside which is caused due to lack of enzyme Beta Hexosaminidase which breaks down GM2 Ganglioside. Anantmul (Hemidesmus indicus) is a an ayurvedic plant used in the Indian subcontinent that has …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 2, 2024 · pp. 61–69 Read article
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Computational Investigation of Phytochemicals Targeting AKT1 for Major Depressive Disorder: A Molecular Docking and ADMET Study
Abstract: Major depressive disorder (MDD) is a prevalent neuropsychiatric condition affecting approximately 280 million individuals worldwide, with women exhibiting a 50% higher likelihood of diagnosis than men. Despite significant advancements in treatment, MDD remains a chronic and relapsing disorder, necessitating the exploration of novel therapeutic interventions. This study focuses on the AKT1 gene, a key player in neuropsychiatric disorders, and investigates its interactions with natural phytochemicals as potential alternatives to conventional …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 2, 2025 Read article
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Pharmacokinetic Profiling and Molecular Docking of Carvacrol and Structural Analogs: Targeting Quorum Sensing Proteins to Disrupt Biofilm-Mediated Antimicrobial Resistance in Multidrug-Resistant Bacterial Pathogen
Abstract: Antibiotic resistance, particularly in Pseudomonas aeruginosa, has become a major global health threat, exacerbated by the organism's ability to form biofilms and regulate virulence through quorum sensing (QS). The LuxR and LasR receptors are key regulators in this process, influencing both pathogenicity and antibiotic resistance. This study investigates potential QS inhibitors targeting these receptors as a strategy to mitigate antibiotic resistance. The primary objective was to identify novel ligands that …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 2, 2025 · pp. 43–61 Read article
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Hybrid Composite Behavior of Concrete-Filled Steel Tube (CFST) Columns: Review of Collapse Mechanisms and Polymer-Based Enhancements
Abstract: Concrete-Filled Steel Tube (CFST) columns are an advanced hybrid composite system where the steel tube's confinement and the concrete core's load capacity work together to improve structural performance. While commonly used in civil engineering, CFSTs can also be understood within the framework of composite materials, similar to polymer- and fiber-reinforced composites, in which interactions between phases determine strength, ductility, and failure modes. This review compiles experimental and numerical research on …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 78–97 Read article
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Evaluation of Mechanical Behaviour of Tungsten Carbide and Magnesium Reinforced Aluminium Matrix Composites
Abstract: With industries like automotive and aerospace also being more inclined on the lightweight material and strength that is much substantial, the aluminium-based metal matrix composite has become a major focus of interest. This paper examines the influence of addition of tungsten carbide (WC) and magnesium (Mg) particles on the mechanical characteristics of Al6063 aluminium alloy. The crucible casting technique was made in two composite compositions 2.5 percent and 5 percent …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 1–8 Read article
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Computational Molecular Docking Studies to Design Novel 2, 3-Substituted-1-(4-(Piperidin-1-yl) butyl)-1H- indol-5-ol Derivatives for Estrogen Receptor Alfa in AF-2 Domain
Abstract: The present manuscript describes the designing of novel 2, 3-Substituted-1-(4-(Piperidin-1-yl) butyl)- 1H-indol-5-ol derivatives as specific estrogen receptor alfa modulators and their screening by docking studies to determine the binding interaction for the best-fit conformations in the binding site of the ERα receptor. Based on the results of docking studies, the selected ligands reveal the all- important functional groups of the ligands that interact with active amino acid residues in the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 3, 2025 · pp. 15–49 Read article
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Molecular Docking Evaluation of Cedrus deodara Secondary Metabolites as a Potent Anti-ovarian Cancer Agent
Abstract: Objective: According to the statistics for the year 2022 it was seen that cancer total cases is 14,61,427. After breast cancer, ovarian cancer is the second most frequent cancer among women. The estrogen receptor (PDB ID: 1X7E), progesterone receptor (PDB ID: 1A28), and Phosphoinositide 3-kinases (PDB ID: 4FJY) can be considered as target protein for ovarian cancer. The plant Cedrus deodara and its phytochemicals were chosen in this study to …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 77–93 Read article
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An Integrated Study to Extrapolate the Interaction of NMDAR with Potential Ligands for the Treatment of Alzheimer’s Disease Symptoms
Abstract: Objective: Alzheimer’s disease (AD) is the most common neurodegenerative disease affecting the health status of older adults especially those above the age of 60 years. As an outcome, two types of medications have been developed for the treatment of its symptoms which are acetylcholinesterase (AChE) and N-methyl-D-aspartate receptor (NMDAR) antagonist. This paper uses the computational approach to understand the interaction of NMDAR with four major phytocompounds (curcumin, L-epicatechin, ginsenosides, and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 15–27 Read article