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47 articles for “albino rats”
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In vitro and in vivo Anti-Oxidant and Anti-Diabetic Evaluation of cladodes Crude Extract and Solvent fractions of Opuntia elatior mill (Cactaceae)
Abstract: Objective: Ariel part of Opuntia elatior (Cactaceae) has been used in folklare remedies to treat diabetes in America, Mexico and India. However, the anti-diabetic potential of cladodes of this medicinal plant is not scientifically validated and authenticated. The present study aimed to evaluate in vitro and in vivo anti-oxidant and anti-diabetic potential of methanol extracts and solvent fractions of O. elatior cladodes. Methods: Phytochemical analysis performed according to standard procedure. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 2, 2025 · pp. 77–88 Read article
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Combined Potential of Formulated diet (Pearl millet, Hungary rice, Moringa oleifera leaves and Cray fish) with Glibenclamide on Fasting blood glucose and lipid profile in alloxan induced diabetic wistar rats
Abstract: Background:The Interest to practice drug-food/nutrient interaction will not be overemphasis, however,the recognition of its importance to practice has been growing much slower. The aim of the study:Thisstudy aimed to identify combined effect of a formulated diet with glibenclamide on fasting bloodglucose and serum lipid profile in alloxan induced diabetic wister rats. Materials and methods: For thisinvestigation, 55 male albino wistar rats were randomly assigned to eleven groups of five. They …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 9, Issue 3, 2022 · pp. 12–26 Read article
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To Investigate Hormonal Fluctuations in Male Rattus norvegicus after Treatment with 50% Methanolic Extract of Acacia arabica
Abstract: The use of medicinal plants in traditional and modern medicine has garnered significant interest for their therapeutic potential. Acacia arabica, commonly known as babul, is renowned for its bioactive compounds and diverse pharmacological properties. This study investigates the hormonal fluctuations induced by 50% methanolic extract of Acacia arabica in male Rattus norvegicus, aiming to explore its potential as a male contraceptive. Male contraception remains limited primarily to condoms and vasectomy, …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 3, 2024 · pp. 28–38 Read article
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Safety of Ayurvedic Metal Origin Bhasma (Dhatu varga) through Acute Toxicity Studies: A Review
Abstract: Bhasma possess broad-spectrum therapeutic utility but are blamed due to frequently raising toxicity concerns. Although their safety has been evident with practice since ancient times, scientifically proven through toxicity studies, clinical safety, still comprehensive conclusive documentation is needed. Online published research articles on in vivo, oral single dose, acute toxicity studies on Bhasma of Dhatu Varga were searched through search engines and observations on behavioural, ponderal, autopsy, maximum tolerated dose …
Published in Research and Reviews: A Journal of Toxicology · Vol. 9, Issue 3, 2019 · pp. 43–50 Read article
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Evaluation for Diuretic Activity of Cassia auriculata
Abstract: The present study has been designed to elucidate the pharmacological activities like analgesic, anti-inflammatory and diuretic activities of flowers of Cassia auriculata on albino mice and rats. The doses for pharmacological activities was fixed petroleum ether, methanol and aqueous extracts was 500 mg/kg b.w. respectively. Analgesic activity was carried out by Eddy’s hot plate method. In this model, nociceptive reaction toward thermal stimuli in mice is a well validated model …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 8, Issue 2, 2018 · pp. 6–9 Read article
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In Vitro Evaluation of Analgesic Activity of the Methanol Extract of Pileamicrophylla (L.) Liebm. in Swiss Albino Mice
Abstract: Due to the availability of the plant Pileamicrophylla (L.) Liemb in Bangladesh, the present study was aim to investigatein vitroanalgesic activity of the methanol extract of Pileamicrophylla (L.) Liebm. analgesic activity was conducted at the doses of 200 and 400 mg/kg body weight usingSwiss albino mice as animal model by two thermal (hot plate and tail immersion test) methods. Overall, the extract showed significant analgesic activity compared to standard drug …
Published in Research and Reviews : Journal of Computational Biology · Vol. 6, Issue 3, 2017 · pp. 12–15 Read article
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In Vivo Hypoglycemic Activity of Aqueous Leaf and Root Extracts of Macaranga Barteri Müll. Arg. (Euphorbiaceae) In Swiss Albino Mice
Abstract: Background: Macaranga barteri Müll. Arg. is a perennial plant in the family Euphorbiaceae and is used in African traditional medicine for the management of several ailments, including diabetes. Although the leaves and stem bark have been studied for various pharmacological activities, little is known about the therapeutic value of the roots. Objective: This study evaluated the in vivo hypoglycemic activity of aqueous leaf and root extracts of M. barteri in …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 15, Issue 2, 2026 · pp. 60–78 Read article