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64 articles for “adverse reaction”
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Pharmacovigilance: The Silent Guardian of Patient Safety
Abstract: Pharmacovigilance is critical in protecting the populace health by monitoring, detecting and preventing adverse drug reaction (ADR) post drug approval. Although there is technological advancement and national initiatives such as the Pharmacovigilance Programme of India (PvPI), there is still a great problem of underreporting. Many benefits of effective pharmacovigilance include identification of risks early, better prescriptions and patient confidence. There are historical examples of drugs being withdrawn due to thalidomide, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 01–05 Read article
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Zebrafish in Drug Research: Decoding Biological Mechanisms and Finding Novel Therapeutic Targets
Abstract: The zebrafish, scientifically known as Danio rerio, is a powerful model organism in biological research because of its favorable traits, which include rapid development, genetic tractability, and transparent embryos. Zebrafish were first identified for their use in studies of vertebrate development, but they have since spread to a variety of disciplines, such as pharmacology, clinical research as a disease model, and most notably, drug development. Zebrafish have emerged as a …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 3, 2025 · pp. 1–8 Read article
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A Review of Telepharmacy: Advancements, Challenges, and Future Directions
Abstract: Like telemedicine, telepharmacy is a relatively new term that describes the delivery of pharmacological services. While tele comes from the Greek word “Telos,” which means from a distance, medicine comes from the Latin word “Meden,” which means to heal. The National Association of Boards of Pharmacy defines telepharmacy as the use of information and communication technology to provide patients with pharmaceutical treatment from a distance. Clinical pharmacy services are provided …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 34–42 Read article
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A Review on Transforming Patient Pathways: The Impact of Pharmaceutical Software on Drug Manufacturing and Safety Monitoring
Abstract: The development, production, and safety monitoring of pharmaceuticals are being revolutionized by incorporating digital technologies. Throughout drug lifecycles, pharmaceutical software which includes cloud-based systems, automation, data analytics, and artificial intelligence (AI) has emerged behind efficiency and innovation. Real-time monitoring, predictive maintenance, and process optimization are made possible in manufacturing by software tools like Digital Twins, Manufacturing Execution Systems (MES), and Quality Management Systems (QMS). These technologies improve batch consistency, lower …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 40–46 Read article
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Comprehensive Evaluation of Quercetin from Bauhinia purpurea for Its Anti-Acne and Anti-Inflammatory Potential, Including Advances in Quercetin-Loaded Nanogel Formulation
Abstract: Acne vulgaris is among the most prevalent chronic inflammatory dermatoses in clinical dermatology, afflicting a substantial proportion of the global adolescent and adult population. Conventional pharmacotherapies — including topical retinoids, benzoyl peroxide, and systemic antibiotics — remain the therapeutic mainstay; however, their long-term utility is progressively undermined by adverse cutaneous reactions, systemic toxicity, and the rising prevalence of antibiotic-resistant Cutibacterium acnes strains. These limitations have intensified scientific interest in plant-derived …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 2, 2026 · pp. 34–46 Read article
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Impact of Vaccine Awareness Campaigns on Pharmacovigilance Reporting and Public Safety Monitoring
Abstract: Vaccination programs have significantly contributed to the reduction of infectious diseases worldwide; however, their success is closely tied to public confidence and robust safety monitoring systems. Pharmacovigilance plays a critical role in identifying, assessing, and preventing adverse events following immunization (AEFI). In recent years, vaccine awareness campaigns have emerged as a pivotal strategy to improve public knowledge, reduce vaccine hesitancy, and enhance reporting of adverse drug reactions (ADRs). This review …
Published in International Journal of Vaccines · Vol. 3, Issue 2, 2026 · pp. 1–14 Read article
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Influence of Antibiotic Promotion Practices on Pharmacovigilance and Resistance Reporting Patterns
Abstract: The global escalation of antimicrobial resistance (AMR) has emerged as a critical public health crisis, undermining decades of therapeutic advancements. While inappropriate prescribing and misuse of antibiotics are widely acknowledged contributors, the role of pharmaceutical promotion practices remains underexplored in influencing prescribing behaviors and downstream pharmacovigilance systems. This review critically examines how antibiotic promotion strategies – ranging from direct physician engagement to digital marketing – affect adverse drug reaction (ADR) …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 · pp. 1–11 Read article
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Drug Marketing in Tropical Regions and Its Effect on Pharmacovigilance Awareness and Reporting
Abstract: Drug marketing practices in tropical regions present a complex interplay between pharmaceutical promotion, healthcare infrastructure limitations, and public health outcomes. These regions – characterized by high disease burden, socio-economic disparities, and diverse healthcare delivery systems – often experience unique challenges in ensuring safe and rational drug use. Aggressive and sometimes unregulated marketing strategies by pharmaceutical companies may significantly influence prescribing behavior, patient compliance, and, ultimately, pharmacovigilance systems. Pharmacovigilance, defined as …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 2, 2026 · pp. 1–17 Read article
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Evaluating the Role of Pharmacists in Managing Antibiotic Use and Combating Multi-Drug Resistance in Hospital Settings
Abstract: Antibiotic resistance is now one of the crucial health issues of the world, especially in hospitals where high usage of antimicrobials is increasing the rate at which multi-drug resistant (MDR) organisms appear. Misprescription, extended treatment, and over-use of broad spectrum antibiotics play a large role in the development of resistance resulting in the growth of morbidity, mortality and health care expenditure. This review analyses the essentiality of pharmacists in controlling …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 · pp. 12–19 Read article
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Pharmacodynamics and Drug–Receptor Interactions: Integrating PK/PD Modeling with Modern Drug Development
Abstract: Understanding drug action requires an integrated perspective of pharmacodynamics and pharmacokinetics, which together determine therapeutic efficacy and safety. This review provides a comprehensive overview of the mechanisms underlying drug action, with particular emphasis on drug–receptor interactions and their role in modulating physiological responses. Drugs exert their effects primarily through interactions with specific biological targets, including receptors, enzymes, ion channels, and transporters, resulting in a spectrum of desired and adverse outcomes. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 · pp. 33–47 Read article
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AI-Driven Pharmacogenomics and Precision Medicine: Future of Personalized Therapy
Abstract: Pharmacogenomics and artificial intelligence (AI) are emerging as important drivers of precision medicine, enabling healthcare systems to adopt individualized therapeutic approaches. Pharmacogenomics examines how genetic variations influence drug response, efficacy, metabolism, and toxicity, while AI provides advanced computational tools for analyzing complex genomic and clinical data. This review highlights the integration of AI-driven pharmacogenomics in personalized therapy and its potential to improve treatment outcomes. Machine learning, deep learning, natural language …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 2, 2026 · pp. 1–12 Read article
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THE BURDEN OF EMPIRICAL THERAPY: ANALYZING THE PREDOMINANCE OF BROAD-SPECTRUM ANTIBIOTIC USAGE IN LOWER RESPIRATORY TRACT INFECTIONS
Abstract: Lower respiratory tract infections (LRTIs) remain one of the leading causes of morbidity and hospitalization worldwide, particularly among older adults, immunocompromised individuals, and patients with chronic respiratory disorders. These infections include conditions such as community-acquired pneumonia, hospital-acquired pneumonia, bronchitis, and acute infective exacerbations of chronic lung disease, all of which often require rapid clinical intervention. Because microbiological confirmation of the causative pathogen frequently takes 48–72 hours, clinicians generally initiate empirical …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 Read article
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Integrative Therapeutics for Antimicrobial Resistance and Autoimmune Disease: Evidence and Pathways
Abstract: Background: Antimicrobial resistance (AMR) is accelerating globally, while autoimmune diseases and adverse drug reactions (ADRs) continue to rise. Ayurveda offers immunomodulatory, antimicrobial, and detoxification‑oriented interventions that may complement biomedical strategies. Objective: To propose a hypothesis‑driven integrative model combining Ayurvedic phytotherapy, panchakarma detoxification, and personalized dosha‑based care with evidence‑based medical management to mitigate AMR emergence, modulate autoimmunity, and reduce ADR incidence. Methods: A synthesis of mechanistic literature on Ayurvedic herbs with …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 2, 2026 · pp. 25–30 Read article
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A Study and Report on Impact of Clinical Pharmacy Services Over Indian Health Care System in the Management of Chronic Disorders/Diseases in Hospital
Abstract: The study aims to ensure safe, effective, economic, and patient friendly with the knowledge inputs of each professional practice. With the primary and secondary objectives being: to study the role of the clinical pharmacist/doctor of pharmacy professional in the management of chronic diseases/illness, minimise medication/prescription errors, minimise/prevent adverse drug reactions, all types of drug interactions, and unnecessary healthcare costs, reducing drug-related problems and to monitor drug therapy efficiently, attain desired …
Published in Research and Reviews: A Journal of Health Professions · Vol. 11, Issue 2, 2021 · pp. 46–82 Read article
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A Research Study and Report on Impact of Clinical Pharmacy on Vaccine Safety, Vaccine Vigilance, ADR Assesment and Reporting Among Pediatrics During Active Immunization Schedules at ESI Hospital
Abstract: Vaccine is a biological preparation that improves immunity to a given vaccine-preventable disease (VPD). A vaccine typically contains a disease-causing microorganism, or portion of it, and is often made from either live-attenuated or inactivated (killed) forms of the microbe, its toxin or one of its surface proteins. Vaccines may be monovalent or polyvalent (multivalent).. The main Aim of the study is to explore the knowledge, attitudes and concerns with respect …
Published in Research and Reviews : A Journal of Immunology · Vol. 11, Issue 2, 2021 · pp. 35–45 Read article
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Importance of AYUSH in Present Health Care Perspective
Abstract: The term AYUSH stands for Ayurveda, Yoga & Naturopathy, Unani, Siddha and Homeopathy systems of medicine. Within these medical systems, drug therapies play an important role in curing disease and maintaining health. These drugs comprise of natural molecules which are better absorbed and utilized in the human body and produce effect without adverse drug reaction in comparison to the synthetic molecules. Realizing the 21stcentury is termed as the “Century for …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 4, Issue 3, 2015 · pp. 5–8 Read article
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Comparison between Intravenous Injection of Iron Sucrose and Oral Administration of Iron for the Treatment of Iron Deficiency Anemia in Pregnancy
Abstract: The aim of this study was to compare the therapeutic benefits of intravenous iron and oral iron administration for the treatment of iron deficiency anemia (IDA) in pregnancy. A total of 50 patients with gestational age between 25 and 35 weeks with established IDA with Hemoglobin (Hb) 7–9 g/dl were randomized to receive either oral ferrous sulphate 200 mg twice daily or required dose of intravenous iron sucrose 200 mg …
Published in Research and Reviews : Journal of Surgery · Vol. 5, Issue 3, 2016 · pp. 25–28 Read article
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Artificial Intelligence -Driven in Clinical Pharmacy Practice: Transforming Medication Management and Patient-Centred Care
Abstract: Artificial intelligence (AI) is transforming clinical pharmacy practice by enhancing the safety, accuracy, and efficiency of medication management while supporting evidence-based clinical decision-making. Recent advances in machine learning, deep learning, natural language processing, and predictive analytics have enabled the integration of AI into various aspects of pharmacy practice, including drug discovery, pharmacovigilance, clinical decision support, personalized medicine, medication adherence, and patient counselling. The objective of this review is to provide …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 3, 2026 Read article
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Exploring Gesture Handling in The Shakti man Game: A User Experience Study
Abstract: Participants in "The Shaktiman Game" take on the role of the valiant hero Shaktiman in an engrossing 2D adventure. Players must fight their way through an endless barrage of enemies in this dynamic arena to get the best score. Player’s control Shaktiman's movements in the beginning by making natural hand gestures in front of a camera, which allows them to maneuver the character horizontally over an eye-catching gaming environment. The …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 1, Issue 2, 2023 · pp. 1–7 Read article
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Role of Protease in Virulence of Periodontal Bacteria
Abstract: Periodontitis is a polymicrobial, multifactorial disease with the most toxic protease that aids in emigration and the degradation of the host. Unattended bacterial contamination leads to periodontitis, and extreme gum problems may also bring about missing teeth and also bleeding. Major microorganisms associated with periodontitis are p.gingivalis, t. Forsythia, p.aeruginosa and t. Denticola. Virulence plays a major role in microbial contamination where different proteases released by microorganism aids in spreading …
Published in Research and Reviews: A Journal of Dentistry · Vol. 13, Issue 2, 2022 · pp. 9–15 Read article