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73 articles for “Synthetic treatment”
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Exploring the Role of MAPK3 in Major Depressive Disorder: Molecular Docking, Dynamics, and Binding Free Energy Analysis of Natural Compounds as Alternatives to Conventional Drugs
Abstract: Major Depressive Disorder (MDD) is a prevalent neuropsychiatric disorder with limited treatment efficacy and significant side effects associated with conventional antidepressants. Recent studies have highlighted the role of mitogen-activated protein kinase 3 (MAPK3) in the mechanisms underlying MDD, positioning it as a potential target for the development of novel therapeutic drugs. In this study, we employed various computational approaches to explore natural compounds as viable alternatives to synthetic antidepressants. Researchers …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 53–68 Read article
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Simulation and Optimization of Syngas Generation Process (GTL Stage I) using ASPEN Hysys
Abstract: The process of gas to liquid (GTL) conversion has been divided into three sections (section I: natural gas treatment and syngas production; section II: is Fischer Tropsch Synthesis sections (Main Reactors) and Stage III: Upgrading and treatment section).This work is mainly for Stage I. whereby Natural gas dehydration unit is simulated using Tri-ethylene Glycol to dehydrate the natural gas which includes (Free Water Knockout Drum (FWKD), Absorber and Distillation). Sweetening …
Published in Journal of Petroleum Engineering & Technology · Vol. 10, Issue 2, 2020 · pp. 48–67 Read article
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Comparative Analysis of Natural and Synthetic Fibre-Reinforced Composites: Mechanical Properties, Processing, and Sustainability Considerations
Abstract: The development of fibre-reinforced composites has significantly advanced engineering applications due to their excellent strength-to-weight ratio, corrosion resistance, and versatility. Synthetic fibres such as glass and carbon provide superior mechanical performance, but their production is energy-intensive and environmentally harmful. Natural fibres, including jute, flax, banana, and hemp, offer biodegradability, lower cost, and sustainability benefits, though they often fall short in strength and durability. Hybrid composites frequently demonstrate improved performance by …
Published in Journal of Materials & Metallurgical Engineering · Vol. 15, Issue 3, 2025 · pp. 77–95 Read article
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Review of Hydroxyapatite Coating: Enhances Bioactivity and Osteoconductivity in Natural Hard Tissues
Abstract: Hydroxyapatite (HA or HAP) of biologically (produced from coral, cattle, or marine algae) or synthetic origin is used to repair and regenerate bone in the form of granules, blocks, and scaffolds, either alone or in a composite with polymers or other ceramics, or as a coating on dental or orthopedics implants. From the perspective of enhancing bioactivity, numerous methods for surface alteration and its combinations have been suggested. The composite …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 9, Issue 2, 2022 · pp. 17–21 Read article
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Microsphere and Nanoparticle Drug Delivery Systems: Role of Polymers in Pharmacology
Abstract: Microsphere and nanoscale drug delivery methods have changed the field of pharmacology by making treatment agents more bioavailable, more targeted, and easier to manage. These delivery systems, which are mostly made up of polymers, look like a good way to get around the problems that traditional drug formulations have, like not dissolving well, clearing quickly, and spreading in different places. Plastics are very important in the creation of these improved …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 420–432 Read article
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A Review of Nanotechnology Application in Pharmaceutical and Health Care
Abstract: Nano drug and nano delivery systems are a fairly new but fleetly developing wisdom where accoutrements in the nanoscale range are employed to serve as means of individual tools or to deliver remedial agents to specific targeted spots in a controlled manner. Nanotechnology provides numerous advantages in treating chronic diseases by enabling precise, site-specific, and targeted drug delivery. Recently, there have been several remarkable applications of nanomedicine, including chemotherapeutic agents, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 07–17 Read article
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A Review on Tensile and Flexural Properties of Natural/Glass Fiber Reinforced Polymer Composites
Abstract: In the most recent decade, natural plant fibers like (jute, sisal, banana, hemp, kenaf, and so on) are getting consideration from numerous analysts and academicians to use it as a substitute support of engineered fiber strengthened polymer composites. Composite assume huge job as designing material and their utilization has been expanding step by step because of their particular properties, for example, high solidarity to weight proportions, high modulus to weight …
Published in Journal of Polymer & Composites · Vol. 8, Issue 3, 2020 · pp. 70–80 Read article
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An Effective & Novel Approach as Gastro-retentive Drug Delivery Systems
Abstract: Researcher’s curiosity about gastro-retentive drug delivery system increased so high in recent years because of its excellent drug releasing properties to the target site. The delivery system's residence time in the stomach can be extended with the usage of gastro-retentive drug delivery system by using a number of natural and synthetic polymers such as guar gum, hydoxy propyl methyl cellulose which can be used to improve the bioavailability of a …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 47–54 Read article
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Experimental Investigation of Water Absorption and Mechanical Behavior of Bamboo Fiber Based Polymer Composites
Abstract: The objective of this research is to assess the suitability of bamboo fibers as a sustainable alternative to synthetic and wood fibers for reinforcing polymer composites. Plant-based fibers, particularly bamboo, offer advantages such as biodegradability, lightweight nature, abundance, and impressive mechanical properties that rival or surpass those of conventional materials. In this study, special focus is placed on the extraction of long fibers from Dendrocalamus giganteus, using a combined mechanical …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1471–1481 Read article
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The Dual Crisis: Antibiotic Resistance and the Discovery Void – A Review of Novel Therapeutic Strategies and Non-Traditional Approaches
Abstract: The global rise of antimicrobial resistance (AMR) has emerged as one of the most critical public health challenges of the 21st century, threatening to undermine decades of therapeutic success and rendering conventional antibiotic regimens increasingly ineffective. Parallel to the escalating resistance rates is a profound “discovery void,” characterised by a steep decline in the development of new antibiotic classes since the late 20th century. Together, these two interconnected crises create …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 47–65 Read article
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Efficacy Evaluation of Trichoderma Harzianum, T. Viride, & T. Asperellum: Eco-Biocontrol Agents Against Dry Rot of Potato in Pakistan
Abstract: Fusarium sambucinum is one of the most aggressive fusarium species initiating potato dry rot disease around the world and causing significant economic losses. To alleviate reliance on synthetic fungicides as their long-term use may lead to fungal resistance, biocontrol assays against threatening fungal diseases hold significant importance as an eco-friendly management approach. Antagonists are gradually becoming hotspots and hold broad applicable prospects. Trichoderma harzianum, T. viride, and T. asperellumwere screened …
Published in International Journal of Fungi · Vol. 2, Issue 1, 2025 · pp. 46–50 Read article
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Advancing Gene Therapy: Next-Generation Viral Vector Engineering for Precision, Safety, and Scalability
Abstract: Gene therapy has emerged as a paradigm-shifting modality for the treatment of genetic disorders, malignancies, and rare diseases through the delivery of therapeutic nucleic acids aimed at correcting or modulating dysfunctional gene expression. Among the various delivery systems, viral vectors including adeno-associated viruses (AAVs), lentiviruses, adenoviruses, retroviruses, and herpes simplex viruses have proven indispensable owing to their high transduction efficiencies and adaptability. This review offers a comprehensive assessment of viral …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 37–55 Read article
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Anticancer, Bioactive, & Therapeutic Applications of Cannabinoids
Abstract: Cannabinoids, a complex class of lipophilic compounds found in Cannabis sativa L., are attracting significant clinical interest for their multifaceted therapeutic potential, particularly within oncology. This review provides a comprehensive synthesis of contemporary knowledge detailing the distinct anti-cancer properties of phytocannabinoids (such as δ-tetrahydrocannabinol and cannabidiol), endogenous endocannabinoids, and synthetic analogues. Accumulating evidence from robust in vitro and in vivo oncological models demonstrates that these compounds aggressively suppress tumor progression …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 2, 2026 · pp. 17–30 Read article
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Novel 1,3,4-Thiadiazole Derivatives: Design, Synthesis, Characterization and Anticancer Evaluation – A Review
Abstract: Cancer remains one of the leading causes of mortality worldwide despite significant advances in diagnosis and treatment. The clinical usefulness of many anticancer drugs is often restricted by toxicity, poor selectivity, and the emergence of drug resistance. These limitations have encouraged the search for novel heterocyclic compounds with improved therapeutic efficacy and safety. Among these, the 1,3,4-thiadiazole scaffold has gained considerable attention because of its favorable physicochemical characteristics, metabolic stability, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 · pp. 42–49 Read article
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Adsorption, Process Technology with Catalysis
Abstract: Surface of solids assumes a significant part in numerous physical and synthetic peculiarities. There are two principle purposes behind this exceptional job. First and foremost, the outer layer of a substance interfaces first with its environmental factors. Furthermore, the surface particles are in an alternate state as looked at to the atoms in the inside of the strong. The surface atoms interface all the more promptly with different substances which …
Published in Journal of Catalyst & Catalysis · Vol. 8, Issue 3, 2021 · pp. 7–14 Read article
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Crispr Cas – Revolutionizing Modern Therapies and Beyond
Abstract: CRISPR-Cas technology has emerged as a transformative tool in modern molecular biology, revolutionizing both fundamental research and clinical applications. This RNA-guided gene-editing system enables precise and efficient genomic modifications, offering unprecedented potential for addressing genetic disorders, infectious diseases, and oncological conditions through innovative therapeutic interventions. The inherent specificity and programmability of CRISPR-Cas systems have facilitated breakthroughs in diverse fields, including precision medicine, regenerative therapies, and immuno-oncology. Beyond its therapeutic applications, …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 25–38 Read article
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Polymer Chemistry in Biomedical Applications: Advances and Innovations
Abstract: Polymers have revolutionized biomedical sciences by playing a crucial role in medical devices, drug delivery systems, and tissue engineering. It is important to note that their unique combination of biocompatibility, mechanical strength, and chemical versatility makes them essential for applications such as implants, prosthetics, and diagnostic tools. Biomedical polymers are categorized into natural types (e.g., collagen, chitosan) and synthetic variants (e.g., polyethylene glycol, polylactic acid), each offering distinct benefits depending …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 Read article
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Sustainable Polymer Composites Reinforced with Natural Fibers: Processing, Properties, and Applications
Abstract: The environmental footprint of synthetic plastics has led to extensive studies of sustainable polymer composites reinforced with natural fibers like jute, sisal, hemp, flax, and coir. These biocomposites offer a greener solution to the conventional petroleum-based materials, which blends biodegradability and competitive mechanical characteristics. The present paper focuses on the processing methods, mechanical and thermal characteristics, and the possible application of natural fiber-reinforced polymer composites (NFRPCs). A survey of 50 …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1663–1670 Read article
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A Review on Heavy Metal Removal Techniques in Water Treatment
Abstract: The removal of heavy metal ions from wastewater is crucial for environmental safety and human health due to the toxic and persistent nature of these pollutants. This review comprehensively examines various water treatment methods, including adsorption, membrane filtration, chemical precipitation, electrochemical, and photocatalytic processes. Each technique is critically analyzed in terms of removal efficiency, operating conditions, and their respective advantages and limitations. Adsorption methods, particularly those using bioadsorbents, have gained …
Published in Journal of Water Pollution & Purification Research · Vol. 11, Issue 3, 2024 · pp. 15–28 Read article
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Synergistic Effects of Hybridized Nano-Silica and Hemp Fiber Reinforcement on Bio-Epoxy Composites
Abstract: Natural fiber-reinforced bio-epoxy composites have become promising sustainable alternatives to conventional synthetic-fiber petroleum-based materials, but are often limited by low fiber-matrix interfacial bonding, low thermal stability, and high moisture absorption which limit their application in structural applications. These issues are discussed in this work, by carrying out a systematic investigation of the synergistic effects of the hybridization of nano-silica particles with alkali-treated hemp fibers in a bio-epoxy matrix the composites …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 214–228 Read article