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395 articles for “Promising approach”
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Engineering Anti-Tau Monoclonal Antibodies for Alzheimer’s Disease and Parkinsonian Tauopathies: A Biotechnological Perspective
Abstract: Neurodegenerative disorders such as Alzheimer’s disease and Parkinson’s disease are characterized by progressive neuronal loss associated with abnormal protein aggregation. Among these, tauopathies are defined by the accumulation of hyperphosphorylated tau protein, which plays a central role in disease progression. Advances in biotechnology have enabled the development of anti-tau monoclonal antibodies (mAbs) as promising therapeutic agents aimed at neutralizing pathological tau species and inhibiting their propagation. This review provides a …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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The Dental Pulp: Vital Core of Tooth Functionality
Abstract: Dental pulp, an intricately specialized mesenchymal tissue, possesses limited regenerative capabilities attributable to the unique anatomical arrangement and the post-mitotic nature of odontoblastic cells. The process of complete pulp amputation, subsequent disinfection of the pulp space, and the insertion of synthetic materials results in the substantial loss of dentin, leading to enduring consequences such as a non-vital and structurally weakened tooth.Nevertheless, a beacon of hope emerges in the form of …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 1, 2024 Read article
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Unraveling Metagenomics: A Comprehensive Diagnostic Approach for COVID-19
Abstract: The COVID-19 pandemic has brought attention to the need for rapid, accurate, and scalable diagnostic techniques. Metagenomics, a powerful technique that enables the comprehensive analysis of genetic material from complex microbial communities, has emerged as a promising diagnostic approach for COVID-19. This article elucidates the principles of metagenomic sequencing, highlighting its ability to detect viral RNA directly from clinical samples without prior knowledge of the pathogen. Furthermore, we discuss the …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 2, 2024 · pp. 19–28 Read article
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An Integrative Review of Male Sexual Disorders and the Therapeutic Role of Unani Aphrodisiacs
Abstract: Sexual health is a vital component of overall well-being, encompassing physical, emotional, and psychosocial dimensions. Male sexual dysfunction – including conditions, like erectile dysfunction, premature ejaculation, and low libido – can significantly impact quality of life and intimate relationships. Aphrodisiacs, derived from the Greek goddess Aphrodite, are substances that stimulate sexual desire and performance. Historically, natural aphrodisiacs have been used in various cultures and include plant-based substances such as Yohimbine, …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 3, 2025 · pp. 8–15 Read article
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A Brief Review On Nanoparticles Drug Delivery System Used In Cervical Cancer
Abstract: Among cervical tumor-related deaths worldwide, cervical cancer is a major cause. The limitations of traditional methods, such as chemotherapy and radiation therapy, stem from their adverse effects and increased susceptibility to medications. Despite being seen as innovative options, immune checkpoint inhibitors (ICIs) have rather low clinical response rates. Reliable treatments for patients with metastatic or recurring cervical cancer are currently lacking. Lately, nanomaterials including polymers, liposomes, and dendrimers have been …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 1, 2025 · pp. 30–40 Read article
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Evaluating the behavior of Concrete after addition of stone dust to steel fiber reinforced concrete
Abstract: In contemporary construction practices, the utilization of concrete has become indispensable for various civil engineering projects worldwide. Concrete, augmented with both natural and artificial fibers, plays a crucial role in bearing compressive loads and efficiently transferring structural loads to the reinforcement and foundation. The current research delves into exploring the transformative effects of different mix designs, incorporating varying percentages of steel fibers, on the behavior of concrete. The study encompasses …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 12–19 Read article
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Rethinking Type-1 Diabetes Treatment: Emerging Medicines Based on AAT Therapy and C-peptide Preservation Therapy
Abstract: The increasing number of cases, especially in the younger age group, along with the lack of accessible clinical solutions, make Type-1 Diabetes (T1D) a growing global health concern. While gene therapy and transplantation approaches are promising avenues, their excessively high costs and logistical difficulties make them inaccessible to the majority and can impose a financial burden on those suffering from it, adding to the challenges already faced by these advanced …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 19–29 Read article
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Direct Synthetic Routes of MXenes and Their Application in Carbon Fiber Reinforced Plastics (CFRPs) As Supplementary Sizing Layer†
Abstract: Sized carbon fibers with a supplementary sizing layer of MXenes (synthesized via traditional MAX phases), bonded to carbon fibers (CFs) as well as the resin matrix via different kinds of physicochemical (van der Waals force, hydrogen bonding, covalent bonding) interactions enhanced the performance of the resulting carbon fiber reinforced plastic (CFRP) materials. This is because of the strong interface generated due to the appearance of MXene at the interface of …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 1, 2024 · pp. 07–13 Read article
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Exploring Potential Phytochemicals for Myasthenia Gravis Treatment: A Molecular Docking and ADME Analysis Approach
Abstract: Objective: Muscle feebleness and exhaustion derived from a disruption in neuromuscular transference are hallmarks of the crippling autoimmune disease myasthenia gravis (MG). The drawbacks of the current MG therapy options are frequently partial efficacy and adverse effects. To investigate the potential of phytochemicals in MG control, in this work we integrated molecular docking with ADME (absorption, distribution, metabolism, and excretion) analysis using a computer method. We identified molecules exhibiting favorable …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 1–13 Read article
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Big Data in Chemistry: Problems and Answers
Abstract: The rapid growth of experimental and computational chemistry data, researchers now have access to vast datasets, presenting both significant opportunities and challenges. This paper explores the primary challenges associated with managing, processing, and utilizing big data in chemistry, including data heterogeneity, integration across various scales and systems, lack of standardized formats, and the need for advanced tools for data analysis. Additionally, the paper discusses the ethical concerns of data ownership, …
Published in International Journal of Cheminformatics · Vol. 2, Issue 1, 2024 · pp. 9–14 Read article
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Handwritten Sanskrit Word Recognition: A Deep Learning Approach Using AlexNet
Abstract: Handwritten Sanskrit word recognition poses significant challenges due to the intricate structure of the script and the considerable variations in handwriting across individuals. To address these challenges, this research introduces a novel methodology employing transfer learning with the AlexNet convolutional neural network. The study utilized two distinct datasets: a specifically curated Sanskrit word image dataset containing 2616 samples, alongside a broader Devanagari character dataset used for validation purposes. The established …
Published in Current Trends in Signal Processing · Vol. 15, Issue 2, 2025 · pp. 33–43 Read article
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Next Generation Sequencing (NGS) in Personalized Medicine: Emphasizing Public Health Beyond Reality
Abstract: NGS is a modern technology that allows researchers to quickly sequence large amounts of DNA or RNA, it is also known as massively parallel sequencing or deep sequencing. NGS has revolutionized genomic research and biological sciences by its speed, scale, accuracy, ultra-high throughput, and cost. NGS replaced the conventional sequencing method. A novel idea in healthcare is precision medicine, which involves adjusting medical care to each patient’s unique traits and …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 1–17 Read article
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Advancing IoT Security through Blockchain-based Approaches
Abstract: The emergence of blockchain technology has revolutionized various industries, including the Internet of Things (IoT), by providing a decentralized and secure platform for data management and transaction processing. However, securing IoT devices and networks remains a significant challenge due to inherent vulnerabilities and the increasing sophistication of cyberattacks. Blockchain-based security approaches have shown promise in addressing these challenges, yet their adoption is hindered by a lack of comprehensive taxonomy and …
Published in Trends in Electrical Engineering · Vol. 15, Issue 1, 2025 · pp. 1–34 Read article
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Catalytic Degradation of Polymers Using Metal Oxides (Zno, Cuo): A Sustainable Approach
Abstract: The growing accumulation of synthetic polymeric waste, especially plastics, has become one of the most pressing environmental challenges due to their non-biodegradable nature and long-lasting presence in ecosystems. This issue is compounded by the widespread use of plastic materials in various industries, resulting in vast amounts of plastic waste that contribute to environmental pollution, clog waterways, and pose threats to wildlife. As global plastic production continues to rise, the need …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 1052–1062 Read article
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Microsphere-Based Drug Delivery: A Critical Review of Innovations and Applications
Abstract: Microspheres have emerged as a revolutionary approach in pharmaceutical sciences, offering controlled and targeted drug delivery with improved bioavailability, stability, and patient compliance. These spherical carriers, ranging from nanometers to micrometers in size, can encapsulate both hydrophilic and hydrophobic drugs, enabling sustained and site-specific release. The development of microspheres has been significantly driven by the need to enhance drug efficacy while minimizing systemic side effects. This review provides a comprehensive …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
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Digital Health Interventions in Cardiovascular Pharmacology: A Review
Abstract: Cardiovascular diseases (CVDs) represent a formidable global health challenge, demanding innovative strategies for timely detection, effective management, and continuous monitoring. This study delves into the transformative potential of digital health interventions (DHIs), such as telemedicine and remote monitoring, in reshaping cardiovascular care paradigms. DHIs offer unparalleled accessibility, convenience, and personalized attention, thereby promising to revolutionize traditional approaches to cardiovascular health management. One of the foremost advantages of DHIs lies in …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 1–5 Read article
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Machine Learning Approaches in Breast Cancer Diagnosis: Current Trends and Future Perspectives
Abstract: Since cancer is still one of the world's top causes of death, precise and effective detection techniques must be developed. Machine learning (ML) approaches have shown promise in recent years for enhancing cancer prognosis and detection. This paper presents a comprehensive review of the application of ML in cancer detection, focusing on various modalities including medical imaging, genomic data, and clinical records. We highlight the challenges associated with traditional cancer …
Published in International Journal of Radio Frequency Innovations · Vol. 2, Issue 1, 2024 · pp. 14–20 Read article
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Maintain Attendance Using Image Processing Technique
Abstract: Attendance tracking stands as a pivotal pillar in organizational management, bearing significant implications for operational efficiency, resource allocation, and fostering accountability. Traditional methodologies for attendance maintenance frequently exhibit deficiencies in terms of precision, security, and scalability, thus necessitating the exploration of avant-garde solutions. This research endeavors to introduce a pioneering approach to attendance upkeep, harnessing the prowess of image processing techniques synergized with artificial intelligence (AI) algorithms to surmount prevailing …
Published in Journal of Image Processing & Pattern Recognition Progress · Vol. 11, Issue 2, 2024 · pp. 29–34 Read article
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Antimicrobial Peptides and Bacteriophages as Next-Generation Alternatives to Conventional Antibiotics
Abstract: The growing threat of antibiotic-resistant bacteria has underscored the urgent need for innovative alternatives to conventional antibiotics. Antimicrobial peptides (AMPs) and bacteriophages are gaining recognition as next-generation therapeutics due to their distinct mechanisms of action and ability to target resistant pathogens effectively. AMPs, which can be natural or synthetic, disrupt microbial membranes and offer broad-spectrum antimicrobial activity with a reduced likelihood of resistance development. Bacteriophages, as bacteria-specific viruses, provide precise …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 9–27 Read article
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Thermodynamic Optimization and Exergy-Based Performance Analysis of Hybrid Thermal Management Systems for Electric Vehicles
Abstract: The transition toward sustainable transportation has brought electric vehicles (EVs) to the forefront of modern engineering innovation. Despite their environmental benefits and improved energy efficiency, EVs face major thermal challenges that affect performance, safety, and durability. Efficient thermal management of batteries, power electronics, and electric drive systems is vital to ensure reliability under diverse operating conditions. This study presents a detailed thermodynamic optimization and exergy-based performance analysis of hybrid thermal …
Published in International Journal of Energy and Thermal Applications · Vol. 3, Issue 2, 2025 · pp. 19–23 Read article