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66 articles for “Inherent”
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Advancing Gene Therapy: Next-Generation Viral Vector Engineering for Precision, Safety, and Scalability
Abstract: Gene therapy has emerged as a paradigm-shifting modality for the treatment of genetic disorders, malignancies, and rare diseases through the delivery of therapeutic nucleic acids aimed at correcting or modulating dysfunctional gene expression. Among the various delivery systems, viral vectors including adeno-associated viruses (AAVs), lentiviruses, adenoviruses, retroviruses, and herpes simplex viruses have proven indispensable owing to their high transduction efficiencies and adaptability. This review offers a comprehensive assessment of viral …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 37–55 Read article
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Evaluating the Performance of Test Cricket Players Using Principal Component Analysis and the Weighted Average Method
Abstract: This study evaluates cricket player performance using Principal Component Analysis (PCA) and a weighted average approach. In order to achieve this, we analyzed detailed batting and bowling datasets from the International Cricket Council (ICC) to calculate player performance based on various performance indicators. The datasets included comprehensive statistics from multiple matches and tournaments, allowing for an in-depth evaluation of players’ skills and contributions. PCA ranked players according to their participation …
Published in Recent Trends in Sports · Vol. 2, Issue 2, 2025 · pp. 20–30 Read article
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Analysis of Friction Stir Welding Utilizing ANSYS: A Study Based on Simulation
Abstract: Friction Stir Welding (FSW) represents a sophisticated solid-state welding methodology that has attracted considerable scholarly attention due to its efficacy in amalgamating high-strength, lightweight substrates including aluminium, magnesium, and titanium alloys. FSW enables the fabrication of defect free products with a substantial amount of mechanical and wear properties. The process is highly sensitive to various parameters that significantly influence the quality and strength of the final product. Studies have shown …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 3, Issue 2, 2025 · pp. 62–77 Read article
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Challenges of Upgrading Local Cattle with Exotic Breeds: Genetic, Environmental, Economic, and Sustainability Trade-offs
Abstract: The practice of upgrading local cattle with exotic breeds has gained popularity as a strategy to enhance milk and meat production. While this approach holds potential for improving productivity, it also presents a range of challenges that need careful consideration. This study examines the genetic, environmental, economic, and sustainability trade-offs associated with upgrading local cattle with exotic breeds. From a genetic perspective, upgrading can result in the dilution of traits …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
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Gene Therapy 2.0: Harnessing Cutting-Edge Technologies for Precision Medicine
Abstract: Somatic gene therapy has become the standard form of gene therapy; this creates the Gene Therapy 2.0 era. This new and distinct time consists in the new-generation genome-editing tools and markers, more efficient systems for gene delivery, and personalized medicine approaches that raise the efficacy and safety of the treatment. Base and prime editing are two types of CRISPR-based gene editing tools have provided high precision and reduced off-target effects …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article
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Enhancing LAN Security Using Machine Learning
Abstract: The modern Local Area Network (LAN) is a critical component of any organization's infrastructure, facilitating communication, resource sharing, and access to the wider internet. However, this connectivity also brings inherent security risks. Traditional security measures, relying on signature-based detection and rule-based systems, are increasingly struggling to keep pace with the evolving sophistication of cyberattacks. This is where Machine Learning (ML) offers a powerful alternative, enabling proactive threat detection and enhanced …
Published in International Journal of Wireless Security and Networks · Vol. 3, Issue 2, 2025 · pp. 07–16 Read article
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Securing the Internet of Things: A Survey on Lightweight Blockchain Framework for Enhancing Security and Privacy
Abstract: Modern technologies, supported by the Internet of Things (IoT), have imparted great speed in data sharing between connected devices across several domains of the economy. The Internet of things transformed data collection activities with its creation of smart homes and cities, healthcare, transportation environments, and industrial automation. The fact that there are multiple resource-limited devices, and continuous data transfer of sensitive information has turned the IoT devices less secure and …
Published in International Journal of Data Structure Studies · Vol. 3, Issue 2, 2025 · pp. 6–14 Read article
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Application of B-trees for Design of Optimal Page Replacement Technique in Modern Operating Systems
Abstract: Algorithms related to replacing the memory pages in operating systems are critical components of modern operating systems that manage virtual memory efficiently. Current algorithms such as LRU (Least Recently Used), Clock algorithms as well as FIFO (First-In-First-Out), often struggle with the increasing demands of contemporary applications and larger memory hierarchies. This research work proposes a novel approach utilizing B-tree data structures to design an optimal page replacement technique. The proposed …
Published in International Journal of Data Structure Studies · Vol. 3, Issue 2, 2025 · pp. 23–30 Read article
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The Next Era of Solid-State Innovation: Beyond Silicon
Abstract: The semiconductor industry is getting close to the physical and economic boundaries of silicon-based technology. A new era of solid-state innovation is beginning. Beyond Silicon: The Next Era of Solid-State Innovation looks at the materials, device layouts, and manufacturing methods that are about to change the way electronics and energy work. The article talks about improvements in wide- and ultra-wide-bandgap semiconductors, two- dimensional materials, and quantum and neuromorphic systems that …
Published in International Journal of Solid State Innovations & Research · Vol. 3, Issue 2, 2025 · pp. 19–23 Read article
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Impact of Partially Observable Markov Decision Process in Next Generation Satellite for Remote Sensing
Abstract: The integration of Partially Observable Markov Decision Processes (POMDPs) in next- generation satellite systems represents a transformative advancement in remote sensing technology. This article explores how POMDP frameworks address the inherent uncertainties and incomplete observability challenges in satellite operations, including dynamic task scheduling, resource allocation, and adaptive sensing strategies. By modeling satellite decision-making under uncertainty, POMDPs enable autonomous systems to optimize mission objectives while managing constraints such as limited power, …
Published in International Journal of Satellite Remote Sensing · Vol. 3, Issue 2, 2025 · pp. 20–28 Read article
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A Study of Optical Sensor in Clinical applications
Abstract: The escalating demand for precise, real-time, and minimally invasive diagnostic and monitoring tools in clinical practice has propelled the development of sophisticated sensor technologies. Among these, optical sensors have emerged as a cornerstone, leveraging the interaction of light with biological matter to translate molecular or cellular events into quantifiable signals. Their inherent advantages – including high sensitivity, specificity, rapid response times, non-ionizing nature, and potential for miniaturization – make them …
Published in International Journal of Optical Innovations & Research · Vol. 3, Issue 2, 2025 · pp. 1–7 Read article
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A Review of Torque Ripple Reduction Techniques in Switched Reluctance Motors
Abstract: Switched Reluctance Motors (SRMs) have emerged as a promising alternative to conventional motor technologies due to their rugged structure, low manufacturing cost, high-temperature capability, and suitability for harsh environments. Despite these advantages, the widespread adoption of SRMs in applications such as electric vehicles, household appliances, industrial drives, and aerospace systems is significantly restricted by the issue of torque ripple. Torque ripple manifests as periodic fluctuations in the developed electromagnetic torque, …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 3, Issue 2, 2025 · pp. 45–50 Read article
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Spintronic Logic Circuits for Ultrafast Processing
Abstract: Spintronic logic has emerged as one of the most promising post-CMOS paradigms capable of addressing the speed, density, and energy challenges of deeply scaled silicon technologies. By relying on the intrinsic properties of electron spin and magnetization dynamics, spintronic devices—particularly Magnetic Tunnel Junctions (MTJs), Spin-Transfer Torque (STT), and Spin–Orbit Torque (SOT) structures—enable ultrafast, non-volatile data processing with significantly reduced energy consumption. Despite remarkable device-level advancements, circuit- level realization of high-speed, …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 3, Issue 2, 2025 · pp. 35–43 Read article
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Hybrid Intelligence in Cyber Security: A Study
Abstract: The digital landscape is a battlefield of escalating complexity, where the volume, velocity, and sophistication of cyber threats have exponentially outpaced human-centric defense models. Traditional rule-based security systems and siloed artificial intelligence (AI) solutions, while valuable, are increasingly brittle, overwhelmed by zero-day exploits, polymorphic malware, and coordinated, state-sponsored campaigns that operate in the shadows of big data. This paper posits that the paradigm of cybersecurity must fundamentally shift from one …
Published in International Journal of Wireless Security and Networks · Vol. 4, Issue 1, 2026 · pp. 01–09 Read article
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Neuroinflammation Is Aggravated by the Aqueous Extract of Myrmecodia Platytyrea Tuber
Abstract: Myrmecodia platytyrea, commonly known as the ant plant, is a medicinal epiphyte traditionally used in Southeast Asia for its purported health benefits, including anti-inflammatory, antioxidant, antimicrobial, and anticancer activities. Its tuber contains abundant secondary metabolites, including flavonoids, tannins, phenolic compounds, and saponins. While these phytochemicals are generally associated with therapeutic effects, the biological activity of Myrmecodia extracts varies depending on the type of extract, dosage, and route of administration. In …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 · pp. 5–14 Read article
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The Mycobiome Frontier – Pre & Post 2020 Status: Integrating Fungal Bioactive Compounds, Probiotics, and Antimicrobial Peptides in Modern Therapeutics and Biotechnology.
Abstract: The fungal kingdom represents an indispensable resource in modern therapeutics and biotechnology, offering a diverse array of bioactive compounds, probiotics, and antimicrobial peptides (AMPs). Functional fungal polysaccharides (FFPs), such as beta-glucans, chitin, and mannans, are centrally involved in modulating the human gut microbiota, providing novel therapeutic avenues for chronic conditions including diabetes, neurodegenerative disorders, and cancer. These compounds act as prebiotics, nourishing beneficial bacteria and enhancing metabolic parameters such as …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 1–11 Read article
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LQR-Based Optimal Control of Inverted Pendulum System with State Estimation and Stability Analysis
Abstract: The inverted pendulum on a cart is a canonical benchmark problem in control systems engineering, capturing the essential challenges of stabilizing an inherently unstable, underactuated, and nonlinear plant. Classical Proportional-Integral-Derivative (PID) controllers, while widely employed in industrial practice, exhibit fundamental performance limitations when applied to such systems, primarily due to their inability to account for multivariable coupling, process noise, and the absence of a systematic optimization framework. This paper presents …
Published in International Journal of Advanced Control and System Engineering · Vol. 4, Issue 1, 2026 · pp. 31–43 Read article
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Pharmacoepigenomics of Replication Timing: How Anti- Cancer Drugs Reshape Chromatin Domains and Mutational Landscapes.
Abstract: DNA replication timing serves as a fundamental epigenetic feature that organizes genome function during the cell cycle (3), while anti-cancer drugs profoundly alter this process to disrupt tumor growth(4). These agents target chromatin architecture, shifting replication domains and reshaping mutational patterns critical for cancer evolution (1,5). DNA replication timing (RT) domains serve as dynamic epigenetic organizers, partitioning the genome into early- and late-replicating regions that correlate with chromatin states, gene …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Parallel Greedy Approach for Phylogenetic Tree Construction in the Context of Marine Species
Abstract: The rebuilding of phylogenetic trees for marine species shows major computing problems because of the massive genomic data and the huge biodiversity inherent in ocean ecosystems. Traditional phylogenetic methods are accurate but become more expensive when they are processing with thousands of marine taxa parallelly. This article shows a critical analysis of parallel greedy algorithms as an adaptable solution for large-scale marine phylogenetics. It examines the main principles of greedy …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 4, Issue 1, 2026 · pp. 33–45 Read article
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A study on Bridging Chemical Transformation and Climate Feedbacks in the Earth System
Abstract: The atmosphere operates as a vast and complex chemical reactor, where minute-scale transformations exert profound influence on planetary-scale climate stability. This research investigates the multi-scale coupling between reactive tropospheric chemistry and large-scale climate feedbacks, challenging traditional modeling approaches that often divorce chemical kinetics from dynamic processes. By integrating high-resolution chemical transport models (CTMs) with comprehensive Earth System Models (ESMs), we map the flow of energy and matter from the molecular …
Published in International Journal of Climate Conditions · Vol. 2, Issue 2, 2025 · pp. 1–8 Read article