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227 articles for “Genetics of the Disease”
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Review on Advanced Molecular Diagnostic Tools and Their Applications
Abstract: Although the diagnosis of diseases is still primarily based on conventional methods (staining, culture, biochemical analysis), a series of advanced molecular diagnostic tools are increasingly introduced and incorporated in the workflow of clinical laboratories worldwide. These tools, such as polymerase chain reaction, northern blotting, restriction length polymorphism, flow cytometry, southern blotting, fluorescent in situ hybridization, agarose gel electrophoresis and pyrosequencing that are based on either the properties of nucleic acids …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 3, Issue 3, 2013 · pp. 21–33 Read article
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Systematic Hydroponic Review and Cultivation Strategies for Bacopa Monnieri
Abstract: Bacopa monnieri (L.) Wettst. (Brahmi; Plantaginaceae) is a medicinally important herb whose nootropic, antioxidant and anti-inflammatory properties derive largely from a group of triterpenoid saponins known as bacosides. Rising global demand for such compounds has made reliable, high-yield production a research priority and has prompted a search for cultivation systems superior to conventional field cultivation. This review compares field cultivation, in vitro micropropagation, bioreactor culture, hydroponics and elicitation for their …
Published in International Journal of Trends in Horticulture · Vol. 3, Issue 2, 2026 · pp. 23–28 Read article
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Breeding for Biotic Stresses Resistance in Vegetable Crops: A Review
Abstract: AbstractVegetable pests and diseases have major effect on its production. Although application of fungicides and pesticides has helped control plant diseases and insect/pests, but indiscriminate use of hazardous chemical causes environment pollution, chemical residues in vegetables above threshold levels and emergence of new races/biotypes. Therefore at this junction, breeding for the development of biotic resistant cultivars is major objective of vegetable breeder’s. Basic research on the genetic bases of pest …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 4, Issue 1, 2015 · pp. 13–27 Read article
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From Ancient DNA to Modern Livestock: Paleogenomics
Abstract: Paleogenomics, an interdisciplinary blend of paleontology and genomics, has revolutionized our understanding of ancient DNA and its applications across various fields. In Animal Genetics and Breeding, this field has emerged as a pivotal tool providing invaluable insights into the historical genetics of domesticated animals. By reconstructing and analyzing the genomes of long-extinct organisms, paleogenomics sheds light on genetic diversity, evolutionary dynamics, and adaptations of ancient species. Paleogenomics significantly impacts animal …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 1–6 Read article
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Advances in Diagnostic Techniques in Veterinary Medicine
Abstract: Diagnostic techniques play a crucial role in veterinary medicine for accurate disease identification, treatment planning, and monitoring of animal health. This review article explores the latest advancements in diagnostic tools and technologies used in veterinary medicine, focusing on imaging modalities, molecular diagnostics, and point-of-care testing. The first section discusses the advancements in imaging modalities, including digital radiography, computed tomography (CT), magnetic resonance imaging (MRI), and ultrasonography. These technologies have revolutionized …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 12, Issue 1, 2023 · pp. 1–4 Read article
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Gene Drive Technology: Potential and Risks for Global Biodiversity
Abstract: Gene drive technology has emerged as a groundbreaking tool with significant potential to address critical global challenges, particularly in managing and preserving biodiversity. By enabling targeted alterations to the genetic makeup of species, gene drives could facilitate the control of invasive species, mitigate vector-borne diseases, and even aid in the restoration of endangered species. However, the rapid pace of development and deployment of gene drive technologies raises concerns about unintended …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 6–10 Read article
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Assessing the Growth and Development of Children with Celiac Disease (1–12 years): A Descriptive Study
Abstract: Introduction: Celiac disease is a chronic autoimmune disease. It affects genetically susceptible individual by making the small intestine permanently sensitive to gluten. Gluten is found in wheat, rye and barley. Celiac disease is caused by intake of gluten. Patient with celiac disease experiences diarrhea, steatorrhea, weight loss and failure to thrive due to malabsorption. Objective: To assess the growth and development of children with celiac disease (1–12 years) attending the …
Published in Research and Reviews : A Journal of Immunology · Vol. 9, Issue 3, 2019 · pp. 12–19 Read article
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Crispr Cas – Revolutionizing Modern Therapies and Beyond
Abstract: CRISPR-Cas technology has emerged as a transformative tool in modern molecular biology, revolutionizing both fundamental research and clinical applications. This RNA-guided gene-editing system enables precise and efficient genomic modifications, offering unprecedented potential for addressing genetic disorders, infectious diseases, and oncological conditions through innovative therapeutic interventions. The inherent specificity and programmability of CRISPR-Cas systems have facilitated breakthroughs in diverse fields, including precision medicine, regenerative therapies, and immuno-oncology. Beyond its therapeutic applications, …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 25–38 Read article
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Redefining Herd Health: No-Antibiotic Strategies for Revolutionizing Sustainable Dairy Development
Abstract: This study investigates the potential of no-antibiotic strategies to transform herd health management andpromote sustainable dairy development. Rising concerns over antimicrobial resistance (AMR) and the environmental consequences of antibiotic use have intensified the demand for alternative, sustainable disease management approaches. No-antibiotic strategies emphasize preventive health measures, biosecurity, and holistic practices, including optimized nutrition, vaccination, and natural antimicrobial alternatives. The study evaluates diverse management interventions, such as precision livestock farming, genetic …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 · pp. 12–34 Read article
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Hereditary Disease and Ethical Awareness in Students of Greater Noida, India
Abstract: Hereditary diseases are diseases that are transmitted from parents to offsprings. These diseases cause many deaths and sufferings in the world. Often majority of people in developing countries suffer because of illiteracy and ignorance, and are not able to take right decision when the problem persists in the family. Therefore, a survey has been designed and conducted on students of engineering and management branches between age group 18 and 25 …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 3, Issue 3, 2016 · pp. 25–29 Read article
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Magnetic ZnxFe2–xO3 Nanoparticles Enhanced Nanobiosensor Integrated with MOSFETs for Efficient Detections of Biomolecules and Cancerous Cells
Abstract: The human brain is mostly responsible for intelligence and consciousness. An artificial equivalence of this action is nanobiosensor, which is used in artificial intelligence. The need for nanodiagnostics platforms for detecting diseases at the genetic, molecular, and cellular level has triggered the development of nanobiosensors integrated with MOSFETs. This device enables simple, inexpensive rapid tests, accurate imaging methods, and accurate molecular diagnosis at point-of-care (POC). This device is seen as …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 14, Issue 3, 2024 · pp. 33–44 Read article
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FDA Drug Approvals 2024: A Comprehensive Review
Abstract: The year 2024 has been pivotal for the pharmaceutical industry, with the U.S. Food and Drug Administration (FDA) granting approval to a diverse array of new drugs. These approvals highlight significant strides in therapeutic innovation, targeting a spectrum of diseases from rare genetic disorders to prevalent chronic conditions. This article provides a detailed examination of the FDA-approved drugs of 2024, focusing on their therapeutic indications, mechanisms of action, and the …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 28–46 Read article
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Role of Ayurveda in Prevention of Congenital Disorder
Abstract: Introduction: Congenital disorder or birth defect is a condition existing at or before birth regardless of cause. Birth defects vary widely in cause and symptoms. About 20–30% of all infant deaths are due to genetic disorders. Birth defects may result due to genetic or environmental factors. This includes errors of morphogenesis, infection, epigenetic modifications on a parental germline or a chromosomal abnormality. The outcome of the disorder will depend on …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 10, Issue 3, 2021 · pp. 33–39 Read article
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Exploring the Complexities of Parkinson’s Disease
Abstract: Parkinson’s disease (PD) is a neurological disorder, primarily affecting older adults, marked by both motor and non-motor symptoms. This review explores PD as a multisystem disorder that influences the central, enteric, and autonomic nervous systems, along with the immune system and gastrointestinal tract. Key pathogenic features include the degeneration of dopamine-producing neurons in the substantia nigra and the formation of Lewy bodies containing misfolded α-synuclein proteins. The bradykinesia, tremors, stiffness, …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 3, 2024 · pp. 1–8 Read article
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Targeting Dystrophin Restoration and Neuroprotection in Duchenne Muscular Dystrophy: Insights from Withania somnifera
Abstract: Duchenne muscular dystrophy is a genetic disorder. This disease affects men more common than women. Main objective of the present study was to identify the naturally active phytocompounds from Withania somnifera (Ashwagandha). Ashwagandha has a great value in the field of Ayurveda and Indian medicine and is used for treating muscular and neurological disorders. Toxicity prediction, molecular docking, statistical information, drug illness prediction, and Absorption, distribution, metabolism, excretion, and toxicity …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 64–84 Read article
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Non -Invasive Ways to Detect Cancer
Abstract: Cancer is a diverse group of diseases characterized by uncontrolled cell growth and division, affecting millions worldwide and being a leading cause of death. The disease typically involves genetic alterations that disrupt the normal balance of cell growth, leading to the formation of tumors. Tumors can be benign, posing no threat as they do not spread, or malignant, capable of invading nearby tissues and metastasizing. There are more than 100 …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 2, 2024 · pp. 59–67 Read article
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A Review of Biotechnology Advancements as Key Drivers of Scientific Innovations
Abstract: The rising human challenges have necessitated the quest to find lasting solutions to improve living standards. Challenges in food security in terms of quality and quantity, medical and health issues, energy deficiency and limitations in areas of transportation, domestic and industrial needs, as well as environmental issues are some major areas of application of biotechnology to sustain human existence. This review examines major scientific innovations driven by biotechnology. Biotechnology applied …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 3, 2025 · pp. 22–33 Read article
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RNA- Based Drug Delivery, Current Advances, Pharmaceutical Applications, and Future Perspectives
Abstract: RNA-based therapeutics have emerged as a transformative approach in modern medicine due to their ability to regulate gene expression with high specificity and precision. Advances in molecular biology, RNA chemistry, and nanotechnology have accelerated the development of diverse RNA modalities, including messenger RNA (mRNA), small interfering RNA (siRNA), microRNA (miRNA), antisense oligonucleotides (ASOs), and RNA aptamers. These therapeutics offer promising strategies for the treatment of cancer, genetic disorders, infectious diseases, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 · pp. 27–41 Read article
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ALADIN and its Protein Interactions with the Nucleoproteins: An Insilico Analysis
Abstract: The nuclear pore complex (NPCs) are big, protein complexes made up of multiple units that traverse the nuclear envelope (NE), establishing a discerning channel between the cytoplasm and nucleus for the nucleocytoplasmic transport. It has different roles in cellular processes, like cell-cycle progression, control of gene expression, and signal transduction. NPC is a vast and complex structure, compiled from almost 30 proteins, termed nucleoporins. Earlier studies have shown that each …
Published in Research and Reviews : Journal of Computational Biology · Vol. 7, Issue 1, 2018 · pp. 28–31 Read article
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Ecophysiology of a Plant: A Review
Abstract: AbstractIn recent years, there has been sudden rise in the demand of herbal formulations and plant based drugs on global levels, resulting in heavy exploitation of medicinal plants. Uncontrolled and unscientific harvest of several species has created a major decline of species and habitat loss. To conserve these plant germplasm conservation and in vitro propagation is a safe method for producing genetically uniform and disease free plant. Keywords: medicinal plants, …
Published in Research & Reviews : Journal of Ecology · Vol. 4, Issue 2, 2015 · pp. 18–28 Read article