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319 articles for “Drug delivery systems”
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A Comprehensive Review on Buccal Drug Delivery System
Abstract: Buccal delivery involves the running of the desired drug through the buccal mucosal membrane lining of the oral cavity. The buccal region of the oral cavity is a striking target for administration of the drug of choice because it offers some discrete advantages over all other routes. However, the mucosal lining of the oral cavity drugs which undergo rigorous firstpass metabolism, for those drugs, buccal route are excellent. Buccal drug …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 8, Issue 2, 2017 · pp. 20–32 Read article
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A Novel Drug Delivery System - Microsphere
Abstract: Microspheres are the multi-particulate novel medication conveyance measurement structure, it contains the molecule size range from 1 to 50µ and typically round fit as a fiddle with free stream property. It generally known as "Microparticles". Microspheres are set up by covering the medication particles with the polymeric arrangement (which got in characteristic, semi-manufactured or engineered structure) to accomplish the controlled arrival of medication, which produce the drawn out activity with …
Published in Trends in Drug Delivery · Vol. 7, Issue 3, 2020 · pp. 27–33 Read article
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Advances in Nanoformulations for Targeted Drug Delivery Systems
Abstract: The work examines modern nanoformulations used for enhancing targeted drug delivery systems that simultaneously produce better therapeutic effects with reduced adverse effects. The pharmaceutical industry achieved deliverable drug development progress through diverse nanocarrier innovation which encompasses liposomes and nanoparticles and dendrimers and micelles. Tissue and cell-based directed delivery becomes possible via this technology to enhance the management of neurological disorders and cancer diseases. The investigation analyzes different nanoformulations by reviewing …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 01–07 Read article
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Concentration of Surfactant in Microemulsions as Novel Drug Delivery Systems
Abstract: Microemulsions are clear, stable, isotropic thermodynamically stable systems mixtures of oil, water and ,surfactant frequently in combination with a cosurfactant. Microemulsion system has acceptable potential to act as a drug delivery vehicle by putting a wide range of drug molecules. It has most effective advantage like excellent thermodynamic stability, high drug solubilization capacity, improved oral bioavailability and protection against enzymatic hydrolysis. Surfactant based chemical systems have been reported in many …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 2, 2020 · pp. 8–15 Read article
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Design and Development of Self Microemulsyfying Drug Delivery System of Olmesartan Medoxomil
Abstract: Olmesartan Medoxomil is poorly water soluble drug. It comes into the BCS II drug. Hence oral bioavailability of Olmesartan Medoxomil is less (26%). The purpose of this study is to develop novel dosage form of the self-microemulsifying drug delivery systems (SMEDDS) for the Olmesartan Medoxomil for enhancing its solubility hence the oral bioavailability. Before the formulation of SMEDDS, solubility study was performed in different excipients and select excipients on basis …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 3, Issue 3, 2013 · pp. 1–14 Read article
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Recent Update on Advanced Drug Delivery System
Abstract: Over the past decade, there has been a growing interest in the use of artificial intelligence (AI) technology for analysing and interpreting biological or genetic data, accelerating drug discovery, and identifying selective small-molecule modulators or rare molecules in addition to predicting their behaviour. The use of artificial neural networks (ANNs) for the rapid analysis of massive amounts of data, the development of novel hypotheses and treatment plans, the prediction of …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 1, 2023 · pp. 22–30 Read article
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Design and Development of Self Microemulsyfying Drug Delivery System of Olmesartan Medoxomil Smita D Patel*, M R Patel, K R Patel
Abstract: Olmesartan Medoxomil is poorly water soluble drug. It comes into the BCS II drug. Hence oral bioavailability of Olmesartan Medoxomil is less (26%). The purpose of this study is to develop novel dosage form of the self-microemulsifying drug delivery systems (SMEDDS) for the Olmesartan Medoxomil for enhancing its solubility hence the oral bioavailability. Before the formulation of SMEDDS, solubility study was performed in different excipients and select excipients on basis …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 3, Issue 3, 2013 · pp. 1–15 Read article
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A Novel Approach of Protein Peptide Drug Delivery System
Abstract: Protein and peptides perform vital functions in body and are essential for life. They show various roles as therapeutic agents in treatment of cancer and diabetes. Various routes are available for the delivery of proteins and peptides such as oral route, transdermal route, pulmonary route, parenteral route, ocular route, nasal route, buccal route. However physicochemical properties of protein and peptides make them challenging for exogenous administration, especially in oral administration. …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 7, Issue 2, 2020 · pp. 44–59 Read article
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Hydrogel as a Drug Delivery System
Abstract: Hydrogels are hydrophilic three-dimensional, polymeric networks system. Hydrogel are hydrophilic system and capable of absorbing large amounts of aqueous solvent. It behaves like a semisolid system and generally follow non-Newtonian property. Hydrogel provide easy application, good spreadibility, non-grease, non-staining properly etc. Moreover, hydrogels can be converted to variety of forms apart depending upon the requirement including Newtonian and non-Newtonian slabs, microparticles, nanoparticles, topical gel, films etc. Hydrogels are commonly used …
Published in Trends in Drug Delivery · Vol. 10, Issue 3, 2023 · pp. 33–39 Read article
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Child-Friendly Innovation: A New Era in Pediatric Drug Delivery Systems
Abstract: Pediatric formulations are becoming more and more popular as a result of advancements in pharmaceutical delivery technology. For young patients, there isn't a safe and effective drug delivery system in place. Since children's pharmacokinetics and pathophysiologic profiles differ from those of adults, it is imperative to design and develop an innovative and appropriate delivery system to provide accurate and dependable medicine administration to pediatric patients. Discussions will be held under …
Published in Trends in Drug Delivery · Vol. 13, Issue 2, 2026 · pp. 26–34 Read article
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Ocular Films as a Drug Delivery System Against Fungal Infections: Current Insights and Future Directions
Abstract: Fungal infections of the eye, including keratitis, endophthalmitis, and blepharitis, represent a challenging class of ocular diseases due to their potential for vision loss and the limited efficacy of existing treatments. These infections are caused by a range of pathogenic fungi, such as Aspergillus, Candida, and Fusarium species, and often require long-term therapeutic intervention. Conventional topical antifungal therapies, such as eye drops and ointments, suffer from poor ocular bioavailability due …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 101–109 Read article
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Drugs Design and Process Chemistry: A Factuality Study of Recent Advance in Drug Delivery Systems – A Comprehensive Review
Abstract: Recent years have seen significant advances in drug design and process chemistry, mostly due to breakthroughs in drug delivery technologies. This study provides a thorough examination of current developments in drug delivery, emphasizing strategies that improve therapeutic efficacy, reduce adverse effects, and maximize pharmacokinetic profile. The effects of several strategies on drug stability, solubility, and bioavailability are examined, including controlled-release systems, targeted delivery methods, and nanoparticle-based delivery. This review also …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 1, 2025 · pp. 26–35 Read article
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Nanoformulation Strategies: Emerging Innovations in Drug Delivery Systems
Abstract: Nanotechnology is significantly advancing the pharmaceutical industry by introducing nanosystems that improve drug delivery, therapeutic efficacy, and patient outcomes. Various nanosystems-such as liposomes, dendrimers, polymeric nanoparticles, solid lipid nanoparticles, carbon nanotubes, and metallic nanoparticles-offer benefits like enhanced bioavailability, targeted delivery, improved stability, and reduced side effects. Innovative formulation strategies, including surface functionalization, particle size optimization, and use of biodegradable carriers, support controlled and sustained drug release. Additionally, production in non-aqueous …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 54–67 Read article
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Buccal Drug Delivery System: A Review
Abstract: The occurrence of interfacial molecular attracting force into the surface of biologically known substrates and naturally or synthetically occurring polymer, that in turn permits the polymer to cling to the biologically known surfaces for a prolonged length of time, is known as bio adhesion. Bio adhesive polymerizing system has employed into creation of goods for a variety of biomedical applicability, including surgical glue and denture adhesive, for a long time. …
Published in Trends in Drug Delivery · Vol. 9, Issue 2, 2022 · pp. 16–27 Read article
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Microneedles: A Potential Drug Delivery System for the Treatment of Cancer
Abstract: Hypodermic needles, topical lotions, and transdermal patches are the most common methods for transdermal drug administration. Most medicinal drugs have a limited effect due to the stratum corneum layer of the skin, which acts as a barrier for molecules, allowing only a few molecules to reach the site of action. Microneedles are a novel type of delivery method that helps to improve medication administration through this route while also solving …
Published in Trends in Drug Delivery · Vol. 9, Issue 1, 2022 · pp. 39–61 Read article
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Pluronics®-Cyclodextrin Inclusion Complex for Targeted Drug Delivery System
Abstract: Host–Guest’ inclusion complexes have in Pluronics® and Cyclodextrins (CDs) have an enormous research attraction as drug vehicles. In addition, CDs in Pluronics® solutions has captured much attention for the researchers to develop supramolecular biomaterials by improving the solubility and stability of drugs in aqueous and gel medium by Pluronics®-CDs inclusion complexation. Keywords: Supramolecular, Pluronics®, Cyclodextrins (CDs), Inclusion complex
Published in Trends in Drug Delivery · Vol. 5, Issue 3, 2018 · pp. 1–4 Read article
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A Brief Review On Nanoparticles Drug Delivery System Used In Cervical Cancer
Abstract: Among cervical tumor-related deaths worldwide, cervical cancer is a major cause. The limitations of traditional methods, such as chemotherapy and radiation therapy, stem from their adverse effects and increased susceptibility to medications. Despite being seen as innovative options, immune checkpoint inhibitors (ICIs) have rather low clinical response rates. Reliable treatments for patients with metastatic or recurring cervical cancer are currently lacking. Lately, nanomaterials including polymers, liposomes, and dendrimers have been …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 1, 2025 · pp. 30–40 Read article
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Personalized Medicines in Pharmaceutics: Drug Delivery System
Abstract: Pharmaceutics personalized medicine is a developing area that seeks to customize medical interventions for specific patients. Instead of a one-size-fits-all approach, personalized medicine focuses on developing treatments that consider a person’s unique characteristics, such as their genetic makeup, environment, and lifestyle. This allows for more effective treatment outcomes, as drugs are specifically designed to work best for each patient, reducing side effects and improving therapeutic results. In pharmaceutics, this involves …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 11–22 Read article
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Computer Aided Drug Designing for Targeted Drug Delivery Systems
Abstract: The discovery and development of a contemporary sedate is widely acknowledged as an extremely difficult task that requires significant resources and effort. Therefore, computer-aided medication design techniques are widely utilized today to increase the productivity of the drug discovery and development process. Among structure-based and ligand-based drug design approaches, both recognized for their efficiency in drug discovery and development, various CADD (Computer-Aided Drug Design) techniques are evaluated based on specific …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 34–41 Read article
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Intrapocket Drug Delivery System: A Spatial Tool for Periodontitis
Abstract: Periodontitis is a disease attributable to multiple infectious agents. It results from extension of the inflammatory process initiated in the gingiva to the supporting periodontal tissues. Periodontal pockets provide natural reservoir bathed by gingival crevicular fluid that is easily accessible for the insertion of a delivery device. Intra-pocket, sustained release systems have emerged as a novel paradigm for the future research. Controlled release delivery of antimicrobials is a therapeutic intervention …
Published in Trends in Drug Delivery · Vol. 1, Issue 2, 2014 · pp. 24–29 Read article