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83 articles for “Blindness”
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The Analysis of Deep Learning-Based Methods for Identifying Diabetic Retinopathy
Abstract: Diabetic retinopathy (DR) is a degenerative eye condition resulting from diabetes mellitus, where high blood glucose levels lead to lesions on the retina. This condition is considered the leading cause of blindness among working-age diabetic patients, particularly in developing countries. As the disease is irreversible, the treatment aims to preserve the patient’s current vision. Early detection is crucial for effective management of DR to maintain vision. One of the main …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 · pp. 15–31 Read article
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Gene Therapy in Modern Medicine: Promises and Challenge in Treating Genetic Diseases
Abstract: Gene therapy is a medical approach that focuses on altering or adjusting an individual’s genes to treat or prevent illnesses. The aim is to repair faulty genes or insert new ones into the body to combat diseases. Gene therapy can involve directly introducing modified or new genes into a patient’s cells or altering the genes already present in the patient’s body. This approach shows potential for treating a range of …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 27–32 Read article
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Milk Allergy: Significance, Detection and Management
Abstract: Milk allergy is a significant public health issue, particularly among infants and young children, with prevalence rates between 2 and 6% in early childhood, declining to 0.1–0.5% in adulthood. It is an immune-mediated adverse reaction to milk proteins, primarily involving immunoglobulin E (IgE)-mediated responses. Symptoms range from gastrointestinal distress and respiratory complications to severe anaphylaxis. The etiology of milk allergy involves genetic predisposition, environmental factors, an immature immune system, and …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 14, Issue 1, 2025 · pp. 15–19 Read article
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A summary continuation analysis evaluating the prevalence and predictors of diabetic retinopathy in newly diagnosed type 2 diabetic patients.
Abstract: Context: Diabetic retinopathy (DR), the leading cause of acquired blindness in adults, affects approximately 93 million people globally. It is a serious complication of type 2 diabetes, resulting from prolonged damage to the blood vessels in the retina. Although largely preventable and treatable, DR continues to be the main cause of vision loss among working-age adults and significantly impacts quality of life. While most studies on DR in Nepal have …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 · pp. 21–30 Read article
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Digital Psychiatry: A Narrative Review on AI Positive Role in Mental Health
Abstract: Artificial Intelligence has rapidly evolved into a formidable instrument within the domain of mental healthcare, fundamentally altering the way we understand awareness, diagnosis, intervention and emotional regulation. This narrative review explores AI’s potential to foster positive mental health through tools such as natural language processing, machine learning, deep learning and computer vision. These technologies promise earlier detection of mental disorders, customized treatment plans and responsive emotional support. Yet, alongside these …
Published in Current Trends in Signal Processing · Vol. 15, Issue 3, 2025 · pp. 1–13 Read article
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A Review on Kaempferol Eye Drops for the Glaucoma Treatment
Abstract: One of the main causes of permanent blindness, glaucoma is defined by gradual damage to the optic nerve, mostly brought on by oxidative stress, neuroinflammation, and high intraocular pressure (IOP). The investigation of herbal alternatives is necessary since current synthetic therapies, such as beta-blockers and prostaglandin analogs, frequently result in ocular discomfort, systemic toxicity, and poor patient compliance. Clitoria ternatea contains kaempferol, a bioactive flavonoid that has shown anti-inflammatory, antioxidant, …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 110–121 Read article
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A Comprehensive Review of CNN-Based Framework for Multi-Sign Detection of Diabetic Retinopathy in Fundus Images Using Public Datasets
Abstract: Diabetic retinopathy (DR) is one of the main causes of vision impairment. Blindness prevention and effective treatment depend on early detection. A thorough deep learning-based framework for the automatic segmentation and simultaneous detection of exudates, hemorrhages, and microaneurysms – three important DR indicators – from retinal fundus images is presented in this work. These three pathological signs’ corresponding annotated image patches, along with background (no-sign) areas, were used to train …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 3, 2025 · pp. 14–23 Read article
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Enhancing Glaucoma Diagnosis with Deep Learning: A Study Using ResNet-50 and DenseNet-121
Abstract: Glaucoma is a leading cause of irreversible blindness worldwide, mainly resulting from progressive optic nerve damage, often related to elevated intraocular pressure. Early detection is essential to prevent vision loss, but traditional diagnostic methods rely on specialized equipment and trained professionals, making large-scale screening difficult. This study uses a publicly available fundus imaging dataset to explore the effectiveness of deep learning models for glaucoma detection. These datasets provide medical images, …
Published in International Journal of Brain Sciences · Vol. 2, Issue 2, 2025 · pp. 9–18 Read article
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Creating a ‘Sustainable Future’ through Secured-AI
Abstract: It is imperative in the present world that we need to figure out a way to move to a ‘Sustainable future’. However, a ‘Sustainable future’ from an energy standpoint can only be built by a ‘Sustainably intelligent’ society. But the individuals who come together to form a society tend to neglect any discussion around ‘Sustainability’ considering it as something to be driven in top-down manner. In reality, with the massive …
Published in Journal of Software Engineering Tools & Technology Trends · Vol. 12, Issue 3, 2025 Read article
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CRISPR-Cas9: Revolutionizing the Genetic Frontier
Abstract: The rapid development of CRISPR/CRISPR-associated enzyme (Cas) technology has enabled truly customised treatment of human genetic disorders, paving the way for recent developments in the field of gene therapy. Because CRISPR/Cas can accurately target and edit individual genes within a genome, it has established itself as a formidable tool for genetic manipulation. CRISPR/Cas9 technology allows for precise editing of specific DNA sequences in an organism's genome. This method uses three …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article
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Collaborative Care for Diabetic Retinopathy: Integrating Artificial Intelligence and Clinical Pharmacy Services - A Comprehensive Review
Abstract: Background: Diabetic retinopathy (DR) remains the leading cause of blindness among working-age adults globally, affecting approximately 103 million people worldwide. The integration of artificial intelligence (AI) technologies with clinical pharmacy services presents unprecedented opportunities to enhance screening, diagnosis, and management of DR through collaborative care models. Objective: This comprehensive review examines the current landscape of collaborative care approaches for diabetic retinopathy management, focusing on the integration of AI-powered diagnostic tools …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 118–128 Read article
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An Overview of Gene Therapy
Abstract: Gene therapy is a revolutionary technique in medical science that seeks to cure or stop illnesses by means of introducing, altering, or quieting genes inside a patient's cells. Advancements in molecular biology, genetics, and biotechnology have propelled this field forward markedly changed over the last few decades. The underlying idea of gene therapy is to introduce genetic material into target cells via viral or non-viral vectors to rectify faulty genes, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 89–105 Read article
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Comparison Of Postoperative Sore Throat Following Endotracheal Intubation With Or Without Water Based Lubricating Jelly
Abstract: Background: Water-soluble lubricant gel (X-Y jelly) was evaluated for its ability to lessen the common throat pain that follows tracheal intubation under general anesthesia. Materials and Methods: scheduled for elective surgery under general anesthesia requiring endotracheal intubation, Were enrolled in a prospective, randomized, double-blind comparative study. They were split evenly into two -member cohorts. One cohort received 3 mL of water-soluble X-Y gel smeared from the cuff tip to 15 …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 3, 2025 · pp. 1–7 Read article
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Creating a “Sustainable Future” Through Secure AI
Abstract: It is imperative in the present world that we figure out a way to move toward a sustainable future. However, a sustainable future from an energy standpoint can only be built by a sustainably intelligent society. Yet, individuals who come together to form a society tend to neglect discussions around sustainability, considering it something that should be driven in a top-down manner. In reality, with the rapid emergence of artificial …
Published in Journal of Software Engineering Tools & Technology Trends · Vol. 13, Issue 1, 2026 · pp. 1–7 Read article
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Swarm-Enabled AI for Smart Mobility and Sustainable Transport
Abstract: The significant issues facing the modern urban infrastructure are the management of road traffic problems, such as severe traffic congestion, the detection of unsafe driving behavior, and road safety. The traditional ground-based surveillance systems will be helpful, but they will reach their limits in large and dynamic environments. It is because of predetermined perspectives, blindness, and the inability to scale. To designate these problems, the present study proposes a traffic …
Published in Journal of Advancements in Robotics · Vol. 13, Issue 1, 2026 · pp. 33–38 Read article
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Caries-Preventive Effects of Self-Applied Subacidic 0.5% NaF-HF Gel via Toothbrushing in 7–8-Year-Old Schoolchildren: A Randomized Controlled Clinical Trial
Abstract: To assess the caries-preventive effectiveness of self-applied subacidic 0.5% sodium fluoride–hydrofluoric acid (NaF-HF) gel used during toothbrushing in children aged 7–8 years Objective: To assess the caries-preventive effectiveness of self-applied subacidic 0.5% sodium fluoride–hydrofluoric acid (NaF-HF) gel used during toothbrushing in children aged 7–8 years. Methods: This 1-year, multi-arm, double-blind, placebo-controlled, parallel-group randomized study evaluated the caries-preventive efficacy of self-applied 0.5% NaF-HF gel among primary schoolchildren. A total of 1200 …
Published in Research and Reviews: A Journal of Dentistry · Vol. 17, Issue 1, 2026 · pp. 14–19 Read article
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Preoperative Use of Midazolam vs Dexmedetomidine for Anxiolysis in Day-Care Surgery
Abstract: Surgical procedures trigger significant fear and anxiety that can adversely affect physiological responses and recovery outcomes. This prospective, randomized, double-blinded clinical trial compared the anxiolytic efficacy and safety of intravenous midazolam and dexmedetomidine in 60 patients undergoing day-care surgery. Primary outcomes included anxiety scores measured by STAI and sedation assessed by the OAAS scale at multiple perioperative time points. Secondary outcomes assessed in the study included detailed evaluation of hemodynamic …
Published in Research and Reviews: A Journal of Medicine · Vol. 16, Issue 1, 2026 · pp. 7–12 Read article
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Prospective Evaluation of the Optimal Concentration and Effect of Epinephrine as an Adjuvant to Local Anesthetics for Prolonging Block Duration and Reducing Systemic Toxicity in Outpatient Surgery
Abstract: Purpose: To evaluate the optimal concentration and effect of epinephrine as an adjuvant to local anesthetics for prolonging block duration and reducing systemic toxicity in outpatient surgery. Methods: The study involved a randomized double-blind clinical trial on 80 adult patients awaiting day-care extremity surgery. The patients were randomly assigned to two groups of equal size. One group, Group E, was given the local anesthetic agent along with epinephrine as an …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 1, 2026 · pp. 64–69 Read article
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An Overview on Microwave Remote Sensing for Earth Observation
Abstract: To understand the Earth from space, one must look beyond the visible eye. While optical satellites rely on the Sun’s reflection much like the human eye they are frequently blinded by the curtain of cloud cover, smoke, or the dark veil of night. To bypass these limitations, we turn to Microwave Satellite Sensing. By utilizing electromagnetic waves with wavelengths ranging from 1 millimeter to 1 meter, we can see through …
Published in Research & Reviews : Journal of Space Science & Technology · Vol. 15, Issue 1, 2026 · pp. 21–25 Read article
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IoT-Based Smart Stick for the Visually Impaired: Real-Time Obstacle Detection and Auditory Feedback System
Abstract: The smart stick is designed to assist visually impaired individuals by helping them detect obstacles in their surroundings without relying solely on physical contact. The device is equipped with sensors that continuously scan the path ahead of the user. When an obstacle is detected, the sensors convert the information into real-time audio signals that are delivered through headphones. These audio alerts allow users to understand their environment more clearly and …
Published in Journal of Communication Engineering & Systems · Vol. 16, Issue 1, 2026 · pp. 29–35 Read article