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1076 articles for “Ageing”
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Systolic-Predominant Hypertension and the Aging Heart: A Cross-Sectional Study on LVH and Cardiovascular Riskss
Abstract: Background: Systolic-predominant hypertension, defined as a systolic blood pressure ≥140 mm Hg with diastolic pressure <90 mm Hg, is the most prevalent form of hypertension in the elderly. It arises primarily due to age-related arterial stiffening and baroreceptor dysfunction. Once considered a benign outcome of aging, systolic-predominant hypertension is now recognized as a major risk factor for cardiovascular morbidity and mortality. Aim and Objective: To evaluate the cardiac status and …
Published in Research and Reviews: A Journal of Medicine · Vol. 16, Issue 1, 2026 · pp. 13–24 Read article
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Nature’s Pharmacy: Plant-Based Antifungal Agents and Their Therapeutic Potential
Abstract: Antifungal resistance has increased dramatically over the last 10 years, causing serious problems for healthcare because of higher morbidity and death. The urgent need for new treatments is highlighted by the scarcity of effective antifungal medications, their toxicity, and the rise of resistant strains. Since many plants have bioactive secondary metabolites with strong antifungal qualities, including alkaloids, flavonoids, terpenoids, phenolics, and saponins, ethnobotanical sources offer a viable path. Plants with …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 1–7 Read article
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Speech Therapy in the Digital Age: Telepractice and Remote Interventions
Abstract: In the digital age, advancements in technology have revolutionized various aspects of healthcare, including speech therapy. This study explores the emergence and evolution of telepractice and remote interventions in speech therapy. Telepractice, interchangeably labelled as teletherapy or telehealth, denotes providing speech therapy services remotely using telecommunication technology. Its incorporation into speech therapy has broadened service accessibility, notably benefiting underserved or remote locales. Moreover, it has ensured uninterrupted care delivery during …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 1, 2024 · pp. 42–46 Read article
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Progeria Syndrome Unveiled: A Scientific Odyssey into Premature Aging Mechanisms and Therapeutic Frontiers
Abstract: Progeria, or Hutchinson-Gilford Progeria Syndrome (HGPS), is a rare and fatal genetic disorder in childhood, exhibiting features akin to premature aging. Despite normal appearances in infancy, affected children face accelerated aging with distinct facial characteristics, including micrognathia, dental malformations, lower body weight, early hair loss, decreased joint mobility, lipodystrophy, etc. The cause of HGPS is a point mutation that occurs at the exon 11 of the LMNA gene which normally …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 2, 2024 · pp. 52–68 Read article
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Weaning Age Shaping Puberty in Heifer: Insights from Nutritional, Physiological, Hormonal and Environmental Perspectives
Abstract: The onset of puberty in dairy heifers is a critical determinant of their reproductive performance and overall productivity. This study reviews the influence of weaning age on the timing and quality of puberty, synthesizing insights from nutritional, physiological, hormonal, and environmental perspectives. Early or late weaning can significantly impact heifer development, influencing body weight, fat deposition, and metabolic health. Nutrition plays a vital role in shaping growth rates and reproductive …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 14, Issue 1, 2025 · pp. 19–31 Read article
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Synthesis, Molecular Docking and Biological Evaluation of Novel Chlorobenzenesulfonamide Analogues of Ibuprofen as Anti-Bacterial, Anti-Diabetic and Anti-Alzheimer Agents
Abstract: In this work, we have synthesized novel chlorobenzensulfonamide tertiary amide based analogues of Ibuprofen (Ibu) and investigated them for their anti-bacterial, anti-diabetic and anti-Alzheimer activities. In the first step, Ibu was converted to amide derivatives by incorporating different aromatic amines. These were further converted into sulfonamide analogues (Sul-Ibu, 1-9) by treating it with p-chlorobenzensulfonyl chloride. Sul-Ibu (1-9) were screened against S. aureus, B. subtilis, S. mutans, E. coli, P. aeruginosa, …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 41–55 Read article
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Cervical Leiomyomas: Age associated insights from 3 Year prospective study from Tertiary Care Hospital
Abstract: Cervical leiomyomas are rare benign smooth muscle tumours of cervix, often presenting diagnostic challenges due to their uncommon occurrence and overlapping features with other cervical pathologies. This is a 3-year prospective study involving a total of 460 female subjects who were diagnosed with various gynecologic complications, with a particular focus on cervical leiomyomas. The study aims to provide a comprehensive age-wise distribution of cervical leiomyomas, emphasizing the incidence and prevalence …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 Read article
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Drug Repurposing of Anticancer Agents JP-8g and REDX05358 Against the Target Protein Plectin 1a in Epidemolysis Bullosa Simplex with Muscular Dystrophy (EBS-MD)
Abstract: Epidermolysis Bullosa Simplex with Muscle Dystrophy is a genetic disease affecting the skin and muscles which can be seen at birth or start at adulthood due to the mutation in the protein Plectin 1a (PLEC gene) causing skin blisters and muscle weakness. This protein is seen in sarcolemma, Z disks in skeletal muscles, hemidesmosomes in skin and cardiac muscles giving stability to cytoskeleton, playing a crucial role in neuromuscular transmission …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 22–34 Read article
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Synthesis, Molecular Docking and Biological Evaluation of Novel Chlorobenzenesulfonamide Analogues of Ibuprofen as Anti-Bacterial, Anti-Diabetic and Anti-Alzheimer Agents
Abstract: In this work, we have synthesized novel chlorobenzensulfonamide tertiary amide based analogues of Ibuprofen (Ibu) and investigated them for their anti-bacterial, anti-diabetic and anti-Alzheimer activities. In the first step, Ibu was converted to amide derivatives by incorporating different aromatic amines. These were further converted into sulfonamide analogues (Sul-Ibu, 1-9) by treating it with p-chlorobenzensulfonyl chloride. Sul-Ibu (1-9) were screened against S. aureus, B. subtilis, S. mutans, E. coli, P. aeruginosa, …
Published in International Journal of AgroChemistry · Vol. 3, Issue 1, 2025 · pp. 35–49 Read article
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Designing Intelligent Agents for Effective Collaboration with Human in Complex Environment
Abstract: An intelligent agent is a self-governing system that can take action to accomplish its goals based on how it perceives its surroundings. This paper introduces a newly designed humanoid robot that demonstrates significant advancements in performance, reliability, durability, energy efficiency, and environmental sustainability. The design emphasizes a bio-inspired musculoskeletal system, enabling natural and flexible motion while improving operational lifespan. A self-repair system is integrated to allow the robot to address …
Published in Journal of Control & Instrumentation · Vol. 16, Issue 3, 2025 · pp. 1–7 Read article
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Assessment of Knowledge, Attitudes and Practice of Family Planning among Women of Reproductive Age in Northern Nigeria: A Sociological Study
Abstract: Family planning is a very vital element of reproductive health that enables individuals and couples to decide on how many and how far they would have their children. It is important in enhancing maternal health, child health, alleviating poverty and enhancing sustainable development. Although family planning services are available in Nigeria, their use has been low in most regions in the country especially Northern Nigeria. The paper evaluated the KAP …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 1, 2026 · pp. 45–64 Read article
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Computational Exploration of Bhrijraj-derived Phytochemicals as Potential Anti-inflammatory Agents: A Molecular Docking Study with Cyclooxygenase-II Complex
Abstract: The molecular docking analysis was meticulously conducted using state-of-the-art computational tools, notably Chimera and Python. These tools were employed to unravel the complex interactions between the identified phytochemicals from Bhrijraj and the target protein, COX-II. The 3D structures of the phytochemicals were prepared with precision using ChemSketch, ensuring accuracy in the subsequent molecular docking simulations. This rigorous approach enhances the reliability and validity of the findings. This research aims to …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 31–37 Read article
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Effectiveness of A structured teaching program on Leucorrhoea and it's management for women of Reproductive age group at selected college in Honavar
Abstract: Leucorrhea, also known as leucorrhea, is a white, yellow, or green discharge from a woman's vagina, which may be normal or asign of an infection. Leucorrhea is common during pregnancy and is typically normal if the discharge is thin, white, and odorless.Physiological leucorrhea is a condition that occurs in young women several months to a year after the onset of menstruation. It sometimes occurs in newborn girls and usually lasts …
Published in International Journal of Women's Health Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 40–44 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Co-Delivery of Multiple Therapeutic Agents
Abstract: The co-delivery of multiple drugs using advanced nanocarriers has revolutionized targeted therapy in various diseases, particularly in cancer, infectious diseases, and neurological disorders. Multi-layered polymeric nanocarriers (MLPNs) offer a sophisticated platform to encapsulate multiple therapeutic agents with precise control over drug release, bioavailability, and synergistic effects. These nanocarriers are designed with distinct polymer layers that enable sequential or simultaneous drug release based on stimuli-responsive mechanisms such as pH, temperature, and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 406–419 Read article
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Synthesis, characterization, and antibacterial activity of silver nanoparticles with expired minocycline as reducing agent: proposed as a recycling technique
Abstract: In this research, expired minocycline, a broad-spectrum tetracycline antibiotic, was employed as both a reducing and stabilizing agent for the eco-friendly synthesis of silver nanoparticles. This sustainable method avoids the use of toxic chemical reducing agents, providing a greener alternative for nanoparticle production. The synthesized silver nanoparticles were analyzed using several characterization techniques, such as UV-Vis’s spectroscopy, scanning electron microscopy, transmission electron microscopy, and Edex analysis, to assess their structural, …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 16, Issue 1, 2026 · pp. 30–43 Read article
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Neuro-Symbolic Agentic AI for Autonomous Scientific Discovery: Integrating Deep Reinforcement Learning, Quantum Simulation, and XAI-Audited LLM Hypothesis Generation in Drug Target Identification
Abstract: The exponential growth of multi-omics data and the increasing complexity of disease-associated protein interactomes have rendered conventional drug target identification pipelines computationally and epistemologically inadequate. This paper presents the Neuro-Symbolic Agentic AI for Scientific Discovery (NS-AASD) framework, a unified architecture that cohesively integrates deep reinforcement learning (DRL) exploration strategies, variational quantum simulation (VQS) of protein conformational dynamics, and XAI-audited large language model (LLM) hypothesis generation within an autonomous scientific discovery …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 2, 2026 Read article
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A Study to Assess the Effectiveness of Home-based Stretching Exercises on Joint Pain Among Clients with Osteoarthritis in Selected Old Age Home, Rajkot City, Gujarat
Abstract: Osteoarthritis (OA) is a commonly encountered condition in middle-aged and older individuals, marked by its slow development. Strengthening exercises targeting the quadriceps muscles, situated in the front thigh, can mitigate knee pain, and reduce disability associated with OA. The musculoskeletal system encompasses the bones of the skeleton, the joints where these bones connect, and the muscles responsible for enabling and regulating movement. The knee, the largest and most complex joint, …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 24–28 Read article
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The Effectiveness of a Nurse-led Cervical Cancer Prevention Program Among Reproductive-age Women in Selected Areas of Chennai
Abstract: Background: Cervical cancer remains a major global health issue, significantly impacting women's health. Early detection and preventive measures through screening, along with enhanced awareness, are vital in lowering mortality rates associated with this disease. This study aimed to evaluate the effectiveness of a nurse-led cervical cancer prevention program in improving knowledge and practice related to cervical cancer prevention among women. Methods: This quasi-experimental study was conducted with 60 women divided …
Published in International Journal of Oncological Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 6–13 Read article
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Diglycidyl Ether of Bisphenol A (DGEBA) Based Epoxy Sizing Agent Induces Surface Polarity in Carbon Fibers†
Abstract: Determination of the chemical structure and composition of the sizing agent is a challenge as its concentration is low, varying in the range from ~0.5 wt.% (for polyacrylonitrile, PAN, based carbon fibers) to ~1 wt.% (for pitch-based carbon fibers). Moreover, such a piece of knowledge is vital for designing compatible polymer matrices to prepare CFRPs for diverse applications. As a result, the sizing layer that is coated on the carbon …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 2, 2024 · pp. 24–34 Read article
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Evaluation of Chemical Constituents of Terminalia Arjuna Bark: As a Cardio-Protective Agent
Abstract: In the past, the primary source of medicinal agents was herbal remedies. One such medicinal plant that is well known for its many therapeutic benefits, particularly its cardiovascular effects, is Terminalia arjuna (TA). The therapeutic effects of these substances are due to a wide range of natural chemical compounds, such as flavonoids, polyphenols, triterpenoids, tannins, glycosides, minerals, proteins, and others. These compounds work together to provide the health benefits associated …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 1–6 Read article