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856 articles for “Medical use”
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Gene Therapy 2.0: Harnessing Cutting-Edge Technologies for Precision Medicine
Abstract: Somatic gene therapy has become the standard form of gene therapy; this creates the Gene Therapy 2.0 era. This new and distinct time consists in the new-generation genome-editing tools and markers, more efficient systems for gene delivery, and personalized medicine approaches that raise the efficacy and safety of the treatment. Base and prime editing are two types of CRISPR-based gene editing tools have provided high precision and reduced off-target effects …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article
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Ayurvedic Management of Vataja Oshtharoga Whole System Research (W.S.R.) to Pigmented Contact Cheilitis—A Case Report
Abstract: Acharya Sushruta, in his ancient text, delineated 65 types of Mukha Roga, categorizing them into seven Mukha Avayava. Among which eight Oshtha Roga was classified as Vattaja, Pittaja, Kaphaja, Sannipataja, Rakta, Mamsaja, Medaja, and Kshataja. Among these, Vataja Oshtha Roga stands out, typified by pigmented contact cheilitis in modern medical parlance. This condition manifests initially with a tingling, itching sensation accompanied by swelling of the lips. Over time, the lips …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2024 · pp. 09–13 Read article
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Computational Investigation of Withania somnifera Compounds Targeting S. pombe SMN YG-Dimer in Spinal Muscular Atrophy: Insights from Molecular Docking Analysis
Abstract: Objectives: The primary objective of this study is to determine the potential of phytochemical constituents of Withania somnifera in treating spinal muscular atrophy, an autosomal recessive genetic neurodegenerative disorder, through computational techniques. To investigate the binding affinity of phytocompound to the target protein S. pombe SMN YG-Dimer through molecular docking. Besides, evaluating the pharmacological attributes of phytochemical constituents to assess their ability as an ideal prospect for developing therapeutic medication. …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 2, 2024 · pp. 39–52 Read article
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Deep Learning Applications in Bone Fracture Detection for Improved Radiographic Diagnostics
Abstract: Bone fracture detection is a critical aspect of medical diagnostics, traditionally relying on manual interpretation of radiographic images by experienced radiologists. This discipline has undergone a revolution with the introduction of machine learning (ML), which can improve accuracy, shorten diagnosis times, and lessen human error. This study investigates the use of different machine learning methods to enhance and automate the identification of bone fractures in radiography pictures. We utilized a …
Published in International Journal of Optical Innovations & Research · Vol. 2, Issue 2, 2024 · pp. 17–22 Read article
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A Study and Prediction of Psychological Disorders Through Machine Learning
Abstract: Physical illness is very much visible but not psychological illness therefore, it requires more attention and care. Psychological disorders also known as psychiatric disorders refer to a wide range of conditions affecting a person’s thought process, leading to significant changes in the behavior of an individual. The most prevalent psychological disorders include depression, anxiety disorders, and post-traumatic stress disorder (PTSD). Symptoms of psychological disorders vary greatly but include common symptoms …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 2, Issue 2, 2024 · pp. 32–38 Read article
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Challenges and Opportunities in the African Pharmaceutical Industry
Abstract: Background: The pharmaceutical industry in Africa has significant potential for growth; however, it is overwhelmed with grappling challenges. Nonetheless, these challenges can create a window of opportunities for innovation. This article provides an in-depth analysis of the profound challenges and opportunities in the continents pharmaceutical industry. Methods: Using data collected from published literature, reports and gray literature was used to conduct a narrative review. Using data collected from various publications …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 3, 2024 · pp. 88–98 Read article
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CRISPR-Cas9: Revolutionizing the Genetic Frontier
Abstract: The rapid development of CRISPR/CRISPR-associated enzyme (Cas) technology has enabled truly customised treatment of human genetic disorders, paving the way for recent developments in the field of gene therapy. Because CRISPR/Cas can accurately target and edit individual genes within a genome, it has established itself as a formidable tool for genetic manipulation. CRISPR/Cas9 technology allows for precise editing of specific DNA sequences in an organism's genome. This method uses three …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article
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Advancements in Buccal Patch Drug Delivery Systems: A Comprehensive Review of Evaluation Parameters
Abstract: The most dependable delivery method is buccal patches because it offers many improvements over alternative methods.This delivery method circumvents the hepatic first pass metabolism to deliver the medication into the systemic circulation. Buccal patches are inserted between the cheek and gums, where they dissolve and absorb through the buccal cavity's mucosal membrane. Polymers can be used to control the drug's delivery, and intelligent polymeric systems are a good option for …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 15, Issue 2, 2025 Read article
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CNN-Based Wound Segmentation: A Review of Models and Performance Evaluation
Abstract: Deep learning, particularly convolutional neural networks (CNNs), has altered medical image processing by automating and precisely segmenting complex medical pictures. Wound segmentation, a critical application in automated wound assessment, is essential for wound size estimation, classification, and healing progress monitoring. This study presents a comprehensive review of CNN-based wound segmentation models, focusing on their architectures, methodologies, and performance on diverse datasets. Four deep learning models, including two U-Net variants (5-layer …
Published in Current Trends in Signal Processing · Vol. 15, Issue 1, 2025 · pp. 33–46 Read article
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Pharmacological evaluation of Hepatoprotective activity of Indian medicinal plants Cordia Myxa and Canscora diffusa on wistar albino rats
Abstract: Two plants (Cordia myxa and Canscora diffusa), which were claimed to possess hepatoprotective activity, were selected. The Selected plants were authenticated by an expert botanist. In the current study, herbal extraction involving solvents of decreasing polarity (petroleum ether, ethyl acetate, and hydroalcoholic) was used to extract bioactive compounds from the plants of Cordia Myxa and Canscora diffusa in polyherbal preparations. A phytochemical evaluation was performed, including an acute toxicity study …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 31–44 Read article
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Integrating Ayurveda in Infertility Management: A Case Study on Fimbrial Blockage
Abstract: Infertility significantly impacts a woman’s psychological and physical health, as well as that of her family. Fallopian tube blockage is one of the leading causes of female infertility, accounting for a substantial number of cases globally. Conventional medical approaches, including in vitro fertilization (IVF) and surgical procedures, often present barriers due to their high cost, invasive nature, and limited accessibility. Additionally, cultural, financial, and personal considerations can further restrict their …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 3, 2025 · pp. 12–19 Read article
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The Heat of Competition: Assessing Climate Vulnerabilities and Adaptive Governance in Endurance, Winter, and Youth Sports
Abstract: Background: Climate change is fundamentally reshaping the environmental parameters of global sport, posing unprecedented risks to athlete health, safety, and performance. As rising temperatures, frequent extreme heat events, and deteriorating air quality become the new normal, athletic environments from community fields to elite international arenas face an existential threat. Purpose: This study provides an interdisciplinary synthesis of the multifaceted impacts of climate change on athletes, integrating evidence from sports medicine, …
Published in International Journal of Climate Conditions · Vol. 2, Issue 2, 2025 · pp. 9–17 Read article
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Needles of Wellness: Exploring the Transformative Benefits of Acupuncture
Abstract: Acupuncture, rooted in traditional Chinese medicine, has expanded beyond treating physical pain to playing a significant role in mental wellness. The term “Needles of Wellness” captures its dual benefits in pain relief and emotional health. While effective for conditions, like osteoarthritis and migraines, recent studies show its growing use in managing anxiety, depression, insomnia, and PTSD. Stimulating specific body points modulates the autonomic nervous system, reducing cortisol and enhancing endorphin …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 2, 2025 · pp. 1–9 Read article
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Review on Machine Learning Techniques for Heart Failure Analysis in Health Industries
Abstract: There are few bodily components as crucial as the heart. It aids in the filtration and distribution of blood to every area of a body. The world's biggest cause of death is heart disease. It has been reported that symptoms include breathing difficulties, fast heartbeat, and chest discomfort. They analyze this data on a regular basis. This review begins with a brief introduction of cardiac disease and the present methods …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 29–43 Read article
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Impact of a Structured Educational Program on Awareness of the Janani Shishu Suraksha Yojana (JSSY) Among Expectant Mothers in a Designated Primary Health Center in Bengaluru
Abstract: The Janani Shishu Suraksha Karyakram (JSSK) was launched to offer comprehensive support services including cost-free delivery, transportation, medications, diagnostic services, blood, and nutrition to expectant mothers and ill infants up to a year old at public healthcare facilities. This research utilized a quantitative methodology, adopting a pre-experimental design with a single group evaluated before and after the intervention. Information was gathered using a systematically designed questionnaire. RESEARCH DESIGN: This study …
Published in Journal of Nursing Science & Practice · Vol. 14, Issue 1, 2024 · pp. 45–50 Read article
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Integrating Human-Centric Principles into Machine Design: Ergonomic and Safety Enhancements in Mechanical Systems
Abstract: The integration of human-centric design (HCD) principles into mechanical systems has become increasingly critical in contemporary machine design. As machines become more complex and operate within high-interaction environments, the need for design strategies that prioritize human safety, usability, and comfort has intensified. This review explores how ergonomic insights, safety standards, and user experience (UX) considerations influence the physical configuration, control mechanisms, and operational safety of mechanical systems across industrial, healthcare, …
Published in Trends in Machine design · Vol. 12, Issue 2, 2025 · pp. 33–37 Read article
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Computational Approaches to Understanding Cellular Signaling Pathways
Abstract: Cellular signaling pathways are fundamental in regulating vital processes, such as cell growth, differentiation, and apoptosis. The intricate and interconnected nature of these signaling networks requires sophisticated methods for their analysis. Computational approaches, including mathematical modeling, network analysis, and machine learning, have revolutionized the way researchers analyze and simulate cellular signaling. This article provides a comprehensive overview of computational strategies employed to model signaling pathways, with a focus on integrating …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 8–13 Read article
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Nanotechnology in BattleField: A Study
Abstract: Nanotechnology, a rapidly evolving frontier of science and engineering, has revolutionized multiple sectors, including medicine, electronics, and materials science. Its application in military domains presents both intriguing opportunities and complex challenges. The abstract titled "Nanotechnology in Battlefield: A Study" offers a comprehensive overview of how nanotechnology is transforming warfare and military strategy. The abstract emphasizes the ethical and moral implications of deploying nanotechnology in warfare. The potential for creating weapons …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 14, Issue 2, 2024 · pp. 18–29 Read article
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Assessment of Diuretic Activity of Hydroalcoholic Extract of Matricaria Chamomilla (Linn.) and Its Phytochemical Analysis with Emphasis on Toxicology
Abstract: While the traditional medicines are derived from medicinal plants, minerals and organic matter, the herbal drugs are prepared from medicinal plants only. This current research work will be very beneficial in figuring out the Matricaria chamomilla leaves extract diuretic effect by determining the ions and electrolyte excreted by the animals using ion selective channel inhibition. The phytochemical screening results revealed that the after which it was observed whether the alkaloids …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 1–10 Read article
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Microsphere and Nanoparticle Drug Delivery Systems: Role of Polymers in Pharmacology
Abstract: Microsphere and nanoscale drug delivery methods have changed the field of pharmacology by making treatment agents more bioavailable, more targeted, and easier to manage. These delivery systems, which are mostly made up of polymers, look like a good way to get around the problems that traditional drug formulations have, like not dissolving well, clearing quickly, and spreading in different places. Plastics are very important in the creation of these improved …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 420–432 Read article