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595 articles for “comprehensive approach”
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Melanoma Skin Cancer Detection Using Deep Learning
Abstract: Cancer as one of the major diseases rank in the World is still very challenging to diagnose and treat hence need for the technological advancements. Chemotherapy, radiation, as well as surgery therapies have several drawbacks including non-selective action, damage to healthy tissues, and multi-drug resistance. Smart nano-theranostics, an advanced integration of nanotechnology with diagnostic and therapeutic modalities, offers a next-generation approach for precision oncology. Thus, the development of multifunctional nanoparticles …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 2, 2025 Read article
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Kisunla (Donanemab): A Novel Breakthrough Illuminating a Path to Better Alzheimer’s Outcomes
Abstract: Background: Alzheimer’s disease (AD) is a progressive neurodegenerative condition marked by cognitive decline, memory loss, and loss of independence. Despite decades of extensive research, disease-modifying treatments have been limited in success. Recent therapeutic advancements have led to the development of monoclonal antibodies targeting amyloid-beta (Aβ) plaques, particularly the pyroglutamate-modified variant, a key pathological hallmark of AD. Objectives: This review aims to explore the therapeutic potential of Donanemab (Kisunla), a novel …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 3, 2025 · pp. 37–45 Read article
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Comprehensive Review on Antimicrobial based Hydrogel for Wound Healing
Abstract: Chronic wounds present a significant clinical challenge due to their prolonged healing time, high risk of infection, and frequent recurrence. The development of novel wound dressings with both healing and antimicrobial properties is essential for effective wound management. This study focuses on the formulation and evaluation of an antimicrobial drug-loaded hydrogel designed to promote chronic wound healing. Chronic wounds are a growing concern in healthcare, often taking weeks or even …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 72–88 Read article
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Effectiveness of structured teaching programme on knowledge regarding Prophylactic vaccination against cervical cancer among adolescent girls
Abstract: Background: Adolescent health encompasses the variety of methods used to prevent, identify, or treat the health and wellness of young people. Adolescent health also includes the sexual and reproductive health of children and young adults. Women of all ages are susceptible to HPV infection. The human papillomavirus is the cause of cervical cancer . The HPV vaccine is an important main preventive measure against cervical cancer . Thus, it is …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 Read article
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Crystal Defects and Their Characterization in Modern Materials Science
Abstract: The physical and chemical properties of crystalline solids are fundamentally dictated by deviations from structural perfection, known as crystal defects. From the point-scale vacancies that drive diffusion to the planar boundaries that determine mechanical strength, defects serve as the primary "tuning knobs" in material design. This review provides a comprehensive examination of point, line, and planar defects, exploring their formation energetics and their role in plastic deformation via crystallographic slip. …
Published in International Journal of Crystalline Materials · Vol. 3, Issue 1, 2026 · pp. 15–19 Read article
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Significance of Nanoparticles in Phase Change Materials as Heat Transfer Fluid for Solar Heat Absorption
Abstract: The utilization of solar energy as a sustainable and eco-friendly power source has gained significant traction in recent years, with innovations constantly evolving to improve efficiency and effectiveness.one such innovation lies in the integration of nanoparticles into phase change materials (PCMs) to enhance their heat transfer capabilities, making them ideal candidates for solar heat absorption applications. This paper delves into the significance of nanoparticles in PCMs as heat transfer fluids …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 57–65 Read article
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Spintronic Logic Device Modeling and Energy Optimization for Beyond-CMOS Computing Systems
Abstract: The continuous scaling limitations of conventional CMOS technology have accelerated the exploration of alternative computing paradigms for next-generation low-power and high-performance systems. Spintronic logic devices have emerged as a promising solution due to their non-volatility, ultra-low switching energy, high integration density, and compatibility with beyond-CMOS architectures. This research presents a comprehensive modeling and energy optimization framework for spintronic logic devices applied in beyond- CMOS computing systems. The proposed work investigates …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 4, Issue 1, 2026 Read article
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Harnessing Microbial and Phytoremediation Techniques for Sustainable Remediation of Heavy Metals in Black Cotton Soils
Abstract: Black cotton soils, renowned for their fertility and moisture retention capabilities, face significant challenges due to heavy metal contamination, posing threats to both agricultural productivity and environmental integrity. This review paper presents a comprehensive overview of bioremediation strategies aimed at mitigating heavy metal pollution in black cotton soils. The paper underscores the importance of addressing heavy metal (HM) contamination, emphasizing the need for exploring bioremediation techniques, as it sets the …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 193–201 Read article
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Enhancing Customer Engagement with AI-Driven Movie Recommenders: Integrating Neural Collaborative Filtering, Sentiment Analysis, and Conversational Agents
Abstract: In today’s competitive digital landscape, user engagement is a critical factor for the success of entertainment platforms, especially those offering movie recommendations. This study introduces a comprehensive AI-driven framework designed to enhance customer interaction, satisfaction, and loyalty through the intelligent integration of multiple deep learning models. The system combines three core components: Neural Collaborative Filtering (NCF) for generating personalized movie recommendations based on user behavior and preferences, Long Short-Term Memory …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 12, Issue 3, 2025 · pp. 45–54 Read article
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Green Human Resource Management: Awareness, Perception, and Its Impact on Employee Well-being and Work-Life Balance
Abstract: This study explores the growing significance of Green Human Resource Management (Green HRM) and its impact on employee well-being and work-life balance. As organizations face increasing pressure to adopt sustainable and environmentally responsible practices, Green HRM emerges as a strategic approach that aligns ecological objectives with human resource policies. The research aims to assess employee awareness and perception of Green HRM initiatives and how these perceptions influence their job satisfaction, …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 15, Issue 2, 2025 Read article
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Exploring Type-II Diabetes Potential of Phyto-Derived Carbon Dots
Abstract: The integration of phytoconstituents with carbon dots (C-dots) presents a novel and sustainable approach to the development of nanotherapeutics for type 2 diabetes mellitus (T2DM). C-dots, zero-dimensional carbon-based nanomaterials, exhibit unique physicochemical properties including high fluorescence, tunable surface chemistry, biocompatibility, and low toxicity. Their ability to enhance the solubility, bioavailability, and targeted delivery of poorly soluble phytochemicals renders them highly suitable for biomedical applications. This study explores the synthesis of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 08–25 Read article
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Hybrid Machining Processes in Advanced Manufacturing: A Review of Mechanisms and Industrial Applications
Abstract: Hybrid machining processes (HMPs) have gained considerable attention in recent years as an effective approach to address the growing complexity and performance demands of modern manufacturing systems. These processes combine two or more machining techniques—such as mechanical, thermal, chemical, or electrical methods—into a single setup, enabling enhanced productivity, precision, and adaptability, particularly for hard-to-machine materials like ceramics, composites, and superalloys. The integration of distinct energy sources results in synergistic effects …
Published in Journal of Production Research & Management · Vol. 15, Issue 2, 2025 · pp. 19–24 Read article
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Harnessing Deep Learning to Explore Microbial Community Structure and Carbon Storage Capacity in Mangrove Ecosystems: A Framework for Computationally
Abstract: Mangrove ecosystems represent one of the most efficient natural carbon sinks on Earth, functioning as critical blue carbon habitats that sustain diverse microbial communities responsible for biogeochemical cycling and long-term carbon storage. Despite their global ecological significance, accurately quantifying and predicting carbon sequestration in mangrove systems remains challenging due to the complex interactions between microbial diversity, sediment chemistry, and environmental drivers. This study presents a comprehensive and sustainable artificial intelligence …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 1, 2026 Read article
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An Overview of Composite Materials: Historical Development, Classification, and Advancements in Natural Fiber-Reinforced Polymer Composites
Abstract: Composite materials have brought about a paradigm shift in numerous industries by integrating distinct components to improve material performance. Consisting of a matrix and reinforcement, composites synergistically combine the unique properties of each constituent to deliver superior strength, enhanced durability, and remarkable flexibility. These attributes have made composite materials indispensable in diverse fields such as automotive, aerospace, construction, and marine engineering. This article provides a comprehensive exploration of the historical …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 158–175 Read article
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Pharmacokinetics of Levothyroxine and Factors Influencing Its Therapeutic Efficacy in Hypothyroidism: A Comprehensive Review
Abstract: Levothyroxine (LT4) remains the standard therapy for hypothyroidism due to its effectiveness in restoring normal thyroid hormone levels and improving physiological functions. However, its pharmacokinetic profile exhibits considerable variability, which may influence therapeutic outcomes in clinical practice. This review aims to comprehensively evaluate the pharmacokinetics of levothyroxine, including its absorption, distribution, metabolism, and elimination, along with factors affecting its therapeutic efficacy. A structured literature search was conducted using electronic databases, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 Read article
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Unveiling Nature’s Potential: In Silico Exploration and Identification of Herbal Remedies for Major Depressive Disorder Through Molecular Interaction Studies
Abstract: Major depressive disorder (MDD), a globally discussed mental health condition, has drawn significant attention because of its unique and intricate nature. This is marked by the enduring presence of negative emotions stemming from a lack of interest, diminished self-esteem, and excessive rumination. Despite the widespread availability of various antidepressant medications, their effectiveness is hindered by low response rates, prolonged treatment durations, and the prevalence of side effects, such as headaches, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 54–62 Read article
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Generative AI-Based Inverse Design of Sustainable Biodegradable Polymers with Target Mechanical and Thermal Properties
Abstract: The escalating global plastic pollution crisis has intensified the urgent need for sustainable biodegradable polymer alternatives that can match or exceed the performance of conventional petroleum-based plastics while minimizing environmental impact. However, traditional polymer discovery approaches are severely constrained by high experimental costs, protracted development cycles spanning years, and fundamental inability to simultaneously optimize multiple conflicting material properties such as mechanical strength, thermal stability, and degradation kinetics. This study presents …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 Read article
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Evaluation of Building Foundations: A Structural Engineering Perspective
Abstract: This study focuses on the comprehensive assessment and design of building foundations, emphasizing the critical relationship between structural loads and soil properties. The depth of the foundation is determined by analyzing the load exerted on the column and the soil's bearing capacity, both of which play a pivotal role in ensuring stability. Similarly, the foundation base size is calculated based on these parameters to ensure it effectively transfers the load …
Published in Journal of Structural Engineering and Management · Vol. 12, Issue 1, 2025 · pp. 6–18 Read article
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Care Companion: Integrated Personal Health Management App
Abstract: In today's era of rapid technological advancements and the growing need for accessible and efficient healthcare solutions, our healthcare app is emerging as an innovative platform that aims to transform the management of health and well-being. By recognizing the diverse needs of patients, caregivers, and healthcare providers, our app bridges the gap between traditional healthcare practices and modern digital innovations. The comprehensive solution leverages cutting-edge technology to offer a suite …
Published in Journal of Operating Systems Development & Trends · Vol. 11, Issue 2, 2024 · pp. 32–39 Read article
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Integrative Perspectives on Lipoma: Traditional Therapeutics from Siddha, Ayurveda, and Unani with Biomedical Correlates
Abstract: Background: Lipoma is the most common benign soft tissue tumor, with an incidence of approximately 2 per 1,000 individuals annually. Modern biomedicine attributes its pathogenesis to genetic abnormalities like HMGA2 rearrangements and dysregulated adipogenesis via PPARγ pathways. Effective pharmacological therapies are lacking. Traditional Indian systems – Siddha, Ayurveda, and Unani – offer unique perspectives and non‑surgical approaches yet remain underexplored in integrative research. Objective: To critically evaluate the descriptions, pathophysiological …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2026 · pp. 19–33 Read article