Search
811 articles for “Design-Down Approach”
-
The Role of Gut Microbiota in the Health Effects of Fermented Dairy Products
Abstract: The human gut microbiota plays a crucial role in maintaining physiological health, influencing digestion, metabolism, immune function, and even mental well-being. Among dietary interventions aimed at modulating gut microbiota, fermented dairy products have emerged as particularly promising due to their rich content of live microorganisms, bioactive compounds, and nutrients. This review explores the intricate interactions between fermented dairy products and the gut microbiota, highlighting their potential health benefits and underlying …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 14, Issue 2, 2025 · pp. 5–10 Read article
-
Sustainable Materials Management: Strategies for Reducing Waste and Enhancing Resource Efficiency in Construction
Abstract: The construction industry is a critical driver of economic development, but it also plays a significant role in environmental degradation due to its high demand for natural resources and its substantial contribution to global waste production. In response to these environmental challenges, Sustainable Materials Management (SMM) has emerged as a comprehensive framework aimed at promoting resource efficiency, reducing waste, and lowering the overall environmental impact of construction activities. This study …
Published in Journal of Construction Engineering, Technology & Management · Vol. 16, Issue 1, 2026 · pp. 11–23 Read article
-
Pharmacodynamics and Drug–Receptor Interactions: Integrating PK/PD Modeling with Modern Drug Development
Abstract: Understanding drug action requires an integrated perspective of pharmacodynamics and pharmacokinetics, which together determine therapeutic efficacy and safety. This review provides a comprehensive overview of the mechanisms underlying drug action, with particular emphasis on drug–receptor interactions and their role in modulating physiological responses. Drugs exert their effects primarily through interactions with specific biological targets, including receptors, enzymes, ion channels, and transporters, resulting in a spectrum of desired and adverse outcomes. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
-
Debris Flow Kinetics in Planetary Environments: A Systems Perspective
Abstract: Debris flow kinetics in planetary environments represent a critical intersection of geomorphology, fluid mechanics, and planetary science. These gravity-driven flow mixtures of solids, liquids, and gases play a key role in shaping planetary surfaces and recording environmental histories. This study adopts a systems perspective to analyze debris flow behavior across different planetary contexts, emphasizing the interconnected roles of material properties, energy transformations, and environmental forcing. By integrating rheological models with …
Published in International Journal of Universe · Vol. 1, Issue 2, 2025 · pp. 08–17 Read article
-
Hierarchical Computational Modeling of Physical Structure Across Quark, Nuclear, and Atomic Scales
Abstract: We present a modular, multi-scale computational framework that integrates physical modeling and visualization across quark, nuclear, and atomic scales within a unified pipeline. Developed to address the traditional fragmentation between sub-nucleonic, nuclear, and electronic representations, the system provides a continuous data flow and visualization bridge spanning from femtometers to ångströms. The framework consists of three primary modules: a particle-level module illustrating nucleons as confined quark-triplets with effective flux-tube geometries; a …
Published in Research & Reviews : Journal of Physics · Vol. 15, Issue 1, 2026 Read article
-
Impact of Reinforcement Materials and Processing Condition Optimization in Microstructural Engineering of Polymer Composites
Abstract: Polymer mixtures have gotten a lot of attention because they have a unique set of qualities that make them useful in many situations. But the substructure of these alloys is very important for getting the best performance. It looks at how to improve the microstructure of polymer composites by finding the best support materials and working conditions. The choice of strengthening materials is the first thing that is talked about. …
Published in Journal of Polymer & Composites · Vol. 12, Issue 4, 2024 · pp. 102–118 Read article
-
Parametric optimization and validation of novel 3D scanning approach for sustainable manufacturing of patient-specific orthodontic retainers
Abstract: The purpose of the proposed study is to identify the ideal procedure parameters for 3D scanning a denture in order to produce customised orthodontic retainers that can be produced sustainably. However, pilot investigations rarely explore parameters like scanning angle, light intensity, or scanning distance. In order to lower acquisition error, the suggested study examines a method for forecasting the ideal values of the previously indicated scanning parameters. Based on the …
Published in Journal of Polymer & Composites · Vol. 12, Issue 2, 2024 · pp. 265–278 Read article
-
Deep Learning Approach to Produce Artificial Speech (Text-To-Audio)
Abstract: This program utilizes key features of the .NET framework to facilitate smooth text-to-speech conversion and audio playback. Upon execution, users are prompted to input text via a graphical user interface (GUI), which the program converts into speech using the ‘SpeechSynthesizer’ class from the ‘System. Speech.Synthesis’ namespace. The audio that has been synthesized is handled and stored as a WAV file called ‘output.wav’ by utilizing the ‘FileStream’ class, allowing for future …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 12, Issue 1, 2025 · pp. 28–33 Read article
-
Design and Development of a Boundary Alert System for Fishermen
Abstract: This study presents the design and development of a Boundary Alert System for fishermen, employing the Flutter programming language. The system utilizes International Maritime Boundary Line (IMBL) The maritime border system was initiated and developed by the United Nations Convention of the Law of the Seas (UNCLOS). When a fishing vessel approaches within 500 m of these boundaries, the system triggers visual and auditory alerts for the fishermen and sends …
Published in Journal of Mobile Computing, Communications & Mobile Networks · Vol. 11, Issue 1, 2024 · pp. 31–36 Read article
-
CFD Analysis of a Bladeless Propelling Unit for the Drones
Abstract: Conventionally, unmanned aerial vehicles (UAVs) and autonomous aerial vehicles (AAVs) utilize bladed propellers to produce lift, altitude, and thrust for propulsion. Yet, these blades are susceptible to abrasion when they contact external surfaces, resulting in diminished operational efficiency over time. Our ongoing investigation introduces a pioneering approach by integrating bladeless propeller technology, drawing inspiration from Dyson’s Bladeless Fan Theory. This study seeks to address the wear-related shortcomings of conventional propeller …
Published in Recent Trends in Fluid Mechanics · Vol. 11, Issue 3, 2024 · pp. 37–46 Read article
-
Gene Therapy in Modern Medicine: Promises and Challenge in Treating Genetic Diseases
Abstract: Gene therapy is a medical approach that focuses on altering or adjusting an individual’s genes to treat or prevent illnesses. The aim is to repair faulty genes or insert new ones into the body to combat diseases. Gene therapy can involve directly introducing modified or new genes into a patient’s cells or altering the genes already present in the patient’s body. This approach shows potential for treating a range of …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 27–32 Read article
-
Clone-Specific Drug Delivery Systems: Targeted Approaches and Future Clinical Applications
Abstract: Clone-specific drug delivery systems represent a transformative frontier in personalized medicine, addressing the longstanding challenge of clonal heterogeneity within diseases such as cancer, infectious diseases, and autoimmune disorders. Traditional drug delivery platforms often fail to discriminate between pathogenic and healthy cells, leading to systemic toxicity and reduced therapeutic efficacy. In contrast, clone-specific systems aim to selectively target and eliminate disease-driving cellular clones based on unique molecular signatures, thereby improving treatment …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 21–29 Read article
-
Room Light Controller with Bidirectional Visitor Counter
Abstract: With the speed at which technology is developing today, automation is essential for increasing productivity, preserving energy, and enhancing consumer ease. The concept and implementation of an automatic room light controller with a bidirectional visitor counter are presented in this study. By detecting the presence and quantity of people in a room, the device is designed to automatically adjust the lighting, cutting down on wasteful electricity use. Pairs of Infrared …
Published in Journal of Microcontroller Engineering and Applications · Vol. 12, Issue 3, 2025 · pp. 33–37 Read article
-
Augmented Reality Based 3D Drawing from the 2D
Abstract: Students benefit from this approach since it offers an alternative viewpoint on content production and teaching and learning techniques. Managing global projects necessitates the use of techniques and resources to aid in content communication. The development of augmented reality (AR)/virtual reality (VR) content requires a significant amount of time if efficient design and visualization techniques are not employed. The use of highly detailed 3D games that may have required a …
Published in Journal of Multimedia Technology & Recent Advancements · Vol. 11, Issue 3, 2024 · pp. 10–17 Read article
-
Human Skin Abnormality Detection with Process Similarity Criteria Fit Machine Learning Method
Abstract: This method presents a machine learning method that satisfies the defined conditions for healthy waterside beach activities. The boundary conditions of the normal and abnormal radiation spaces were formulated. The objectives of using a Regression Polynomial with Process Similarity Criteria Fit for skin temperature prediction are justified by the analysis of the existing analytical and machine learning approaches. An algorithm for skin temperature prediction using the theories of similarity criteria …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 11, Issue 2, 2024 · pp. 17–24 Read article
-
Design and Implementation of an Online Food Ordering System
Abstract: This study illustrates how the Online Food Ordering System has been tailored specifically to address the operational needs of Hotel Ambika, a semi-urban establishment. The system is designed to offer customers a smooth and interactive experience, allowing them to navigate through an organized menu, personalize their orders, and complete transactions with minimal effort. By using secure payment gateways and a virtual cart for easy order management, the system ensures a …
Published in Journal of Computer Technology & Applications · Vol. 16, Issue 2, 2025 · pp. 106–115 Read article
-
Green and Edge-Aware Computing: Rethinking Cloud Infrastructure for Sustainability
Abstract: Cloud computing has transformed the way organizations access and manage information technology resources, providing flexible, scalable, and cost-efficient services that support today’s data-driven world. Despite these advantages, the rapid expansion of large-scale cloud infrastructures has resulted in rising energy consumption, significant heat generation, and a growing environmental footprint. This research focuses on advancing green cloud computing by examining methods that reduce power usage while maintaining high performance. Key strategies include …
Published in Journal of Computer Technology & Applications · Vol. 17, Issue 1, 2026 · pp. 17–24 Read article
-
Advanced Water Purification Techniques for Sustainable Clean Water Management: A Comprehensive Review
Abstract: The growing global demand for safe drinking water, coupled with increasing pollution from industrialization, urbanization, and agricultural activities, has intensified the need for efficient and sustainable water purification technologies. Conventional water treatment processes often fail to remove emerging contaminants such as pharmaceuticals, microplastics, endocrine-disrupting compounds, and heavy metals. Advanced water purification technologies—including membrane filtration, advanced oxidation processes (AOPs), nanotechnology-based adsorbents, photocatalysis, electrochemical treatment, and bio-inspired purification systems—have emerged as promising …
Published in Journal of Water Pollution & Purification Research · Vol. 13, Issue 1, 2026 · pp. 47–52 Read article
-
Integrative Therapeutics for Antimicrobial Resistance and Autoimmune Disease: Evidence and Pathways
Abstract: Background: Antimicrobial resistance (AMR) is accelerating globally, while autoimmune diseases and adverse drug reactions (ADRs) continue to rise. Ayurveda offers immunomodulatory, antimicrobial, and detoxification‑oriented interventions that may complement biomedical strategies. Objective: To propose a hypothesis‑driven integrative model combining Ayurvedic phytotherapy, panchakarma detoxification, and personalized dosha‑based care with evidence‑based medical management to mitigate AMR emergence, modulate autoimmunity, and reduce ADR incidence. Methods: A synthesis of mechanistic literature on Ayurvedic herbs with …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 2, 2026 · pp. 25–30 Read article
-
Light-Matter Interactions in Molecular Photochemistry
Abstract: Molecular photochemistry explores the ways of molecules interaction with light, absorb photons, and excited‐state processes, and ultimately conversion of photon energy into chemical change. Core concepts of this innovative and relevant field are matter interaction like electronic, vibrational, and rotational transitions; non‐adiabatic couplings; energy & electron transfer; and light–matter coupling in weak and strong regimes. This article briefly surveys the multiplicity of these interactions, from the fundamentals of photon absorption …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 3, Issue 2, 2025 · pp. 33–42 Read article