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1953 articles for “phosphoinositol-3-kinase pathway” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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A Study on Clinical Evaluation of Multi Intervention Therapy for Enhancing Quality of Life in Maintenance Hemodialysis Patients
Abstract: Patients with Chronic Kidney Disease (CKD) receiving maintenance hemodialysis often report a markedly impaired health-related quality of life, largely resulting from factors such as psychological distress, chronic inflammation, and poor nutritional status. Despite its importance as a clinical outcome, HRQOL assessment in dialysis patients has received limited attention. Strengthening comprehensive patient care and optimizing treatment strategies may help reduce complications and promote improved physical, mental, and social well-being. The present …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 3, 2025 · pp. 69–81 Read article
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Domino Reaction for the Synthesis of Nitroolefin Heterocyclic Compound Via Thiazole Formation Followed by Claisen Rearrangement
Abstract: The Baylis-Hillman adducts derived from nitroolefins have been conveniently transformed into Claisen rearrangement. These substances, which include benzothiazole moiety, are very biologically reactive substances. This novel nitro derivative of 2-((E)-2-nitro-3-phenylallyloxy)-3-ethoxybenzaldehyde was simply treated with mole percentage of 2-(2-(2-aminophenyl) disulfanyl) benzenamine in melt reactive condition. Hence this novel 2-(benzo[d]thiazol-2-yl)-6-ethoxy-4-((E)-2-nitro-3-phenylallyl)phenol core unit compounds was very intrusting and new opportunities for the preparation of closely related to the different [3,3] sigmatropic rearrangements related …
Published in Journal of Modern Chemistry & Chemical Technology Read article
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Modal Analysis of RC Masonry Infill Model and Prototype Frames with Openings
Abstract: Modal evaluation is the technique of figuring out the inherent dynamic traits of the shape in phrases of herbal frequencies and mode shapes and the usage of them to create a mathematical version for its dynamic behavior. The dynamics of a structure is defined by frequency and position. Modal evaluation offers the records regarding to exceptional modes of vibration, exceptional form that may be taken up via way of means …
Published in Journal of Structural Engineering and Management Read article
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Mechanical Performance Degradation of Naturally Aged Nitrile Butadiene Rubber in Low Frequency Range...
Abstract: For good mechanical design, damping is often still an invisible requirement. Nitrile Butadiene Rubber (NBR) has a wide range of applications as a damping and sealing material. To offer the long-term service of NBR, it is important to estimate the degradation of modal properties under complex mechanical and environmental loading. The present work aims to correlate the experimental data with generalized higher-order Maxwell models and curve fitting techniques to find …
Published in Journal of Polymer & Composites Read article
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High Frequency Design Approach and Feasibility Study of HBT Based W-band (90.0 GHz-100.0 GHz) Amplifier using 130 nm SiGe Based BiCMOS Technology
Abstract: This paper present high frequency design approach and feasibility study of HBT (Hetero Junction Bipolar Transistor) based two-stage cascode amplifiers at W-band (90.0 GHz-100.0 GHz). The proposed amplifier has design using 130 nm SiGe based BiCMOS technology. This paper used low cost technology for designing of w-band amplifier and this is novelty of this paper. The schematic design and feasibility study has been carried out using Cadence software. The selection …
Published in International Journal of Digital Communication and Analog Signals Read article
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Design and Simulation of Forging Die Towards Improving Life of Closed Die
Abstract: Forging is the metal forming process which is used for forming complex shaped component with geometrical accuracy. More than fifty percent of the forgings are processed through this way. Forged components required in many engineering sectors, most of them in the automotive sector. The majority of the safety critical component and load bearing structural components are process through it. By using forging process production of complex component is faster with …
Published in Journal of VLSI Design Tools and Technology Read article
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Improvements in Analog Performance of Dual Metal Gate based Silicon-on-Insulator Junctionless Transistor with Pocket Doped Window
Abstract: This paper elucidates the impact of the pocket doped window on the analog performance of dual metal gate based silicon-on-insulator junctionless transistor (DMG SOIJLT). The analog parameters of the proposed SOIJLT are compared with DMG based conventional SOIJLT. The findings of analog performance comparison reveal that transconductance (gm), transconductance generation factor (TGF), output conductance (gd), output resistance (r0), intrinsic gain (AV), and cut-off frequency (fT) have improved for DMG PD-SOIJLT …
Published in Journal of Microelectronics and Solid State Devices Read article
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Assessing the Influence of Aggregates and Cement Type on the Properties of Roller-compacted Concrete
Abstract: Roller-compacted concrete (RCC) pavement is suitable for heavy traffic and harsh environment. In the present investigation, RCC slab samples have been prepared using two types of aggregates (crushed and rounded), and two types of cement binder (ordinary Portland and sulphate resistant). Cubes and beam specimens have been extracted from the slab samples with the aid of diamond saw. Specimens were tested for bulk density, ultrasound pulse velocity, compressive and flexural …
Published in Trends in Transport Engineering and Applications Read article
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Evaluation of Tectona Grandis Leaf Extract As A Green Corrosion Inhibitor for Aluminium in 1M NaOH
Abstract: A kind of tropical hardwood tree called the Tectona grandis tree that is indigenous to India. The name "teak tree" is another common name for this kind of tree. It is a member of the plant family that is referred to as Lamiaceae. The primary purpose of this research is to investigate whether or not the plant extract has a corrosion-inhibiting quality. In this study, an aqueous extract of Tectona …
Published in Journal of Polymer & Composites · Vol. 2, Issue 2, 2023 · pp. 41–50 Read article
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A Study on the Impact of GPS-Derived Tropospheric Delay over some Nigerian Stat
Abstract: The effect of GPS-derived tropospheric delay on radio propagation oversome Nigerian stations is examined. The stations are located in the African equatorial region, and include: Abuja (8.9°N, 7.4°E), Akure (7.3°N, 5.2°E), Enugu (6.5°N, 7.5°E), Lagos (6.5°N, 3.4°E), and Port Harcourt (4.8°N, 7.0°E). This is the first study in the African equatorial region that uses in-situ meteorology measurements as well as GPS satellite measurements to present the impact of tropospheric delay …
Published in Research & Reviews : Journal of Space Science & Technology Read article
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Phase Behaviour Study of a Mesogen in a Solvent Role of Molecular Rigidity and Configurational Entropy
Abstract: The phase behaviour of a nematogen 4’-n-pentyloxy-4-biphenylcarbonitrile (POBPCB) has been studied with respect to the translational and orientational motions. The charges of atoms and their dipole moments have been estimated by implementing the complete neglect differential overlap (CNDO/2) method. The long-range interactions have been analyzed using modified Rayleigh- Schrodinger Perturbation theory together with the multicentred-multipole expansion scheme. The “6- exp” potential function has been considered to study the short-range interactions. …
Published in Research & Reviews : Journal of Physics Read article
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Yield Loss Assessment in Common Bean (Phaseolus vulgaris L.) due to Ascochyta Blight (Phoma exigua var. diversispora (Bubak) Boerema) Disease
Abstract: Ascochyta blight (Phoma exigua var. diversispora (Bubak) Boerema) causes a severe, rapidly developing disease on common beans (Phaseolus vulgaris L.) that can bring about complete plant defoliation and extensive yield loss. Studies were conducted in Rwanda to quantify the yield loss attributed to bean ascochyta blight on 64 common bean genotypes including bush and climbing. Using a split plot design, trials were conducted at three locations, where ascochyta disease is …
Published in Research & Reviews : Journal of Agricultural Science and Technology Read article
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Molecular Characterization of Circulating Rota Viral Strain causing infantile diarrhoea in Tripura, North East India
Abstract: Introduction: North Eastern India is geographically distinct from rest of India and the trend of Rota viral diarrhoea among children below 5 years of age group is not well studied yet. The Government of India introduced the oral rotavirus vaccine (ROTAVAC) in 2016 as part of the Universal Immunization Programme in different parts of India. Objective: (1). To determine the proportion of circulating Rotavirus strains causing acute viral gastroenteritis (AGE) …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 11, Issue 3, 2021 · pp. 6–13 Read article
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Development of Zinc Gluconate Vitamin C Effervescent Tablet for Immunity Improvement and Management of Corona Virus Disease (COVID-19)
Abstract: The global pandemic of coronavirus disease- 2019 (COVID-19) continues to pose a threat to people, societies, and economic and healthcare systems. COVID-19s progression and lethality are determine by the host immune system, as is the case with many other diseases. revolutionary idea that has been used to treat other diseases is the control of inflammatory response and cytokine production based on immunonutrition. Some COVID-19 clinical trials are now using zinc, …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 1, 2024 Read article
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Breast Feeding Practices Among Rural Women
Abstract: Introduction: Breastfeeding is an unequalled way of providing ideal food for the healthy growth and development of infants. As per the national family health survey-3 (NFHS-3), only 46% of the Indian infants between 0 and 6 months are exclusively breastfed. Hence the following study was done to know the practice of breastfeeding in mothers of rural and urban areas of India. Method- The study was carried out in a rural …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 01–08 Read article
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Enhancing the Strength of Black Cotton Soil with Enzyme and Industrial Waste
Abstract: Expansive soils are troublesome and prone to ground movements, which can cause substantial damage to underlying buildings as well as a loss in bearing capacity. Moisture fluctuation activates the expansive character of soils, causing it to swell and shrink. This has long been known in geotechnical engineering. To treat expansive soils, a variety of stabilizing additives such as lime, cement, and fly ash have been employed. In recent years the …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 1, Issue 1, 2023 · pp. 1–11 Read article
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Review Descriptive Programme on Knowledge Regarding Diabetes Mellitus
Abstract: Context: A research study was conducted to assess the knowledge and prevalence of diabetes mellitus among elderly individuals in selected areas of Jalandhar, Punjab. The study also aimed to develop an informative guide sheet. Objectives: (1) To assess the level of understanding about diabetes mellitus among elderly individuals in the selected regions. (2) To determine the prevalence rate of diabetes mellitus among elderly individuals in the selected areas. (3) To …
Published in International Journal of Community Health Nursing And Practices · Vol. 1, Issue 2, 2023 Read article
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Effect of Formaldehyde Treatment on the Barrier and Mechanical Properties of Oat Protein Films
Abstract: Oat protein 5% with 40% glycerol as a plasticizer was used to prepare edible films, and formaldehyde was chemically added to the film's solution at four concentrations. The films' barrier and mechanical properties were then investigated. The films were characterized by being medium transparency, homogeneous, odorless, and with a thickness ranging between 0.12 and 0.15 mm. It was also observed that the water vapor permeability decreased whenever the concentration of …
Published in Journal of Polymer & Composites · Vol. 11, Issue 2, 2023 · pp. 1–8 Read article
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Study of Electrochemical and Mechanical Properties of Graphene/HAp Composite Coating on Ti-13Nb-13Zr Alloy via Electrophoretic Deposition for Biomedical Application
Abstract: Titanium-13niobium-13zirconium alloy has widespread potential in biomedical applications due to its high degree of biocompatibility, favourable mechanical properties, high corrosion resistance, and high possibility of osseointegration. The surface was improved by electrophoretic deposition method using hydroxyapatite and graphene (5 g nanoHAp) (5 g nanoHAp+0.06 nanoGr) and suspended in ethanol solution at different conditions of time (1, 3, and 7 minutes) and voltage (50, 70, and 100 V). The effect of …
Published in Journal of Polymer & Composites · Vol. 11, Issue 2, 2023 · pp. 91–106 Read article
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A Computational Study to Elucidate the Phytochemicals as An Antagonist Against Pruritis in Psoriasis
Abstract: Objective: Psoriasis is a chronic, non-contagious, auto-immune skin disorder that causes inflammation, pain, and itching in the affected areas. The etiology of this condition is not entirely understood, and while there are treatments available to manage the symptoms, there is currently no cure. The Transient receptor potential cation channel, subfamily Vanillin, member 3 (TRPV3), present in keratinocytes, allegedly had a part in the development of psoriasis-related pain and itching. Specifically, …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 49–61 Read article