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940 articles for “patient”
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Anaphylaxis: Pathophysiology, Risk Factors, and Clinical Management
Abstract: Anaphylaxis is a syndrome characterized by broncho-constriction, vasodilatation, and hypovolemia, potentially fatal exposure to known or unknown antigens. It can be an immune-mediated (IgE & non-IgE) disease. Immunoglobulin G (IgG), complement related (C3a/C5a), bradykinin, leukotrienes, prostaglandin E2, and ligands of certain G-protein coupled receptors (GPCR) can directly activate mast cells, basophils, eosinophils, neutrophils, endothelial cells and smooth muscles. Serum tryptase level during episodes of anaphylaxis, skin test, and basophil activation …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 · pp. 1–11 Read article
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Graphene-Polymer Nanocomposites for Drug Delivery Applications
Abstract: Graphene-polymer nanocomposites (GPNCs) have gained significant attention in drug delivery due to their exceptional physicochemical properties, including high surface area, mechanical strength, tunable functionality, and biocompatibility. These nanocomposites integrate graphene derivatives, such as graphene oxide (GO) and reduced graphene oxide (rGO), with biocompatible polymers to enhance drug loading efficiency, stability, and controlled release. Various natural (chitosan, alginate) and synthetic (PLGA, PEG, PCL) polymers are used to functionalize graphene, enabling targeted …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 362–374 Read article
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U-Net Based Approach for Automated Brain Tumor Classification
Abstract: Brain tumor detection and identification play vital roles in diagnostic procedures in the field of medicine, with the conventional analysis of MRI images requiring a lot of time and also subject to variability. The proposed study involves the use of a CNN-U-Net based approach for brain tumor detection and identification automatically. The study uses a database of 3,064 contrast-enhanced T1-weighted MRI images from 233 patients with the tumors of meningioma, …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 2, 2025 Read article
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Evaluating the Role of Platelet Indices, with a Focus on Immature Platelet Fraction (IPF), in Differentiating Hyper-Destructive and Hypo-Productive Thrombocytopenia: A Study from Ludhiana, Punjab, India
Abstract: Background: Thrombocytopenia, characterized by a reduction in platelet count, is commonly observed in clinical settings. Its etiology can be broadly classified into hyper-destructive thrombocytopenia, where platelets are destroyed at an accelerated rate, and hypo-productive thrombocytopenia, where platelet production is impaired. Differentiating between these two causes is essential for effective management. The Immature Platelet Fraction (IPF) has emerged as a promising non-invasive diagnostic tool to distinguish these causes. Objectives: The primary …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 2, 2025 Read article
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A Brief Review on Herbal Excipients
Abstract: Natural or herbal excipients are significantly more advantageous than their synthetic equivalents because they are readily available, non-toxic, and less expensive. The pharmaceutical industries are becoming more interested in using these herbal excipients – mainly polymers of natural origin – in formulation development because of growing knowledge of them. The purpose of this study is to provide light on the possibility of using natural excipients, which are biocompatible and able …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 2, 2025 · pp. 5–14 Read article
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Pharmacovigilance: Enhancing Drug Safety Through Technology
Abstract: The research and practices surrounding the identification, evaluation, and avoidance of hazardous medication responses in people are known as pharmacovigilance. Pharmacovigilance has been defined as a kind of ongoing observation of side effects and other safety-related features of medications that have previously been introduced to the market. Pharmacovigilance has been shown to be crucial in promoting the sensible use of medications by disseminating knowledge about the negative effects that pharmaceuticals …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 38–44 Read article
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Advances in Polymer-Based Orthodontic Materials for Enhanced Treatment Efficiency
Abstract: Polymers, particularly shape-memory polymers, fiber-reinforced composites, and elastomeric materials, provide enhanced mechanical properties such as flexibility, durability, and controlled force application, leading to improved treatment outcomes. These materials offer superior biocompatibility, reducing irritation and discomfort for patients while ensuring efficient and predictable tooth movement. It is important to note one of the key advancements in orthodontics is the use of shape-memory polymers, which can respond to temperature or external stimuli, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 1016–1024 Read article
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Engineered Polymer Composites for Non-Surgical Lip Posture Correction in Facial Paralysis
Abstract: Facial paralysis presents significant functional and aesthetic challenges, particularly through lip posture deficits such as drooping and drooling, often inadequately addressed by traditional surgical or drug-based interventions, especially in debilitated patients. This study explores the application of engineered polymer composites in a novel, non-surgical lip posture corrector designed to statically suspend and correct lip position without requiring surgical or dental support. The device utilizes a precisely formulated blend of polymethylmethacrylate …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 Read article
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Live Epidemiological Tracking of COVID-19 in Senegalese Participants of the Hajj
Abstract: Background: Since the COVID-19 outbreak, global efforts have focused on controlling the disease. However, intense cross border movements pose a risk for the emergence of new SARS-CoV-2 strains. A recent example is the detection of cases among the 2024 Senegalese pilgrims returning from Mecca, Saudi Arabia. Investigations of these cases have revealed genomic evolution of the virus. The lack of surveillance may lead to the emergence of high-threat strains. This …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 8–16 Read article
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The Role of Artificial Intelligence in Mental Health: Applications in Neurodegenerative Disorders
Abstract: Artificial intelligence (AI) has significantly changed many aspects of medical care, particularly the early evaluation, therapy, and management of neurodegenerative illnesses like Alzheimer's, disease, Parkinson's diseases, and Huntington's diseases. The current research explores the application of AI in mental health with respect to neurological disorders, especially advancements in cognitive examination, neuroimaging analysis, predictive modeling, and customized therapy modalities. Artificial intelligence (AI) systems have shown enormous potential in detecting minute biomarkers …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 3, 2025 · pp. 34–40 Read article
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Multimodal Disease Detection Using Deep Learning
Abstract: Artificial Intelligence (AI) is playing an increasingly pivotal role in modern healthcare, particularly in improving the speed and accuracy of disease detection. With the evolution of Machine Learning (ML), Deep Learning (DL), and high-performance computing, AI-based solutions are now capable of processing extensive medical datasets, ranging from patient records to diagnostic images, with remarkable efficiency. These systems offer immense potential for early intervention, improved clinical decision-making, and alleviating pressure on …
Published in Journal of Computer Technology & Applications · Vol. 16, Issue 2, 2025 · pp. 129–139 Read article
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Leveraging Artificial Intelligence (AI) and Digitalization of Community Health Screening in Unani Medicine: Bridging Tradition with Technology – A Perspective Review
Abstract: AI and digitalization bring a great opportunity for reforming and even improvement of traditional healthcare systems in Unani physiology. This review, therefore, observes the important role played by AI and digital health solutions in modernizing health screening and diagnostic procedures in Unani medicine, thereby bridging traditional healing practices with contemporary technological advancement. AI refers to the advantages that may accrue via wearable health devices and telemedicine in real-time monitoring, early …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 2, 2025 · pp. 20–31 Read article
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Polymer Chemistry and Composite Materials in Biomedical Applications
Abstract: The integration of polymer chemistry and composite materials has revolutionized biomedical applications. Recent advancements in polymer synthesis, functionalization, and nanotechnology have further expanded their applications, leading to significant improvements in biocompatibility, biodegradability, and mechanical performance. These polymeric carriers protect bioactive compounds from enzymatic degradation, enable controlled drug release, and improve therapeutic efficacy. The integration of polymer chemistry with nanotechnology has enabled the development of highly efficient, targeted therapeutic systems that …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 413–419 Read article
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Advancements In Technologies and Their Impacts On Mental Health Care With Special Reference to Ethical Considerations
Abstract: Mental health technology has seen remarkable progress in recent years, leveraging digital tools to improve diagnosis, treatment, and patient engagement. This review article examines the evolving role of technological innovations in mental health care, drawing insights from a range of scholarly reviews and research articles that explore the intersection of mental health and technology. Key advancements highlighted in this paper include artificial intelligence (AI), telemedicine, mobile health applications, serious games, …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 Read article
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Biodegradable Polymer Composite Materials for Long-Term Drug Release in Pharmacotherapy
Abstract: Biodegradable Polymer composite materials are a promising choice for controlled drug delivery because they let medicine be released slowly over time during treatment. These structures, which are made from safe, recyclable plastics, work well to make sure that drugs stay in the body for a long time. This means that patients will take their medicine less often and more consistently. As the body breaks down these structures, the drug inside …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 533–546 Read article
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4D Printing in Drug Delivery: Application of Shape- Morphing Materials in Controlled Drug Release
Abstract: Four-dimensional printing technology has transformed the pharmaceutical landscape, offering unprecedented opportunities for innovation in drug development and delivery. This emerging technology enables the creation of complex geometries and customized structures, facilitating the design of personalized medications tailored to individual patient needs. Personalized dosing and drug release profiles, customized pill shapes and sizes for improved swallowability. Enhanced drug solubility and bioavailability, rapid prototyping and testing of pharmaceutical products. Development of complex …
Published in Trends in Drug Delivery · Vol. 12, Issue 3, 2025 · pp. 08–16 Read article
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Chronic Kidney Disease: A Comprehensive Review
Abstract: Chronic Kidney Disease (CKD) is a progressive condition characterized by a long-term decline in kidney function, leading to a gradual deterioration of the kidneys' ability to filter waste and maintain fluid balance. It is diagnosed when the Glomerular Filtration Rate (GFR) falls below 60 ml/min/1.73 m² or when there is evidence of kidney damage (such as proteinuria) lasting for 3 months or more. The most common causes of CKD are …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 37–42 Read article
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Electroconvulsive Therapy in the Management of Schizophrenia: A Systematic Review in Emergency Nursing Practice
Abstract: Electroconvulsive therapy (ECT) is a well-established treatment for various psychiatric disorders, including schizophrenia, particularly in cases where patients are resistant to conventional treatments. Schizophrenia, a chronic and severe psychiatric disorder, often presents with a combination of positive symptoms (such as hallucinations and delusions), negative symptoms (such as social withdrawal and emotional blunting), and cognitive impairments. While antipsychotic medications are the primary treatment, approximately 20–30% of individuals with schizophrenia do not …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 43–48 Read article
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A review on Design of Gene Therapy and Its Potential for Craniofacial Regeneration
Abstract: One of the most talked-about topics of the 21st century is gene therapy, which holds the promise of treating many diseases. Current gene therapy research explores a wide range of potential treatments, such as enhancing the body’s immune response to tumors, promoting the formation of new blood vessels in the heart to mitigate heart attacks, and preventing HIV replication in AIDS patients. Gene therapy involves the introduction, alteration, or replacement …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 2, 2025 · pp. 6–12 Read article
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Polymeric Materials in Assistive Devices for Cerebral Palsy: Advances and Applications
Abstract: The neurological condition known as cerebral palsy (CP) impairs muscle coordination and movement often necessitating assistive devices for mobility, support, and rehabilitation. These devices are crucial for enhancing CP patients' quality of life by boosting their independence, comfort, and overall functionality. Recent advancements in polymer chemistry have revolutionized the development of assistive devices, offering enhanced flexibility, durability, and biocompatibility. The integration of polymeric materials in orthotic supports, adaptive braces, and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 316–322 Read article