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837 articles for “Clinical”
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Prevention of Primary Hypertension Through Asbab-e-Sitta Zaruriya: A Therapeutic Paradigm
Abstract: Hypertension, defined as blood pressure elevation to a level that increases the risk of organ damage, Recent guidelines classify hypertension as systolic blood pressure ≥130 mmHg or diastolic blood pressure ≥80 mmHg, distinguishing between primary (essential) and secondary forms. It affects over one billion individuals globally and contributes to approximately 9.4 million deaths annually. Nearly 63% of total deaths in India are due to non-communicable diseases, of which 27% are …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 11, Issue 3, 2024 · pp. 13–20 Read article
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Intelligent Medical Devices and Robotics in Modern Healthcare: Technological Advancements and Economic Considerations
Abstract: The integration of robots and intelligent medical devices in intensive care units (ICUs) represents a significant advancement in healthcare technology. These systems, including robotic assistants, automated monitoring tools, and AI-powered diagnostic devices, are designed to enhance patient care, streamline workflows, and reduce human error. Robots in the ICU can assist with routine tasks such as medication delivery, patient repositioning, and even basic surgeries, enabling healthcare professionals to focus on critical …
Published in Journal of Advancements in Robotics · Vol. 11, Issue 3, 2024 · pp. 18–27 Read article
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Human Milk and Infant Growth: A Systematic Review of Nutritional Outcomes
Abstract: Human milk is recognized as the optimal source of nutrition for infants, playing a critical role in their growth and development. This systematic review explores the evidence linking human milk consumption to various growth parameters in infants, including weight gain, length, and head circumference while considering the influencing factors of prematurity and health status. The composition of human milk, rich in essential macronutrients (proteins, fats, carbohydrates) and micronutrients (vitamins and …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 13, Issue 3, 2024 · pp. 1–6 Read article
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Development of a Polymeric Detection System for Salivary Annexin-1: A Potential Tool for Point-of-Care Diagnostics in Periodontal Disease
Abstract: Salivary annexin-1, a protein with anti-inflammatory properties, has emerged as a potential biomarker for periodontal disease. However, current detection methods, like ELISA, are often complex and require laboratory settings. This study explores the development of a novel polymeric detection system for the rapid and sensitive identification of salivary annexin-1. This system could leverage the unique properties of polymers to create a point-of-care diagnostic tool for: (1) early detection and monitoring …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 101–110 Read article
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Exploring the Complexities of Parkinson’s Disease
Abstract: Parkinson’s disease (PD) is a neurological disorder, primarily affecting older adults, marked by both motor and non-motor symptoms. This review explores PD as a multisystem disorder that influences the central, enteric, and autonomic nervous systems, along with the immune system and gastrointestinal tract. Key pathogenic features include the degeneration of dopamine-producing neurons in the substantia nigra and the formation of Lewy bodies containing misfolded α-synuclein proteins. The bradykinesia, tremors, stiffness, …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 3, 2024 · pp. 1–8 Read article
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Study of Lipid Profile and Its Correlation with Coronary Angiogram Finding in a Tertiary Care Hospital in an Urban Setting
Abstract: Coronary artery disease (CAD) is a major global health concern caused by the constriction or blockage of the coronary arteries, which can result in serious cardiovascular events. This study looks at the relationship between lipid profiles and the severity of CAD as measured by coronary angiography in patients in a tertiary care hospital. The study focuses on dyslipidemia as a major risk factor for CAD, emphasizing the importance of efficient …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 106–118 Read article
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A Community-Based Study to Assess: The Aggravating Factors and Treatment Choices in Youth with Acne
Abstract: Background and Aim: Acne vulgaris is a common dermatological condition affecting youth worldwide. While its pathogenesis is well-understood, individual experiences with aggravating factors and treatment choices vary. This study aimed to evaluate self-reported factors aggravating acne and determine treatment choices among youth with acne while assessing the correlation between self-perceived and clinically assessed acne severity. Methodology: A cross-sectional survey was conducted with 390 participants aged 18–24 suffering from acne. Data …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 3, 2024 · pp. 1–8 Read article
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Evaluation of Polysaccharide-Based Membranes for Transdermal Drug Delivery in Chronic Pain Management
Abstract: In order to improve treatment effectiveness and patient compliance, chronic pain management is still a major challenge in modern healthcare, requiring creative medication delivery methods. The potential of polysaccharide-based membranes for transdermal drug delivery is assessed in this work, with particular attention to chitosan, alginate, and hydroxypropyl methylcellulose (HPMC). Fourier-transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) were two characterization techniques used to assess the membranes' physical and chemical …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 28–38 Read article
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Bio-Inspired Membranes in Oral Drug Delivery: A Pathway to Enhanced Permeability and Targeted Therapy
Abstract: Bio-inspired membranes in oral drug delivery represent a significant advancement in pharmaceutical technology, harnessing principles of natural biological systems to improve drug permeability, bioavailability, and targeted release. This review discusses the design, materials, and fabrication techniques used in bio-inspired membranes, with a focus on materials like chitosan, silk fibroin, and synthetic polymers that mimic biological structures. By exploring the mechanisms of drug permeation, such as mucoadhesion and selective permeability, bio-inspired …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 39–52 Read article
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Development of a Novel Therapeutic Approach Using RNA Interference for Targeting Viral Genes
Abstract: RNA interference (RNAi) is a ground breaking therapeutic strategy that holds immense promise for targeting viral genes in the treatment of viral infections. This approach leverages the natural gene-silencing mechanisms of RNAi to inhibit viral replication and expression at the molecular level, providing a precise and adaptable method to counteract viral pathogens, including influenza, HIV, and hepatitis viruses. Recent advancements in RNAi technology have enabled the development of highly specific …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 12–22 Read article
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The Role of Natural Products in Antiviral Drug Discovery: Insights into Mechanisms and Therapeutic Potential
Abstract: Drug discovery has always relied heavily on natural sources, especially when it comes to creating antiviral medications. This review explores the therapeutic potential of various natural products, including plant extracts, marine compounds, and microbial metabolites, in the fight against viral infections. We examine the mechanisms of action by which these natural compounds exert their antiviral effects, including direct inhibition of viral replication, modulation of host immune responses, and interference with …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 36–47 Read article
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Targeting TNFSF4 in the Management of Systemic Lupus Erythematosus
Abstract: Systemic lupus erythematosus (SLE) is a multifaceted autoimmune disorder that remains a significant challenge for both healthcare providers and researchers. Despite advances in understanding its mechanisms, finding effective therapies is still difficult. This review highlights a potential therapeutic target in SLE research: tumor necrosis factor superfamily member 4 (TNFSF4), also referred to as OX40L. We explore how TNFSF4 contributes to SLE development, looking at its role in immune system regulation …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 3, 2024 · pp. 6–14 Read article
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Comprehensive Care in COPD: Integrating Non-Pharmacological Treatments in COPD
Abstract: The substantial worldwide respiratory disorder known as chronic obstructive pulmonary disease (COPD) calls for multifaceted care approaches in addition to medicines. The incorporation of alternatives to drugs into chronic pulmonary disease care is the main topic of this article, as it plays a crucial role in enhancing the lives of patients. Pulmonary rehabilitation, exercise training, nutritional support, psychological support, oxygen therapy, and surgical or interventional procedures are some of the …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 3, 2024 · pp. 12–18 Read article
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Toward Comprehensive Immunization: The Role of Combined COVID-19 and Influenza Vaccines in Public Health
Abstract: The emergence of multi-pathogen vaccines, particularly those combining protection against COVID- 19 and influenza, marks a significant advancement in immunization efforts. These combination vaccines have the potential to streamline vaccination processes, improve vaccine uptake, and reduce the burden on healthcare systems by offering a single dose that targets both viruses. COVID-19 and seasonal influenza are major public health concerns, with overlapping symptoms and seasonal patterns that justify the rationale for …
Published in International Journal of Vaccines · Vol. 2, Issue 1, 2025 · pp. 9–17 Read article
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Assessment of Women's Knowledge of Mastitis at Indus International Hospital, Punjab
Abstract: Mastitis is a non-cancerous inflammatory condition of the breast, often resulting from infection, which can impact the mammary gland's structures. It is a relatively frequent condition, affecting between 5% and 33% of women during lactation at some point in their lives. Typical clinical signs include pain in one breast, redness (erythema), and swelling, often accompanied by flu-like symptoms such as fever, chills, and body aches. Upon examination, the affected breast …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 3, 2024 Read article
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Restoring Swallowing Freedom: A Triumph Over Achalasia Cardia Type III- A Case Report
Abstract: This case report explores the rare occurrence of achalasia cardia in a 24-year-old male in India, highlighting the unique challenges in diagnosis and treatment. The atypical demographic and the efficacy of laparoscopic Heller's myotomy with Dor's fundoplication underscore the importance of reporting such cases. The background reveals an unusual presentation of achalasia cardia in a 24-year-old male at Ahmedabad, Gujarat, India, justifying its documentation due to the infrequency of this …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 3, 2024 · pp. 1–5 Read article
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Decompensated Liver Failure and Acute Renal Failure in a Patient with Chronic HBV,HCV, and HIV Infections
Abstract: This case study focuses on a 30-year-old male patient suffering from decompensated liver failure and acute renal failure, complicated by chronic hepatitis B (HBV), hepatitis C (HCV), and HIV/AIDS. Presenting with severe abdominal pain, nausea, and general weakness, the patient had a history of alcohol and intravenous drug use, leading to chronic liver disease and acute renal failure. Despite aggressive interventions, including intravenous antibiotics and fluid therapy, his condition worsened …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 17–23 Read article
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Complex Tuberculous Meningitis: A Case Series Highlighting Rare Co-infections and Severe Complications
Abstract: This case series presents two complex cases of tuberculous meningitis (TBM) with different complications, illustrating the diverse clinical presentations and management challenges of this disease. Case 1 involves an 18-year-old female with TBM complicated by cryptococcal co-infection, while Case 2 describes a 64-year-old female with TBM complicated by obstructive hydrocephalus and secondary bacterial infections. Both patients had been on anti-tubercular therapy before presentation. Diagnostic approaches included cerebrospinal fluid analysis, cultures, …
Published in International Journal of Pathogens · Vol. 1, Issue 2, 2024 · pp. 1–7 Read article
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Malaria Diagnosis through Conventional Methods: A Comprehensive Review
Abstract: The incidence of drug-resistant parasite strains is rising, there is an apparent increase in the number of cases of malaria worldwide, and in a small number of cases and there has been a dramatic rise in international migration and travel. Over 1 million people die from malaria every year; 90% of these deaths are in African children, who live in tropical and subtropical regions. Although there are now efficient techniques …
Published in International Journal of Pathogens · Vol. 1, Issue 2, 2024 · pp. 8–14 Read article
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Amlodipine induced peripheral edema and gingivitis – A case report.
Abstract: Calcium channel a group of drugs used to treat heart disorders are called blockers. These drugs dilate blood vessels and improve blood flow to heart, these works by preventing calcium flow through ion -specific (L- type) calcium channels in the cell membrane. Amlodipine, a calcium channel blocker in the dihydropyridine class, can cause peripheral edema and drug-induced gingivitis in some patients. In this case, the patient experienced swelling in the …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 45–49 Read article