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1074 articles for “Mechanical systems”
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Decoding Innate Immunity: Mechanisms, Components, and Clinical Implication
Abstract: Innate immunology represents the body's first line of defense against pathogens, acting as a rapid, non-specific response to a wide array of microbial invaders. This part of the immune system depends on pattern recognition receptors (PRRs) to identify pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), leading to the activation of immune cells such as macrophages, dendritic cells, and neutrophils. The innate immune system also plays a crucial role …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 Read article
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Dynamic Simulation of Load-Responsive Vapor Compression Refrigeration Systems
Abstract: Because of their dependable operation and effectiveness, vapor compression refrigeration systems, or vapor compression refrigeration (VCRS), have become popular in commercial, industrial, and residential settings. However, under different thermal loads, classic vapor compression refrigeration (VCR) systems may perform less well in that they are usually built for steady-state conditions and run at consistent speeds. In order to improve a load-responsive VCR system’s flexibility, energy efficiency, and response to changing cooling …
Published in Journal of Refrigeration, Air conditioning, Heating and ventilation · Vol. 12, Issue 2, 2025 · pp. 32–37 Read article
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Automatic Seed Planting Using a Controller
Abstract: Agriculture is a critical sector that requires continuous innovation to meet the increasing global demand for food. Traditional seed planting methods often involve labor-intensive processes that are time-consuming and prone to inefficiencies. This project presents an automatic seed planting machine that integrates ESP32 microcontroller technology with various sensors and actuators to enhance the precision, speed, and efficiency of seed planting. The system is designed to automate seed dispensing, soil digging, …
Published in Journal of Electronic Design Technology · Vol. 16, Issue 2, 2025 · pp. 1–8 Read article
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Role of Electron Donors in MgCl2 Supported Ziegler-Natta Catalysis: DFT Approach
Abstract: An insight into the nature of carbonate-based electron donors in high-activity MgCl2 supported Ziegler-Natta (Z-N) catalysts has been studied and compared with conventional phthalate and diether systems by employing density functional theory (DFT) calculations. In the catalyst activation (one of the important processes to produce the active catalyst sites), the conventional monometallic and recently characterized bimetallic (TiCl2(Et)–Cl–AlEt2) active site are studied in the presence/absence of electron donors. These active sites …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 2, 2025 · pp. 51–81 Read article
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Polyurethane: Chemistry, Production, Applications, and Future Prospects—An Overview
Abstract: Polyurethane (PU), a class of versatile polymers, has emerged as one of the most significant materials in modern industry owing to its remarkable mechanical strength, elasticity, durability, and resistance to abrasion, chemicals, and environmental degradation. Its wide range of tunable properties has made PU indispensable across multiple sectors, including fashion, automotive, manufacturing, biomedical, coatings, and construction. This review emphasizes the diverse applications of polyurethane and explores how its unique chemistry …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 3, 2025 · pp. 17–25 Read article
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Quantum Mechanics: Revolutionizing Pharmaceutical Sciences
Abstract: Quantum physics and pharmacy have generally been regarded as distinct areas—one investigates the microlevel behavior of non-living matter while the other concentrates on intricate biological systems. Nevertheless, progress in life sciences has increasingly depended on molecular-level insights, whereas quantum physics has advanced beyond basic principles to impact real-world uses. This intersection provides new opportunities for, pharmacy. Quantum entanglement, which allows for instantaneous relationships between particles, can be utilized for secure …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 72–77 Read article
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A Retrospective Analysis of Resin-Based Polymer Composites and Bioactive Glass-Polymer Hybrids Regarding Secondary Caries and Durability
Abstract: Aim- To compare the 2-year clinical survival and failure modes of a Resin-Based Polymer Composites and BioactiveGlass-Polymer Hybrids in Class I and II posterior restorations. Methods-A total of 550 restorations were placed in adult patients across various private dental practices in India to ensure a diverse clinical demographic. Teeth were randomly assigned and restored with either a hybrid composite (Te-Econom, IvoclarVivadent; n=275) or a Resin-Modified Glass Ionomer Cement (GC Gold …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1089–1095 Read article
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Valeriana Jatamansi in Ailment of Various Diseases: A Review
Abstract: V. wallichii, often known as Valeriana jatamansi, is a significant medicinal herb. The word ‘Valerian’, which is derived from the word ‘Velo’ means ‘strong drug’, was originally used by an Indian doctor in the ninth century. This review focus on their geographical characterization, botanical characterization, traditional uses, and their mechanism of action on various bioactivity. This review discusses the major bioactive constituents and their 2D and 3D structures. V. jatamansi …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 3, 2024 · pp. 1–13 Read article
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Influence of Antibiotic Promotion Practices on Pharmacovigilance and Resistance Reporting Patterns
Abstract: The global escalation of antimicrobial resistance (AMR) has emerged as a critical public health crisis, undermining decades of therapeutic advancements. While inappropriate prescribing and misuse of antibiotics are widely acknowledged contributors, the role of pharmaceutical promotion practices remains underexplored in influencing prescribing behaviors and downstream pharmacovigilance systems. This review critically examines how antibiotic promotion strategies – ranging from direct physician engagement to digital marketing – affect adverse drug reaction (ADR) …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 · pp. 1–11 Read article
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Targeting TNFSF4 in the Management of Systemic Lupus Erythematosus
Abstract: Systemic lupus erythematosus (SLE) is a multifaceted autoimmune disorder that remains a significant challenge for both healthcare providers and researchers. Despite advances in understanding its mechanisms, finding effective therapies is still difficult. This review highlights a potential therapeutic target in SLE research: tumor necrosis factor superfamily member 4 (TNFSF4), also referred to as OX40L. We explore how TNFSF4 contributes to SLE development, looking at its role in immune system regulation …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 3, 2024 · pp. 6–14 Read article
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Design and Manufacturing of Suspension and Steering System of a F3 Vehicle
Abstract: The suspension and steering systems are critical subsystems of any formula-style racing vehicle, directly influencing its stability, handling, and driver safety. This paper focuses on the design, analysis, and manufacturing of suspension and steering systems for a Formula Student F3 vehicle. The primary objective is to develop a lightweight, reliable, and efficient design that complies with Formula Student competition rulebooks while ensuring optimum ride quality and performance. Using advanced computer-aided …
Published in Trends in Mechanical Engineering & Technology · Vol. 15, Issue 3, 2025 · pp. 1–12 Read article
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Hardware Synchronization for Embedded Multi-core Processors
Abstract: The focus is not on whether multi-core systems are becoming prevalent, but on how microcontroller architectures should be designed to comply with stringent field requirements. This paper illustrates the transition from single to multiple cores, ensuring coherence and consistency in shared memory through hardware mechanisms. Hardware barriers are implemented to allow for point-to-point synchronization between processor cores. Practical experiments center on the initial stages of transforming single-core systems into dual-core …
Published in Journal of VLSI Design Tools and Technology · Vol. 14, Issue 1, 2024 · pp. 33–42 Read article
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Structure–Property Modeling of Cement-Based Multi-Component Composites Using Ensemble Machine Learning and Explainable Feature Attribution
Abstract: Accurate prediction of compressive strength is central to structure–property optimization, quality control, and sustainability-driven design in cement-based composite materials. Cementitious systems represent heterogeneous multi-phase composites composed of reactive binder matrices and dispersed aggregate phases, whose macroscopic mechanical performance emerges from complex nonlinear interactions among constituents and curing-dependent microstructural evolution. This study develops a data-driven structure–property modeling framework to quantify the nonlinear dependence of compressive strength on multi-component composite composition and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 112–131 Read article
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Seismic Analysis of Base Isolation for Protection of Rural Building of Different Shapes
Abstract: India is a developing country, more than 50% of Indian population lives in unreinforced masonry structures. Masonry structures are vulnerable to seismic loading and load acting in it’s out of plane, hence performs poorly and sometimes leads to sudden collapse. Collapse of structure not only damages public property but also costs the lives of people. Base isolation techniques for these types of structure can be proven to be beneficial, in …
Published in Journal of Structural Engineering and Management · Vol. 11, Issue 2, 2024 · pp. 32–43 Read article
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Nanocarrier-mediated CRISPR/Cas9 Gene Editing of BMP2 for Bone Repair
Abstract: The growth factor that plays an important role in the formation and repair of bones is bone morphogenetic protein 2(BMP2). Nevertheless, because BMP2 is rapidly degrading and has less than half the time to live, its delivery into bone defects may be difficult. A plan to develop a nanocarrier via CRISPRCas9 gene editing mechanism for the delivery of BMP2 into bone defects is outlined in this research proposal. The system …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 1, 2025 · pp. 14–21 Read article
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AI Application in the Creation of Medications for COPD
Abstract: The crippling lung condition known as chronic obstructive pulmonary disease (COPD) is typified by a continuous restriction of airflow, which results in increased respiratory dysfunction and a reduced quality of life. The rising incidence of COPD worldwide emphasizes the pressing need for innovative pharmaceutical approaches to address the illness. Even though COPD care has advanced significantly, most current medications concentrate on symptom relief rather than disease change. This gap in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 01–05 Read article
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Development of Solar-Powered Automated Floating Type Oil Skimmer
Abstract: Solar-powered automatic floating oil skimmer oil spills are one of the most pressing environmental issues because they cause significant damage to marine environments. The development of a solar- powered automated floating oil skimmer offers an efficient and sustainable solution for oil spill removal. Powered primarily by solar energy, the system operates continuously without reliance on external power sources, making it ideal for remote or offshore locations. Its automated design reduces …
Published in Journal of Alternate Energy Sources & Technologies · Vol. 16, Issue 3, 2025 · pp. 29–35 Read article
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Efficient Data Backup and Recovery Automation Using Shell Scripts in UNIX Systems
Abstract: Data backup and recovery constitute essential components of system administration in UNIX-based environments, playing a critical role in maintaining data integrity, ensuring continuous availability, and providing resilience against various forms of data loss. In modern computing systems, data is a vital asset, and its loss—whether due to hardware failures, software corruption, human error, or cyber threats—can lead to significant operational disruptions and financial consequences. Therefore, implementing reliable and efficient backup …
Published in Journal of Advances in Shell Programming · Vol. 13, Issue 1, 2026 · pp. 48–54 Read article
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Host-Pathogen Coevolution: Implications for Immune Evasion and Pathogen Fitness
Abstract: The interaction between hosts and pathogens represents a continuous evolutionary struggle, shaping both microbial virulence and host immunity. Pathogens employ diverse strategies to evade immune surveillance, ranging from antigenic variation and molecular mimicry to hijacking of host immune checkpoints. Simultaneously, hosts refine innate and adaptive immune mechanisms to counteract infection and limit damage. This reciprocal adaptation, known as host–pathogen coevolution, influences pathogen persistence, transmission, and fitness, while also sculpting immune …
Published in International Journal of Pathogens · Vol. 2, Issue 2, 2025 · pp. 6–10 Read article
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Host Invasion to Immune Evasion: Emerging Concepts in Pathogen Virulence Strategies
Abstract: The interaction between hosts and pathogens represents a continuous evolutionary struggle, shaping both microbial virulence and host immunity. Pathogens employ diverse strategies to evade immune surveillance, ranging from antigenic variation and molecular mimicry to hijacking of host immune checkpoints. Simultaneously, hosts refine innate and adaptive immune mechanisms to counteract infection and limit damage. This reciprocal adaptation, known as host–pathogen coevolution, influences pathogen persistence, transmission, and fitness, while also sculpting immune …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 Read article