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1455 articles for “responsibility”
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DMARDs, Biologic Agents and Novel Experimental Strategies in The Treatment of Rheumatoid Arthritis
Abstract: An inflammatory and autoimmune disease, rheumatoid arthritis (RA) causes severe pain and inflammation in affected areas of the body. According to the report, there is no known cure for RA. Therefore, reducing discomfort and halting future harm must be the goals of present therapy. For the purpose of prevention and to reduce disease activity in RA patients, significant success has been achieved with the continued development of disease-modifying antirheumatic drugs …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 14–24 Read article
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Evaluation of the anti diabetic effects of ethanolic root extract from polyalthania longifora in diabetic rats induced by streptozotin and nicotinamide with considaertion of toxocological aspects
Abstract: The root of Polialthia Longifolia was selected for the evaluation of antidiabetic potential in STZ-nicotinamide induced diabetic rat model.The root extract was extracted by hot percolation using ethanol as a solvent in soxhlet apparatus and the preliminary phytochemical screening was performed and it shows that the ethanolic root extract of Polialthia Longifolia contains alkaloids, glycosides, flavonoids and tannins. Safety profile is essential for the drugs obtained from the plant origin. …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 37–50 Read article
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Exploring the Thyroid Gland Physiology in Relation to Thyroid Hormones: An Overview through the Lens of 3D Computational Biology
Abstract: The endocrine system plays a pivotal role in orchestrating and sustaining diverse physiological functions by manufacturing and releasing hormones, which function as vital chemical messengers within the body. Among the prominent endocrine glands, the thyroid gland holds a central position. Situated in the lower part of the neck, this gland adopts a butterfly-shaped structure. Its significance lies in the synthesis of three key hormones: thyroxine (T4), tri-iodothyronine (T3), and calcitonin.The …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 1, 2024 · pp. 46–54 Read article
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REPEATED MOPs VS DUAL APPROACH IN ACCELERATED ORTHODONTICS
Abstract: In contemporary orthodontics, there is a pressing need to minimize treatment duration, which is often a concern for both orthodontic specialists and patients. Prolonged treatment periods not only pose logistical challenges but also increase the risks of various dental issues such as cavities, periodontal problems, chronic discomfort, and root resorption. Accelerated orthodontics has emerged as a promising solution to address these challenges. Numerous efforts have been undertaken to expedite orthodontic …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 1, 2024 · pp. 16–21 Read article
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Deciphering Th-Related Gene Interactions in Chronic Spontaneous Urticaria: Bioinformatics Insights and Drug Affinity Exploration
Abstract: Objective: There has been a great deal of interest in how inflammatory dermatosis and The cell interact, but the etiopathogenesis of chronic spontaneous urticaria (CSU) is still inadequately comprehended. Through bioinformatics techniques, the purpose of this work is to elucdate the molecular mechanism underlying Th-related genes in CSU and seeks to find the highest affinity drug. Methods: The CSU RNA expression profiling dataset provided the basis for the investigation. The …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 1–15 Read article
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Antibacterial Multi-Herbal Hand Sanitizer Description and Review
Abstract: Many hand sanitizers on the market contain alcohol formulations that can lead to various issues. In response, we have focused on developing alternative hand washing solutions using detergents to address problems such as dermatitis, itching, dryness, and irritation. Our current efforts involve creating a range of hand sanitizers enriched with ingredients like aloe vera gel, Rita, Azadirachta indica, holy basil, reetha fruit, eucalyptus (Nilgiri), rose, and citrus fruits. Additionally, we …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 1, 2024 · pp. 10–16 Read article
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Psychological Trauma Reflected in B.Rangarao’s Dalit Short Story Death of a Rich Man
Abstract: In the growing expansion of marginalized literature, B.Rangarao’s short story collection “Desperate Men and Women: Ten Dalit Short Stories from India” has been greatly applauded by the readers as it brilliantly exposed the trauma of both men and women of Dalit community in autocratic conditions in India. In Dalit writing Rangrao’s contribution gave fresh look especially to the short story genre as it is based on the revolutionary ideas of …
Published in Emerging Trends in Languages · Vol. 1, Issue 1, 2024 · pp. 01–07 Read article
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Breaking Barriers: How Telemedicine is Reshaping Access and Quality in Healthcare
Abstract: Thanks to advancements in telecommunications technology, telemedicine has become a disruptive force in the delivery of healthcare, bridging geographical and accessibility gaps. This article offers a thorough examination of the advantages, difficulties, and potential applications of telemedicine in healthcare. Telemedicine has a number of benefits, one of which is that it makes healthcare more accessible, especially for underprivileged groups living in rural or isolated places. Telemedicine makes it possible for …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 1–4 Read article
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Workplace with better Health, Safety, and Environment for Organizational Well-being
Abstract: In the realm of workplaces, prioritizing the welfare of employees and upholding environmental protection has gained utmost significance. There are multifaceted approaches to achieving a harmonious balance between workplace health, safety, and environmental sustainability. For the better Health, Safety and Environment, the integration of comprehensive policies, cutting-edge technologies, and a culture of continuous improvement to foster a secure, healthy, and environment are essential. The evolutions of workplace health and safety …
Published in International Journal of Pollution: Prevention & Control · Vol. 2, Issue 1, 2024 · pp. 1–6 Read article
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A Comprehensive Review On Panic Disorders
Abstract: Panic disorder is a prevalent mental health condition characterized by sudden, recurring episodes of intense fear accompanied by physical symptoms. It is twice as likely to affect women and may have a genetic predisposition. This disorder stems from an exaggerated response of the body's survival mechanisms and hormones, impacting manifestations like agoraphobia. Additionally, it is associated with significant psychiatric comorbidity and impaired functioning in various roles. Recent research has delved …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 1, 2024 · pp. 53–59 Read article
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Personalized Nutrition and Exercise: Pioneering the Path to Precision Medicine
Abstract: Preventive healthcare is about to undergo a major shift thanks to the personalised exercise and nutrition paradigm, which is based on precision medicine concepts. In order to create tailored recommendations for improving health outcomes and preventing chronic diseases, this article explores the integration of genetic profiling, metabolic evaluation, and lifestyle factors. A person's response to food and exercise depends heavily on genetic and metabolic variances, which emphasises the need of …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 2, 2024 · pp. 42–46 Read article
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Revisiting the Role of Mindfulness-based Stress Reduction in the Management of Rheumatoid Arthritis
Abstract: Rheumatoid arthritis (RA) is a type of arthritis characterized by a chronic inflammatory disorder that primarily affects the lining of the synovial joints resulting in progressive disability in the movement of diarthrodial joints and arthralgia. It is a debilitating disease associated with premature death and socioeconomic burdens. Its pathogenesis is multifactorial with an individual course of progression where psychological stress is considered to be one of the risk factors associated …
Published in International Journal of Vaccines · Vol. 1, Issue 1, 2024 · pp. 19–28 Read article
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The Rise of AI in E-Commerce: Transforming Shopping Experiences
Abstract: The field of e-commerce is transforming due to the integration of artificial intelligence, offering businesses fresh possibilities to enhance customer experiences, streamline operations, and foster expansion. This article explores the transformative impact of artificial intelligence (AI) on various aspects of e-commerce, including personalized shopping experiences, intelligent chatbots and virtual assistants, predictive analytics for inventory management, dynamic pricing strategies, visual search and image recognition, fraud detection, and security measures, augmented reality …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 11, Issue 1, 2024 · pp. 22–26 Read article
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Formulation and Evaluation of Aqueous Azadirachta indica Phytosome
Abstract: A phytosome is a complex created through the union of a natural compound, typically a plant extract, with a phospholipid. Phospholipids play a crucial role in cell membranes, possessing a structure comprising a hydrophilic (water-attracting) head and hydrophobic (water-repelling) tails. This distinctive structure enables phospholipids to construct lipid bilayers, fundamental elements of cell membranes. Phytosome increases the bioavailability, and absorption of active chemical constituents in the extract with the help …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 1, 2024 · pp. 17–30 Read article
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Stretching Boundaries: A Comprehensive Review of Ehlers-Danlos Syndrome and its Subtypes
Abstract: The Ehlers-Danlos syndromes (EDS) encompass 13 inheritable disorders affecting connective tissue. These conditions arise from genetic alterations impacting the structure of connective tissue. Every variant of Ehlers-Danlos syndrome (EDS) exhibits distinct features and has specific diagnostic criteria. While certain traits such as joint hypermobility, skin hyperextensibility, and tissue fragility are common across all types of EDS. The range of clinical presentations spans from minor skin and joint looseness to severe …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 44–57 Read article
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Development of Anti IgG Polyclonal Antibody Against Canine IgG and Their Roles in Diagnostic Purposes
Abstract: IgG plays an important part in immunological studies and also in living bodies for providing secondary immune response which triggers as passive immunization against harmful pathogens in dogs. Purpose: The aim of this investigation is to separate, identify, and refine immunoglobulin G from canine serum. Methods: Ammonium sulphate precipitation was used to separate the dog's serum, which was then concentrated over night in a dialysis bag inside of a refrigerator. …
Published in International Journal of Vaccines · Vol. 1, Issue 2, 2024 · pp. 01–06 Read article
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Cause of climate change and issues in uttrakhand
Abstract: Uttarakhand is experiencing a surge in average temperatures and a significant shift in precipitation regime, causing significant changes in the duration, amount, and form of atmospheric precipitation. The region's shorter snowfall season is believed to be responsible for decreased water supply, leading to water scarcity. The shift in plant blossoming and fruiting has also led to a shift in traditional life support activities, resulting in decreased agricultural productivity, increased pest …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 2, Issue 1, 2024 · pp. 21–26 Read article
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Effects of Gypsophila on Airway Inflammation in Guinea pig model of ovalbumin‐induced Asthma
Abstract: To look at how Gypsophlia (GSP) affects airway inflammation in a model of ovalbumin-induced asthma in guinea pigs (OVA).Methods: Using a random number table, sixty healthy female guinea pigs were split into six groups, each consisting of ten rats: the normal control, OVA, and GSP (0.45, 0.9, 1.8, and 3.6 g/kg). The ovalbumin and lipopolysaccharide sensitization approach was used to create the OVA guinea pig model. The GSP groups received …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 1, 2024 · pp. 17–23 Read article
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Vaccination in the Era of Precision Medicine: Tailoring Immunization Strategies for Individual Risk Profiles
Abstract: The introduction of precision medicine has caused a paradigm change in the vaccine landscape. Conventionally, vaccination programmes have been homogeneous, targeting immunity at the population level without taking into consideration the individual differences in immune response and vulnerability to diseases that can be prevented by vaccination. However, a more individualised approach to immunisation has been made possible by current developments in genetics, immunology, and data analytics. Within the context of …
Published in International Journal of Vaccines · Vol. 1, Issue 2, 2024 · pp. 32–47 Read article
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Performance Evaluation of Eco-friendly Cutting Fluid in Machining Process—An Approach towards Environmentally Friendly Production
Abstract: The machining industry's evolving environmental consciousness has prompted a growing demand for cutting fluids devoid of chlorine and sulphur, thus fostering sustainable machining practices. This surge in demand is driven by mounting apprehensions over environmental contamination and worker safety. As the industry transitions to modern cutting fluids, it becomes imperative to comprehend their effectiveness and the optimal machine parameters required for their deployment in the turning process. In our current …
Published in Journal of Polymer & Composites · Vol. 11, Issue 12, 2023 · pp. 149–160 Read article