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907 articles for “Strategic Approach”
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Metagenome-Informed Engineering of Monoclonal Antibodies: Mining Microbial Immunoglobulin-Like Domains for Ultra-Stable Therapeutics
Abstract: Metagenome-informed engineering represents an emerging strategy for improving the stability and functionality of monoclonal antibodies (mAbs) by leveraging the vast diversity of microbial immunoglobulin-like (Ig-like) domains (10,24). These domains, derived from uncultured bacteria and bacteriophages, exhibit exceptional thermostability, protease resistance, and structural resilience due to adaptation to extreme environments (29,30). This review highlights advances in metagenomic mining, structural characterization, and protein engineering that enable the integration of microbial Ig-like scaffolds …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 · pp. 70–83 Read article
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Nutritional Enhancements in Dairy Products
Abstract: Dairy products play a crucial role in diets globally, providing key nutrients like proteins, fats, vitamins, and minerals. However, with evolving dietary needs and a growing focus on public health, the fortification of dairy products has emerged as a critical strategy to enhance their nutritional profile. This review explores the fortification of dairy products with vitamins, minerals, probiotics, and other health-promoting ingredients, examining the methods, benefits, challenges, and future prospects …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 13, Issue 2, 2024 · pp. 18–23 Read article
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Optimization of Production Processes to Minimize Waste and Improve Efficiency in Automobile Servicing Plant Using Lean Six Sigma
Abstract: This study focuses on optimizing production processes within an automobile servicing plant to minimize waste and enhance efficiency through the application of lean six sigma (LSS) methodologies. Utilizing a case study approach, the research addresses real-time challenges related to productivity and waste reduction. Data collection involves assessing machine functionality metrics, material and labor flow at various stages of the servicing process. The optimization strategy integrates lean tools including value stream …
Published in International Journal of Manufacturing and Production Engineering · Vol. 2, Issue 2, 2024 · pp. 47–63 Read article
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Neuro-Rehabilitation Reimagined: A Cross-Cultural Paradigm Integrating Immunotherapeutics and Multidimensional Analytics in Pediatric Cerebral Palsy
Abstract: Researchers performed multidimensional data analysis on the clinical records of 1,586 cerebral palsy pediatric patients to investigate the rehabilitative benefits of immunotherapy and the advantages of blending Traditional Chinese Medicine with Western treatments. A multi-center, prospective cohort study established a standardized system for data gathering that included clinical baseline databases along with treatment protocols and follow-up information. Baseline data analysis showed substantial patient diversity across clinical types and TCM syndromes …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 67–84 Read article
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Green and Edge-Aware Computing: Rethinking Cloud Infrastructure for Sustainability
Abstract: Cloud computing has transformed the way organizations access and manage information technology resources, providing flexible, scalable, and cost-efficient services that support today’s data-driven world. Despite these advantages, the rapid expansion of large-scale cloud infrastructures has resulted in rising energy consumption, significant heat generation, and a growing environmental footprint. This research focuses on advancing green cloud computing by examining methods that reduce power usage while maintaining high performance. Key strategies include …
Published in Journal of Computer Technology & Applications · Vol. 17, Issue 1, 2026 · pp. 17–24 Read article
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A Review on AI and Machine Learning for Predictive Maintenance and FDD in RAC Systems
Abstract: The paper reviews the existing AI/ML methods first in the general context of predictive maintenance and FDD of RAC systems, then specifically focusing on granular cooling appliances. Perspectives and insights are provided on the reasons why potentially valuable models do not make it into practice more often, and where future research and development should be headed. New emerging topics for decision support systems to include domain knowledge and physics-based modeling …
Published in Journal of Refrigeration, Air conditioning, Heating and ventilation · Vol. 13, Issue 1, 2026 · pp. 15–25 Read article
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Concept Maps as an Educational Strategy to Enhance Critical Thinking among Student Nurses
Abstract: A quasi experimental study to assess the effectiveness of concept maps as a teaching strategy to facilitate critical thinking among student nurses with regard to congenital heart defects was conducted with primary objective to assess effectiveness of concept maps as a teaching strategy on critical thinking of student nurses with regard to congenital heart defects. Ethical clearance from the Institutional Review Board was obtained. The conceptual framework adopted was Stufflebeam’s …
Published in Journal of Nursing Science & Practice · Vol. 4, Issue 1, 2014 · pp. 30–37 Read article
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The Quiet Intruder: An Insidious Presentation of Primary Plasma Cell Leukemia and a Literature Review on Current Treatment Strategies
Abstract: Introduction: Primary plasma cell leukemia (pPCL) is a rare and aggressive plasma cell dyscrasia, defined by ≥5% circulating plasma cells, with poor prognosis and rapid progression. Case Presentation: A 66-year-old African–American female with no prior medical history presented with one week of fatigue, dehydration, and polydipsia. Laboratory evaluation revealed leukocytosis, severe thrombocytopenia, acute kidney injury (creatinine 4.03 mg/dL), and hypercalcemia (13.0 mg/dL) with suppressed PTH. Imaging showed intra-abdominal lymphadenopathy without …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 2, 2026 · pp. 1–5 Read article
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Reproductive Challenges in Tropical Dairy Cows: Exploring Stressors and Mitigation Strategies for Sustainable Development
Abstract: Reproductive efficiency in tropical dairy cows is often compromised by a range of environmental, nutritional, and management-related stressors. These stressors, including heat, humidity, poor-quality feed, disease, and parasitic infestations, significantly affect fertility, leading to prolonged calving intervals, reduced conception rates, and increased reproductive disorders. Heat stress, in particular, has been identified as a primary factor influencing reproductive performance by disrupting hormonal balance, reducing feed intake, and impairing overall cow health. …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 15, Issue 2, 2026 · pp. 7–26 Read article
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Codal Validation and Optimization of Gantry Girders Under Variable Wheelbase and Impact Loads: A Review of Analytical, Numerical, and Codal Approaches
Abstract: Gantry girders serve as critical structural elements in industrial facilities such as steel plants, workshops, and heavy manufacturing units, where electric overhead traveling (EOT) cranes operate. The design of these girders is governed by stringent codal provisions to ensure safety under bending, shear, and deflection. However, discrepancies between codal predictions, analytical formulations, and finite element analysis (FEA) results, particularly under variable wheelbase and dynamic impact loads, have been widely reported. …
Published in Journal of Offshore Structure and Technology · Vol. 12, Issue 3, 2025 · pp. 23–29 Read article
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A Study to Evaluate the Impact of Health Education on Awareness of Long-term Complications of Hypertension Among Hypertensive Patients in A Selected Hospital, Bengaluru
Abstract: The rising burden of non-communicable diseases, particularly hypertension, poses significant public health challenges, especially in developing nations. This study aimed to assess the effectiveness of a health education program focused on lifestyle modifications to prevent hypertension-related complications among patients at selected hospitals in Bengaluru. Employing a quasi-experimental design, we recruited 60 hypertensive patients through purposive sampling. Initial knowledge was evaluated using a structured questionnaire, followed by an educational intervention provided …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 31–63 Read article
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The Role of Natural Products in Antiviral Drug Discovery: Insights into Mechanisms and Therapeutic Potential
Abstract: Drug discovery has always relied heavily on natural sources, especially when it comes to creating antiviral medications. This review explores the therapeutic potential of various natural products, including plant extracts, marine compounds, and microbial metabolites, in the fight against viral infections. We examine the mechanisms of action by which these natural compounds exert their antiviral effects, including direct inhibition of viral replication, modulation of host immune responses, and interference with …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 36–47 Read article
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SDG 15: Life on Land-Challenges in Sustainable Utilization and Conservation of Water Resources
Abstract: Water is one of the most essential natural resources for sustaining life, ensuring agricultural productivity, and fostering socio-economic development. Its effective management and utilization are critical to reducing poverty, maintaining a stable climate, and promoting sustainable economic growth. However, increasing pressures from population growth, urbanization, and industrialization have significantly intensified the demand for water, creating numerous challenges. These include a decline in per capita water availability, falling groundwater levels in …
Published in Journal of Water Resource Engineering and Management · Vol. 12, Issue 1, 2025 · pp. 35–42 Read article
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The Effect of Attachment Styles on Emotional Regulation Impacting Relationship Satisfaction: An Exploratory Case Study Design
Abstract: This study explores the impact of early attachment experiences, emotional regulation, and relationship dynamics among six participants through a qualitative case study approach. Using thematic and narrative analyses, the research identifies key patterns in emotional suppression, fear of abandonment, trust issues, and self-awareness. Participants' narratives reveal how childhood experiences with caregivers influenced their emotional regulation strategies and attachment styles in adulthood. Findings indicate that those with secure emotional upbringings exhibited …
Published in International Journal of Behavioral Sciences · Vol. 2, Issue 2, 2025 · pp. 1–17 Read article
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Smart-Waste-Management-System
Abstract: The rapid urbanization and increasing waste generation pose significant challenges to traditional waste management systems, necessitating innovative solutions that integrate economic principles and management strategies. In order to enhance trash transportation and recycling procedures, this paper investigates the deployment of a Smart trash Management System that makes use of Internet of Things (IoT) components and machine learning algorithms. By applying economic principles such as cost-benefit analysis and resource allocation, and …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 3, Issue 2, 2025 · pp. 18–27 Read article
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Immune Dysregulation and Cytokine Circuitry in Genital Endometriosis: Mechanistic Insights and Next-Generation Immunotherapeutic Strategies
Abstract: Genital endometriosis is increasingly recognized as an immune-mediated inflammatory disorder driven by complex interactions between dysregulated immune cells, cytokine hubs, and microbiome-derived modulators. This review introduces a novel “immune–cytokine circuitry” framework that unifies innate and adaptive immune abnormalities with key cytokine loops sustaining chronic inflammation, angiogenesis, neuroinflammation, and immune tolerance. Within this circuitry, macrophage polarization, dendritic cell immaturity, NK-cell anergy, Treg expansion, Th17 amplification, and B-cell–mediated autoimmunity converge to establish …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 06–16 Read article
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Reduction of Air Pollutants of Urban Canyons through Management of Particulate Matters 2.5 in the Streets
Abstract: Urban canyons are long and high sky-scrappers closely to narrow streets result in very different microclimate challenges. These spaces often trap pollutants and restrict air circulation and intensify more retention of heat making them very uncomfortable for pedestrians. In order to resolve this issue a strong set of design guidelines and frameworks were needed which can balance out the human comfort and environmental aspects. This research studies strategies to improve …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 3, Issue 1, 2025 · pp. 11–23 Read article
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VIGILENS-An Innovative Anti Sleep and Alert System
Abstract: This project aims to create an advanced Anti-Sleep Alarm System meticulously crafted to detect and mitigate the dangers of driver fatigue in real-time. Designed with a keen focus on both effectiveness and ease of implementation, Vigilens offers a comprehensive approach to enhancing road safety for all. Central to Vigilens is its utilization of cutting-edge technology housed within a pair of specially engineered goggles. These goggles are equipped with a sophisticated …
Published in Recent Trends in Sensor Research & Technology · Vol. 10, Issue 3, 2023 · pp. 19–28 Read article
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Effectiveness of Practice-Based Professional Development in Enhancing Stem Teachers
Abstract: STEM is about science technology engineering and math all put together in school work. Small group talks are seen as a good way to help students learn in these classes but it depends on things like how much the teacher knows about the topic and whether they feel ready to lead the talks. We looked at photovoltaics for this which mixes all the STEM areas and connects to solar power …
Published in International Journal of Trends in Humanities · Vol. 3, Issue 2, 2026 · pp. 30–35 Read article
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Advancements in Analytical Techniques and Validation Methods for Pharmaceutical Tablet Formulations Using HPTLC
Abstract: High Performance Thin Layer Chromatography (HPTLC) is a versatile analytical technique which has been effectively used for pharmaceutical quality control and cost effectively, rapidly, and high throughput analyzed tablet formulations. HPTLC is different from traditional chromatographic methods as multi sample analysis is possible in one run with low consumption of solvent, which are principles of green analytical chemistry. But existing HPTLC is limited in sensitivity, resolution and reproducibility and these …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 3, 2026 Read article